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Integrative multi-layer genetic analysis identifies novel susceptibility genes for urolithiasis
Integrative multi-layer genetic analysis identifies novel susceptibility genes for urolithiasis
Urolithiasis is a complex disease influenced by genetic and metabolic factors. Although genome-wide association studies (G...
Proteomic analysis of stone-containing and non-stone human renal papillae reveals novel insights and therapeutic targets
Proteomic analysis of stone-containing and non-stone human renal papillae reveals novel insights and therapeutic targets
Nephrolithiasis is a highly prevalent urological condition with a marked recurrence tendency. However, the molecular mecha...
Determinants of treatment pathway in renal colic: a size-stratified analysis from the emergency department of a tertiary center
Determinants of treatment pathway in renal colic: a size-stratified analysis from the emergency department of a tertiary center
Acute flank pain due to ureteral calculi is a common presentation in emergency departments (EDs). Decisions between conser...
The development and internal validation of a rating scale system in predicting renal stone bacteria culture positivity before PCNL: a cross-sectional study
The development and internal validation of a rating scale system in predicting renal stone bacteria culture positivity before PCNL: a cross-sectional study
Targeted preoperative antibiotic therapy can help reduce infections following percutaneous nephrolithotomy (PCNL), but it ...
Development and validation of a novel in vitro porcine model for impacted ureteral stones based on objective pressure gradient assessment
Development and validation of a novel in vitro porcine model for impacted ureteral stones based on objective pressure gradient assessment
To establish and validate an isolated model of upper impacted ureteral stone(IUS) in pigs for clinical research on this co...
Equal-power Ho:YAG laser energy–frequency modulation during RIRS for renal pelvis stones: 0.3 J × 50 Hz vs. 1.5 J × 10 Hz
Equal-power Ho:YAG laser energy–frequency modulation during RIRS for renal pelvis stones: 0.3 J × 50 Hz vs. 1.5 J × 10 Hz
To compare outcomes of two holmium: yttrium–aluminum–garnet (Ho:YAG) laser energy–frequency protocols de...
Comparative evaluation of temperature generation during laser lithotripsy: thulium fiber laser, pulsed thulium: YAG, and holmium: YAG with pulse modulation in an ex vivo porcine kidney model
Comparative evaluation of temperature generation during laser lithotripsy: thulium fiber laser, pulsed thulium: YAG, and holmium: YAG with pulse modulation in an ex vivo porcine kidney model
Ureteroscopic laser lithotripsy results in heat generation, raising concern for thermal injury. As laser platforms evolve,...
Paeoniflorin alleviates nephrolithiasis by targeting serpine1 and inhibiting the NF-κB signaling pathway
Paeoniflorin alleviates nephrolithiasis by targeting serpine1 and inhibiting the NF-κB signaling pathway
Paeoniflorin (PF) is a bioactive monoterpene glycoside with well-established anti-inflammatory properties; however, its th...
Intrarenal pressure response to suction during ureteroscopy with a flexible and navigable suction sheath: in vivo porcine studies
Intrarenal pressure response to suction during ureteroscopy with a flexible and navigable suction sheath: in vivo porcine studies
Use of flexible and navigable suction ureteral access sheaths (FANS) can improve stone clearance during ureteroscopy but a...
Optimal thulium fiber laser parameters for non-impacted stone lithotripsy: an in-vitro and ex-vivo evaluation
Optimal thulium fiber laser parameters for non-impacted stone lithotripsy: an in-vitro and ex-vivo evaluation
Optimal parameter settings for thulium fiber laser (TFL) lithotripsy remain controversial, particularly regarding the bala...
A computational model for predicting shock in patients at risk of urosepsis after urolithiasis surgery
A computational model for predicting shock in patients at risk of urosepsis after urolithiasis surgery
To develop and validate an artificial intelligence model for predicting septic shock risk in urosepsis patients following ...
The anatomy of a jackstone: a novel morphometric analysis of a rare urinary calculus
The anatomy of a jackstone: a novel morphometric analysis of a rare urinary calculus
Jackstone calculi are rare urinary stones characterized by multiple spiculated arms, yet the mechanisms underlying their d...
Impact of sampaio pelvicalyceal system variants on the clinical and surgical outcomes of supine mini-percutaneous nephrolithotomy in adults
Impact of sampaio pelvicalyceal system variants on the clinical and surgical outcomes of supine mini-percutaneous nephrolithotomy in adults
Certain anatomical subtypes are associated with more favorable surgical outcomes, highlighting the importance of routine p...
Fiber-to-stone distance and fragment size with holmium laser lithotripsy
Fiber-to-stone distance and fragment size with holmium laser lithotripsy
Control of fragment size during laser lithotripsy has taken on increasing importance with adoption of ureteroscopic aspira...
Based on network pharmacology, the mechanism of Dioscin in alleviating renal tubular epithelial cell injury induced by calcium oxalate crystals was explored
Based on network pharmacology, the mechanism of Dioscin in alleviating renal tubular epithelial cell injury induced by calcium oxalate crystals was explored
The commencement of kidney stone formation involves a crucial initial phase characterized by injury to renal tubular cells...
Annexin-derived self-assembling peptide nanostructures for alleviation of calcium oxalate -induced renal injury
Annexin-derived self-assembling peptide nanostructures for alleviation of calcium oxalate -induced renal injury
The formation of polycrystalline aggregates in the glomerulus or other components of the urinary system is indisputably th...
A mouse model for the study of diet-induced changes in intestinal microbiome composition on renal calcium oxalate crystal formation
A mouse model for the study of diet-induced changes in intestinal microbiome composition on renal calcium oxalate crystal formation
Currently available animal models for calcium oxalate kidney stones are limited in their translational potential. Particul...
Identification of potential pathogenic genes for urolithiasis through multi-omics Mendelian randomization analysis
Identification of potential pathogenic genes for urolithiasis through multi-omics Mendelian randomization analysis
Urolithiasis, a common urological disorder affecting about 10% of the global population, is known for its high recurrence ...
The effect of training given to patients who underwent ureteroscopy with double-J stent placement on anxiety before and after surgery and readiness for discharge
The effect of training given to patients who underwent ureteroscopy with double-J stent placement on anxiety before and after surgery and readiness for discharge
Patient education is effective in reducing the level of anxiety before and after surgery and increasing the level of readi...
The impact of Mayo Adhesion probability score on the success of extracorporeal shock wave lithotripsy for kidney stones
The impact of Mayo Adhesion probability score on the success of extracorporeal shock wave lithotripsy for kidney stones
Urolithiasis is a prevalent condition in urology, with extracorporeal shock wave lithotripsy (ESWL) serving as a common tr...
Whole exome sequencing reveals heparan sulfate proteoglycan 2 (HSPG2) as a potential causative gene for kidney stone disease in a Thai family
Whole exome sequencing reveals heparan sulfate proteoglycan 2 (HSPG2) as a potential causative gene for kidney stone disease in a Thai family
Kidney stone disease (KSD) is a prevalent and complex condition, with an incidence of 85 cases per 100,000 individuals in ...
Analysis of risk factors for SIRS after PCNL in patients with solitary kidney
Analysis of risk factors for SIRS after PCNL in patients with solitary kidney
The purpose of this study is to address the gap in the existing literature regarding the risk factors for systemic inflamm...
Matched pair analysis of wide versus narrow focus during shockwave lithotripsy for urolithiasis
Matched pair analysis of wide versus narrow focus during shockwave lithotripsy for urolithiasis
To compare stone clearance and complications between a ‘wide’ (9 × 50 mm) and ‘...
Harnessing magnetism: evaluation of safety, tolerance and feasibility of magnetic kidney stone retrieval in vivo in porcine models
Harnessing magnetism: evaluation of safety, tolerance and feasibility of magnetic kidney stone retrieval in vivo in porcine models
The primary objective of urolithiasis therapy is complete stone removal and highest stone-clearance rates possible to mini...
Innovative use of the new pulsed-thulium: YAG laser for ureteroscopic lithotripsy: can the “kidney stone calculator” predict lithotripsy duration?
Innovative use of the new pulsed-thulium: YAG laser for ureteroscopic lithotripsy: can the “kidney stone calculator” predict lithotripsy duration?
To assess the accuracy of Kidney Stone Calculator(KSC), a software designed for surgical planning, in predicting the durat...
Prolyl hydroxylase domain inhibitors prevent kidney crystal formation by suppressing inflammation
Prolyl hydroxylase domain inhibitors prevent kidney crystal formation by suppressing inflammation
The early stages of kidney crystal formation involve inflammation and hypoxia-induced cell injury; however, the role of th...
Comparison of flexible and navigable suction ureteral access sheath with conventional ureteral access sheath for pediatric retrograde intrarenal surgery: a single-center propensity-matched analysis
Comparison of flexible and navigable suction ureteral access sheath with conventional ureteral access sheath for pediatric retrograde intrarenal surgery: a single-center propensity-matched analysis
The flexible and navigable suction ureteral access sheath (FANS-UAS) has increasingly been recognized as a potential game ...
Enhancing lithotripsy efficiency in retrograde intrarenal surgery via a flexible kidney-fixed position: findings from a prospective cohort study
Enhancing lithotripsy efficiency in retrograde intrarenal surgery via a flexible kidney-fixed position: findings from a prospective cohort study
Retrograde intrarenal surgery (RIRS) is recognized as an effective intervention for renal stones measuring less than 20&am...
Evaluating postoperative complications in standard percutaneous nephrolithotomy for renal stones larger than 2 cm: a retrospective study utilizing the E-PASS scoring system
Evaluating postoperative complications in standard percutaneous nephrolithotomy for renal stones larger than 2 cm: a retrospective study utilizing the E-PASS scoring system
Percutaneous nephrolithotomy (PCNL) is a widely preferred method for treating complex kidney stones, particularly in patie...
Performance of brushite plaster as kidney stone phantoms for laser lithotripsy
Performance of brushite plaster as kidney stone phantoms for laser lithotripsy
Artificial phantoms used in photothermal near-infrared laser lithotripsy research generally fail to mimic both the chemica...
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