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Are Economic Evaluations of Task Shifting Too Narrow in Focus? A Rapid Review
Are Economic Evaluations of Task Shifting Too Narrow in Focus? A Rapid Review
Task shifting between different cadres of health worker has been proposed as an approach to address workforce shortages. W...
Health Care Resource Utilization and Costs Associated with US Medicaid Sobriety Restrictions on Direct-Acting Antivirals for Hepatitis C Virus: A Retrospective Claims Database Analysis
Health Care Resource Utilization and Costs Associated with US Medicaid Sobriety Restrictions on Direct-Acting Antivirals for Hepatitis C Virus: A Retrospective Claims Database Analysis
Many state Medicaid programs implemented sobriety restrictions that delay timely initiation of direct-acting antivirals (D...
An Updated Systematic Literature Review of the Economic Costs of Loneliness and Social Isolation and the Cost Effectiveness of Interventions
An Updated Systematic Literature Review of the Economic Costs of Loneliness and Social Isolation and the Cost Effectiveness of Interventions
There has been growing interest in understanding the economic impacts of loneliness and social isolation. This study updat...
Inequalities in Quality-Adjusted Life Expectancy in Australia by Educational Attainment
Inequalities in Quality-Adjusted Life Expectancy in Australia by Educational Attainment
Summary measures such as quality-adjusted life expectancy (QALE) are increasingly used to monitor health inequalities. Soc...
Key Considerations for Assessing Real-World Comparative Effectiveness in the Context of the Drug Price Negotiation Program: A Case Study of Pembrolizumab
Key Considerations for Assessing Real-World Comparative Effectiveness in the Context of the Drug Price Negotiation Program: A Case Study of Pembrolizumab
The Centers for Medicare and Medicaid Services increasingly rely on real-world evidence to inform drug price negotiations ...
The Psychometric Performance of Generic Preference-Based Measures in Informal Carers: A Systematic Review of Validation Studies
The Psychometric Performance of Generic Preference-Based Measures in Informal Carers: A Systematic Review of Validation Studies
A growing number of health technology assessment agencies recommend inclusion of informal carer outcomes in health economi...
The Burden of Informal Caregiving for Adults with Musculoskeletal Conditions: A Systematic Review
The Burden of Informal Caregiving for Adults with Musculoskeletal Conditions: A Systematic Review
Informal caregivers play a critical role in supporting individuals with musculoskeletal conditions. This systematic review...
Integrating Environmental Impact in Health Technology Assessment: An Exploratory Study
Integrating Environmental Impact in Health Technology Assessment: An Exploratory Study
To what extent a care pathway, due to its associated pollution, may be more detrimental to future health than beneficial t...
Microsimulation Modeling for Health Decision Sciences Using C++: A Tutorial
Microsimulation Modeling for Health Decision Sciences Using C++: A Tutorial
Microsimulation models have become increasingly common in the field of decision modeling for health. Because microsimulati...
Challenges and Criteria for Single-Arm Trials Leading to an Added Benefit in German Health Technology Assessments
Challenges and Criteria for Single-Arm Trials Leading to an Added Benefit in German Health Technology Assessments
Randomized controlled trials are the standard for health technology assessment, but when they are infeasible or unethical,...
Can We Make Health Economic Decision Models as Simple as Possible, But Not Simpler? Introducing SMART tool
Can We Make Health Economic Decision Models as Simple as Possible, But Not Simpler? Introducing SMART tool
Developing health economic decision-analytic models requires making modelling choices to simplify reality while addressing...
The Cost-Effective Price of Lecanemab for Patients with Early Alzheimer’s Disease in Sweden
The Cost-Effective Price of Lecanemab for Patients with Early Alzheimer’s Disease in Sweden
We sought to estimate the cost-effective price for lecanemab for treating early Alzheimer’s disease in Sweden from t...
Evaluating the Role and Policy Implications of Using External Evidence in Survival Extrapolations: A Case Study of Axicabtagene Ciloleucel Therapy for Second-Line DLBCL
Evaluating the Role and Policy Implications of Using External Evidence in Survival Extrapolations: A Case Study of Axicabtagene Ciloleucel Therapy for Second-Line DLBCL
Health technology assessment (HTA) of haemato-oncology therapies typically requires extrapolation of long-term survival be...
Cost Effectiveness of Tremelimumab Plus Durvalumab for Unresectable Hepatocellular Carcinoma in the USA
Cost Effectiveness of Tremelimumab Plus Durvalumab for Unresectable Hepatocellular Carcinoma in the USA
Treating unresectable hepatocellular carcinoma (uHCC) is challenging. Clinical trials have shown that Single Tremelimumab ...
Unravelling the Association Between Uncertainties in Model-based Economic Analysis and Funding Recommendations of Medicines in Australia
Unravelling the Association Between Uncertainties in Model-based Economic Analysis and Funding Recommendations of Medicines in Australia
Health technology assessment is used extensively by the Pharmaceutical Benefits Advisory Committee (PBAC) to inform medici...
Economic Evaluations of Non-Pharmacological Interventions for Treating Disorders of Gut-Brain Interaction: A Scoping Review
Economic Evaluations of Non-Pharmacological Interventions for Treating Disorders of Gut-Brain Interaction: A Scoping Review
Disorders of gut-brain interaction are highly prevalent and burdensome conditions for both patients and healthcare systems...
A Multistate Model Incorporating Relative Survival Extrapolation and Mixed Time Scales for Health Technology Assessment
A Multistate Model Incorporating Relative Survival Extrapolation and Mixed Time Scales for Health Technology Assessment
Multistate models have been widely applied in health technology assessment. However, extrapolating survival in a multistat...
Public Health Impact of Introducing a Pentavalent Vaccine Against Invasive Meningococcal Disease in the United States
Public Health Impact of Introducing a Pentavalent Vaccine Against Invasive Meningococcal Disease in the United States
Invasive meningococcal disease (IMD) is primarily associated with five Neisseria meningitidis serogroups: A, B, C, W, or Y...
Cost and Cost Effectiveness of Treatments for Psoriatic Arthritis: An Updated Systematic Literature Review
Cost and Cost Effectiveness of Treatments for Psoriatic Arthritis: An Updated Systematic Literature Review
Psoriatic arthritis (PsA) is an inflammatory disease characterised by a variety of clinical manifestations. Considering th...
Different Models, Same Results: Considerations When Choosing Between Approaches to Model Cost Effectiveness of Chimeric-Antigen Receptor T-Cell Therapy Versus Standard of Care
Different Models, Same Results: Considerations When Choosing Between Approaches to Model Cost Effectiveness of Chimeric-Antigen Receptor T-Cell Therapy Versus Standard of Care
Chimeric antigen-receptor T-cell therapy (CAR-T) is characterised by early phase data at the time of registration, high up...
An Evaluation of an Algorithm for the Selection of Flexible Survival Models for Cancer Immunotherapies: Pass or Fail?
An Evaluation of an Algorithm for the Selection of Flexible Survival Models for Cancer Immunotherapies: Pass or Fail?
Accurately extrapolating survival beyond trial follow-up is essential in a health technology assessment where model choice...
Effects and Costs of Hepatitis C Virus Elimination for the Whole Population in China: A Modelling Study
Effects and Costs of Hepatitis C Virus Elimination for the Whole Population in China: A Modelling Study
China has the highest number of hepatitis C virus (HCV) infections in the world. However, it is unclear what levels of scr...
Evidence Following Conditional NICE Technology Appraisal Recommendations: A Critical Analysis of Methods, Quality and Risk of Bias
Evidence Following Conditional NICE Technology Appraisal Recommendations: A Critical Analysis of Methods, Quality and Risk of Bias
The National Institute for Health and Care Excellence (NICE) may approve health technologies on condition of more evidence...
MPES-R: Multi-Parameter Evidence Synthesis in R for Survival Extrapolation—A Tutorial
MPES-R: Multi-Parameter Evidence Synthesis in R for Survival Extrapolation—A Tutorial
Survival extrapolation often plays an important role in health technology assessment (HTA), and there are a range of diffe...
Valuation of the EORTC Quality of Life Utility Core 10 Dimensions (QLU-C10D) in a Multi-ethnic Asian Setting: How Does Having Cancer Matter?
Valuation of the EORTC Quality of Life Utility Core 10 Dimensions (QLU-C10D) in a Multi-ethnic Asian Setting: How Does Having Cancer Matter?
The aim of the study was to develop and compare utility value sets for the EORTC QLU-C10D, a cancer-specific utility instr...
Immediate Versus 5-Year Risk-Guided Initiation of Treatment for Primary Prevention of Cardiovascular Disease for Australians Aged 40 Years: A Health Economic Analysis
Immediate Versus 5-Year Risk-Guided Initiation of Treatment for Primary Prevention of Cardiovascular Disease for Australians Aged 40 Years: A Health Economic Analysis
Current Australian cardiovascular disease (CVD) prevention guidelines calculate 5-year CVD risk and recommend treatment wh...
Application of Multi-level Network Meta-Regression in the NICE Technology Appraisal of Quizartinib for Induction, Consolidation and Maintenance Treatment of Newly Diagnosed FLT3-ITD-Positive Acute Myeloid Leukaemia: An External Assessment Group Perspective
Application of Multi-level Network Meta-Regression in the NICE Technology Appraisal of Quizartinib for Induction, Consolidation and Maintenance Treatment of Newly Diagnosed FLT3-ITD-Positive Acute Myeloid Leukaemia: An External Assessment Group Perspective
NICE invited Daiichi Sankyo UK to submit evidence for the clinical and cost effectiveness of quizartinib (Vanflyta®) for t...
Cost-Effectiveness of Capivasertib as a Second-Line Therapy for Advanced Breast Cancer
Cost-Effectiveness of Capivasertib as a Second-Line Therapy for Advanced Breast Cancer
Capivasertib, a first-in-class AKT inhibitor, was recently approved as a second-line treatment for advanced breast cancer....
How Does Bereavement Affect the Health-Related Quality of Life of Household Members Who Do and Do Not Provide Unpaid Care? Difference-in-Differences Analyses Using the UK Household Longitudinal Survey
How Does Bereavement Affect the Health-Related Quality of Life of Household Members Who Do and Do Not Provide Unpaid Care? Difference-in-Differences Analyses Using the UK Household Longitudinal Survey
Guidelines for modelling in economic evaluation recommend that it may be necessary to consider costs and outcomes until al...
Value of Innovative Multiple Myeloma Treatments from Patient and Healthcare Provider Perspectives: Evidence from a Discrete Choice Experiment
Value of Innovative Multiple Myeloma Treatments from Patient and Healthcare Provider Perspectives: Evidence from a Discrete Choice Experiment
Although innovation generally provides measurable improvements in disease characteristics and patient survival, some benef...
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