Stockwell BR (2022) Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications. Cell 185:2401–2421

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yang WS, Stockwell BR (2016) Ferroptosis: death by lipid peroxidation. Trends Cell Biol 26:165–176

Article  CAS  PubMed  Google Scholar 

Li J, Cao F, Yin HL et al (2020) Ferroptosis: past, present and future. Cell Death Dis 11:88

Article  PubMed  PubMed Central  Google Scholar 

Yang WS, SriRamaratnam R, Welsch ME et al (2014) Regulation of ferroptotic cancer cell death by GPX4. Cell 156:317–331

Article  CAS  PubMed  PubMed Central  Google Scholar 

Andrews NC, Schmidt PJ (2007) Iron homeostasis. Annu Rev Physiol 69:69–85

Article  CAS  PubMed  Google Scholar 

Mao C, Liu X, Zhang Y et al (2021) DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer. Nature 593:586–590

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jiang X, Stockwell BR, Conrad M (2021) Ferroptosis: mechanisms, biology and role in disease. Nat Rev Mol Cell Biol 22:266–282

Article  PubMed  PubMed Central  Google Scholar 

Yang W, Mu B, You J et al (2022) Non-classical ferroptosis inhibition by a small molecule targeting PHB2. Nat Commun 13:7473

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sun LL, Linghu DL, Hung MC (2021) Ferroptosis: a promising target for cancer immunotherapy. Am J Cancer Res 11:5856–5863

CAS  PubMed  PubMed Central  Google Scholar 

Wang X, Zhou Y, Min J et al (2023) Zooming in and out of ferroptosis in human disease. Front Med 17:173–206

Article  CAS  PubMed  Google Scholar 

FriedmannAngeli JP, Schneider M, Proneth B et al (2014) Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice. Nat Cell Biol 16:1180–1191

Article  CAS  Google Scholar 

Xu S, Min J, Wang F (2021) Ferroptosis: an emerging player in immune cells. Science bulletin 66:2257–2260

Article  CAS  PubMed  Google Scholar 

Fang X, Wang H, Han D et al (2019) Ferroptosis as a target for protection against cardiomyopathy. Proc Natl Acad Sci USA 116:2672–2680

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fang X, Zhang J, Li Y et al (2023) Malic enzyme 1 as a novel anti-ferroptotic regulator in hepatic ischemia/reperfusion injury. Adv Sci (Weinheim, Baden-Wurttemberg, Germany) 10:2205436

CAS  Google Scholar 

Stockwell BR, FriedmannAngeli JP, Bayir H et al (2017) Ferroptosis: a regulated cell death nexus linking metabolism. Redox Biol Dis Cell 171:273–285

CAS  Google Scholar 

Wang Y, Wu S, Li Q et al (2023) Pharmacological inhibition of ferroptosis as a therapeutic target for neurodegenerative diseases and strokes. Adv Sci (Weinheim, Baden-Wurttemberg, Germany) 10:e2300325

Google Scholar 

Du Y, Guo Z (2022) Recent progress in ferroptosis: inducers and inhibitors. Cell Death Discov 8:501

Article  CAS  PubMed  PubMed Central  Google Scholar 

Peng X, Tan Q, Zhou H et al (2021) Discovery of phloroglucinols from Hypericum japonicum as ferroptosis inhibitors. Fitoterapia 153:104984

Article  CAS  PubMed  Google Scholar 

Van Coillie S, Van San E, Goetschalckx I et al (2022) Targeting ferroptosis protects against experimental (multi)organ dysfunction and death. Nat Commun 13:1046

Article  PubMed  PubMed Central  Google Scholar 

Guan Q, Zhou LL, Dong YB (2021) Ferroptosis in cancer therapeutics: a materials chemistry perspective. J Mater Chem B 9:8906–8936

Article  CAS  PubMed  Google Scholar 

Wickline SA, Neubauer AM, Winter PM et al (2007) Molecular imaging and therapy of atherosclerosis with targeted nanoparticles. J Magnet Reson Imag : JMRI 25:667–680

Article  Google Scholar 

Liu Z, Jiao Y, Wang Y et al (2008) Polysaccharides-based nanoparticles as drug delivery systems. Adv Drug Deliv Rev 60:1650–1662

Article  CAS  PubMed  Google Scholar 

Kim YG, Lee Y, Lee N et al (2023) Ceria-based therapeutic antioxidants for biomedical applications. Adv Mater (Deerfield Beach, Fla) 2023:e2210819

Google Scholar 

Korsvik C, Patil S, Seal S et al (2007) Superoxide dismutase mimetic properties exhibited by vacancy engineered ceria nanoparticles, Chemical communications. England), Cambridge, pp 1056–1058

Google Scholar 

Yang J, Bai Y, Shen S et al (2023) An oral nano-antioxidant for targeted treatment of inflammatory bowel disease by regulating macrophage polarization and inhibiting ferroptosis of intestinal cells. Chem Eng J 465:142940

Article  CAS  Google Scholar 

Luo L-J, Nguyen DD, Lai J-Y (2020) Dually functional hollow ceria nanoparticle platform for intraocular drug delivery: a push beyond the limits of static and dynamic ocular barriers toward glaucoma therapy. Biomaterials 243:119961

Article  CAS  PubMed  Google Scholar 

He L, Huang G, Liu H et al (2020) Highly bioactive zeolitic imidazolate framework-8 capped nanotherapeutics for efficient reversal of reperfusion-induced injury in ischemic stroke. Sci Adv 6:9751

Article  Google Scholar 

Zhou L, Tang S, Li F et al (2022) Ceria nanoparticles prophylactic used for renal ischemia-reperfusion injury treatment by attenuating oxidative stress and inflammatory response. Biomaterials 287:121686

Article  CAS  PubMed  Google Scholar 

Zhao S, Li Y, Liu Q et al (2020) An orally administered CeO2@montmorillonite nanozyme targets inflammation for inflammatory bowel disease therapy. Adv Func Mater 30:2004692

Article  CAS  Google Scholar 

Kim CK, Kim T, Choi I-Y et al (2012) Ceria nanoparticles that can protect against ischemic stroke. Angew Chem Int Ed 51:11039–11043

Article  CAS  Google Scholar 

Muhammad F, Huang F, Cheng Y, Wei H et al (2022) Nanoceria as an electron reservoir: spontaneous deposition of metal nanoparticles on oxides and their anti-inflammatory activities. ACS Nano 16:20567–20576

Article  CAS  PubMed  Google Scholar 

Zhang Y, Liu S, Peng J et al (2023) Biomimetic nanozymes suppressed ferroptosis to ameliorate doxorubicin-induced cardiotoxicity via synergetic effect of antioxidant stress and GPX4 restoration. Nutrients 15:1090

Article  CAS  PubMed  PubMed Central  Google Scholar 

Feng Y, Luo X, Li Z et al (2023) A ferroptosis-targeting ceria anchored halloysite as orally drug delivery system for radiation colitis therapy. Nat Commun 14:5083

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yang Y, Li M, Pan G et al (2023) Multiple stimuli-responsive nanozyme-based cryogels with controlled no release as self-adaptive wound dressing for infected wound healing. Adv Func Mater 33:2214089

Article  CAS  Google Scholar 

Ma X, Jin H, Ren Y et al (2022) A tripartite-enzyme via curcumin regarded as zymoexciter towards highly efficient relieving reperfusion injury. Chem Eng J 442:136029

Article