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Author Correction: Cytoskeleton-functionalized synthetic cells with life-like mechanical features and regulated membrane dynamicity
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 ...
Publisher Correction: Protocells by spontaneous reaction of cysteine with short-chain thioesters
Publisher Correction: Protocells by spontaneous reaction of cysteine with short-chain thioesters
Author notesYei-Chen LaiPresent address: Department of Chemistry, National Chung Hsing University, Taichung City, TaiwanTh...
Mesoporous single-crystal metal–organic frameworks
Mesoporous single-crystal metal–organic frameworks
The structural diversity of mesoporous metal–organic frameworks (MOFs) is limited, and known examples are typically ...
Coacervating proteins stick like a tick
Coacervating proteins stick like a tick
Ticks secrete a protein-based saliva that hardens into a cement, ensuring that they firmly attach to their host. Now, insi...
Computational design of highly signalling-active membrane receptors through solvent-mediated allosteric networks
Computational design of highly signalling-active membrane receptors through solvent-mediated allosteric networks
Protein catalysis and allostery require the atomic-level orchestration and motion of residues and ligand, solvent and prot...
A living library concept to capture the dynamics and reactivity of mixed-metal clusters for catalysis
A living library concept to capture the dynamics and reactivity of mixed-metal clusters for catalysis
The exploration of ligated metal clusters’ chemical space is challenging, partly owing to an insufficiently targeted...
Supramolecular dyads as photogenerated qubit candidates
Supramolecular dyads as photogenerated qubit candidates
Molecular spin qubits have the advantages of synthetic flexibility and amenability to be tailored to specific applications...
Enantioselective synthesis of 2-substituted bicyclo[1.1.1]pentanes via sequential asymmetric imine addition of bicyclo[1.1.0]butanes and skeletal editing
Enantioselective synthesis of 2-substituted bicyclo[1.1.1]pentanes via sequential asymmetric imine addition of bicyclo[1.1.0]butanes and skeletal editing
The substitution of an aromatic ring with a C(sp3)-rich bicyclic hydrocarbon, known as bioisosteric replacement, plays a c...
Electrochemical labelling of hydroxyindoles with chemoselectivity for site-specific protein bioconjugation
Electrochemical labelling of hydroxyindoles with chemoselectivity for site-specific protein bioconjugation
Electrochemistry has recently emerged as a powerful approach in small-molecule synthesis owing to its numerous attractive ...
Modular α-tertiary amino ester synthesis through cobalt-catalysed asymmetric aza-Barbier reaction
Modular α-tertiary amino ester synthesis through cobalt-catalysed asymmetric aza-Barbier reaction
Unnatural chiral α-tertiary amino acids containing two different carbon-based substituents at the α-carbon centr...
Organocatalytic aromatization-promoted umpolung reaction of imines
Organocatalytic aromatization-promoted umpolung reaction of imines
The umpolung functionalization of imines bears vast synthetic potential, but polarity inversion is less efficient compared...
Artificial cell synthesis using biocatalytic polymerization-induced self-assembly
Artificial cell synthesis using biocatalytic polymerization-induced self-assembly
Artificial cells are biomimetic microstructures that mimic functions of natural cells, can be applied as building blocks f...
Subdomain dynamics enable chemical chain reactions in non-ribosomal peptide synthetases
Subdomain dynamics enable chemical chain reactions in non-ribosomal peptide synthetases
Many peptide-derived natural products are produced by non-ribosomal peptide synthetases (NRPSs) in an assembly-line fashio...
Air- and photo-stable luminescent carbodicarbene-azaboraacenium ions
Air- and photo-stable luminescent carbodicarbene-azaboraacenium ions
Substitution of a C=C bond by an isoelectronic B–N bond is a well-established strategy to alter the electronic struc...
Azobenzene as a photoswitchable mechanophore
Azobenzene as a photoswitchable mechanophore
Azobenzene has been widely explored as a photoresponsive element in materials science. Although some studies have investig...
Cooperative H2 activation at a nickel(0)–olefin centre
Cooperative H2 activation at a nickel(0)–olefin centre
Catalytic olefin hydrogenation is ubiquitous in organic synthesis. In most proposed homogeneous catalytic cycles, reactive...
A general copper-catalysed enantioconvergent C(sp3)–S cross-coupling via biomimetic radical homolytic substitution
A general copper-catalysed enantioconvergent C(sp3)–S cross-coupling via biomimetic radical homolytic substitution
Although α-chiral C(sp3)–S bonds are of enormous importance in organic synthesis and related areas, the transit...
The year dot
The year dot
Quantum dots are nanometre-sized semiconducting crystals. While chemists tend to interrogate molecular structure to unders...
From feedstock to pharmaceuticals
From feedstock to pharmaceuticals
Fluoroalkyl fragments are ubiquitous motifs in pharmaceuticals and agrochemicals, but their introduction to a given molecu...
An acid for an acid
An acid for an acid
Stereoselective decarboxylative protonation can produce diverse chiral molecules from widely available carboxylic acids. H...
The joys and challenges of teaching for the first time
The joys and challenges of teaching for the first time
Becoming an assistant professor brings with it numerous challenges, one of which is teaching undergraduate courses for the...
Insulin investigations
Insulin investigations
Daniel Rabinovich outlines the story of insulin, the essential drug for the treatment of diabetes during the past century.
Lateral epitaxial growth of two-dimensional organic heterostructures
Lateral epitaxial growth of two-dimensional organic heterostructures
Two-dimensional organic lateral heterostructures (2D OLHs) are attractive for the fabrication of functional materials. How...
Using symmetry to drive new protein assemblies
Using symmetry to drive new protein assemblies
Recent improvements in de novo protein design are likely to support a broad range of applications, but larger complexes wi...
Author Correction: Circumventing the stability problems of graphene nanoribbon zigzag edges
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
Publisher Correction: Photocatalytic hydrofluoroalkylation of alkenes with carboxylic acids
Author notesThese authors contributed equally: Kang-Jie Bian, Yen-Chu Lu.Authors and AffiliationsDepartment of Chemistry, ...
Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learning
Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learning
Late-stage functionalization is an economical approach to optimize the properties of drug candidates. However, the chemica...
A general strategy to develop fluorogenic polymethine dyes for bioimaging
A general strategy to develop fluorogenic polymethine dyes for bioimaging
Fluorescence imaging is an invaluable tool to study biological processes and further progress depends on the development o...
Publisher Correction: Droplet slipperiness despite surface heterogeneity at molecular scale
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
Phase-separation behaviour of RNAs
Phase-separation behaviour of RNAs
Ribonucleoprotein granules are ubiquitous in living organisms with the protein and RNA components having distinct roles. I...
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