SCI Abstract

search
FDA-approved disulfiram as a novel treatment for aggressive leukemia
FDA-approved disulfiram as a novel treatment for aggressive leukemia
Acute leukemia continues to be a major cause of death from disease worldwide and current chemotherapeutic agents are assoc...
Systemic and local effect of oxidative stress on recurrent aphthous stomatitis: systematic review
Systemic and local effect of oxidative stress on recurrent aphthous stomatitis: systematic review
Recurrent aphthous stomatitis (RAS) is a chronic and recurrent inflammatory disease of the mouth. It is characterised by t...
Altered expression of Sialyl Lewis X in experimental models of Parkinson’s disease
Altered expression of Sialyl Lewis X in experimental models of Parkinson’s disease
The mechanisms underlying neurodegeneration in Parkinson’s disease (PD) are still not fully understood. Glycosylatio...
Spinal cord abnormal autophagy and mitochondria energy metabolism are modified by swim training in SOD1-G93A mice
Spinal cord abnormal autophagy and mitochondria energy metabolism are modified by swim training in SOD1-G93A mice
Amyotrophic lateral sclerosis (ALS) may result from the dysfunctions of various mechanisms such as protein accumulation, m...
Etiopathogenesis of medication-related osteonecrosis of the jaws: a review
Etiopathogenesis of medication-related osteonecrosis of the jaws: a review
This study compiles the main hypotheses involved in the etiopathogenesis of medication-related osteonecrosis of the jaw (M...
Traumatic brain injury-induced disruption of the circadian clock
Traumatic brain injury-induced disruption of the circadian clock
Disturbances in the circadian rhythm have been reported in patients following traumatic brain injury (TBI). However, the r...
High expression of BCAT1 sensitizes AML cells to PARP inhibitor by suppressing DNA damage response
High expression of BCAT1 sensitizes AML cells to PARP inhibitor by suppressing DNA damage response
Previous evidence has confirmed that branched-chain aminotransferase-1 (BCAT1), a key enzyme governing branched-chain amin...
Circular RNAs: Regulators of endothelial cell dysfunction in atherosclerosis
Circular RNAs: Regulators of endothelial cell dysfunction in atherosclerosis
Endothelial cell (EC) dysfunction is associated with atherosclerosis. Circular RNAs (circRNAs) are covalently closed loops...
PRKAA2, MTOR, and TFEB in the regulation of lysosomal damage response and autophagy
PRKAA2, MTOR, and TFEB in the regulation of lysosomal damage response and autophagy
Lysosomes function as critical signaling hubs that govern essential enzyme complexes. LGALS proteins (LGALS3, LGALS8, and ...
Ubiquitination and deubiquitination in the regulation of N6-methyladenosine functional molecules
Ubiquitination and deubiquitination in the regulation of N6-methyladenosine functional molecules
N6 methyladenosine (m6A) is the most prevalent RNA epigenetic modification, regulated by methyltransferases and demethyltr...
DSPE-PEG2000-methotrexate nanoparticles encapsulating phenobarbital sodium kill cancer cells by inducing pyroptosis
DSPE-PEG2000-methotrexate nanoparticles encapsulating phenobarbital sodium kill cancer cells by inducing pyroptosis
Cancer is a life-threatening disease worldwide. Nanomedicine and nanodelivery systems are recently developed scientific fi...
TAT-W61 peptide attenuates neuronal injury through blocking the binding of S100b to the V-domain of Rage during ischemic stroke
TAT-W61 peptide attenuates neuronal injury through blocking the binding of S100b to the V-domain of Rage during ischemic stroke
Ischemic stroke is a devastative nervous system disease associated with high mortality and morbidity rates. Unfortunately,...
CTHRC1 promotes colorectal cancer progression by recruiting tumor-associated macrophages via up-regulation of CCL15
CTHRC1 promotes colorectal cancer progression by recruiting tumor-associated macrophages via up-regulation of CCL15
Tumor-associated macrophages (TAMs) represent a key factor in the tumor immune microenvironment (TME), exerting significan...
A gene therapy targeting medium-chain acyl-CoA dehydrogenase (MCAD) did not protect against diabetes-induced cardiac pathology
A gene therapy targeting medium-chain acyl-CoA dehydrogenase (MCAD) did not protect against diabetes-induced cardiac pathology
Diabetic cardiomyopathy describes heart disease in patients with diabetes who have no other cardiac conditions but have a ...
The role of CD146 in renal disease: from experimental nephropathy to clinics
The role of CD146 in renal disease: from experimental nephropathy to clinics
Vascular endothelial dysfunction is a major risk factor in the development of renal diseases. Recent studies pointed out a...
IL-23 contributes to Particulate Matter induced allergic asthma in the early life of mice and promotes asthma susceptibility
IL-23 contributes to Particulate Matter induced allergic asthma in the early life of mice and promotes asthma susceptibility
Air pollutant exposure leads to and exacerbates respiratory diseases. Particulate Matter (PM) is a major deleterious facto...
Sphingolipids: drivers of cardiac fibrosis and atrial fibrillation
Sphingolipids: drivers of cardiac fibrosis and atrial fibrillation
Sphingolipids (SLs) are vital constituents of the plasma membrane of animal cells and concurrently regulate numerous cellu...
Effects of different amosite preparations on macrophages, lung damages, and autoimmunity
Effects of different amosite preparations on macrophages, lung damages, and autoimmunity
The underlying mechanisms of asbestos-related autoimmunity are poorly understood. As the size, surface reactivity, and fre...
Comparing plasma and skin imprint metabolic profiles in COVID-19 diagnosis and severity assessment
Comparing plasma and skin imprint metabolic profiles in COVID-19 diagnosis and severity assessment
As SARS-CoV-2 continues to produce new variants, the demand for diagnostics and a better understanding of COVID-19 remain ...
Progress in diagnosis and treatment of Leber’s hereditary optic neuropathy
Progress in diagnosis and treatment of Leber’s hereditary optic neuropathy
Leber’s hereditary optic neuropathy (LHON) is a mitochondrial genetic disease with central vision loss as the main s...
Correction to: Downregulation of microRNA-193a-3p is involved in invertebral disc degeneration by targeting MMP14
Correction to: Downregulation of microRNA-193a-3p is involved in invertebral disc degeneration by targeting MMP14
The authors were notified of error that occurred in Fig. 5E of the above paper. The abscissa axis of Fig. 5E should be the...
Identifying survival of pan-cancer patients under immunotherapy using genomic mutation signature with large sample cohorts
Identifying survival of pan-cancer patients under immunotherapy using genomic mutation signature with large sample cohorts
Although immune checkpoint inhibitors have led to durable clinical response in multiple cancers, only a small proportion o...
Correction to: Microdevices for cancer stem cell culture as a predictive chemotherapeutic response platform
Correction to: Microdevices for cancer stem cell culture as a predictive chemotherapeutic response platform
Facultad de Ciencias Médicas, Instituto de Oncología “Ángel H. Roffo”, Área de Investigación, Universidad de Buenos Aires,...