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miR-181a post-transcriptionally targets GRK2 to limit maladaptive signaling in cardiomyocytes
BackgroundPathological upregulation of G protein-coupled receptor kinase 2 (GRK2) is a hallmark of heart failure and contr...
Predictive value of ALBI score in assessing prognosis of NSTEMI: a retrospective cohort study
ObjectiveThis study aims to evaluate the predictive value of the albumin-bilirubin (ALBI) score for mortality risk in pati...
Recurrent myocarditis in a young female with a desmoplakin gene variant: a case report and literature review
BackgroundRecurrent myocarditis is commonly associated with infectious or immune etiologies. This case suggests a potentia...
Cross-national associations between adulthood stressful life events and incident heart disease: a multicohort harmonized analysis
BackgroundWhether links between adulthood stressful life events (SLEs) and heart disease are comparable across countries—a...
A new approach methodology for studying intrinsic ventricular arrhythmias in Fabry disease
BackgroundSudden cardiac death is a common but poorly understood cause of mortality in Fabry disease (FD). We investigated...
Clinical characteristics and outcomes of lean diabetes mellitus in patients with moderate and severe aortic stenosis
BackgroundLean diabetes mellitus (DM), defined as the presence of DM in patients with low-normal body mass index (BMI), is...
The relationship between discharge destination and rehospitalization in Chinese patients with heart failure: a cohort study
BackgroundThe high readmission rate among heart failure (HF) patients is a significant concern, but limited research has e...
Risk prediction models for venous thromboembolism in stroke: a systematic review and meta-analysis
ObjectiveThis study aimed to systematically evaluate risk prediction models for venous thromboembolism (VTE) in stroke pat...
Case Report: Exploring KMT2D mutation in Shone syndrome
IntroductionShone syndrome is a rare congenital heart disease characterized by multilevel left-sided obstructive lesions. ...
Application and efficacy evaluation of thoracoscopic techniques in ventricular tumors resection
BackgroundAlthough fully thoracoscopic resection of atrial tumors has become well established, evidence supporting non-rob...
Carotid plaque formation prediction model and validation: a case-control study
BackgroundCarotid plaque serves as an early window into atherosclerosis; however, more convenient tools for plaque risk st...
Pre- and post-pandemic comparisons in cardiovascular markers: a population-based study
Introduction In 2020, the world witnessed a pandemic of historical proportions. One of the main concerns, in addition to ...
Mechanisms of inflammatory microenvironment formation in cardiometabolic diseases: molecular and cellular perspectives
Introduction Cardiometabolic diseases (CMD) represent a complex cluster of disorders, primarily encompassing atherosclero...
Establishment and validation of a nomogram for coronary artery lesions in children with Kawasaki disease
Introduction Kawasaki disease (KD) is a benign but self-limited systemic vasculitis, primarily affecting children. The cl...
Chinese and western medicine treatment of myocardial fibrosis drugs
1 Introduction MF frequently appears as a pathological feature in a range of cardiovascular conditions, such as myocardi...
Predictive value of NT-pro BNP on outcomes of children with ventricular septal defect surgery
Introduction Ventricular septal defect (VSD) is one of the most common congenital cardiac structural anomalies. While a m...