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Using artificial intelligence to prioritize pathology samples: report of a test drive
Using artificial intelligence to prioritize pathology samples: report of a test drive
The digital transformation of pathology, through automation and computational tools, addresses current challenges in the f...
High expression of RHOF is an effective diagnostic marker and a potential prognostic indicator for primary mediastinal large B-cell lymphoma
High expression of RHOF is an effective diagnostic marker and a potential prognostic indicator for primary mediastinal large B-cell lymphoma
Due to the overlap of histological and molecular features of primary mediastinal large B-cell lymphoma (PMBL) with other l...
Uterine sarcoma with KAT6B/A::KANSL1 fusion: a molecular and clinicopathological study on 9 cases
Uterine sarcoma with KAT6B/A::KANSL1 fusion: a molecular and clinicopathological study on 9 cases
Uterine sarcomas with KAT6B/A::KANSL1 fusion represent a new entity characterized by bland morphology, commonly with hybri...
Breaking barriers in pathology: bridging gaps in multidisciplinary collaboration
Breaking barriers in pathology: bridging gaps in multidisciplinary collaboration
Pathology is a unique medical specialty, often misperceived as being limited to disease classification based on morphology...
Tenosynovitis with psammomatous calcifications: Series of 18 cases and review of the literature emphasizing a common source of expert consultation and updated differential diagnosis
Tenosynovitis with psammomatous calcifications: Series of 18 cases and review of the literature emphasizing a common source of expert consultation and updated differential diagnosis
Tenosynovitis with psammomatous calcifications (TPC) is a rare, benign condition currently regarded as a pseudotumor possi...
YAP1::KMT2A-rearranged sarcomas harbor a unique methylation profile and are distinct from sclerosing epithelioid fibrosarcoma and low-grade fibromyxoid sarcoma
YAP1::KMT2A-rearranged sarcomas harbor a unique methylation profile and are distinct from sclerosing epithelioid fibrosarcoma and low-grade fibromyxoid sarcoma
Sclerosing epithelioid fibrosarcoma (SEF) was originally described as a peculiar variant of fibrosarcoma in 1995. Subseque...
Polarised light scanner for digital pathology
Polarised light scanner for digital pathology
Digital pathology is rapidly transforming diagnostic pathology by allowing remote work and integration of artificial intel...
High interobserver variability of PTEN immunohistochemistry defining PTEN status in low- to intermediate-risk prostate cancer: results of the first German ring trial
High interobserver variability of PTEN immunohistochemistry defining PTEN status in low- to intermediate-risk prostate cancer: results of the first German ring trial
The prognostication of individual disease trajectory and selection of optimal therapy in patients with localized, low-grad...
ERBB2/ERBB3-mutated S100/SOX10-positive uterine sarcoma: something new
ERBB2/ERBB3-mutated S100/SOX10-positive uterine sarcoma: something new
A distinctive subset of uterine mesenchymal tumors display recurrent genetic fusions involving receptor tyrosine kinases, ...
Diagnostic relevance of p53 and Rb status in neuroendocrine tumors G3 from different organs: an immunohistochemical study of 465 high-grade neuroendocrine neoplasms
Diagnostic relevance of p53 and Rb status in neuroendocrine tumors G3 from different organs: an immunohistochemical study of 465 high-grade neuroendocrine neoplasms
The double inactivation of TP53 and RB1 is considered typical of neuroendocrine carcinomas (NECs) but is assumed to be rar...
Julius Hirschberg und die Geschichte der Augenheilkunde
Julius Hirschberg und die Geschichte der Augenheilkunde
Die Werke von Julius Hirschberg (1843–1925), insbesondere seine „Geschichte der Augenheilkunde“ sind bis...
Next-generation sequencing in the molecular classification of endometrial carcinomas: Experience with 270 cases suggesting a potentially more aggressive clinical behavior of multiple classifier endometrial carcinomas
Next-generation sequencing in the molecular classification of endometrial carcinomas: Experience with 270 cases suggesting a potentially more aggressive clinical behavior of multiple classifier endometrial carcinomas
Molecular classification of endometrial carcinomas (EC) divides these neoplasms into four distinct subgroups based on thei...
Prevalence and interpretation of AFF immunostain of DEK::AFF2 fusion-associated papillary squamous cell carcinoma in a retrospective cohort of recurrent sinonasal papillomas
Prevalence and interpretation of AFF immunostain of DEK::AFF2 fusion-associated papillary squamous cell carcinoma in a retrospective cohort of recurrent sinonasal papillomas
DEK::AFF2 fusion-associated papillary squamous cell carcinoma is a novel entity characterized by its unique translocation ...
SATB2, CKAE1/AE3, and synaptophysin as a sensitive immunohistochemical panel for the detection of lymph node metastases of Merkel cell carcinoma
SATB2, CKAE1/AE3, and synaptophysin as a sensitive immunohistochemical panel for the detection of lymph node metastases of Merkel cell carcinoma
Histopathological evaluation of lymph nodes in Merkel cell carcinoma has become crucial in progression estimation and trea...
Correction to: HER2 copy number determination in breast cancer using the highly sensitive droplet digital PCR method
Correction to: HER2 copy number determination in breast cancer using the highly sensitive droplet digital PCR method
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
Postponing evolution: why are we choosing to ignore the need for a digital transformation in pathology?
Postponing evolution: why are we choosing to ignore the need for a digital transformation in pathology?
For some years now, practical evidence on the benefits of using whole slide images (W...
Letter to the editor on Donzel M et al. “Androgenetic/biparental mosaicism in a diploid mole-like conceptus: report of a case with triple paternal contribution”
Letter to the editor on Donzel M et al. “Androgenetic/biparental mosaicism in a diploid mole-like conceptus: report of a case with triple paternal contribution”
Donzel M, Gaillot-Durand L, Joubert M, Aziza J, Beneteau C, Mauduit C, Ploteau S, Hajri T, Bolze PA, Massardier J, Devouas...
„Rasse“ als globaler Datenstrom: Die Hamburger Anthropologie des 20. Jahrhunderts als Ausgangspunkt einer Datengeschichte der Rassifizierung
„Rasse“ als globaler Datenstrom: Die Hamburger Anthropologie des 20. Jahrhunderts als Ausgangspunkt einer Datengeschichte der Rassifizierung
Dieser Aufsatz zeigt anhand der Hamburger Anthropologie des 20. Jahrhunderts, wie historisch spezifische Aufschre...
Immunohistochemical markers as predictors of prognosis in multifocal prostate cancer
Immunohistochemical markers as predictors of prognosis in multifocal prostate cancer
The impact of tumor focality on prostate cancer (PCa) prognosis has been addressed in several studies with conflicting res...
Molecular pathology in breast disease: diagnostic, prognostic, and therapeutic tools
Molecular pathology in breast disease: diagnostic, prognostic, and therapeutic tools
Molecular testing in breast cancer gained increasing attention and importance as specific molecular results can tailor not...
HER2 copy number determination in breast cancer using the highly sensitive droplet digital PCR method
HER2 copy number determination in breast cancer using the highly sensitive droplet digital PCR method
Human epidermal growth factor receptor 2 (HER)-positive breast cancer (BC) is characterized by an aggressive clinical cour...
The practical utility of AI-assisted molecular profiling in the diagnosis and management of cancer of unknown primary: an updated review
The practical utility of AI-assisted molecular profiling in the diagnosis and management of cancer of unknown primary: an updated review
Cancer of unknown primary (CUP) presents a complex diagnostic challenge, characterized by metastatic tumors of unknown tis...
Genomic alterations and diagnosis of renal cancer
Genomic alterations and diagnosis of renal cancer
The application of molecular profiling has made substantial impact on the classification of urogenital tumors. Therefore, ...
Pathologic approach to Neonatal cholestasis with a simple scoring system for biliary atresia
Pathologic approach to Neonatal cholestasis with a simple scoring system for biliary atresia
A liver biopsy is essential for the diagnostic workup of persistent neonatal cholestasis (NC). The differential diagnosis ...
Molecular pathology as basis for timely cancer diagnosis and therapy
Molecular pathology as basis for timely cancer diagnosis and therapy
Precision and personalized therapeutics have witnessed significant advancements in technology, revolutionizing the capabil...
T cell phenotype and lack of eosinophilia are not uncommon in extramedullary myeloid/lymphoid neoplasms with ETV6::FLT3 fusion: a case report and review of the literature
T cell phenotype and lack of eosinophilia are not uncommon in extramedullary myeloid/lymphoid neoplasms with ETV6::FLT3 fusion: a case report and review of the literature
In the 2022, WHO and ICC classifications, myeloid/lymphoid neoplasms with eosinophilia (M/LN-eo) and tyrosine kinase gene ...
Molecular diagnostics tailoring personalized cancer therapy—an oncologist’s view
Molecular diagnostics tailoring personalized cancer therapy—an oncologist’s view
Medical oncology is rapidly evolving with the implementation of personalized, targeted therapies. Advances in molecular di...
Adenoid cystic carcinoma metastatic to the kidney: a series of 10 patients emphasizing unilateral presentation and long time interval from primary diagnosis
Adenoid cystic carcinoma metastatic to the kidney: a series of 10 patients emphasizing unilateral presentation and long time interval from primary diagnosis
Adenoid cystic carcinoma (AdCC) metastasis to kidney is rare. We identified 10 patients with metastatic AdCC in multi-inst...
Clinicopathological differences in focal segmental glomerulosclerosis depending on the accompanying pathophysiological conditions in renal allografts
Clinicopathological differences in focal segmental glomerulosclerosis depending on the accompanying pathophysiological conditions in renal allografts
Primary focal segmental glomerulosclerosis (FSGS) is thought to be caused by circulating factors leading to podocytopathy,...
Correction to: Immunoglobulin light chain transcript detection by ultrasensitive RNA in situ hybridization for B-cell lymphoma diagnosis
Correction to: Immunoglobulin light chain transcript detection by ultrasensitive RNA in situ hybridization for B-cell lymphoma diagnosis
Pathology Unit, Department of Molecular and Translational Medicine-DMMT, University of Brescia, Brescia, ItalyLuisa Lorenz...
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