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SCI Abstract
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ACEi and ARBs as Primary Prevention of Cancer Therapy-Related Cardiomyopathy in Patients Undergoing Chemotherapy with Anthracyclines: A Systematic Review and Meta-Analysis
Anthracyclines treat a myriad of malignancies; however, they are known to lead to cancer therapy-related cardiomyopathy (C...
Cardiology And Therapy
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Rationale and Design of ANTHOLOGY: An ATTR Amyloidosis Real-World Evidence Program Aiming to Address Gaps in Amyloidosis Care
Patients with amyloid transthyretin (ATTR) amyloidosis typically experience rapid disease progression, poor treatment outc...
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The Atrial FibriLlatiOn Registry (FLOW-AF): Patient Characteristics, Treatment Patterns, and Outcomes in Egypt
Real-world data on atrial fibrillation (AF) in the Middle East and North Africa (MENA) region, including Egypt, are sparse...
Cardiology And Therapy
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Impella Versus VA-ECMO for Patients with Cardiogenic Shock: Preliminary Cost-Effectiveness Analysis in the Italian Context
Cardiogenic shock (CS) is a life-threatening failure of the heart to supply adequate blood, requiring immediate treatment....
Cardiology And Therapy
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Stressful Life Events and Heart Failure: A Mixed-Method Study to Analyze the Patient’s Perspective
The challenge in heart failure medical practice is to address the clinical and laboratory method integrations for the shar...
Cardiology And Therapy
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Arterial Hypertension and Associated Risk Factors in Kazakhstan: An Analysis of Blood Pressure Screening Results from May Measurement Month 2021–2023
May Measurement Month (MMM) is a global campaign with the aim to improve awareness of arterial hypertension (AH). Kazakhst...
Cardiology And Therapy
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Effect of Mavacamten on Echocardiographic Features in Chinese Patients with Obstructive Hypertrophic Cardiomyopathy: Results from the EXPLORER-CN Study
Mavacamten, a cardiac myosin inhibitor, has demonstrated positive outcomes in left ventricular outflow tract (LVOT) gradie...
Cardiology And Therapy
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Effectiveness and Tolerability of Trimetazidine 80 mg Once Daily in Patients with Chronic Coronary Syndrome in Brazil: The V-GOOD Observational Study
The V-GOOD study evaluated the effectiveness of trimetazidine modified-release (MR) 80 mg once daily (OD) in pati...
Cardiology And Therapy
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Efficacy and Safety of the Fixed-Dose Combination of Atorvastatin/Fenofibrate Versus Atorvastatin on the Lipid Profile of Patients with Type 2 Diabetes and Dyslipidemia
In dyslipidemia associated with type 2 diabetes (T2DM), elevated triglycerides (TG), increased low-density lipoprotein cho...
Cardiology And Therapy
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Left Ventricular Mechanical Circulatory Support Devices for Cardiogenic Shock After Myocardial Infarction
Cardiogenic shock is the most common cause of mortality in patients with acute myocardial infarction (AMI). Historically, ...
Cardiology And Therapy
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Patient Experience of Heart Disease with Elevated Lipoprotein(a): Views from a Patient, His Physician, and a Patient Association
This article presents three points of view on lipoprotein(a) [Lp(a)]: that of a patient, his endocrinologist, and a patien...
Cardiology And Therapy
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An External Control Arm for the Oral Factor XIa Inhibitor Asundexian Phase 2 Trial in Atrial Fibrillation (PACIFIC-AF) Using Electronic Health Records
The aim of this study was to assess the applicability of an external control arm (ECA) approach in the clinical developmen...
Cardiology And Therapy
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Transcatheter Versus Surgical Aortic Valve Replacement in Patients with Polyvascular Disease
There is a paucity of data regarding the trends and comparative outcomes of transcatheter aortic valve replacement (TAVR) ...
Cardiology And Therapy
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Safety and Efficacy of Tafamidis in Chinese Patients with Transthyretin Amyloid Cardiomyopathy
Tafamidis is approved in many countries for the treatment of patients with transthyretin amyloid cardiomyopathy (ATTR-CM)....
Cardiology And Therapy
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Association Between Insulin Resistance and Incomplete Endothelization of LAAC Devices in Patients with Atrial Fibrillation: A Retrospective Study
Incomplete endothelialization (IDE) of left atrial appendage closure (LAAC) devices increases the risk of device-related t...
Cardiology And Therapy
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Clinical and Genotype Characteristics and Symptom Migration in Patients With Mixed Phenotype Transthyretin Amyloidosis from the Transthyretin Amyloidosis Outcomes Survey
Transthyretin amyloidosis (ATTR amyloidosis) is primarily associated with a cardiac or neurologic phenotype, but a mixed p...
Cardiology And Therapy
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Can Artificial Intelligence Improve the Readability of Patient Education Materials on Aortic Stenosis? A Pilot Study
The advent of generative artificial intelligence (AI) dialogue platforms and large language models (LLMs) may help facilit...
Cardiology And Therapy
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Add-on Sacubitril/Valsartan Therapy Induces Left Ventricular Remodeling in Non-responders to Cardiac Resynchronization Therapy to a Similar Extent as in Heart Failure Patients Without Resynchronization
Non-responders to cardiac resynchronization therapy (CRT-NR) have poor prognosis. Sacubitril/valsartan (SV) treatment impr...
Cardiology And Therapy
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Effect of Macitentan in Pulmonary Arterial Hypertension and the Relationship Between Echocardiography and cMRI Variables: REPAIR Echocardiography Sub-study Results
The aim of this sub-study was to evaluate the relationship between echocardiography (echo) and cardiac magnetic resonance ...
Cardiology And Therapy
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Real-World Risk of Recurrent Cardiovascular Events in Atherosclerotic Cardiovascular Disease Patients with LDL-C Above Guideline-Recommended Threshold: A Retrospective Observational Study
The 2021 Canadian Cardiovascular Society (CCS) guidelines recommend intensive low-density lipoprotein cholesterol (LDL-C) ...
Cardiology And Therapy
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Factor XI Inhibitors: A New Horizon in Anticoagulation Therapy
Anticoagulation therapy has undergone significant evolution, marked by the emergence of direct oral anticoagulants with di...
Cardiology And Therapy
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Real-World Safety and Effectiveness of a 4-Factor Prothrombin Complex Concentrate in Japanese Patients Experiencing Major Bleeding: A Post-marketing Surveillance Study
Limited data are available regarding the safety and effectiveness of 4-factor prothrombin complex concentrate (4F-PCC) in ...
Cardiology And Therapy
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Contemporary Management of Cardiomyopathy and Heart Failure in Pregnancy
Cardiovascular disease is the primary cause of pregnancy-related mortality and morbidity in the United States, and materna...
Cardiology And Therapy
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Cerebral Embolic Protection in Transcatheter Aortic Valve Implantation Using the Sentinel Cerebral Protection System: A Systematic Review and Meta-Analysis
Transcatheter aortic valve implantation (TAVI) plays a vital role in patients with symptomatic aortic stenosis. Despite th...
Cardiology And Therapy
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Single-Pill, Triple Antihypertensive Therapy in Rural Sub-Saharan Africa: Preliminary Experience
Worldwide, arterial hypertension is the foremost preventable and modifiable cardiovascular risk factor. In addition to lif...
Cardiology And Therapy
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The Clear Value of Coronary Artery Calcification Evaluation on Non-Gated Chest Computed Tomography for Cardiac Risk Stratification
To enhance risk stratification in patients suspected of coronary artery disease, the assessment of coronary artery calcium...
Cardiology And Therapy
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Targeting Lipoprotein(a): Can RNA Therapeutics Provide the Next Step in the Prevention of Cardiovascular Disease?
Numerous genetic and epidemiologic studies have demonstrated an association between elevated levels of lipoprotein(a) (Lp[...
Cardiology And Therapy
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Automatic Quantification of Local Plaque Thickness Differences as Assessed by Serial Coronary Computed Tomography Angiography Using Scan-Quality-Based Vessel-Specific Thresholds
The use of serial coronary computed tomography angiography (CCTA) allows for the early assessment of coronary plaque progr...
Cardiology And Therapy
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Impact of Access Site on Periprocedural Bleeding and Cerebral and Coronary Events in High-Bleeding-Risk Percutaneous Coronary Intervention: Findings from the RIVA-PCI Trial
The preference for using transradial access (TRA) over transfemoral access (TFA) in patients requiring percutaneous corona...
Cardiology And Therapy
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Dual-Pathway Inhibition with Rivaroxaban and Low-Dose Aspirin Does Not Alter Immune Cell Responsiveness and Distribution in Patients with Coronary Artery Disease
Cardiovascular diseases (CVD) are the leading cause of death globally. Inflammation is an important driver of CVD where ti...
Cardiology And Therapy
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