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Physical activity, cardiovascular disease, and mortality across obesity levels
Physical activity, cardiovascular disease, and mortality across obesity levels
High physical activity (PA) is associated with decreased risk of cardiovascular disease (CVD) and mortality. However, whet...
Prediction of risk for isolated incomplete lateral meniscal injury using a dynamic nomogram based on MRI-derived anatomic radiomics and physical activity: a proof-of-concept study in 3PM-guided management
Prediction of risk for isolated incomplete lateral meniscal injury using a dynamic nomogram based on MRI-derived anatomic radiomics and physical activity: a proof-of-concept study in 3PM-guided management
The 3PM framework revolutionizes disease management by facilitating early risk prediction, disease prevention, and persona...
Association of prebiotic/probiotic intake with MASLD: evidence from NHANES and randomized controlled trials in the context of prediction, prevention, and a personalized medicine framework
Association of prebiotic/probiotic intake with MASLD: evidence from NHANES and randomized controlled trials in the context of prediction, prevention, and a personalized medicine framework
Metabolic-associated fatty liver disease (MASLD) is a growing global health concern. From the standpoint of preventive and...
Mass spectrometry-based analysis of eccrine sweat supports predictive, preventive and personalised medicine in a cohort of breast cancer patients in Austria
Mass spectrometry-based analysis of eccrine sweat supports predictive, preventive and personalised medicine in a cohort of breast cancer patients in Austria
Metabolomics measurements of eccrine sweat may provide novel and relevant biomedical information to support predictive, pr...
Mitochondria in cutaneous health, disease, ageing and rejuvenation—the 3PM-guided mitochondria-centric dermatology
Mitochondria in cutaneous health, disease, ageing and rejuvenation—the 3PM-guided mitochondria-centric dermatology
Association of both intrinsic and extrinsic risk factors leading to accelerated skin ageing is reflected in excessive ROS ...
Advancing predictive, preventive, and personalized medicine in eyelid diseases: a concerns-based and expandable screening system through structural dissection
Advancing predictive, preventive, and personalized medicine in eyelid diseases: a concerns-based and expandable screening system through structural dissection
Early recognition of eyelid morphological abnormalities was crucial, as untreated conditions could lead to blinding compli...
Characterization of the gut microbiota in drug abuse: prediction, prevention, and personalized medicine to benefit affected populations
Characterization of the gut microbiota in drug abuse: prediction, prevention, and personalized medicine to benefit affected populations
Drug abuse poses an enormous threat to global public health. Long-term drug abuse can reduce the quality of life of patien...
Monoclonal antibody immune therapy response instrument for stratification and cost-effective personalized approaches in 3PM-guided pan cancer management
Monoclonal antibody immune therapy response instrument for stratification and cost-effective personalized approaches in 3PM-guided pan cancer management
Immune checkpoint inhibitors (ICIs), such as anti-PD-1, anti-PD-L1, and anti-CTLA-4 therapies, have revolutionized cancer ...
Microalgae and exercise: from molecular mechanisms and brain health to clinical perspectives in the context of 3P medicine
Microalgae and exercise: from molecular mechanisms and brain health to clinical perspectives in the context of 3P medicine
Microalgae are emerging as innovative bioresources with diverse therapeutic applications, particularly in cardiovascular h...
Acute mountain sickness prediction: a concerto of multidimensional phenotypic data and machine learning strategies in the framework of predictive, preventive, and personalized medicine
Acute mountain sickness prediction: a concerto of multidimensional phenotypic data and machine learning strategies in the framework of predictive, preventive, and personalized medicine
Acute mountain sickness (AMS) is a self-limiting illness, involving a complex series of physiological responses to rapid a...
Development and validation of a prediction model for the depressive symptom risk in commercial airline pilots
Development and validation of a prediction model for the depressive symptom risk in commercial airline pilots
Shift workers, such as medical personnel, and pilots, are facing an increased risk of depressive symptoms. Depressive symp...
Targeting the MAPK signaling pathway: implications and prospects of flavonoids in 3P medicine as modulators of cancer cell plasticity and therapeutic resistance in breast cancer patients
Targeting the MAPK signaling pathway: implications and prospects of flavonoids in 3P medicine as modulators of cancer cell plasticity and therapeutic resistance in breast cancer patients
Cancer drug resistance poses a significant challenge in oncology, primarily driven by cancer cell plasticity, which promot...
Beyond hormones: 3PM approach to vaginal microbiota dynamics in postmenopausal women
Beyond hormones: 3PM approach to vaginal microbiota dynamics in postmenopausal women
Menopause marks a critical transition characterized by ceased ovarian function and declining estrogen levels, affecting mu...
Mitochondrial medicine: “from bench to bedside” 3PM-guided concept
Mitochondrial medicine: “from bench to bedside” 3PM-guided concept
Mitochondria are the primary sites for aerobic respiration and play a vital role in maintaining physiologic function at th...
IgG N-glycosylation contributes to different severities of insulin resistance: implications for 3P medical approaches
IgG N-glycosylation contributes to different severities of insulin resistance: implications for 3P medical approaches
Reliable biomarkers capturing immunometabolic processes in insulin resistance (IR) remain limited. IgG N-glycosylation mod...
Comprehensive genome-wide analysis of retinal vessel caliber reveals microvascular-blood pressure pathways: advancing predictive, preventive, and personalized medicine
Comprehensive genome-wide analysis of retinal vessel caliber reveals microvascular-blood pressure pathways: advancing predictive, preventive, and personalized medicine
Retinal vessel caliber is strongly associated with systemic blood pressure (BP); however, the causal relationship between ...
Vision transformer-based stratification of pre/diabetic and pre/hypertensive patients from retinal photographs for 3PM applications
Vision transformer-based stratification of pre/diabetic and pre/hypertensive patients from retinal photographs for 3PM applications
Diabetes and hypertension pose significant health risks, especially when poorly managed. Retinal evaluation though fundus ...
The 3PM transformation potential of minimal residual disease in solid tumor management: a bibliometric analysis and review
The 3PM transformation potential of minimal residual disease in solid tumor management: a bibliometric analysis and review
Over the past two decades, significant progress has been made in the study of minimal residual disease (MRD) in patients w...
Systemic inflammation at the oral–ocular interface: a 3P medicine perspective on the relationship between periodontitis and eye diseases
Systemic inflammation at the oral–ocular interface: a 3P medicine perspective on the relationship between periodontitis and eye diseases
Periodontitis is a common source of chronic systemic inflammation, driven by bacterial translocation and cytokine release ...
The mediating effect of perceived stress on the relationship between big five personality traits and suboptimal health status in Chinese population: a nationwide survey in the framework of predictive, preventive, and personalized medicine
The mediating effect of perceived stress on the relationship between big five personality traits and suboptimal health status in Chinese population: a nationwide survey in the framework of predictive, preventive, and personalized medicine
The effects of psychological factors on suboptimal health status (SHS) have been widely described; however, mechanisms beh...
Automated detection of nine infantile fundus diseases and conditions in retinal images using a deep learning system
Automated detection of nine infantile fundus diseases and conditions in retinal images using a deep learning system
We developed an Infant Retinal Intelligent Diagnosis System (IRIDS), an automated system to aid early diagnosis and monito...
Frailty mediating the causality between leucocyte telomere length and mortality: a cohort study of 440,551 UK Biobank participants
Frailty mediating the causality between leucocyte telomere length and mortality: a cohort study of 440,551 UK Biobank participants
Previous studies reported leucocyte telomere length (LTL) and frailty were associated with mortality, but it remains uncle...
Cancer screening in hospitalized ischemic stroke patients: a multicenter study focused on multiparametric analysis to improve management of occult cancers
Cancer screening in hospitalized ischemic stroke patients: a multicenter study focused on multiparametric analysis to improve management of occult cancers
The reciprocal promotion of cancer and stroke occurs due to changes in shared risk factors, such as metabolic pathways and...
Nitroproteomics is instrumental for stratification and targeted treatments of astrocytoma patients: expert recommendations for advanced 3PM approach with improved individual outcomes
Nitroproteomics is instrumental for stratification and targeted treatments of astrocytoma patients: expert recommendations for advanced 3PM approach with improved individual outcomes
Protein tyrosine nitration is a selectively and reversible important post-translational modification, which is closely rel...
Impacts of a multipurpose outpatient hospital pharmacy in the framework of 3P medicine
Impacts of a multipurpose outpatient hospital pharmacy in the framework of 3P medicine
In recent years, we have been witnessing a change in the performance of hospital pharmacists, aimed at increasing their pa...
Diabetes, glycemic control and arterial stiffness: a real-world cohort study in the context of predictive, preventive, and personalized medicine
Diabetes, glycemic control and arterial stiffness: a real-world cohort study in the context of predictive, preventive, and personalized medicine
Arterial stiffness is a major contributor to morbidity and mortality worldwide. Although several metabolic markers associa...
The predictive, preventive, and personalized medicine of insomnia: gut microbiota and inflammation
The predictive, preventive, and personalized medicine of insomnia: gut microbiota and inflammation
The human gut microbiota (GM) has been recognized as a significant factor in the development of insomnia, primarily throug...
Emerging frontiers of artificial intelligence and machine learning in ischemic stroke: a comprehensive investigation of state-of-the-art methodologies, clinical applications, and unraveling challenges
Emerging frontiers of artificial intelligence and machine learning in ischemic stroke: a comprehensive investigation of state-of-the-art methodologies, clinical applications, and unraveling challenges
At present, stroke remains the second highest cause of death globally and a leading cause of disability. From 1990 to 2019...
Predicting 1-, 3-, 5-, and 8-year all-cause mortality in a community-dwelling older adult cohort: relevance for predictive, preventive, and personalized medicine
Predicting 1-, 3-, 5-, and 8-year all-cause mortality in a community-dwelling older adult cohort: relevance for predictive, preventive, and personalized medicine
Population aging is a global public health issue involving increased prevalence of age-related diseases, and concomitant b...
Conceptualised psycho-medical footprint for health status outcomes and the potential impacts for early detection and prevention of chronic diseases in the context of 3P medicine
Conceptualised psycho-medical footprint for health status outcomes and the potential impacts for early detection and prevention of chronic diseases in the context of 3P medicine
The Suboptimal Health Status Questionnaire-25 (SHSQ-25) is a distinctive medical psychometric diagnostic tool designed for...
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