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Green nephrology: from evidence to action
In the past 20 years, awareness of the huge environmental impact of kidney care has increased considerably. Although oppor...
Physical activity in kidney disease: evidence and implementation
Physical activity in kidney disease: evidence and implementation
Despite over 30 years of research and guidelines promoting physical activity for people living with chronic kidney disease...
Guidelines for the use of economic evaluation to inform policies around access to treatment for kidney failure
Guidelines for the use of economic evaluation to inform policies around access to treatment for kidney failure
Kidney failure is the most advanced stage of chronic kidney disease, at which point patients require kidney replacement th...
The changing landscape of kidney health and disease in Africa
Africa has a high prevalence of chronic kidney disease (CKD), but efforts to address this burden lag behind those of high-...
Two decades of nephrology research: progress and future challenges
Since publication of the first issue of Nature Reviews Nephrology 20 years ago, advances across various subspecialities of...
A guide to uraemic toxicity
A guide to uraemic toxicity
When kidney function is compromised, myriad metabolites and peptides — uraemic retention molecules (URMs) — ac...
The immunology of sepsis: translating new insights into clinical practice
The immunology of sepsis: translating new insights into clinical practice
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Treatments th...
PDGFRβ CAR T cells improve fibrosis in kidney disease models
PDGFRβ CAR T cells improve fibrosis in kidney disease models
Fibrosis is a key hallmark of progressive chronic kidney disease (CKD) leading to kidney failure and is therefore an impor...
Approaches to raise awareness of CKD among patients and the general population
Approaches to raise awareness of CKD among patients and the general population
Improved awareness of chronic kidney disease (CKD) is vital to enable at-risk individuals to benefit from new therapies. I...
Born too soon: lifelong kidney risks and the importance of early intervention
Premature birth and low birth weight disrupt kidney development substantially, which leads to an increased risk of acute k...
Insights into the burden of CKDu
Chronic kidney disease of undetermined cause (CKDu) is a progressive form of chronic kidney disease (CKD) that is not asso...
Loss of B cell protection in uraemic kidney disease
Loss of B cell protection in uraemic kidney disease
The mechanisms that drive impaired immunity in people with kidney disease remain unclear. A study by Partha Biswas and col...
The kidney harbours a microbiota that may influence lithogenesis
The kidney harbours a microbiota that may influence lithogenesis
A new study provides evidence of an antibiotic-responsive kidney microbiota that may influence the formation of kidney sto...
Risk-directed management of chronic kidney disease
Risk-directed management of chronic kidney disease
The timely and rational institution of therapy is a key step towards reducing the global burden of chronic kidney disease ...
Artificial intelligence approaches to enable early detection of CKD
The late diagnosis of chronic kidney disease (CKD) is a global problem that limits the opportunity to initiate disease-mod...
Publisher Correction: Clinical practice recommendations for the diagnosis and management of X-linked hypophosphataemia
Department of Paediatric Kidney, Liver, Metabolic and Neurological Diseases, Hannover Medical, School, Hannover, GermanyDi...
Progress towards improving blood pressure control
Progress towards improving blood pressure control
Despite the availability of effective therapies, the majority of patients with hypertension have poor blood pressure contr...
Consideration of sex differences is necessary to achieve health equity
Improved understanding of the impact of sex and gender-related factors on human health and disease and the inclusion of pe...
Targeted identification of risk and treatment of diabetic kidney disease
Basic discovery and clinical trials in diabetic kidney disease (DKD) have continued to be reported in 2023 despite the dis...
Differences in the epidemiology, management and outcomes of kidney disease in men and women
Differences in the epidemiology, management and outcomes of kidney disease in men and women
Improved understanding of differences in kidney disease epidemiology, management and outcomes in men and women could help ...
Mechanisms and consequences of sex differences in immune responses
Mechanisms and consequences of sex differences in immune responses
Biological sex differences refer to differences between males and females caused by the sex chromosome complement (that is...
Author Correction: The immunoregulatory roles of non-haematopoietic cells in the kidney
Authors and AffiliationsDepartment of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USAGeorge C. Tsokos, Afr...
Renoprotective effects of sparsentan: clinical trial evidence in IgA nephropathy and FSGS
Renoprotective effects of sparsentan: clinical trial evidence in IgA nephropathy and FSGS
In early 2023, the dual endothelin–angiotensin receptor antagonist sparsentan became the first non-immunosuppressive thera...
Targeting APRIL to slow progression of IgA nephropathy
Targeting APRIL to slow progression of IgA nephropathy
Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obta...
The immunoregulatory roles of non-haematopoietic cells in the kidney
The immunoregulatory roles of non-haematopoietic cells in the kidney
The deposition of immune complexes, activation of complement and infiltration of the kidney by cells of the adaptive and i...
Kidney xenotransplantation edges closer to the clinic
Kidney xenotransplantation edges closer to the clinic
The demand for kidney transplants is far from met by human donors — a problem that may be solved by the clinical tra...
Equitable access to kidney transplants for Aboriginal and Torres Strait Islander people in Australia
Equitable access to kidney transplants for Aboriginal and Torres Strait Islander people in Australia
First Nations peoples in Australia face systemic inequities in access to kidney transplantation. The National Indigenous&a...
Transport and barrier mechanisms that regulate ciliary compartmentalization and ciliopathies
Transport and barrier mechanisms that regulate ciliary compartmentalization and ciliopathies
Primary cilia act as cell surface antennae, coordinating cellular responses to sensory inputs and signalling molecules tha...
Taking kidney temperatures to detect rejection
Taking kidney temperatures to detect rejection
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A new pathway links iron sensing with histone demethylation and regulation of mTORC1 activity
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