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Exploring a specialized lactylation pattern to predict the prognosis and sensitivity of immunotherapy in breast cancer via machine learning
Exploring a specialized lactylation pattern to predict the prognosis and sensitivity of immunotherapy in breast cancer via machine learning
With the global incidence of breast cancer steadily increasing, there is a critical need to explore novel molecular mechan...
Venlafaxine reduces hot flashes in hormone receptor-positive breast cancer patients receiving tamoxifen: a prospective single-arm, open-label trial
Venlafaxine reduces hot flashes in hormone receptor-positive breast cancer patients receiving tamoxifen: a prospective single-arm, open-label trial
Although venlafaxine has shown efficacy for hot flashes in hormone receptor–positive breast cancer, evidence in Asia...
tRNA modification genes are associated with genomic instability, proliferative programs, and poor prognosis in breast cancer
tRNA modification genes are associated with genomic instability, proliferative programs, and poor prognosis in breast cancer
The modifications of transfer RNA (tRNA) add an extra layer of post-transcriptional gene regulation in cancer biology. Whi...
An investigation to identify the factors for negative sentinel lymph node metastasis in early breast cancer cases
An investigation to identify the factors for negative sentinel lymph node metastasis in early breast cancer cases
Sentinel Lymph Node Biopsy (SLNB) in breast cancer (BC) is a standard procedure. Omission of SLNB in BC is an evolving are...
Presenteeism in working-age breast cancer survivors 1–5 years after surgery: relative contributions of treatment-related symptoms and modifiable factors
Presenteeism in working-age breast cancer survivors 1–5 years after surgery: relative contributions of treatment-related symptoms and modifiable factors
Presenteeism among working-age breast cancer survivors drives job loss and economic burden, but the extent to which it is ...
Real-world outcomes of palbociclib plus endocrine therapy in elderly patients with HR+/HER2- advanced breast cancer in Japan: a subgroup analysis of the P-BRIDGE study by age group
Real-world outcomes of palbociclib plus endocrine therapy in elderly patients with HR+/HER2- advanced breast cancer in Japan: a subgroup analysis of the P-BRIDGE study by age group
Palbociclib (PAL), a cyclin-dependent kinase 4/6 inhibitor, plus endocrine therapy (ET) is recommended as first-line (1L) ...
FGFR4 and HER2 co-expression is associated with the proinflammatory tumor microenvironment in HR + breast cancer
FGFR4 and HER2 co-expression is associated with the proinflammatory tumor microenvironment in HR + breast cancer
Dysregulated FGFR4 signaling has been associated with aggressive subtypes of breast cancers, characterized by HER2 enrichm...
Cost-effectiveness analysis of the Oncotype DX Breast Recurrence Score test among node-negative early breast cancer patients in Japan
Cost-effectiveness analysis of the Oncotype DX Breast Recurrence Score test among node-negative early breast cancer patients in Japan
The Oncotype DX Breast Recurrence Score® test is prognostic for distant recurrence in hormone receptor positive (HR+)...
Prognostic model for pulmonary metastasis in patients with HER2-positive breast cancer: a population-based study
Prognostic model for pulmonary metastasis in patients with HER2-positive breast cancer: a population-based study
Lung metastasis is an important adverse prognostic factor in patients with HER2-positive breast cancer. However, a lack of...
Prognostic significance of peripheral myeloid-derived suppressor cells in advanced breast cancer
Prognostic significance of peripheral myeloid-derived suppressor cells in advanced breast cancer
The exact roles of myeloid-derived suppressor cells (MDSCs) and regulatory T cells in the peripheral blood of individuals ...
mutation in ER-negative and HER2-positive breast cancer with apocrine differentiation
mutation in ER-negative and HER2-positive breast cancer with apocrine differentiation
Targeted therapies for PIK3CA-mutated breast cancer are currently limited to the hormone receptor (HR)-positive and HER2-n...
Efficacy of xeno-free induced mesenchymal stem/stromal cells in enhancing autologous fat graft survival
Efficacy of xeno-free induced mesenchymal stem/stromal cells in enhancing autologous fat graft survival
Breast reconstruction using autologous fat grafting offers a less invasive alternative with shorter surgical times compare...
Three cases of whole breast irradiation for breast cancer in patients with Lymphangioleiomyomatosis (LAM)
Three cases of whole breast irradiation for breast cancer in patients with Lymphangioleiomyomatosis (LAM)
Lymphangioleiomyomatosis (LAM) is a rare, low-grade metastatic disease characterized by cystic lung destruction. The exist...
UGT2B17 as a predictive biomarker of complete pathological response in HER2 + breast cancer
UGT2B17 as a predictive biomarker of complete pathological response in HER2 + breast cancer
Pathological complete response (pCR) after neoadjuvant therapy is a robust surrogate marker for long-term outcomes in brea...
Impact of sentinel lymph node biopsy versus axillary lymph node dissection on shoulder range of motion in early rehabilitation after breast cancer surgery
Impact of sentinel lymph node biopsy versus axillary lymph node dissection on shoulder range of motion in early rehabilitation after breast cancer surgery
The impact of early rehabilitation on shoulder range of motion (ROM) limitation following sentinel lymph node biopsy (SLNB...
Time-dependent diffusion MRI for non-invasive differentiation of benign and malignant breast lesions and evaluation of proliferation index biomarkers
Time-dependent diffusion MRI for non-invasive differentiation of benign and malignant breast lesions and evaluation of proliferation index biomarkers
To establish a dual-task assessment framework using time-dependent diffusion MRI (td-dMRI) for: (1) differentiating benign...
Expression of HER2, HER3, and TROP2 in primary tumors and brain metastases of breast cancer
Expression of HER2, HER3, and TROP2 in primary tumors and brain metastases of breast cancer
Human epidermal growth factor receptor 2 (HER2)-directed antibody–drug conjugate (ADC) therapy has shown efficacy in...
Early outcomes of accelerated partial breast irradiation and dosimetric comparison of volumetric modulated arc therapy and three-dimensional conformal radiotherapy
Early outcomes of accelerated partial breast irradiation and dosimetric comparison of volumetric modulated arc therapy and three-dimensional conformal radiotherapy
Guidelines for partial breast irradiation as postoperative radiotherapy following breast-conserving therapy for breast can...
Two-hit events occurred independently in bilateral breast cancers in a germline double heterozygous carrier for and
Two-hit events occurred independently in bilateral breast cancers in a germline double heterozygous carrier for and
While patients with hereditary breast and ovarian cancer with germline double heterozygosity (GDH) for BRCA1 and BRCA2 are...
Development of a deep learning-based automated diagnostic system (DLADS) for classifying mammographic lesions — a first large-scale multi-institutional clinical trial in Japan
Development of a deep learning-based automated diagnostic system (DLADS) for classifying mammographic lesions — a first large-scale multi-institutional clinical trial in Japan
Recently, western countries have built evidence on mammographic artificial Intelligence—computer-aided diagnosis (AI...
Major anatomic variations of the lateral upper arm lymphatic pathway in a healthy female population
Major anatomic variations of the lateral upper arm lymphatic pathway in a healthy female population
The lateral upper arm (LUA) pathway is a route of superficial lymphatic drainage that bypasses the axilla by draining to t...
Health-related quality of life and physical activity collected via mobile application and wearable device in patients with HR +/HER2 − advanced breast cancer treated with palbociclib plus endocrine therapy or endocrine therapy alone: 6-month longitudinal study (JBCRG-26)
Health-related quality of life and physical activity collected via mobile application and wearable device in patients with HR +/HER2 − advanced breast cancer treated with palbociclib plus endocrine therapy or endocrine therapy alone: 6-month longitudinal study (JBCRG-26)
To summarize descriptively health-related quality of life (HRQOL) and physical activity (PA) evaluated with a mobile appli...
Breast tumors with intermediate ER expression differ biologically from ER-low tumors and exhibit a more favorable prognosis
Breast tumors with intermediate ER expression differ biologically from ER-low tumors and exhibit a more favorable prognosis
Estrogen receptor (ER) expression in breast cancer exhibits a widely recognized bimodal distribution, with increasing focu...
Mapping the clinical topography and progression of venous thromboembolism in Chinese breast cancer surgical patients: a prospective longitudinal study
Mapping the clinical topography and progression of venous thromboembolism in Chinese breast cancer surgical patients: a prospective longitudinal study
Venous thromboembolism (VTE) is a serious complication in breast cancer patients. However, limited attention has been give...
Baseline risk variability by eligibility criteria in Cohort 1 of the monarchE trial for high-risk HR-positive, HER2-negative breast cancer
Baseline risk variability by eligibility criteria in Cohort 1 of the monarchE trial for high-risk HR-positive, HER2-negative breast cancer
Baseline recurrence risk increasingly guides adjuvant endocrine therapy for hormone receptor (HR)-positive, human epiderma...
Internal mammary node failure in invasive breast cancer patients who received post-operative radiotherapy without prophylactic internal mammary node irradiation
Internal mammary node failure in invasive breast cancer patients who received post-operative radiotherapy without prophylactic internal mammary node irradiation
Breast cancer (BC) patients who would benefit the most from prophylactic internal mammary node (IMN) irradiation have not ...
A retrospective multi-center cohort study investigating safety of sentinel lymph node biopsy for axillary staging in clinical T3-4c breast cancer
A retrospective multi-center cohort study investigating safety of sentinel lymph node biopsy for axillary staging in clinical T3-4c breast cancer
Sentinel lymph node biopsy (SLNB) has become a standard procedure for patients with breast cancer (BC) without clinically ...
Impact of modified dexamethasone administration sequence on infusion reaction incidence in HER2-positive breast cancer: a randomized multicenter trial
Impact of modified dexamethasone administration sequence on infusion reaction incidence in HER2-positive breast cancer: a randomized multicenter trial
Infusion reactions (IRs) are common adverse events associated with HER2-targeted monoclonal antibodies, such as trastuzuma...
Regional disparities in breast cancer healthcare in Japan: REAL-BC study
Regional disparities in breast cancer healthcare in Japan: REAL-BC study
Since 2007, the Basic Plans for Promoting Cancer Control (BPPCCs) have sought to enhance cancer care at designated cancer ...
A systematic review of the efficacy of cancer vaccines in advanced breast cancer
A systematic review of the efficacy of cancer vaccines in advanced breast cancer
Cancer vaccines offer an innovative approach to treating advanced breast cancer, by activating the immune system to recogn...
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