Preoperative Analgesia Efficacy of Liposomal Bupivacaine Following Pericapsular Nerve Group (PENG) Block in Patients with Hip Fracture: A Randomized Controlled Observer-Blinded Study

Nguyen MH, Lui SK. Holistic management of older patients with hip fractures. Orthop Nurs. 2020;39(3):183–91.

Article  PubMed  Google Scholar 

Kobayashi T, Ureshino H, Morimoto T, Sonohata M, Mawatari M. Pain relief differentiated according to the length of time that preoperative skin traction was carried out for hip fractures: a systematic review and meta-analysis. Int J Orthop Trauma Nurs. 2021;43: 100886.

Article  PubMed  Google Scholar 

Chaudhary K, Bose N, Tanna D, Chandnani A. Ultrasound-guided pericapsular nerve group (PENG) block versus femoral nerve block for positioning during spinal anaesthesia in proximal femur fractures: a randomised comparative study. Indian J Anaesth. 2023;67(10):913–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Simić A, Nesek Adam V, Rošić D, Kočet N, Svetec M, Herceg A, et al. Peripheral nerve blocks for hip fractures in emergency medicine. Acta Clin Croat. 2022;61(Suppl 1):78–83.

PubMed  PubMed Central  Google Scholar 

Fontes GM, Perez MV, Miashiro EH, Neto AIS, Grigio TR, Rodrigues LHS. Pericapsular hip block guided by ultrasonography in elderly people with hip fracture in the emergency sector: clinical trial. Revista Brasileira de Ortopedia. 2024;59(2):e284–96.

PubMed  PubMed Central  Google Scholar 

Gao Z, Xiao Y, Wang Q, Li Y. Comparison of dexmedetomidine and dexamethasone as adjuvant for ropivacaine in ultrasound-guided erector spinae plane block for video-assisted thoracoscopic lobectomy surgery: a randomized, double-blind, placebo-controlled trial. Ann Transl Med. 2019;7(22):668.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Verbeek T, Adhikary S, Urman R, Liu H. The application of fascia iliaca compartment block for acute pain control of hip fracture and surgery. Curr Pain Headache Rep. 2021;25(4):22.

Article  PubMed  Google Scholar 

Chughtai M, Sultan AA, Hudson B, Goodwin RC, Seif J, Khlopas A, et al. Liposomal bupivacaine is both safe and effective in controlling postoperative pain after spinal surgery in children: a controlled cohort study. Clin Spine Surg. 2020;33(10):e533–8.

Article  PubMed  Google Scholar 

Alexander JC, Sunna M, Goldenmerry Y, Mootz A, O’Connor C, Ringqvist J, et al. Comparison of transversus abdominis plane blocks with liposomal bupivacaine versus ropivacaine in open total abdominal hysterectomy. Proc (Bayl Univ Med Cent). 2022;35(6):746–50.

PubMed  Google Scholar 

Solis-Pazmino P, Figueroa L, La K, Termeie O, Oka K, Schleicher M, et al. Liposomal bupivacaine versus conventional anesthetic or placebo for hemorrhoidectomy: a systematic review and meta-analysis. Tech Coloproctol. 2024;28(1):29.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Salgado-García D, Díaz-Álvarez A, González-Rodríguez JL, López-Iglesias MR, Sánchez-López E, Sánchez-Ledesma MJ, et al. Comparison of the analgesic efficacy between levobupivacaine 0.25% and ropivacaine 0.375% for PENG (pericapsular nerve group) block in the context of hip fracture surgery of elderly patients: a single-center, randomized, and controlled clinical trial. J Clin Med. 2024;13(3):770.

Article  PubMed  PubMed Central  Google Scholar 

Lin X, Liu CW, Goh QY, Sim EY, Chan SKT, Lim ZW, et al. Pericapsular nerve group (PENG) block for early pain management of elderly patients with hip fracture: a single-center double-blind randomized controlled trial. Reg Anesth Pain Med. 2023;48(11):535–9.

Article  PubMed  Google Scholar 

Ma Y, Wu J, Xue J, Lan F, Wang T. Ultrasound-guided continuous fascia iliaca compartment block for pre-operative pain control in very elderly patients with hip fracture: a randomized controlled trial. Exp Ther Med. 2018;16(3):1944–52.

PubMed  PubMed Central  Google Scholar 

Li Q, Liao Y, Wang X, Zhan M, Xiao L, Chen Y. Efficacy of bilateral catheter superficial parasternal intercostal plane blocks using programmed intermittent bolus for opioid-sparing postoperative analgesia in cardiac surgery with sternotomy: a randomized, double-blind, placebo-controlled trial. J Clin Anesth. 2024;95: 111430.

Article  PubMed  Google Scholar 

Zhang T, Zhang T, Niu X, Li L, Gu J, Chen M, et al. Femoral nerve block using lower concentration ropivacaine preserves quadriceps strength while providing similar analgesic effects after knee arthroscopy. Knee Surg Sports Traumatol Arthrosc. 2023;31(11):4988–95.

Article  PubMed  PubMed Central  Google Scholar 

Girón-Arango L, Peng PWH, Chin KJ, Brull R, Perlas A. Pericapsular nerve group (PENG) block for hip fracture. Reg Anesth Pain Med. 2018;43(8):859–63.

PubMed  Google Scholar 

Hashmi J, Cusack B, Hughes L, Singh V, Srinivasan K. Transmuscular quadratus lumborum block versus infrainguinal fascia iliaca nerve block for patients undergoing elective hip replacement: a double-blinded, pilot, randomized controlled trial. Local Reg Anesth. 2022;15:45–55.

Article  PubMed  PubMed Central  Google Scholar 

Farrar JT, Berlin JA, Strom BL. Clinically important changes in acute pain outcome measures: a validation study. J Pain Symptom Manag. 2003;25(5):406–11.

Article  Google Scholar 

Acharya U, Lamsal R. Pericapsular nerve group block: an excellent option for analgesia for positional pain in hip fractures. Case Rep Anesthesiol. 2020;2020:1830136.

PubMed  PubMed Central  Google Scholar 

Pascarella G, Costa F, Del Buono R, Pulitanò R, Strumia A, Piliego C, et al. Impact of the pericapsular nerve group (PENG) block on postoperative analgesia and functional recovery following total hip arthroplasty: a randomised, observer-masked, controlled trial. Anaesthesia. 2021;76(11):1492–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang Y, Jiang Q, Long H, Chen H, Wei J, Li X, et al. Trends and benefits of early hip arthroplasty for femoral neck fracture in China: a national cohort study. Int J Surg. 2024;110(3):1347–55.

Article  PubMed  PubMed Central  Google Scholar 

Aliste J, Layera S, Bravo D, Jara Á, Muñoz G, Barrientos C, et al. Randomized comparison between pericapsular nerve group (PENG) block and suprainguinal fascia iliaca block for total hip arthroplasty. Reg Anesth Pain Med. 2021;46(10):874–8.

Article  PubMed  Google Scholar 

Mosaffa F, Taheri M, Manafi Rasi A, Samadpour H, Memary E, Mirkheshti A. Comparison of pericapsular nerve group (PENG) block with fascia iliaca compartment block (FICB) for pain control in hip fractures: a double-blind prospective randomized controlled clinical trial. Orthop Traumatol Surg Res. 2022;108(1): 103135.

Article  PubMed  Google Scholar 

Purcell RL, Brooks DI, Steelman TJ, Christensen DL, Dickens JF, Kent ML, et al. Fascia iliaca blockade with the addition of liposomal bupivacaine versus plain bupivacaine for perioperative pain management during hip arthroscopy: a double-blinded prospective randomized control trial. Arthroscopy. 2019;35(9):2608–16.

Article  PubMed  Google Scholar 

Schubert AK, Wiesmann T, Dinges HC. Measures to prolong duration of sensory block after regional anaesthesia. Curr Opin Anaesthesiol. 2023;36(1):103–8.

Article  PubMed  Google Scholar 

Feng CD, Xu Y, Chen S, Song N, Meng XW, Liu H, et al. Opioid-free anaesthesia reduces postoperative nausea and vomiting after thoracoscopic lung resection: a randomised controlled trial. Br J Anaesth. 2024;132(2):267–76.

Article  CAS  PubMed  Google Scholar 

Huda AU, Ghafoor H. The use of pericapsular nerve group (PENG) block in hip surgeries is associated with a reduction in opioid consumption, less motor block, and better patient satisfaction: a meta-analysis. Cureus. 2022;14(9): e28872.

PubMed  PubMed Central  Google Scholar 

Ma TT, Wang YH, Jiang YF, Peng CB, Yan C, Liu ZG, et al. Liposomal bupivacaine versus traditional bupivacaine for pain control after total hip arthroplasty: a meta-analysis. Medicine (Baltimore). 2017;96(25): e7190.

Article  CAS  PubMed  Google Scholar 

Gailey AD, Ostrum RF. The use of liposomal bupivacaine in fracture surgery: a review. J Orthop Surg Res. 2023;18(1):267.

Article  PubMed  PubMed Central  Google Scholar 

Dada O, Gonzalez Zacarias A, Ongaigui C, Echeverria-Villalobos M, Kushelev M, Bergese SD, et al. Does rebound pain after peripheral nerve block for orthopedic surgery impact postoperative analgesia and opioid consumption? A narrative review. Int J Environ Res Public Health. 2019;16(18):3257.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gadsden J, Long WJ. Time to analgesia onset and pharmacokinetics after separate and combined administration of liposome bupivacaine and bupivacaine HCl: considerations for clinicians. Open Orthop J. 2016;10:94–104.

Article  PubMed  PubMed Central  Google Scholar 

Comments (0)

No login
gif