Baeza FL, da Rocha NS, Fleck MP (2018) Predictors of length of stay in an acute psychiatric inpatient facility in a general hospital: a prospective study. Brazilian J Psychiatry;40

Ride J, Kasteridis P, Gutacker N, Aragon Aragon MJ, Jacobs R (2020) Healthcare costs for people with serious mental illness in England: an analysis of costs across primary care, hospital care, and specialist mental healthcare. Appl Health Econ Health Policy 2020/04/01(2):177–188

Article  Google Scholar 

Johnstone P, Zolese G (1999) Systematic review of the effectiveness of planned short hospital stays for mental health care. BMJ 318(7195):1387–1390

Article  CAS  PubMed  PubMed Central  Google Scholar 

NHS Mental Health Implementation Plan 2019/20–2023/24. NHS England. Available at: https://www.longtermplan.nhs.uk/wp-content/uploads/2019/07/nhs-mental-health-implementation-plan-2019-20-2023-24.pdf

Mondelli V, Dazzan P, Pariante CM (2015) Immune abnormalities across psychiatric disorders: clinical relevance. BJPsych Adv 21(3):150–156

Article  Google Scholar 

Bauer ME, Teixeira AL (2019) Inflammation in psychiatric disorders: what comes first? Ann N Y Acad Sci 1437(1):57–67

Article  CAS  PubMed  Google Scholar 

Muneer A (2016) Bipolar disorder: role of inflammation and the development of disease biomarkers. Psychiatry Invest 13(1):18

Article  CAS  Google Scholar 

Müller N (2018) Inflammation in schizophrenia: pathogenetic aspects and therapeutic considerations. Schizophr Bull 44(5):973–982

Article  PubMed  PubMed Central  Google Scholar 

Maes M, Chiavetto LB, Bignotti S et al (2000) Effects of atypical antipsychotics on the inflammatory response system in schizophrenic patients resistant to treatment with typical neuroleptics. Eur Neuropsychopharmacol 10(2):119–124

Article  CAS  PubMed  Google Scholar 

Hannestad J, DellaGioia N, Bloch M (2011) The effect of antidepressant medication treatment on serum levels of inflammatory cytokines: a meta-analysis. Neuropsychopharmacology 36(12):2452–2459

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kopschina Feltes P, Doorduin J, Klein HC, Juárez-Orozco LE, Dierckx RA, Moriguchi-Jeckel CM, de Vries EF (2017) Anti-inflammatory treatment for major depressive disorder: implications for patients with an elevated immune profile and non-responders to standard antidepressant therapy. J Psychopharmacol 31(9):1149–1165

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kappelmann N, Lewis G, Dantzer R, Jones P, Khandaker G (2018) Antidepressant activity of anti-cytokine treatment: a systematic review and meta-analysis of clinical trials of chronic inflammatory conditions. Mol Psychiatry 23(2):335–343

Article  CAS  PubMed  Google Scholar 

Miller BJ, Buckley P, Seabolt W, Mellor A, Kirkpatrick B (2011) Meta-analysis of cytokine alterations in schizophrenia: clinical status and antipsychotic effects. Biol Psychiatry 70(7):663–671

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rosenblat JD, McIntyre RS (2017) Bipolar disorder and immune dysfunction: epidemiological findings, proposed pathophysiology and clinical implications. Brain Sci 7(11):144

Article  PubMed  PubMed Central  Google Scholar 

Pantelis C, Papadimitriou GN, Papiol S et al (2014) Biological insights from 108 schizophrenia-associated genetic loci. Nature 511(7510):421–427

Article  PubMed Central  Google Scholar 

Sun J, Wang W, Zhang R, Duan H, Tian X, Xu C, Li X, Zhang D (2022) Multivariate genome-wide association study of depression, cognition, and memory phenotypes and validation analysis identify 12 cross-ethnic variants. Translational Psychiatry 2022/07/30 12(1):304

Article  CAS  Google Scholar 

Baumeister D, Russell A, Pariante CM, Mondelli V (2014) Inflammatory biomarker profiles of mental disorders and their relation to clinical, social and lifestyle factors. Soc Psychiatry Psychiatr Epidemiol Jun 49(6):841–849

Article  Google Scholar 

Kose M, Pariante CM, Dazzan P, Mondelli V (2021) The role of peripheral inflammation in clinical outcome and brain imaging abnormalities in psychosis: A systematic review. Front Psychiatry 12:612471

Article  PubMed  PubMed Central  Google Scholar 

Cheng Y, Wang Y, Wang X, Jiang Z, Zhu L, Fang S (2022) Neutrophil-to-Lymphocyte ratio, Platelet-to-Lymphocyte ratio, and Monocyte-to-Lymphocyte ratio in depression: an updated systematic review and Meta-Analysis. Front Psychiatry 13:893097

Article  PubMed  PubMed Central  Google Scholar 

Mazza MG, Lucchi S, Rossetti A, Clerici M (2020) Neutrophil-lymphocyte ratio, monocyte-lymphocyte ratio and platelet-lymphocyte ratio in non-affective psychosis: A meta-analysis and systematic review. World J Biol Psychiatry Jun 21(5):326–338

Article  Google Scholar 

Mazza MG, Lucchi S, Tringali AGM, Rossetti A, Botti ER, Clerici M (2018) Neutrophil/lymphocyte ratio and platelet/lymphocyte ratio in mood disorders: A meta-analysis. Prog Neuropsychopharmacol Biol Psychiatry 2018/06/(08/):84:229–236

Article  Google Scholar 

Kim HW, Lee J-c, Paik K-h, Kang J, Kim J, Hwang J-H (2017) Serum interleukin-6 is associated with pancreatic ductal adenocarcinoma progression pattern. Medicine 96(5):e5926

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chandrashekara S, Mukhtar Ahmad M, Renuka P, Anupama K, Renuka K (2017) Characterization of neutrophil-to‐lymphocyte ratio as a measure of inflammation in rheumatoid arthritis. Int J Rheum Dis 20(10):1457–1467

Article  CAS  PubMed  Google Scholar 

Karageorgiou V, Milas GP, Michopoulos I (2019) Neutrophil-to-lymphocyte ratio in schizophrenia: A systematic review and meta-analysis. Schizophrenia Research 2019/04/01/ 206:4–12

Article  Google Scholar 

Yang Z, Zhang Z, Lin F, Ren Y, Liu D, Zhong R, Liang Y (2017) Comparisons of neutrophil-, monocyte‐, eosinophil‐, and basophil‐lymphocyte ratios among various systemic autoimmune rheumatic diseases. Apmis 125(10):863–871

Article  CAS  PubMed  Google Scholar 

Li D-Y, Hao X-Y, Ma T-M, Dai H-X, Song Y-S (2017) The prognostic value of platelet-to-lymphocyte ratio in urological cancers: a meta-analysis. Sci Rep 7(1):15387

Article  PubMed  PubMed Central  Google Scholar 

Li H, Zhou Y, Ma Y, Han S, Zhou L (2017) The prognostic value of the platelet-to-lymphocyte ratio in acute coronary syndrome: a systematic review and meta-analysis. Pol Heart J (Kardiologia Polska) 75(7):666–673

Article  Google Scholar 

Bhikram T, Sandor P (2022) Neutrophil-lymphocyte ratios as inflammatory biomarkers in psychiatric patients. Brain Behav Immun Oct 105:237–246

Article  CAS  Google Scholar 

Özdin S, Böke Ö (2019) Neutrophil/lymphocyte, platelet/lymphocyte and monocyte/lymphocyte ratios in different stages of schizophrenia. Psychiatry Res Jan 271:131–135

Article  Google Scholar 

Llorca-Bofí V, Bioque M, Font M, Gich I, Mur M (2023) Correlation between C-reactive protein and the inflammatory ratios in acute schizophrenia inpatients: are they associated? J Psychiatr Res 165:191–196

Article  PubMed  Google Scholar 

Demircan F, Gözel N, Kılınç F, Ulu R, Atmaca M (2016) The impact of red blood cell distribution width and neutrophil/lymphocyte ratio on the diagnosis of major depressive disorder. Neurol Therapy 5:27–33

Article  Google Scholar 

Kayhan F, Gündüz Ş, Ersoy SA, Kandeğer A, Annagür BB (2017) Relationships of neutrophil–lymphocyte and platelet–lymphocyte ratios with the severity of major depression. Psychiatry Research 2017/01/01/ 247:332–335

Article  Google Scholar 

Arabska J, Łucka A, Magierski R, Sobów T, Wysokiński A (2018) Neutrophil-lymphocyte ratio is increased in elderly patients with first episode depression, but not in recurrent depression. Psychiatry Res 2018/05/01:263:35–40

Article  Google Scholar 

Velasco Á, Rodríguez-Revuelta J, Olié E et al (2020) Neutrophil-to-lymphocyte ratio: A potential new peripheral biomarker of suicidal behavior. Eur Psychiatry Feb 17(1):e14

Article  Google Scholar 

Aydin Sunbul E, Sunbul M, Yanartas O, Cengiz F, Bozbay M, Sari I, Gulec H (2016) Increased neutrophil/lymphocyte ratio in patients with depression is correlated with the severity of depression and cardiovascular risk factors. Psychiatry Investig Jan 13(1):121–126

Article  Google Scholar 

Kucukkarapinar M, Erbil D, Keles İ, Karadag F (2024) Association between mood disorder severity, treatment response and systemic inflammatory markers: exploring the role of NLR, PLR, MLR, and SII. Psychiatry Clin Psychopharmacol Mar 34(1):19–28