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Trends in pulmonary embolism mortality among older adults with lung cancer in the united States, 1999–2020
Trends in pulmonary embolism mortality among older adults with lung cancer in the united States, 1999–2020
This nationwide study analyzed mortality trends in U.S. adults aged 65 years and above, pulmonary embolism mortality among...
Ticagrelor-Based antiplatelet therapy versus aspirin alone after coronary artery bypass grafting: A systematic review and Meta-Analysis with trial sequential analysis
Ticagrelor-Based antiplatelet therapy versus aspirin alone after coronary artery bypass grafting: A systematic review and Meta-Analysis with trial sequential analysis
Introduction: Coronary artery bypass grafting (CABG) is a common surgical treatment for coronary artery disease; however, ...
Prospective evidence of increased venous thromboembolism in hereditary hemorrhagic telangiectasia
Prospective evidence of increased venous thromboembolism in hereditary hemorrhagic telangiectasia
Hereditary Hemorrhagic Telangiectasia (HHT) is a rare vascular disease (1/5,000 prevalence) characterized by mucocutaneous...
Cangrelor in ST-segment elevation myocardial infarction with high on-treatment platelet reactivity: a pilot randomized trial
Cangrelor in ST-segment elevation myocardial infarction with high on-treatment platelet reactivity: a pilot randomized trial
High on P2Y12 inhibitor platelet reactivity (HPR) is frequent at the time of percutaneous coronary intervention (PCI) for ...
Efficacy and safety of direct oral anticoagulants and low molecular weight heparin for cancer-associated venous thromboembolism in patients with extremes in bodyweight
Efficacy and safety of direct oral anticoagulants and low molecular weight heparin for cancer-associated venous thromboembolism in patients with extremes in bodyweight
The purpose of this study is to describe the safety and efficacy of direct oral anticoagulants (DOACs) and low molecular w...
Association of left ventricular outflow tract velocity-time integral with severity of pulmonary embolism in patients treated with catheter-directed therapies
Association of left ventricular outflow tract velocity-time integral with severity of pulmonary embolism in patients treated with catheter-directed therapies
Pulmonary embolism is a leading cause of cardiovascular death. Given the increased use of catheter directed therapies (CDT...
Metabolic syndrome and venous thromboembolism: the role of abdominal obesity and sex differences
Metabolic syndrome and venous thromboembolism: the role of abdominal obesity and sex differences
Metabolic syndrome (MetS) is a cluster of cardiovascular risk factors, including abdominal obesity, insulin resistance, dy...
Association between elevated D-dimer levels and deep vein thrombosis following neurosurgery
Association between elevated D-dimer levels and deep vein thrombosis following neurosurgery
Despite thromboprophylaxis, neurosurgical patients remain at high post-operative thromboembolic risk, but early diagnosis ...
Artificial intelligence for venous thromboembolism risk stratification in surgical patients: a systematic review
Artificial intelligence for venous thromboembolism risk stratification in surgical patients: a systematic review
Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a significant complicat...
The procoagulant effect described in preparations of plasma-derived β2-glycoprotein I (β2GPI) is mediated by contamination with factor XIa.
The procoagulant effect described in preparations of plasma-derived β2-glycoprotein I (β2GPI) is mediated by contamination with factor XIa.
Beta-2 glycoprotein I (β2GPI) is the primary antigen targeted by thrombotic antiphospholipid antibodies and is a plas...
A Growing mortality divide: demographic and regional disparities in thromboembolism with hypertension, U.S. 1999–2023
A Growing mortality divide: demographic and regional disparities in thromboembolism with hypertension, U.S. 1999–2023
Hypertension is a widespread chronic illness. Hypertension is significantly associated with thromboembolic disease, includ...
Clinical outcomes and missed benefits related to clopidogrel overuse in acute coronary syndrome
Clinical outcomes and missed benefits related to clopidogrel overuse in acute coronary syndrome
The optimal choice of oral P2Y12 inhibitor in patients with acute coronary syndrome (ACS) remains debated, particularly fo...
Atrial fibrillation detected after ischemic stroke (AFDAS) diagnosed by short-term monitoring: the importance of frontal hypoperfusion
Atrial fibrillation detected after ischemic stroke (AFDAS) diagnosed by short-term monitoring: the importance of frontal hypoperfusion
Atrial fibrillation detected after stroke (AFDAS) may be either newly emergent or previously undiagnosed, with potential n...
Insights on management of recurrence of Cancer-associated isolated distal deep vein thrombosis
Insights on management of recurrence of Cancer-associated isolated distal deep vein thrombosis
Isolated distal deep vein thrombosis (IDDVT) is the most prevalent form of deep vein thrombosis (DVT), comprising up to 50...
Bleeding events in Asian patients with cancer-associated thrombosis: a 10-year single-centre experience
Bleeding events in Asian patients with cancer-associated thrombosis: a 10-year single-centre experience
Malignancy is a well-recognised major risk factor for venous thromboembolism (VTE). While anticoagulation is the cornersto...
Pulmonary embolism mortality in the United States: a nationwide analysis
Pulmonary embolism mortality in the United States: a nationwide analysis
Pulmonary embolism (PE) remains a major cause of cardiovascular mortality in the United States. Despite therapeutic advanc...
Angio-Seal plug-based versus dual ProGlide for transfemoral hemostasis in transcatheter aortic valve replacement: a systematic review and meta-analysis
Transcatheter aortic valve replacement (TAVR) carries risks of vascular and bleeding complications. We aimed to study the ...
Establishment and validation of a machine learning-based prediction model for sepsis-induced coagulopathy
Establishment and validation of a machine learning-based prediction model for sepsis-induced coagulopathy
A LightGBM model was developed to predict sepsis-induced coagulopathy (SIC) within 72 h of ICU admission using ro...
Prophylactic anticoagulation following anterior ST-elevation myocardial infarction for prevention of left ventricular thrombus: a narrative review
Prophylactic anticoagulation following anterior ST-elevation myocardial infarction for prevention of left ventricular thrombus: a narrative review
Left ventricular thrombus (LVT) is a recognized complication following ST-elevation myocardial infarction (STEMI), most co...
Indobufen versus aspirin for platelet inhibition: efficacy and safety insights from the INSURE and OPTION trials
Indobufen versus aspirin for platelet inhibition: efficacy and safety insights from the INSURE and OPTION trials
This study systematically compares the antiplatelet efficacy and safety of indobufen and aspirin based on two key clinical...
Real-world data on direct oral anticoagulants in BCR::ABL1-negative myeloproliferative neoplasms (MPNs): a multicenter retrospective study on behalf of scientific subcommittee on MPNs for Turkish society of hematology
Real-world data on direct oral anticoagulants in BCR::ABL1-negative myeloproliferative neoplasms (MPNs): a multicenter retrospective study on behalf of scientific subcommittee on MPNs for Turkish society of hematology
BCR::ABL1-negative myeloproliferative neoplasms (MPNs) pose a substantial risk of thrombosis, leading to significant morbi...
Impact of antiplatelets, anticoagulants and cyclic nucleotide stimulators on neutrophil extracellular traps (NETs) and inflammatory markers during COVID-19
Impact of antiplatelets, anticoagulants and cyclic nucleotide stimulators on neutrophil extracellular traps (NETs) and inflammatory markers during COVID-19
While the association between coronavirus disease-19 (COVID-19) and neutrophils extracellular traps (NETs) is recognized, ...
Incidence and risk factors for venous thromboembolism in gynecological cancer: the GOTIC-VTE trial
Incidence and risk factors for venous thromboembolism in gynecological cancer: the GOTIC-VTE trial
Real-world data on venous thromboembolism (VTE) in Japanese patients with gynecological cancer are lacking. The GOTIC-VTE ...
The foundation for investigating factor XI as a target for inhibition in human cardiovascular disease
The foundation for investigating factor XI as a target for inhibition in human cardiovascular disease
Anticoagulant therapy is a mainstay in the management of patients with cardiovascular disease and related conditions chara...
Discovery of a new lead molecule to develop a novel class of human factor XIIa inhibitors
Discovery of a new lead molecule to develop a novel class of human factor XIIa inhibitors
Factor XIIa (FXIIa) is a plasma serine protease within the contact activation pathway. Inhibiting FXIIa could offer a viab...
Heparin-like effect of a dual antiplatelet and anticoagulant (APAC) agent on red blood cell deformability and aggregation in an experimental model
Heparin-like effect of a dual antiplatelet and anticoagulant (APAC) agent on red blood cell deformability and aggregation in an experimental model
Treatments with different antithrombotic agents can affect micro-rheological variables, such as red blood cell (RBC) defor...
Factor XI: structure, function and therapeutic inhibition
Factor XI: structure, function and therapeutic inhibition
Arterial and venous thromboembolism is a major medical concern that requires therapeutic anticoagulation in various medica...
RNAi targeting LMAN1-MCFD2 complex promotes anticoagulation in mice
RNAi targeting LMAN1-MCFD2 complex promotes anticoagulation in mice
Combined deficiency of coagulation factor V (FV) and factor VIII (FVIII) is a rare bleeding disease caused by variants in ...
Thrombin generation after prothrombin complex concentrate or plasma transfusion during cardiac surgery
Thrombin generation after prothrombin complex concentrate or plasma transfusion during cardiac surgery
Thrombin generation (TG) is reduced after cardiac surgery using cardiopulmonary bypass (CPB), contributing to coagulopathy...
Evaluation of unfractionated heparin therapy for venous thromboembolism using adjusted body weight in elderly or higher weight patients
Evaluation of unfractionated heparin therapy for venous thromboembolism using adjusted body weight in elderly or higher weight patients
The use of weight-based unfractionated heparin (UFH) infusions is the standard of care in hospital management of venous th...
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