Buysse DJ. Insomnia JAMA. 2013;309(7):706–16.
Article CAS PubMed Google Scholar
Hertenstein E, Feige B, Gmeiner T, Kienzler C, Spiegelhalder K, Johann A, et al. Insomnia as a predictor of mental disorders: a systematic review and meta-analysis. Sleep Med Rev. 2019;43:96–105.
Matenchuk BA, Mandhane PJ, Kozyrskyj AL. Sleep, circadian rhythm, and gut microbiota. Sleep Med Rev. 2020;53:101340.
Espie CA, Broomfield NM, MacMahon KM, Macphee LM, Taylor LM. The attention-intention-effort pathway in the development of psychophysiologic insomnia: a theoretical review. Sleep Med Rev. 2006;10(4):215–45.
Carney CE, Buysse DJ, Ancoli-Israel S, Edinger JD, Krystal AD, Lichstein KL, et al. The consensus sleep diary: standardizing prospective sleep self-monitoring. Sleep. 2012;35(2):287–302.
Article PubMed PubMed Central Google Scholar
Spielman AJ, Caruso LS, Glovinsky PB. A behavioral perspective on insomnia treatment. Psychiatr Clin North Am. 1987;10(4):541–53.
Article CAS PubMed Google Scholar
Dietch JR, Taylor DJ. Evaluation of the Consensus Sleep Diary in a community sample: comparison with single-channel electroencephalography, actigraphy, and retrospective questionnaire. J Clin Sleep Med. 2021;17(7):1389–99.
Article PubMed PubMed Central Google Scholar
Wesselius HM, van den Ende ES, Alsma J, Ter Maaten JC, Schuit SCE, Stassen PM, et al. Quality and quantity of sleep and factors associated with sleep disturbance in hospitalized patients. JAMA Intern Med. 2018;178(9):1201–8.
Article PubMed PubMed Central Google Scholar
Krystal AD, Ashbrook LH, Prather AA. What is insomnia? JAMA. 2021;326(23):2444.
Rossman J. Cognitive-behavioral therapy for insomnia: an effective and underutilized treatment for insomnia. Am J Lifestyle Med. 2019;13(6):544–7.
Article PubMed PubMed Central Google Scholar
Golubnitschaja O, Kinkorova J, Costigliola V. Predictive, preventive and personalised medicine as the hardcore of “Horizon 2020”: EPMA position paper. EPMA J. 2014;5(1):6.
Article PubMed PubMed Central Google Scholar
Wang Q, Chen B, Sheng D, Yang J, Fu S, Wang J, et al. Multiomics analysis reveals aberrant metabolism and immunity linked gut microbiota with insomnia. Microbiology Spectrum. 2022;10(5):e0099822.
Wang Z, Wang Z, Lu T, Chen W, Yan W, Yuan K, et al. The microbiota-gut-brain axis in sleep disorders. Sleep Med Rev. 2022;65:101691.
Article CAS PubMed Google Scholar
Golubnitschaja O, Kubatka P, Mazurakova A, Samec M, Alajati A, Giordano FA, Costigliola V, Ellinger J, Ritter M. Systemic effects reflected in specific biomarker patterns are instrumental for the paradigm change in prostate cancer management: A strategic paper. Cancers (Basel). 2022;14(3):675. https://doi.org/10.3390/cancers14030675
Gilbert JA, Quinn RA, Debelius J, Xu ZZ, Morton J, Garg N, et al. Microbiome-wide association studies link dynamic microbial consortia to disease. Nature. 2016;535(7610):94–103.
Article CAS PubMed Google Scholar
Sonnenburg JL, Bäckhed F. Diet-microbiota interactions as moderators of human metabolism. Nature. 2016;535(7610):56–64.
Article CAS PubMed PubMed Central Google Scholar
Lynch SV, Pedersen O. The human intestinal microbiome in health and disease. N Engl J Med. 2016;375(24):2369–79.
Article CAS PubMed Google Scholar
Feng W, Yang Z, Liu Y, Chen R, Song Z, Pan G, et al. Gut microbiota: a new target of traditional Chinese medicine for insomnia. Biomed Pharmacother. 2023;160:114344.
Article CAS PubMed Google Scholar
Kang Y, Kang X, Cai Y. The gut microbiome as a target for adjuvant therapy in insomnia disorder. Clin Res Hepatol Gastroenterol. 2022;46(1):101834.
Article CAS PubMed Google Scholar
Tang M, Song X, Zhong W, Xie Y, Liu Y, Zhang X. Dietary fiber ameliorates sleep disturbance connected to the gut-brain axis. Food Funct. 2022;13(23):12011–20.
Article CAS PubMed Google Scholar
Boyko N, Costigliola V, Golubnitschaja O. Microbiome in the framework of predictive, preventive and personalised medicine. In: Boyko N, Golubnitschaja O, editors. Microbiome in 3P medicine strategies: the first exploitation guide. Cham: Springer International Publishing; 2023. p. 1–8.
Neroni B, Evangelisti M, Radocchia G, Di Nardo G, Pantanella F, Villa MP, et al. Relationship between sleep disorders and gut dysbiosis: what affects what? Sleep Med. 2021;87:1–7.
Sen P, Molinero-Perez A, O’Riordan KJ, McCafferty CP, O’Halloran KD, Cryan JF. Microbiota and sleep: awakening the gut feeling. Trends Mol Med. 2021;27(10):935–45.
Article CAS PubMed Google Scholar
Goodrich JK, Davenport ER, Clark AG, Ley RE. The relationship between the human genome and microbiome comes into view. Annu Rev Genet. 2017;51:413–33.
Article CAS PubMed PubMed Central Google Scholar
Emdin CA, Khera AV, Kathiresan S. Mendelian randomization. JAMA. 2017;318(19):1925–6.
Zhuang Z, Yang R, Wang W, Qi L, Huang T. Associations between gut microbiota and Alzheimer’s disease, major depressive disorder, and schizophrenia. J Neuroinflammation. 2020;17(1):288.
Article CAS PubMed PubMed Central Google Scholar
Kurilshikov A, Medina-Gomez C, Bacigalupe R, Radjabzadeh D, Wang J, Demirkan A, et al. Large-scale association analyses identify host factors influencing human gut microbiome composition. Nat Genet. 2021;53(2):156–65.
Article CAS PubMed PubMed Central Google Scholar
Jansen PR, Watanabe K, Stringer S, Skene N, Bryois J, Hammerschlag AR, et al. Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways. Nat Genet. 2019;51(3):394–403.
Article CAS PubMed Google Scholar
Ahola-Olli AV, Würtz P, Havulinna AS, Aalto K, Pitkänen N, Lehtimäki T, et al. Genome-wide association study identifies 27 loci influencing concentrations of circulating cytokines and growth factors. Am J Hum Genet. 2017;100(1):40–50.
Article CAS PubMed Google Scholar
Said S, Pazoki R, Karhunen V, Võsa U, Ligthart S, Bodinier B, et al. Genetic analysis of over half a million people characterises C-reactive protein loci. Nat Commun. 2022;13(1):2198.
Article CAS PubMed PubMed Central Google Scholar
MiBioGen consortium. MiBioGen 2021 [Available from: https://mibiogen.gcc.rug.nl/.
Hammerschlag AR, Stringer S, de Leeuw CA, Sniekers S, Taskesen E, Watanabe K, et al. Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits. Nat Genet. 2017;49(11):1584–92.
Article CAS PubMed PubMed Central Google Scholar
Sanna S, van Zuydam NR, Mahajan A, Kurilshikov A, Vich Vila A, Võsa U, et al. Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases. Nat Genet. 2019;51(4):600–5.
Article CAS PubMed PubMed Central Google Scholar
Burgess S, Butterworth A, Thompson SG. Mendelian randomization analysis with multiple genetic variants using summarized data. Genet Epidemiol. 2013;37(7):658–65.
Article PubMed PubMed Central Google Scholar
Burgess S, Dudbridge F, Thompson SG. Combining information on multiple instrumental variables in Mendelian randomization: comparison of allele score and summarized data methods. Stat Med. 2016;35(11):1880–906.
Hartwig FP, Davey Smith G, Bowden J. Robust inference in summary data Mendelian randomization via the zero modal pleiotropy assumption. Int J Epidemiol. 2017;46(6):1985–98.
Article PubMed PubMed Central Google Scholar
Bowden J, Davey Smith G, Haycock PC, Burgess S. Consistent estimation in Mendelian randomization with some invalid instruments using a weighted median estimator. Genet Epidemiol. 2016;40(4):304–14.
Article PubMed PubMed Central Google Scholar
Storey JD, Tibshirani R. Statistical significance for genomewide studies. Proc Natl Acad Sci USA. 2003;100(16):9440–5.
Article CAS PubMed PubMed Central Google Scholar
Carter AR, Sanderson E, Hammerton G, Richmond RC, Davey Smith G, Heron J, et al. Mendelian randomisation for mediation analysis: current methods and challenges for implementation. Eur J
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