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Bladder cancer research is blossoming in Birmingham
Bladder cancer research is blossoming in Birmingham
The 8th Bladder Cancer Translational Research Meeting took place at the University of Birmingham, UK, in March. The sympos...
Hot flushes during ADT for prostate cancer — a clinical rationale for a neurokinin 3 receptor antagonist
Hot flushes during ADT for prostate cancer — a clinical rationale for a neurokinin 3 receptor antagonist
Hot flushes are among the most frequent and persistent adverse effects of androgen deprivation therapy for prostate cancer...
Adjuvant immunotherapy for renal cell carcinoma: understanding complexity, embracing uncertainty, making a difference
Adjuvant immunotherapy for renal cell carcinoma: understanding complexity, embracing uncertainty, making a difference
The approval of pembrolizumab as adjuvant immunotherapy for patients with clear cell renal cell carcinoma meeting the KEYN...
HER2 in urothelial cancer: clinical speed outpacing diagnostic clarity
HER2 in urothelial cancer: clinical speed outpacing diagnostic clarity
HER2-targeted antibody–drug conjugates are rapidly transforming the treatment landscape of urothelial carcinoma, wit...
Managing patients with recurrent prostate cancer who refuse ADT
Managing patients with recurrent prostate cancer who refuse ADT
Androgen deprivation therapy (ADT) is the main treatment for advanced prostate cancer, but toxic effects can affect both p...
Oligometastatic prostate cancer — bridging the gap between localized and metastatic disease
Oligometastatic prostate cancer — bridging the gap between localized and metastatic disease
The understanding of oligometastatic prostate cancer has advanced substantially in the past two decades, reshaping both di...
The future of robotic surgery in the age of artificial intelligence
The future of robotic surgery in the age of artificial intelligence
Patient outcomes after robotic surgery vary widely, often reflecting differences in surgical performance. Artificial intel...
Transitional urology: a comprehensive review of the transitional care process
Transitional urology: a comprehensive review of the transitional care process
When patients with congenital genitourinary conditions transition to adult care, they encounter multiple challenges, inclu...
Human-relevant urothelial model provides insight into infection strategies and host response
Use of a 3D urine-tolerant human urothelial model (3D-UHU), which recapitulates the crucial features of human urothelium, ...
Management and cost of stent encrustation in pregnancy
Ureteral stents are useful devices for urological management in pregnancy. However, stent encrustation occurs in up to 13%...
Clinical application of bladder MRI and the Vesical Imaging-Reporting And Data System
Diagnostic work-up and risk stratification in patients with bladder cancer before and after treatment must be refined to o...
Genetic and biological drivers of prostate cancer disparities in Black men
Genetic and biological drivers of prostate cancer disparities in Black men
Black men with prostate cancer have historically had worse outcomes than white men with prostate cancer. The causes of thi...
Generative AI in scientific publishing: disruptive or destructive?
Artificial intelligence (AI) has the potential to revolutionize scientific publishing. The influence of AI could be disrup...
Idea sprint: generating research priorities for urinary stone disease
The escalating global prevalence of urinary stone disease and its impact on public health reflects the need to synthesize ...
Prognostic and therapeutic potential of senescent stromal fibroblasts in prostate cancer
Prognostic and therapeutic potential of senescent stromal fibroblasts in prostate cancer
The stromal component of the tumour microenvironment in primary and metastatic prostate cancer can influence and promote d...
Bladder-sparing neoadjuvant therapy for MIBC
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Resolving the puzzle of same-sex sexual interactions
Sexual interactions between members of the same sex are common but the reasons for these behaviours are not always clear. ...
Hallmark discoveries in the biology of Wilms tumour
Hallmark discoveries in the biology of Wilms tumour
The modern study of Wilms tumour was prompted nearly 50 years ago, when Alfred Knudson proposed the ‘two-hit’ ...
Frequency, morbidity and equity — the case for increased research on male fertility
Frequency, morbidity and equity — the case for increased research on male fertility
Currently, most men with infertility cannot be given an aetiology, which reflects a lack of knowledge around gamete produc...
Family dynamics: fathers’ smoking affects children’s epigenetics
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Kidney xenotransplantation
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Unlocking the mystery of the human Y chromosome
Much of the Y chromosome has remained obscure owing to the challenge of sequencing repetitive genomic regions. Recently, t...
Diagnostic liquid biopsy biomarkers in renal cell cancer
Diagnostic liquid biopsy biomarkers in renal cell cancer
The clinical presentation of renal cell cancer (RCC) is shifting towards incidental and early detection, creating new chal...
Improved phenotypic classification of male infertility to promote discovery of genetic causes
Improved phenotypic classification of male infertility to promote discovery of genetic causes
An increasing number of genes are being described in the context of non-syndromic male infertility. Linking the underlying...
Feasibility and potential of an MRI-based prostate cancer screening
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Accessing information in the AI age
Online sources are increasingly being used by patients to obtain medical information. The newest of these resources, artif...
Proteomic-based analysis of testicular interstitial fluid
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A fully transperineal approach for prostate biospy
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A clinical guide to rare male sexual disorders
A clinical guide to rare male sexual disorders
Conditions referred to as ‘male sexual dysfunctions’ usually include erectile dysfunction, ejaculatory disorde...
PSMA-targeted fluorescence guidance for robotic-assisted prostatectomy
PSMA-targeted fluorescence guidance for robotic-assisted prostatectomy
Positive surgical margins are an independent risk factor for biochemical recurrence after radical prostatectomy. However, ...
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