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A new direction for adjunctive therapy of difficult-to-treat depression: examining the role of orexin receptor antagonists
A new direction for adjunctive therapy of difficult-to-treat depression: examining the role of orexin receptor antagonists
One of the several pressing unmet needs in the pharmacotherapy of MDD is development of drugs with novel mechanisms of act...
J-shaped association between the neutrophil percentage-to-albumin ratio (NPAR) and depression: analyses of NHANES 2005–2018
J-shaped association between the neutrophil percentage-to-albumin ratio (NPAR) and depression: analyses of NHANES 2005–2018
Inflammation is an essential driving factor in the development of depression, but the relationship between the composite i...
Associations of brain structure with psychopathy
Associations of brain structure with psychopathy
Psychopathy is one of the greatest risk factors for serious and persistent violence. In order to detect its neurobiologica...
Inflammatory ratios as predictors of length of hospitalization in psychiatric patients: A multicenter study
Inflammatory ratios as predictors of length of hospitalization in psychiatric patients: A multicenter study
Burgeoning evidence underscores the role of inflammation in psychiatric disorders where inflammation is linked to some cli...
Associations of cardiorespiratory fitness and muscular fitness with plasma levels of endocannabinoids and their analogues in adults with diagnosed depression: SONRIE study
Associations of cardiorespiratory fitness and muscular fitness with plasma levels of endocannabinoids and their analogues in adults with diagnosed depression: SONRIE study
Depression is a leading cause of global disability, affecting approximately 280 million individuals worldwide. Em...
Causal relationship between proton pump inhibitors and dementia risk: evidence from a Mendelian randomization study
Causal relationship between proton pump inhibitors and dementia risk: evidence from a Mendelian randomization study
This study aims to analyze the causal relationship between Proton Pump Inhibitors (PPI) and the risk of Dementia (DEM) usi...
The prevalence of internet addiction and its association with quality of life among inflight security officers based on a national survey: a network analysis perspective
The prevalence of internet addiction and its association with quality of life among inflight security officers based on a national survey: a network analysis perspective
Given the heavy responsibilities placed on inflight security officers (IFSO) to ensure passenger safety and eliminate infl...
Putamen subregion dysfunction mediates the relationship between childhood maltreatment and major depressive disorder
Putamen subregion dysfunction mediates the relationship between childhood maltreatment and major depressive disorder
Childhood maltreatment is a significant risk factor for the development of major depressive disorder (MDD) and is closely ...
Individualizing rTMS in treatment-resistant depression from patient-specific perfusion abnormalities a proof-of-concept randomized trial in comparison to standard rTMS and tDCS
Individualizing rTMS in treatment-resistant depression from patient-specific perfusion abnormalities a proof-of-concept randomized trial in comparison to standard rTMS and tDCS
Studies examining treatment-resistant depression (TRD) as a group implicitly assume that these conditions share similar pa...
Alterations of the endocannabinoid system in autism spectrum disorder: a systematic review and meta-analysis
Alterations of the endocannabinoid system in autism spectrum disorder: a systematic review and meta-analysis
Dysregulation of the endocannabinoid system (ECS) might be related to autism spectrum disorder (ASD). This study conducts ...
Decreased DTI-APLS correlated with cognitive impairment in veterans with post-traumatic stress disorder
Decreased DTI-APLS correlated with cognitive impairment in veterans with post-traumatic stress disorder
Post-traumatic stress disorder (PTSD) is a risk for cognitive impairment with underlying mechanism unresolved. Our study a...
Genetic insights into the effect of Metformin on psychiatry disorders
Genetic insights into the effect of Metformin on psychiatry disorders
This study employs Mendelian Randomization (MR) to explore the causal relationships between Metformin and 20 mental illnes...
Identification of overlapping genetic loci between inflammatory bowel disease and major depressive disorder
Identification of overlapping genetic loci between inflammatory bowel disease and major depressive disorder
Patients diagnosed with inflammatory bowel disease (IBD) are often observed to suffer from co-occurring major depressive d...
Abnormalities of gray matter volume and structural covariance in children with attention-deficit/hyperactivity disorder subtypes: implications for clinical correlations
Abnormalities of gray matter volume and structural covariance in children with attention-deficit/hyperactivity disorder subtypes: implications for clinical correlations
Attention deficit and hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder characterized by attention ...
Assessment of the bidirectional causal association between allergic diseases and neuropsychiatric disorders
Assessment of the bidirectional causal association between allergic diseases and neuropsychiatric disorders
This study aimed to explore the causal associations between allergic diseases and neuropsychiatric disorders via bidirecti...
Effectiveness of, access to and need for electroconvulsive therapy in forensic psychiatric hospitals: a survey in Germany and Switzerland
Effectiveness of, access to and need for electroconvulsive therapy in forensic psychiatric hospitals: a survey in Germany and Switzerland
Patients with treatment resistant schizophrenia (TRS) may benefit from electroconvulsive therapy (ECT). Although TRS is a ...
Influence of recent cannabis use on altered spectral entropy modulation and connectivity strength in patients with psychosis
Influence of recent cannabis use on altered spectral entropy modulation and connectivity strength in patients with psychosis
Cannabis use is highly prevalent in individuals with psychosis, raising concerns about its influence on brain function. El...
Identifying novel chemical-related susceptibility genes for five psychiatric disorders through integrating genome-wide association study and tissue-specific 3′aQTL annotation datasets
Identifying novel chemical-related susceptibility genes for five psychiatric disorders through integrating genome-wide association study and tissue-specific 3′aQTL annotation datasets
The establishment of 3ʹaQTLs comprehensive database provides an opportunity to help explore the functional interpreta...
Long-term follow-up of brain regional changes and the association with cognitive impairment in quarantined COVID-19 survivors
Long-term follow-up of brain regional changes and the association with cognitive impairment in quarantined COVID-19 survivors
This study aimed to evaluate the neuropsychiatric symptoms of quarantined COVID-19 survivors 15 months after disc...
Assessment of immunoprecipitation with subsequent immunoassays for the blood-based diagnosis of Alzheimer’s disease
Assessment of immunoprecipitation with subsequent immunoassays for the blood-based diagnosis of Alzheimer’s disease
The Aβ42/40 ratio and the concentration of phosphorylated Tau181 in blood plasma represent attractive biomarkers for ...
Hypothalamic subunit volumes and relations to violence and psychopathy in male offenders with or without a psychotic disorder
Hypothalamic subunit volumes and relations to violence and psychopathy in male offenders with or without a psychotic disorder
The hypothalamus is key to body homeostasis, including regulating cortisol, testosterone, vasopressin, and oxytocin hormon...
Self-reported interoception and exteroception are atypical and excessively coupled in psychosis compared to healthy controls
Self-reported interoception and exteroception are atypical and excessively coupled in psychosis compared to healthy controls
Although psychotic disorders are characterized by an impaired ability to discriminate internal and external worlds, the ro...
A clinical approach to the investigation and management of long COVID associated neuropathic pain
A clinical approach to the investigation and management of long COVID associated neuropathic pain
COVID–19 has been associated with a wide range of ongoing symptoms following recovery from the acute SARS-CoV-2 infe...
Global reward processing deficits predict negative symptoms transdiagnostically and transphasically in a severe mental illness-spectrum sample
Global reward processing deficits predict negative symptoms transdiagnostically and transphasically in a severe mental illness-spectrum sample
Reward processing impairments are a key factor associated with negative symptoms in those with severe mental illnesses. Ho...
Network structure of symptomatology of adult attention-deficit hyperactivity disorder in patients with mood disorders
Network structure of symptomatology of adult attention-deficit hyperactivity disorder in patients with mood disorders
Patients with mood disorders commonly manifest comorbid psychiatric disorders, including attention-deficit/hyperactivity d...
Parental marital status and anxiety symptoms in adolescents: the mediating effect of childhood maltreatment
Parental marital status and anxiety symptoms in adolescents: the mediating effect of childhood maltreatment
Although previous studies have established the association between parental marital status and mental health problems in a...
Effects of melancholic features on positive and negative suicidal ideation in patients with treatment-resistant depression and strong suicidal ideation receiving low-dose ketamine infusion
Effects of melancholic features on positive and negative suicidal ideation in patients with treatment-resistant depression and strong suicidal ideation receiving low-dose ketamine infusion
The role of melancholic features on the antisuicidal effect of 0.5 mg/kg ketamine infusion has remained unclear i...
All eyes on PCS: analysis of the retinal microvasculature in patients with post-COVID syndrome—study protocol of a 1 year prospective case–control study
All eyes on PCS: analysis of the retinal microvasculature in patients with post-COVID syndrome—study protocol of a 1 year prospective case–control study
Since widespread vaccination against COVID-19, the development of effective antiviral drugs, and the decreasing number of ...
Exploring specific associations of childhood maltreatment with social cognition in drug-naive first-episode major depressive disorder: a sex-centric approach
Exploring specific associations of childhood maltreatment with social cognition in drug-naive first-episode major depressive disorder: a sex-centric approach
Childhood maltreatment (CM) has been linked to social cognition deficits in major depressive disorder (MDD), but little is...
Clinical predictors of suicidal ideation, suicide attempts and suicide death in depressive disorder: a systematic review and meta-analysis
Clinical predictors of suicidal ideation, suicide attempts and suicide death in depressive disorder: a systematic review and meta-analysis
Patients with depressive disorders are especially prone to suicide risk. Among the clinical predictors of suicidality, tho...
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