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Tumor-activated Theranostic Probe To Enhance Photodynamic Eradication of Solid Tumors by a Three-Pronged Strategy
Tumor-activated Theranostic Probe To Enhance Photodynamic Eradication of Solid Tumors by a Three-Pronged Strategy
Photodynamic therapy (PDT) has been widely deployed in clinical tumor treatment due to its light controllability and minim...
Solvent Polarity Matching for the Fabrication of Evenly Distributed Metal-Organic Framework Stationary Phases
Solvent Polarity Matching for the Fabrication of Evenly Distributed Metal-Organic Framework Stationary Phases
Stationary phase optimization is crucial for enhancing gas chromatography (GC) separation performance, yet coating process...
Cantilever-Enhanced Fiber-Optic Photoacoustic Micro-Water and Pressure Sensor for SF Insulation Equipment Monitoring
Cantilever-Enhanced Fiber-Optic Photoacoustic Micro-Water and Pressure Sensor for SF Insulation Equipment Monitoring
A miniature cantilever-enhanced fiber-optic photoacoustic sensor (FOPAS) is designed for micro-water and pressure measurem...
An Integrated Microfluidic Platform Possessing Uniform Tumor Spheroids for Evaluating Radio-Therapeutic Nanomaterials
An Integrated Microfluidic Platform Possessing Uniform Tumor Spheroids for Evaluating Radio-Therapeutic Nanomaterials
Abundant new nanomaterials are developed every year to enhance traditional radiotherapy by improving therapeutic response ...
Genetically Encoded Alkyne-Based Cross-linkable Probes
Genetically Encoded Alkyne-Based Cross-linkable Probes
The non-covalent interactions of ubiquitin/ubiquitin-like proteins (Ub/Ubls) with other proteins play a pivotal role in re...
Multiplex MicroRNA Profiling Using a Logic Nanodevice-Based Electrochemiluminescence Biosensor for the Rapid Diagnosis of Acute Myocardial Infarction
Multiplex MicroRNA Profiling Using a Logic Nanodevice-Based Electrochemiluminescence Biosensor for the Rapid Diagnosis of Acute Myocardial Infarction
Developing reliable biological computing circuit devices for microRNA (miRNA) assays is critical in facilitating the early...
One-Step In-Situ Synthesis of Porous AuRu Solid-Solution Alloy for Efficient Non-Enzymatic Glucose Sensing Application
One-Step In-Situ Synthesis of Porous AuRu Solid-Solution Alloy for Efficient Non-Enzymatic Glucose Sensing Application
The practicality of the non-enzymatic glucose sensing depends on the development of cost-effective, binder-free, and highl...
Density-Based Resampling Strategy Unveils Metabolic Heterogeneity and Subtypes in Liver Disease Progression
Density-Based Resampling Strategy Unveils Metabolic Heterogeneity and Subtypes in Liver Disease Progression
Metabolomics studies of heterogeneous diseases, such as hepatitis B virus (HBV) infection, liver cirrhosis (LC), and hepat...
Mass Spectrometry-Based Multi-Omics Integration Decodes Metabolic-Immune Crosstalk in Multifocal Breast Cancer Progression
Mass Spectrometry-Based Multi-Omics Integration Decodes Metabolic-Immune Crosstalk in Multifocal Breast Cancer Progression
The heterogeneity in the different primary tumor sites of metabolic-immune networks across multifocal tumors remains a cri...
Cell-Permeable Mitochondrial-Targeting Probes Enable Precise Tracking Via the Interplay between Electrostatic Interaction and Lipid-Tail Anchoring Mechanism
Cell-Permeable Mitochondrial-Targeting Probes Enable Precise Tracking Via the Interplay between Electrostatic Interaction and Lipid-Tail Anchoring Mechanism
Mitochondria constitute vital organelles in eukaryotic cells, essential not only for adenosine triphosphate (ATP) synthesi...
Decoding Soft Metals Multifunctional Fluorescent Probes for Selective Ag and Hg Sensing
Decoding Soft Metals Multifunctional Fluorescent Probes for Selective Ag and Hg Sensing
Ag+ and Hg2+ are soft, thiophilic cations of high environmental and biomedical relevance, yet their closely related coordi...
Portable Microfluidic Detection of via MOF-CRISPR–Cas12a Cascade Signal Amplification
Portable Microfluidic Detection of via MOF-CRISPR–Cas12a Cascade Signal Amplification
Mycoplasma pneumoniae (MP) is a major pathogen of community-acquired pneumonia, especially in children, but its early diag...
Real-Time Imaging of Pulmonary Inflammation and Smoke-Induced Lung Toxicity via a Near-Infrared Probe Targeting Butyrylcholinesterase Activity
Real-Time Imaging of Pulmonary Inflammation and Smoke-Induced Lung Toxicity via a Near-Infrared Probe Targeting Butyrylcholinesterase Activity
Monitoring pulmonary injury caused by environmental exposures remains a critical challenge in toxicological and diagnostic...
Comparative Evaluation of Three Serum Thawing Methods and Their Effects on Metabolome Integrity and Biomarker Discovery
Comparative Evaluation of Three Serum Thawing Methods and Their Effects on Metabolome Integrity and Biomarker Discovery
Serum samples are widely used in metabolomics studies and are typically stored at −80 °C after collect...
From Sensing to Prediction: A Machine Learning-Enhanced Electrochemical Platform for Ultrasensitive Monitoring of Bioactive Flavonoids
From Sensing to Prediction: A Machine Learning-Enhanced Electrochemical Platform for Ultrasensitive Monitoring of Bioactive Flavonoids
Rutin (Rt) and quercetin (Qt), two prominent bioactive flavonoids, are widely present in functional foods and beverages, o...
Highly Sensitive Analysis of Iodine in Seawater via Headspace Solid-Phase Microextraction Coupled with Gas Chromatography-Mass Spectrometry
Highly Sensitive Analysis of Iodine in Seawater via Headspace Solid-Phase Microextraction Coupled with Gas Chromatography-Mass Spectrometry
Monitoring iodine speciation in marine environments holds immense significance due to its profound implications for human ...
A Microcontroller-Integrated Multichannel Time Detector for Paper-Based Analytical Devices — Applications to Viscosity Measurements in Saliva Analysis and Protease-Activity Assays
A Microcontroller-Integrated Multichannel Time Detector for Paper-Based Analytical Devices — Applications to Viscosity Measurements in Saliva Analysis and Protease-Activity Assays
We designed and developed a microcontroller-integrated multichannel time detection system that uses a microfluidic paper-b...
Multiple miRNA Analysis Based on DNA Fiber Barcodes for Cell Typing
Multiple miRNA Analysis Based on DNA Fiber Barcodes for Cell Typing
Tumor cell subtyping is clinically critical for early cancer diagnosis and prognostic assessment. As key regulators of cel...
Peltier-Based Temperature Control Enables High-Bandwidth and Low-Noise Measurements with Solid-State Nanopores
Peltier-Based Temperature Control Enables High-Bandwidth and Low-Noise Measurements with Solid-State Nanopores
Temperature is a fundamental yet underexploited control parameter in nanopore-based single-molecule sensing, critically in...
Tailored Assembly of Electronically Engineered Gold Nanoclusters for On-Chip Visual Detection of Nitrogen-Rich Heterocyclic Explosives
Tailored Assembly of Electronically Engineered Gold Nanoclusters for On-Chip Visual Detection of Nitrogen-Rich Heterocyclic Explosives
Rapid and reliable detection of emerging nitrogen-rich heterocyclic explosives is essential for security and environmental...
Optical Detection and Recovery of Palladium Ions in Aqueous Solutions Using Organic Sensor-Modified Mesoporous Silica Nano-spheres
Optical Detection and Recovery of Palladium Ions in Aqueous Solutions Using Organic Sensor-Modified Mesoporous Silica Nano-spheres
Here, we introduce a new pH-responsive optical nanosensor designed for precise detection and selective uptake of Pd2+ ions...
Dual-Signal Homogeneous Electrochemical System for Turn-On Assay of MicroRNA Based on Target-Switched Cyclic Amplification
Dual-Signal Homogeneous Electrochemical System for Turn-On Assay of MicroRNA Based on Target-Switched Cyclic Amplification
Dual-signal electrochemical sensors have inherent self-correction function to overcome disturbances of experimental and en...
Point-of-Care Testing for Abnormal Amino Acid Metabolism: Visualized Colorimetric Detection of Tryptophan Based on Au@MnO Nanoparticles
Point-of-Care Testing for Abnormal Amino Acid Metabolism: Visualized Colorimetric Detection of Tryptophan Based on Au@MnO Nanoparticles
In this study, a novel colorimetric detection method for tryptophan is developed using Au@MnO2 NPs based on their redox re...
Molecularly Imprinted Ratiometric Fluorescence Sensors for Screening and Identification of New Pollutants
Molecularly Imprinted Ratiometric Fluorescence Sensors for Screening and Identification of New Pollutants
New pollutants (NPs) are characterized by their concealment, persistence, and bioaccumulation and have emerged as a major ...
Aggregation-Induced Emission Probe for Ratiometric Fluorescence Detection of Sodium Tetraborate on Meat Surfaces
Aggregation-Induced Emission Probe for Ratiometric Fluorescence Detection of Sodium Tetraborate on Meat Surfaces
The detection of sodium tetraborate (ST) in meat is crucial for protecting human health. Surface analysis is a rapid onsit...
A New Disposable Paper-Based Chemosensor for the Rapid and Direct Detection of Hexavalent Chromium in Aqueous Media
A New Disposable Paper-Based Chemosensor for the Rapid and Direct Detection of Hexavalent Chromium in Aqueous Media
Hexavalent chromium (Cr6+) poses significant risks to both individuals and the environment. However, direct detection of C...
Natural Deep Eutectic Solvents as a Green Alternative for Extracting Contaminants from Food Samples: A Review
Natural Deep Eutectic Solvents as a Green Alternative for Extracting Contaminants from Food Samples: A Review
Green Analytical Chemistry attempts to develop analytical procedures that reduce the environmental impact of the reagents ...
NIR Hyperspectral Imaging Combined with Chemometrics for Mapping Water Patterns During Dehydration of Nonvascular Epiphytic Communities
NIR Hyperspectral Imaging Combined with Chemometrics for Mapping Water Patterns During Dehydration of Nonvascular Epiphytic Communities
In recent years, nonvascular epiphytic communities have been increasingly subjected to extreme climatic conditions, with h...
Construction of an “aptamer-target-peptide” Sandwich Electrochemical Biosensor for Ultrasensitive Assay of Amyloid-Beta Oligomers based on Bimetallic Covalent Organic Framework
Construction of an “aptamer-target-peptide” Sandwich Electrochemical Biosensor for Ultrasensitive Assay of Amyloid-Beta Oligomers based on Bimetallic Covalent Organic Framework
In view of the importance of quantification of beta-amyloid (Aβ), an “aptamer -target- peptide” sandwich ...
Enhanced Photoelectrochemical Performance of CoOOH/ZnCdS-Vs Co-Catalyst and Defect Engineering for Detection of Cu and D-penicillamine
Enhanced Photoelectrochemical Performance of CoOOH/ZnCdS-Vs Co-Catalyst and Defect Engineering for Detection of Cu and D-penicillamine
In this work, a CoOOH/ZnCdS-Vs sensor with high photoelectrochemical (PEC) performance was successfully developed through ...
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