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Neuroprognostication After Cardiac Arrest: From Test-Centered Prediction to Ethically Constrained, Longitudinal Decision-Making
Neuroprognostication After Cardiac Arrest: From Test-Centered Prediction to Ethically Constrained, Longitudinal Decision-Making
Neuroprognostication after cardiac arrest should not be understood as a conventional diagnostic exercise aimed at achievin...
Evaluation of a Novel Automated Cerebral Ventricular Drainage System for Intracranial Pressure Monitoring and Cerebrospinal Fluid Drainage in Neurocritical Care Patients: A Prospective, Randomized Clinical Study
Evaluation of a Novel Automated Cerebral Ventricular Drainage System for Intracranial Pressure Monitoring and Cerebrospinal Fluid Drainage in Neurocritical Care Patients: A Prospective, Randomized Clinical Study
Neurointensive care is moving toward more automated patient management. This study aimed to evaluate a novel external vent...
Valproic acid for the management of agitation in neurosurgical intensive care unit patients
Valproic acid for the management of agitation in neurosurgical intensive care unit patients
Neurosurgical patients are at an increased risk of developing agitation and intensive care unit (ICU) delirium due to dire...
A Novel Anti-Inflammatory Small Molecule MW189 Reduces Microglial Activation and Improves Functional Outcomes in a Murine Model of Subarachnoid Hemorrhage
A Novel Anti-Inflammatory Small Molecule MW189 Reduces Microglial Activation and Improves Functional Outcomes in a Murine Model of Subarachnoid Hemorrhage
Aneurysmal subarachnoid hemorrhage (SAH) is a devastating disease with significant neurological morbidity. In current prac...
Early Positive Fluid Balance as a Clinical Marker of Systemic Capillary Leak and Clazosentan Intolerance After Aneurysmal Subarachnoid Hemorrhage
Early Positive Fluid Balance as a Clinical Marker of Systemic Capillary Leak and Clazosentan Intolerance After Aneurysmal Subarachnoid Hemorrhage
Clazosentan, a selective endothelin A receptor antagonist, mitigates cerebral vasospasm following aneurysmal subarachnoid ...
Operator and Modality-Dependent Limitations of Optic Nerve Sheath Diameter Sonography for Raised ICP in TBI: A Meta-Regression of Diagnostic Accuracy
Operator and Modality-Dependent Limitations of Optic Nerve Sheath Diameter Sonography for Raised ICP in TBI: A Meta-Regression of Diagnostic Accuracy
Optic nerve sheath diameter (ONSD) sonography has been investigated as a noninvasive tool for detecting elevated intracran...
Subarachnoid Hemorrhage: Clazosentan vs. Fasudil for Vasospasm Prevention (SAVIOR) Study: Study Protocol for a Prospective, Multicenter, Randomized Trial
Subarachnoid Hemorrhage: Clazosentan vs. Fasudil for Vasospasm Prevention (SAVIOR) Study: Study Protocol for a Prospective, Multicenter, Randomized Trial
Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating condition, with cerebral vasospasm and subsequent delayed cereb...
Utilization of Noninvasive Intracranial Pressure Monitoring in Patients with Traumatic Brain Injury Treated in Low-Resource Settings: The Intrigo Study
Utilization of Noninvasive Intracranial Pressure Monitoring in Patients with Traumatic Brain Injury Treated in Low-Resource Settings: The Intrigo Study
Invasive intracranial pressure (ICP) monitoring is not universally available in low-resource settings, mainly owing to hig...
Combination of Albumin and Cilostazol Improves Outcomes in a Rodent Model of Aneurysmal Subarachnoid Hemorrhage
Combination of Albumin and Cilostazol Improves Outcomes in a Rodent Model of Aneurysmal Subarachnoid Hemorrhage
Patients recovering from aneurysmal subarachnoid hemorrhage (aSAH) often suffer secondary neurologic injury owing to delay...
Impact of FXIII Levels on Hematoma Expansion and Outcomes in Patients with Spontaneous Intracranial Hemorrhage: A Prospective Observational Cohort Study of 132 Patients
Impact of FXIII Levels on Hematoma Expansion and Outcomes in Patients with Spontaneous Intracranial Hemorrhage: A Prospective Observational Cohort Study of 132 Patients
Diminished levels of FXIII are significantly correlated with hematoma expansion (HE) and unfavorable clinical outcomes. Al...
Teleneurocritical Care (TeleNCC) Consensus Statement
Teleneurocritical Care (TeleNCC) Consensus Statement
Teleneurocritical care (TeleNCC) provides virtual neurocritical care in emergency departments and intensive care units tha...
Association of Location-Specific Perihematomal Edema with Clinical Outcomes in Deep Intracerebral Hemorrhage
Association of Location-Specific Perihematomal Edema with Clinical Outcomes in Deep Intracerebral Hemorrhage
Perihematomal edema (PHE) represents a major secondary injury mechanism following intracerebral hemorrhage (ICH). This stu...
Delirium in Children Hospitalized with Acute COVID-19 or MIS-C: Secondary Analysis of the 2020–2021 Global Consortium Study of Neurologic Dysfunction in COVID-19
Delirium in Children Hospitalized with Acute COVID-19 or MIS-C: Secondary Analysis of the 2020–2021 Global Consortium Study of Neurologic Dysfunction in COVID-19
The aims of this study were to describe pediatric delirium and its association with inflammatory, neurodiagnostic, and cli...
AI Models for Surgical Decision Support in Spontaneous Intracerebral Hemorrhage: A Systematic Review in Relation to Trials and Guidelines
AI Models for Surgical Decision Support in Spontaneous Intracerebral Hemorrhage: A Systematic Review in Relation to Trials and Guidelines
Artificial intelligence (AI) applications for spontaneous intracerebral hemorrhage (ICH) are rapidly expanding, particular...
Guidelines for Neuroprognostication in Critically ill Adults with Acute Ischemic Stroke
Guidelines for Neuroprognostication in Critically ill Adults with Acute Ischemic Stroke
Patients with acute ischemic stroke (AIS) may require intensive care unit admission for several reasons, including post-pr...
Pulsatility Index Measurement via the Submandibular Internal Carotid Artery: An Alternative to Transcranial Assessment
Pulsatility Index Measurement via the Submandibular Internal Carotid Artery: An Alternative to Transcranial Assessment
Pulsatility index (PI) measurements using transcranial color flow imaging via the temporal bone are one of the clinical su...
Inflammation as a Source of Cardiac Injury After Subarachnoid Hemorrhage
Inflammation as a Source of Cardiac Injury After Subarachnoid Hemorrhage
Cardiac injury commonly occurs in patients after a cerebrovascular event, but it is n...
The Role of Serum Monocytes and Tissue Macrophages in Driving Left Ventricular Systolic Dysfunction and Cardiac Inflammation Following Subarachnoid Hemorrhage
The Role of Serum Monocytes and Tissue Macrophages in Driving Left Ventricular Systolic Dysfunction and Cardiac Inflammation Following Subarachnoid Hemorrhage
Neurocardiogenic injury is common after aneurysmal subarachnoid hemorrhage (aSAH) despite low prevalence of preexisting ca...
Multiorgan Dysfunction Syndrome in Abusive and Accidental Pediatric Traumatic Brain Injury
Multiorgan Dysfunction Syndrome in Abusive and Accidental Pediatric Traumatic Brain Injury
Abusive head trauma (AHT) is a mechanism of pediatric traumatic brain injury (TBI) with high morbidity and mortality. Mult...
Clinical Outcomes and Systemic Complications Related to the Severity and Etiology of Status Epilepticus Using a Common Data Model
Clinical Outcomes and Systemic Complications Related to the Severity and Etiology of Status Epilepticus Using a Common Data Model
Status epilepticus (SE) is a critical neurological emergency in patients with neurological and nonneurological diseases. M...
Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group in the Pediatric Population
Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group in the Pediatric Population
The fundamental gap obstructing forward progress of evidenced-based care in pediatric and neonatal disorders of consciousn...
Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Physiology and Big Data
Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Physiology and Big Data
The Curing Coma Campaign Collaborators are listed in the Supplementary Appendix. The Curing Coma Campaign and its Contribu...
A Proposal for a New Protocol for Sonographic Assessment of the Optic Nerve Sheath Diameter: The CLOSED Protocol
A Proposal for a New Protocol for Sonographic Assessment of the Optic Nerve Sheath Diameter: The CLOSED Protocol
Aspide R, Bertolini G, Albini Riccioli L, Mazzatenta D, Palandri G, Biasucci DG. A proposal for a new protocol for sonogra...
Response to Letter to Editor on “A Proposal for a New Protocol for Sonographic Assessment of the Optic Nerve Sheath Diameter: The CLOSED Protocol”
Response to Letter to Editor on “A Proposal for a New Protocol for Sonographic Assessment of the Optic Nerve Sheath Diameter: The CLOSED Protocol”
Publisher's NoteSpringer Nature remains neutral with regard to jurisdictional claims in published maps and institutional a...
The State of the Field of Pediatric Multimodality Neuromonitoring
The State of the Field of Pediatric Multimodality Neuromonitoring
The use of multimodal neuromonitoring in pediatrics is in its infancy relative to adult neurocritical care. Multimodal neu...
Overlapping Physiologic Signs of Sepsis and Paroxysmal Sympathetic Hyperactivity After Traumatic Brain Injury: Exploring A Clinical Conundrum
Overlapping Physiologic Signs of Sepsis and Paroxysmal Sympathetic Hyperactivity After Traumatic Brain Injury: Exploring A Clinical Conundrum
Paroxysmal sympathetic hyperactivity (PSH) occurs in a subset of patients with traumatic brain injury (TBI) and is associa...
Perspectives of Medical Organizations, Organ Procurement Organizations, and Advocacy Organizations About Revising the Uniform Determination of Death Act (UDDA)
Perspectives of Medical Organizations, Organ Procurement Organizations, and Advocacy Organizations About Revising the Uniform Determination of Death Act (UDDA)
The Uniform Law Commission paused work of the Drafting Committee to Revise the Uniform Determination of Death Act (UDDA) i...
Ketamine for Status Epilepticus in Children: Searching for the Right Drug for the Right Patient
Ketamine for Status Epilepticus in Children: Searching for the Right Drug for the Right Patient
Pediatric convulsive status epilepticus has a yearly incidence of ~ 20/100,000 in...
Clinical Trial Protocol for BEACH: A Phase 2a Study of MW189 in Patients with Acute Nontraumatic Intracerebral Hemorrhage
Clinical Trial Protocol for BEACH: A Phase 2a Study of MW189 in Patients with Acute Nontraumatic Intracerebral Hemorrhage
Patients with acute spontaneous intracerebral hemorrhage (ICH) develop secondary neuroinflammation and cerebral edema that...
Burst Suppression as a Treatment Goal in Refractory Status Epilepticus
Burst Suppression as a Treatment Goal in Refractory Status Epilepticus
The use of burst suppression has long been considered a therapeutic goal in the manag...
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