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Unleashing the potential of exercise: conquering cardiovascular disease by targeting inflammasome activation
Unleashing the potential of exercise: conquering cardiovascular disease by targeting inflammasome activation
The development of cardiovascular diseases (CVD) is intricate and has many contributing factors, with inflammation being a...
Inhibition RIP1 prevents acute liver failure by suppressing hepatic apoptosis and attenuating the secretion of TNF-α from macrophages
Inhibition RIP1 prevents acute liver failure by suppressing hepatic apoptosis and attenuating the secretion of TNF-α from macrophages
Acute liver failure (ALF) is a rapidly progressing clinical syndrome with a high mortality rate and limited treatment opti...
Ulinastatin inhibits macrophage M1 polarization to improve acute pancreatitis-associated intestinal barrier dysfunction by promoting Nrf2 signaling pathway activation
Ulinastatin inhibits macrophage M1 polarization to improve acute pancreatitis-associated intestinal barrier dysfunction by promoting Nrf2 signaling pathway activation
Intestinal barrier dysfunction plays a significant role in the development of pancreatic necrosis and multiple organ failu...
A review on computer-aided diagnostic system to classify the disorders of the gastrointestinal tract
A review on computer-aided diagnostic system to classify the disorders of the gastrointestinal tract
Various diseases, such as colon cancer, gastric cancer, celiac, and bleeding, pose a significant risk to the gastrointesti...
Gamma-tocopherol vitamin E enhances the cytotoxicity of p-cresyl sulfate to renal tubular cells
Gamma-tocopherol vitamin E enhances the cytotoxicity of p-cresyl sulfate to renal tubular cells
The protein-bound uremic toxins p-cresyl sulfate (PCS) and indoxyl sulfate (IS) are commonly found at elevated levels in p...
ABO blood type is not a risk factor of outcome in aneurysmal subarachnoid hemorrhage patients
ABO blood type is not a risk factor of outcome in aneurysmal subarachnoid hemorrhage patients
The association between ABO blood types and outcome of aneurysm subarachnoid hemorrhage (aSAH) has not reached a conclusio...
Analysis of coinfections in patients with hematologic malignancies and COVID-19 by next-generation sequencing of bronchoalveolar lavage fluid
Analysis of coinfections in patients with hematologic malignancies and COVID-19 by next-generation sequencing of bronchoalveolar lavage fluid
Coinfections in patients with coronavirus disease 2019 (COVID-19) affect patient prognosis. Patients with hematologic mali...
Correlation between lipid accumulation product and epigenetic age acceleration in American adults: a cross-sectional analysis using NHANES data
Correlation between lipid accumulation product and epigenetic age acceleration in American adults: a cross-sectional analysis using NHANES data
The risks of obesity and epigenetic age acceleration (EAA) have drawn widespread attention. Lipid accumulation product (LA...
Effects of staphylococcal enterotoxin and fungal sensitization on clinical outcomes of asthma
Effects of staphylococcal enterotoxin and fungal sensitization on clinical outcomes of asthma
Staphylococcal enterotoxin and fungal sensitization can influence asthma severity; however, the effects on the clinical ou...
Pulsed radiofrequency alleviates neuropathic pain by upregulating MG53 to inhibit microglial activation
Pulsed radiofrequency alleviates neuropathic pain by upregulating MG53 to inhibit microglial activation
Patients with neuropathic pain (NP) have significantly lower quality of life. Because the pathophysiology of NP is not ful...
Dysregulated cholesterol regulatory genes in hepatocellular carcinoma
Dysregulated cholesterol regulatory genes in hepatocellular carcinoma
Cholesterol is an indispensable component in mammalian cells, and cholesterol metabolism performs important roles in vario...
Causal associations between genetically determined common psychiatric disorders and the risk of falls: evidence from Mendelian randomization
Causal associations between genetically determined common psychiatric disorders and the risk of falls: evidence from Mendelian randomization
The causal associations between psychiatric disorders and falls risk remains uncertain. Consequently, this study aimed to ...
Mesenchymal stem cells-derived exosomes: novel carriers for nanoparticle to combat cancer
Mesenchymal stem cells-derived exosomes: novel carriers for nanoparticle to combat cancer
The advancement in novel cancer therapeutics brought a platform combining the properties of exosomes with nanoparticles to...
Differentiation between cerebral alveolar echinococcosis and brain metastases with radiomics combined machine learning approach
Differentiation between cerebral alveolar echinococcosis and brain metastases with radiomics combined machine learning approach
Cerebral alveolar echinococcosis (CAE) and brain metastases (BM) share similar in locations and imaging appearance. Howeve...
Systemic immune-inflammation index (SII) and the risk of all-cause, cardiovascular, and cardio-cerebrovascular mortality in the general population
Systemic immune-inflammation index (SII) and the risk of all-cause, cardiovascular, and cardio-cerebrovascular mortality in the general population
An elevated systemic immune-inflammation index (SII) is associated with higher mortality in patients with coronary artery ...
Comparison of different internal fixation models in ankle arthrodesis using 3D finite-element analysis
Comparison of different internal fixation models in ankle arthrodesis using 3D finite-element analysis
The purpose of this study is to use three-dimensional finite-element analysis to better understand the biomechanical featu...
Association between statin use on delirium and 30-day mortality in patients with chronic obstructive pulmonary disease in the intensive care unit
Association between statin use on delirium and 30-day mortality in patients with chronic obstructive pulmonary disease in the intensive care unit
Delirium occurs frequently in patients with chronic obstructive pulmonary disease in the intensive care unit. Effective pr...
Initiation and rapid titration of methadone and slow-release oral morphine (SROM) in an acute care, inpatient setting: a case series
Initiation and rapid titration of methadone and slow-release oral morphine (SROM) in an acute care, inpatient setting: a case series
Methadone titration in an outpatient setting typically involves initiation with subtherapeutic doses with slow titration t...
Treatment of brainstem and fourth ventricle lesions by the full neuroendoscopic telovelar approach
Treatment of brainstem and fourth ventricle lesions by the full neuroendoscopic telovelar approach
To explore the surgical techniques, advantages, and disadvantages of neuroendoscopic telovelar approach in the treatment o...
Disulfidptosis-related signatures for prognostic and immunotherapy reactivity evaluation in hepatocellular carcinoma
Disulfidptosis-related signatures for prognostic and immunotherapy reactivity evaluation in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most common cancers in the world and a nonnegligible health concern ...
The value of the cinematic volume rendering technique: magnetic resonance imaging in diagnosing tumors associated with the brachial plexus
The value of the cinematic volume rendering technique: magnetic resonance imaging in diagnosing tumors associated with the brachial plexus
To examine the diagnostic advantages and clinical application value of the cinematic volume rendering technique (cVRT) whe...
SNAP25 is a potential target for early stage Alzheimer’s disease and Parkinson’s disease
SNAP25 is a potential target for early stage Alzheimer’s disease and Parkinson’s disease
Alzheimer’s disease (AD) and Parkinson’s disease (PD), two common irreversible neurodegenerative diseases, sha...
Characteristics and outcomes of patients hospitalized for infection with influenza, SARS-CoV-2 or respiratory syncytial virus in the season 2022/2023 in a large German primary care centre
Characteristics and outcomes of patients hospitalized for infection with influenza, SARS-CoV-2 or respiratory syncytial virus in the season 2022/2023 in a large German primary care centre
In 2022/2023, Influenza A and Respiratory Syncytial Virus (RSV) reappeared in hospitalized patients, which was in parallel...
Functional independence, frailty and perceived quality of life in patients who developed delirium during ICU stay: a prospective cohort study
Functional independence, frailty and perceived quality of life in patients who developed delirium during ICU stay: a prospective cohort study
Survivors of critical illness are frequently left with a long-lasting disability. We hypothesised that patients who develo...
Severity of oxidative stress as a hallmark in COVID-19 patients
Severity of oxidative stress as a hallmark in COVID-19 patients
Understanding the mechanisms and identifying effective treatments for the COVID-19 outbreak are imperative. Therefore, thi...
Performance of severity indices for admission and mortality of trauma patients in the intensive care unit: a retrospective cohort study
Performance of severity indices for admission and mortality of trauma patients in the intensive care unit: a retrospective cohort study
Little is known about the performance of severity indices for indicating intensive care and predicting mortality in the In...
A J-shaped relationship between body mass index and the risk of elevated liver stiffness: a cross-sectional study
A J-shaped relationship between body mass index and the risk of elevated liver stiffness: a cross-sectional study
Liver stiffness (LS) is regarded as an indicator of the stages of liver fibrosis and liver cirrhosis. Numerous studies hav...
Adhatoda vasica and Tinospora cordifolia extracts ameliorate clinical and molecular markers in mild COVID-19 patients: a randomized open-label three-armed study
Adhatoda vasica and Tinospora cordifolia extracts ameliorate clinical and molecular markers in mild COVID-19 patients: a randomized open-label three-armed study
SARS-CoV-2 infections caused mild-to-moderate illness. However, a sizable portion of infected people experience a rapid pr...
Validation of non-invasive indicators in the screening of metabolic dysfunction-associated fatty liver disease: a cross-sectional study among Uighurs in rural Xinjiang
Validation of non-invasive indicators in the screening of metabolic dysfunction-associated fatty liver disease: a cross-sectional study among Uighurs in rural Xinjiang
Metabolic dysfunction-associated fatty liver disease (MAFLD) is the most common chronic liver disease in China. Our study ...
Role of advanced glycation end products in diabetic vascular injury: molecular mechanisms and therapeutic perspectives
Role of advanced glycation end products in diabetic vascular injury: molecular mechanisms and therapeutic perspectives
In diabetic metabolic disorders, advanced glycation end products (AGEs) contribute significantly to the development of car...
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