Development and validation of a prediction model for the depressive symptom risk in commercial airline pilots

COVID-19 Mental Disorders Collaborators. Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic. Lancet. 2020;2021(398):1700–12

Liu J, Wu J, Wang J, Chen S, Yin X, Gong Y. Prevalence and associated factors for depressive symptoms among the general population from 31 provinces in China: the utility of social determinants of health theory. J Affect Disord. 2024;347:269–77.

Article  PubMed  Google Scholar 

Robertson R, Robertson A, Jepson R, Maxwell M. Walking for depression or depressive symptoms: a systematic review and meta-analysis. Ment Health Phys Act. 2012;5:66–75.

Article  Google Scholar 

Ayuso-Mateos JL, Nuevo R, Verdes E, Naidoo N, Chatterji S. From depressive symptoms to depressive disorders: the relevance of thresholds. Br J Psychiatry. 2010;196:365–71.

Article  PubMed  Google Scholar 

Klein DN. Assessment of depression in adults and youth. Assessment. 2024;31:110–25.

Article  PubMed  Google Scholar 

Deng M-G, Liu F, Liang Y, Wang K, Nie J-Q, Liu J. Association between frailty and depression: a bidirectional Mendelian randomization study. Sci Adv. 2023;9:eadi3902.

AlMuammar S, Alkhaldi R, Alsharif R, Allbdi D, Alasmari M, Alasmari B, et al. Navigating the skies: a cross-sectional study of depression among Saudi Arabian airline pilots. J Occup Med Toxicol. 2024;19:36.

Article  PubMed  PubMed Central  Google Scholar 

Newcomb RD, Steffen MW, Breeher LE, Sturchio GM, Murad MH, Wang Z, et al. Screening for depression in the occupational health setting. Occupational Medicine (Oxford, England). 2016;66:390.

Article  CAS  PubMed  Google Scholar 

Wu AC, Donnelly-McLay D, Weisskopf MG, McNeely E, Betancourt TS, Allen JG. Airplane pilot mental health and suicidal thoughts: a cross-sectional descriptive study via anonymous web-based survey. Environ Health. 2016;15:121.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Schonfeld IS, Bianchi R. From burnout to occupational depression: recent developments in research on job-related distress and occupational health. Front Public Health. 2021;9: 796401.

Article  PubMed  PubMed Central  Google Scholar 

Karkala A, Moschonas S, Sykas G, Karagianni M, Gilou S, Papaefthymiou O, et al. Sleep quality and mental health consequences of COVID-19 pandemic in the aviation community in Greece. J Occup Environ Med. 2022;64:e567–74.

Article  PubMed  PubMed Central  Google Scholar 

Wang W, Yan Y, Guo Z, Hou H, Garcia M, Tan X, et al. All around suboptimal health — a joint position paper of the Suboptimal Health Study Consortium and European Association for Predictive, Preventive and Personalised Medicine. EPMA J. 2021;12:403.

Article  PubMed  PubMed Central  Google Scholar 

Shen L, Xu X, Yue S, Yin S. A predictive model for depression in Chinese middle-aged and elderly people with physical disabilities. BMC Psychiatry. 2024;24:305.

Article  PubMed  PubMed Central  Google Scholar 

Kuang Y, Liao X, Jiang Z, Gu Y, Liu B, Tan C, et al. Federated learning-based prediction of depression among adolescents across multiple districts in China. J Affect Disord. 2025;369:625–32.

Article  PubMed  Google Scholar 

Jeong Y-W, Kim J-H. Depression, anxiety, stress and anger of the cabin crew during the COVID-19 pandemic in South Korea. Healthcare (Basel). 2022;10:1952.

Article  PubMed  Google Scholar 

Taillard J, Sagaspe P, Philip P, Bioulac S. Sleep timing, chronotype and social jetlag: Impact on cognitive abilities and psychiatric disorders. Biochem Pharmacol. 2021;191: 114438.

Article  CAS  PubMed  Google Scholar 

He X, Nie X, Zhou R, Yang J, Wu R. The risk-taking behavioural intentions of pilots in adverse weather conditions: an application of the theory of planned behaviour. Ergonomics. 2023;66:1043–56.

Article  PubMed  Google Scholar 

Riemann D, Krone LB, Wulff K, Nissen C. Sleep, insomnia, and depression. Neuropsychopharmacology. 2020;45:74–89.

Article  PubMed  Google Scholar 

Park C, Rosenblat JD, Brietzke E, Pan Z, Lee Y, Cao B, et al. Stress, epigenetics and depression: a systematic review. Neurosci Biobehav Rev. 2019;102:139–52.

Article  CAS  PubMed  Google Scholar 

Crouse JJ, Carpenter JS, Song YJC, Hockey SJ, Naismith SL, Grunstein RR, et al. Circadian rhythm sleep-wake disturbances and depression in young people: implications for prevention and early intervention. Lancet Psychiatry. 2021;8:813–23.

Article  PubMed  Google Scholar 

Golubnitschaja O, Costigliola V. General Report & Recommendations in Predictive, Preventive and Personalised Medicine 2012: White Paper of the European Association for Predictive, Preventive and Personalised Medicine. EPMA J. 2012;3:14.

Article  PubMed  PubMed Central  Google Scholar 

Curran E, Perra O, Rosato M, Ferry F, Leavey G. Complex childhood trauma, gender and depression: patterns and correlates of help-seeking and maladaptive coping. J Affect Disord. 2021;292:603–13.

Article  PubMed  Google Scholar 

Korja R, Nolvi S, Scheinin NM, Tervahartiala K, Carter A, Karlsson H, et al. Trajectories of maternal depressive and anxiety symptoms and child’s socio-emotional outcome during early childhood. J Affect Disord. 2024;349:625–34.

Article  PubMed  Google Scholar 

Lv J, Ren H, Guo X, Meng C, Fei J, Mei H, et al. Nomogram predicting bullying victimization in adolescents. J Affect Disord. 2022;303:264–72.

Article  PubMed  Google Scholar 

Costantini L, Pasquarella C, Odone A, Colucci ME, Costanza A, Serafini G, et al. Screening for depression in primary care with Patient Health Questionnaire-9 (PHQ-9): A systematic review. J Affect Disord. 2021;279:473–83.

Article  PubMed  Google Scholar 

Zhang E, Li H, Han H, Wang Y, Cui S, Zhang J, et al. Dietary Rhythmicity and Mental Health Among Airline Personnel. JAMA Netw Open. 2024;7: e2422266.

Article  PubMed  Google Scholar 

Dyball D, Bennett AN, Schofield S, Cullinan P, Boos CJ, Bull AMJ, et al. Mental health outcomes of male UK military personnel deployed to Afghanistan and the role of combat injury: analysis of baseline data from the ADVANCE cohort study. Lancet Psychiatry. 2022;9:547–54.

Article  PubMed  Google Scholar 

Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001;16:606–13.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Buysse DJ, Reynolds CF, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res. 1989;28:193–213.

Article  CAS  PubMed  Google Scholar 

Chunnan L, Shaomei S, Wannian L. The association between sleep and depressive symptoms in US adults: data from the NHANES (2007–2014). Epidemiol Psychiatr Sci. 2022;31: e63.

Article  PubMed  PubMed Central  Google Scholar 

Pearce M, Garcia L, Abbas A, Strain T, Schuch FB, Golubic R, et al. Association between physical activity and risk of depression. JAMA Psychiat. 2022;79:550–9.

Article  Google Scholar 

Zhou Q, Guo C, Yang X, He N. Dose–response association of total sedentary behaviour and television watching with risk of depression in adults: a systematic review and meta-analysis. J Affect Disord. 2023;324:652–9.

Article  PubMed  Google Scholar 

Yue S, Li S, Huang X, Liu J, Hou X, Zhao Y, et al. Machine learning for the prediction of acute kidney injury in patients with sepsis. J Transl Med. 2022;20:215.

Demirjian S, Bashour CA, Shaw A, Schold JD, Simon J, Anthony D, et al. Predictive accuracy of a perioperative laboratory test-based prediction model for moderate to severe acute kidney injury after cardiac surgery. JAMA. 2022;327:956–64.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yu Y, Tan Y, Xie C, Hu Q, Ouyang J, Chen Y, et al. Development and validation of a preoperative magnetic resonance imaging radiomics-based signature to predict axillary lymph node metastasis and disease-free survival in patients with early-stage breast cancer. JAMA Netw Open. 2020;3: e2028086.

Article  PubMed  PubMed Central 

Comments (0)

No login
gif