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The Sacral Erector Spinae Plane Block: A Narrative Review
The Sacral Erector Spinae Plane Block: A Narrative Review
The sacral erector spinae plane (S-ESP) block is a recently described regional anesthesia technique that targets sacral de...
Flurbiprofen Axetil Combined with Ultrasound-Guided Intercostal Nerve Block for Preoperative Analgesia in Patients with Traumatic Multiple Rib Fractures: A Randomized Controlled Trial
Flurbiprofen Axetil Combined with Ultrasound-Guided Intercostal Nerve Block for Preoperative Analgesia in Patients with Traumatic Multiple Rib Fractures: A Randomized Controlled Trial
Given the limitations of single-modality analgesia for rib fractures, this study aimed to determine whether combining syst...
Next-Generation SCS Programming Platform: Enhancing ECAP Fidelity and Objectivity to Improve Patient Experience
Next-Generation SCS Programming Platform: Enhancing ECAP Fidelity and Objectivity to Improve Patient Experience
Evoked compound action potentials (ECAPs) are neurophysiological biomarkers of neural activation during spinal cord stimul...
Analgesic Efficacy and Adverse Effects of Epidural Ropivacaine Combined with Equipotent Alfentanil or Sufentanil for Labor Analgesia: A Multicenter Randomized Controlled Single-Blind Trial
Analgesic Efficacy and Adverse Effects of Epidural Ropivacaine Combined with Equipotent Alfentanil or Sufentanil for Labor Analgesia: A Multicenter Randomized Controlled Single-Blind Trial
Epidural analgesia has shown high maternal–fetal safety and satisfactory analgesia. Sufentanil is associated with a ...
Screening and Management of Sleep Disorders in Patients with Fibromyalgia Syndrome: A French Multicenter, Prospective, Observational Study
Screening and Management of Sleep Disorders in Patients with Fibromyalgia Syndrome: A French Multicenter, Prospective, Observational Study
This study investigates the prevalence of sleep disorders among patients with fibromyalgia syndrome (FMS) in French pain c...
Economic and Treatment Burden of Chronic Low-Back Pain Patients Transitioning from Short-Acting to Long-Acting Opioids or Buprenorphine Buccal Film: US Claims Analysis
Economic and Treatment Burden of Chronic Low-Back Pain Patients Transitioning from Short-Acting to Long-Acting Opioids or Buprenorphine Buccal Film: US Claims Analysis
This study aimed to assess economic burden and treatment characteristics of patients with chronic low-back pain (cLBP) tra...
Real-World Retrospective Safety Analysis of OnabotulinumtoxinA for the Treatment of Patients with Chronic Migraine and Concomitant Therapeutic Indications
Real-World Retrospective Safety Analysis of OnabotulinumtoxinA for the Treatment of Patients with Chronic Migraine and Concomitant Therapeutic Indications
Patients receiving onabotulinumtoxinA treatment for chronic migraine (CM) may have coexisting diseases warranting multi-in...
Analgesic Effect of Laparoscopic Versus Ultrasound-Guided Quadratus Lumborum Block in Patients Undergoing Laparoscopic Nephrectomy: A Randomized Controlled Clinical Trial
Analgesic Effect of Laparoscopic Versus Ultrasound-Guided Quadratus Lumborum Block in Patients Undergoing Laparoscopic Nephrectomy: A Randomized Controlled Clinical Trial
Quadratus lumborum block (QLB), as a trunk regional block technique, can effectively alleviate postoperative pain in renal...
Ultrasound-Guided Radiofrequency Ablation of the Ilioinguinal Nerves to Treat Ilioinguinal Neuralgia: A Description of a Novel Approach
Ultrasound-Guided Radiofrequency Ablation of the Ilioinguinal Nerves to Treat Ilioinguinal Neuralgia: A Description of a Novel Approach
Ilioinguinal neuralgia is a commonly underdiagnosed and often refractory cause of chronic groin and lower abdominal pain. ...
Objective, Same-Day SCS Trials with ECAP-Controlled Closed-Loop Therapy: Depth of Response is Maintained from Trial to 12 months
Objective, Same-Day SCS Trials with ECAP-Controlled Closed-Loop Therapy: Depth of Response is Maintained from Trial to 12 months
Traditional spinal cord stimulation (SCS) trials often span several days, increasing the risks of infection, equipment fai...
Immuno-Inflammatory Mechanisms in the Chronification of Pain
Immuno-Inflammatory Mechanisms in the Chronification of Pain
Chronic pain affects 20% of the global population, with current treatments achieving meaningful relief in less than 30% of...
Pain Relief and Multidimensional Outcomes of Fast-Acting Subperception Spinal Cord Stimulation Therapy for Chronic Pain: The FAST Prospective, Multicenter Study
Pain Relief and Multidimensional Outcomes of Fast-Acting Subperception Spinal Cord Stimulation Therapy for Chronic Pain: The FAST Prospective, Multicenter Study
Fast-acting subperception therapy in spinal cord stimulation (FAST-SCS) uses low-frequency, subthreshold stimulation to en...
Acetyl--Carnitine in the Treatment of Peripheral Neuropathies: A Narrative Review
Acetyl--Carnitine in the Treatment of Peripheral Neuropathies: A Narrative Review
Acetyl-l-carnitine is an ester of l-carnitine, both endogenous molecules, with a vital role in lipid metabolism. Exogenous...
Association Between Triglyceride Glucose Index and Postherpetic Neuralgia in Patients with Acute Herpes Zoster: A Retrospective Study
Association Between Triglyceride Glucose Index and Postherpetic Neuralgia in Patients with Acute Herpes Zoster: A Retrospective Study
Insulin resistance (IR) is an important factor in the development of chronic pain. The triglyceride–glucose (TyG) in...
Efficacy of Transcutaneous Auricular Vagus Nerve Stimulation for Postoperative Pain Relief in Patients Undergoing Elective Laparoscopic Gastrointestinal Tumor Surgery
Efficacy of Transcutaneous Auricular Vagus Nerve Stimulation for Postoperative Pain Relief in Patients Undergoing Elective Laparoscopic Gastrointestinal Tumor Surgery
Acute postoperative pain remains prevalent among patients undergoing gastrointestinal tumor surgery. The study was conduct...
Real-World Safety and Effectiveness of Mirogabalin in Chinese Adults with Diabetic Peripheral Neuropathic Pain: a Protocol of ReMIssion Study
Real-World Safety and Effectiveness of Mirogabalin in Chinese Adults with Diabetic Peripheral Neuropathic Pain: a Protocol of ReMIssion Study
Mirogabalin is an oral Ca2+ channel α2δ ligand used for treating diabetic peripheral neuropathic pain (DPNP) in ...
The Association Between Body Mass Index and Acute Postoperative Pain in Bariatric Surgery Patients: A Prospective Cohort Study
The Association Between Body Mass Index and Acute Postoperative Pain in Bariatric Surgery Patients: A Prospective Cohort Study
The rising global prevalence of obesity has established bariatric surgery as a key therapeutic option; however, postoperat...
Efficacy and Safety of Ciprofol Versus Propofol as Anesthetic for Patients Undergoing Painless Colonoscopy
Efficacy and Safety of Ciprofol Versus Propofol as Anesthetic for Patients Undergoing Painless Colonoscopy
Ciprofol is a novel propofol analogue with a characteristic of hemodynamic stability. At present, there is a lack of resea...
Safety of Co-Crystal of Tramadol-Celecoxib (CTC) in Patients with Acute Moderate-to-Severe Pain: Pooled Analysis of Three Phase 3 Randomized Trials
Safety of Co-Crystal of Tramadol-Celecoxib (CTC) in Patients with Acute Moderate-to-Severe Pain: Pooled Analysis of Three Phase 3 Randomized Trials
Multi-modal analgesia is desirable for the management of acute pain since it can provide effective pain relief at lower do...
Comparison of Oliceridine to Remifentanil for Optimal Analgesia in Mechanical Ventilation (CO-ROAM): Study Protocol for a Multicenter Randomized Controlled Trial
Comparison of Oliceridine to Remifentanil for Optimal Analgesia in Mechanical Ventilation (CO-ROAM): Study Protocol for a Multicenter Randomized Controlled Trial
Critically ill patients often endure pain, a distressing experience that can trigger diverse pathophysiological consequenc...
Patients’ Experiences During the Long Journey Before Initiating Migraine Prevention with a Calcitonin Gene-Related Peptide (CGRP) Monoclonal Antibody (mAb)
Patients’ Experiences During the Long Journey Before Initiating Migraine Prevention with a Calcitonin Gene-Related Peptide (CGRP) Monoclonal Antibody (mAb)
Migraine is under-diagnosed and under-treated. Many people with migraine do not seek medical care, and those who do may in...
Clinical Efficacy of Auricular Vagus Nerve Stimulation in the Treatment of Chronic and Acute Pain: A Systematic Review and Meta-analysis
Clinical Efficacy of Auricular Vagus Nerve Stimulation in the Treatment of Chronic and Acute Pain: A Systematic Review and Meta-analysis
Current guidelines for pain treatment recommend a personalized, multimodal and interdisciplinary approach as well as the u...
An Additive Effect of Instrument-Assisted Soft Tissue Mobilization with Spinal Manipulation in Cervicogenic Headache: a Randomized Controlled Trial
An Additive Effect of Instrument-Assisted Soft Tissue Mobilization with Spinal Manipulation in Cervicogenic Headache: a Randomized Controlled Trial
There is a multitude of evidence supporting the use of manual and manipulative therapy techniques for patients with cervic...
Lumbar Sympathetic Block to Treat CRPS in an 18-Month-Old Girl: A Breaking Barriers Case Report and Review of Literature
Lumbar Sympathetic Block to Treat CRPS in an 18-Month-Old Girl: A Breaking Barriers Case Report and Review of Literature
Children under the age of 3 years have been diagnosed with complex regional pain syndrome (CRPS). They were found to be fu...
Preoperative Analgesia Efficacy of Liposomal Bupivacaine Following Pericapsular Nerve Group (PENG) Block in Patients with Hip Fracture: A Randomized Controlled Observer-Blinded Study
Preoperative Analgesia Efficacy of Liposomal Bupivacaine Following Pericapsular Nerve Group (PENG) Block in Patients with Hip Fracture: A Randomized Controlled Observer-Blinded Study
Single-injection pericapsular nerve group (PENG) block with ropivacaine provides clear analgesic effects in preoperative p...
A Decades-Long Journey of Palmitoylethanolamide (PEA) for Chronic Neuropathic Pain Management: A Comprehensive Narrative Review
A Decades-Long Journey of Palmitoylethanolamide (PEA) for Chronic Neuropathic Pain Management: A Comprehensive Narrative Review
Palmitoylethanolamide (PEA) has been prescribed in neuropathic pain management for over 20 years. This study aims...
The Global Burden of Migraine: A 30-Year Trend Review and Future Projections by Age, Sex, Country, and Region
The Global Burden of Migraine: A 30-Year Trend Review and Future Projections by Age, Sex, Country, and Region
Migraine is a prevalent neurological disorder causing significant disability worldwide. Despite extensive research on spec...
Ultrasound-Guided Thoracic Paravertebral Injection of Platelet-Rich Plasma for the Treatment of Thoracic Herpes Zoster-Related Pain: A Study Protocol
Ultrasound-Guided Thoracic Paravertebral Injection of Platelet-Rich Plasma for the Treatment of Thoracic Herpes Zoster-Related Pain: A Study Protocol
Herpes zoster (HZ), triggered by the reactivation of the varicella-zoster virus, manifests as a painful rash known as zost...
The Diagnosis and Management of Meralgia Paresthetica: A Narrative Review
The Diagnosis and Management of Meralgia Paresthetica: A Narrative Review
Meralgia paresthetica (MP) is a sensory mononeuropathy affecting the lateral femoral cutaneous nerve. Diagnosis is typical...
Complementary Approaches to Postoperative Pain Management: A Review of Non-pharmacological Interventions
Complementary Approaches to Postoperative Pain Management: A Review of Non-pharmacological Interventions
Postoperative pain significantly affects many surgical patients. While opioids are crucial for pain management, they come ...
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