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Heartbeat: Proteomics for predicting risk and identifying mechanisms of disease progression
Heartbeat: Proteomics for predicting risk and identifying mechanisms of disease progression
Proteomic profiling allows measurement of thousands of proteins simultaneously from blood or tissue samples in patients wi...
Asynchronous communication for medical journal editorial teams in a diverse global research community
Asynchronous communication for medical journal editorial teams in a diverse global research community
Medical journal editors face many challenges in the ongoing transformation of scientific publishing including the replacem...
Novel risk score to predict ischaemic and bleeding risk after acute coronary syndrome: new tools for an upcoming new era?
Novel risk score to predict ischaemic and bleeding risk after acute coronary syndrome: new tools for an upcoming new era?
It is not the strongest of the species that survives, nor the most intelligent that survives. It is the one that is the mo...
One step closer to the new frontiers of healthcare for cardiomyopathy patients
One step closer to the new frontiers of healthcare for cardiomyopathy patients
There were great advances in the treatment of heart failure (HF) over the past decades, characterised by the inclusion of ...
Relationship between the aortic root and the atrioventricular conduction axis
Relationship between the aortic root and the atrioventricular conduction axis
Damage to the atrioventricular conduction axis continues to be a problem subsequent to transcatheter implantation of aorti...
Difficult echocardiogram after pericardiocentesis
Difficult echocardiogram after pericardiocentesis
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Burden and prognostic impact of cardiovascular disease in patients with cancer
Burden and prognostic impact of cardiovascular disease in patients with cancer
The number of patients at the intersection of cancer and cardiovascular disease (CVD) is increasing, reflecting ageing glo...
Prediction of worsening heart failure in hypertrophic cardiomyopathy using plasma proteomics
Prediction of worsening heart failure in hypertrophic cardiomyopathy using plasma proteomics
WHAT IS ALREADY KNOWN ON THIS TOPICHeart failure (HF) is a common complication of hypertrophic cardiomyopathy (HCM), yet p...
Paired risk scores to predict ischaemic and bleeding risk twenty-eight days to one year after an acute coronary syndrome
Paired risk scores to predict ischaemic and bleeding risk twenty-eight days to one year after an acute coronary syndrome
IntroductionClinical trials have established that the use of more potent and prolonged antithrombotic medications after an...
Non-COVID-19 cardiovascular pathology from return-to-play screening in college athletes after COVID-19
Non-COVID-19 cardiovascular pathology from return-to-play screening in college athletes after COVID-19
WHAT IS ALREADY KNOWN ON THIS TOPICPreparticipation screening in competitive athletes using history and physical examinati...
Restoration of right ventricular function in the treatment of pulmonary arterial hypertension
Restoration of right ventricular function in the treatment of pulmonary arterial hypertension
Baseline characteristicsMean age of the study population was 50±17 years; most patients were female (73%), and the majorit...
Sleep-disordered breathing and cardiovascular disease: who and why to test and how to intervene?
Sleep-disordered breathing and cardiovascular disease: who and why to test and how to intervene?
Sleep-disordered breathing (SDB) is common in individuals with established cardiovascular disease (CVD), particularly thos...
Exploring the mechanisms responsible for reduced systolic function in high-gradient aortic stenosis
Exploring the mechanisms responsible for reduced systolic function in high-gradient aortic stenosis
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Heartbeat: atrial fibrillation phenotyping identifies patients at high risk of adverse events
Heartbeat: atrial fibrillation phenotyping identifies patients at high risk of adverse events
Atrial fibrillation (AF) is primarily classified based on duration of the arrhythmia and the risk of stroke. However, the ...
Atrial fibrillation phenotypes: the route to personalised care?
Atrial fibrillation phenotypes: the route to personalised care?
Atrial fibrillation (AF) is the most common arrhythmia in adults and is responsible for significant morbidity and mortalit...
Transcatheter atrial septal defect closure in the elderly: the decisive role of balloon testing
Transcatheter atrial septal defect closure in the elderly: the decisive role of balloon testing
Atrial septal defect (ASD), one of the most common types of congenital heart disease, can be diagnosed and treated early i...
Right-sided mechanical valve prostheses in adults with congenital heart disease
Right-sided mechanical valve prostheses in adults with congenital heart disease
Congenital heart disease (CHD) commonly includes right-sided valvular heart disease. Patients with CHD may require multipl...
Update on advanced interventional neuromodulatory approaches to lower blood pressure
Update on advanced interventional neuromodulatory approaches to lower blood pressure
Herein, we review interventional peripheral neuromodulatory approaches to reduce blood pressure (BP), specifically focusin...
Transcatheter closure of atrial septal defect in the elderly: a systematic review and meta-analysis
Transcatheter closure of atrial septal defect in the elderly: a systematic review and meta-analysis
IntroductionAtrial septal defect (ASD) closure is recommended in patients with right ventricular (RV) volume overload with...
Dyspnoea and murmur in a young adult
Dyspnoea and murmur in a young adult
Clinical introductionA quadragenarian patient presented with functional class II dyspnoea for 6 months. Clinical examinati...
Rate control in atrial fibrillation, calcium channel blockers versus beta-blockers
Rate control in atrial fibrillation, calcium channel blockers versus beta-blockers
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Phenotyping of atrial fibrillation with cluster analysis and external validation
Phenotyping of atrial fibrillation with cluster analysis and external validation
IntroductionAtrial fibrillation (AF) is the most common arrhythmia in developed countries,1 and its prevalence is graduall...
Association between troponin level and medium-term mortality in 20 000 hospital patients
Association between troponin level and medium-term mortality in 20 000 hospital patients
What is already known on this topicCardiac troponin (cTn) is an essential component in the diagnosis (or exclusion) of typ...
Outcomes after implantation of right-sided mechanical valve prostheses in congenital heart disease
Outcomes after implantation of right-sided mechanical valve prostheses in congenital heart disease
Background Bioprosthetic valves are often used for pulmonary valve replacement (PVR) and tricuspid valve replacement (TVR)...
Reflex syncope: assessment and management
Reflex syncope: assessment and management
Learning objectivesTo summarise the key steps in the reflex syncope workup.To present currently available treatments for r...
Alcohol septal ablation in patients aged 75 years or older with hypertrophic obstructive cardiomyopathy
Alcohol septal ablation in patients aged 75 years or older with hypertrophic obstructive cardiomyopathy
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Roles for cardiologists in government, research councils and regulatory sectors
Roles for cardiologists in government, research councils and regulatory sectors
IntroductionThis article focuses on the potential roles for cardiologists in governmental and regulatory sectors, as well ...
Heartbeat: ultra-processed foods and atrial fibrillation risk
Heartbeat: ultra-processed foods and atrial fibrillation risk
Recommendations for primary prevention of atrial fibrillation (AF) emphasise the role of weight loss and other lifestyle r...