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Proposed Role of RGS1 in Modulating IL-1β-IL-1R1-IRAK4-TAK1 Signaling in Endometriotic Stromal Cells
Proposed Role of RGS1 in Modulating IL-1β-IL-1R1-IRAK4-TAK1 Signaling in Endometriotic Stromal Cells
The pathology of endometriosis is associated with various inflammatory cytokines, including IL-1β, and recent studies...
Polycystic Ovary Syndrome (PCOS): A Comprehensive Review of Clinical Approaches, Functional Bioactives, and Nutritional Interventions
Polycystic Ovary Syndrome (PCOS): A Comprehensive Review of Clinical Approaches, Functional Bioactives, and Nutritional Interventions
Polycystic Ovary Syndrome (PCOS) is a complex endocrine condition that profoundly affects the reproductive, metabolic, and...
Significant Implications OfR-126 Expression With Respect to Its Target Gene in the Pathogenesis of Recurrent Pregnancy Losses (RPL)-a Study in High Incidence Zone
Significant Implications OfR-126 Expression With Respect to Its Target Gene in the Pathogenesis of Recurrent Pregnancy Losses (RPL)-a Study in High Incidence Zone
Owing to crucial role played by MicroRNA-126 (miR-126) in vascular development and regulation of vascular endothelial grow...
Correction: Chronic Stress Destabilizes Ectoplasmic Specialization Dynamics in the Rat Testis via Downregulating the Focal Adhesion Kinase-Associated Protein Complex
Correction: Chronic Stress Destabilizes Ectoplasmic Specialization Dynamics in the Rat Testis via Downregulating the Focal Adhesion Kinase-Associated Protein Complex
Correction: Reproductive SciencesThe original online version of this article was revi...
Tissue Specific Necroptosis in the Cervix, Uterus, and Placenta in an LPS-induced Preterm Birth Model
Tissue Specific Necroptosis in the Cervix, Uterus, and Placenta in an LPS-induced Preterm Birth Model
Preterm birth remains a preventable cause of death for both mothers and infants. However, due to its association with nume...
The Impact of Conventional Chemotherapy Regimens and Targeted Drugs on Ovarian Function in Breast Cancer Patients
The Impact of Conventional Chemotherapy Regimens and Targeted Drugs on Ovarian Function in Breast Cancer Patients
Breast cancer is the most common malignancy among women, affecting nearly 1.5 million individuals worldwide every...
Melatonin in Preeclampsia: a Systematic Review of its Role in Pathogenesis and Therapeutic Potential
Melatonin in Preeclampsia: a Systematic Review of its Role in Pathogenesis and Therapeutic Potential
Preeclampsia (PE) is a hypertensive disorder of pregnancy that contributes substantially to maternal and fetal morbidity a...
Lactoferrin as a Non-Hormonal Therapeutic Candidate for Endometriosis: Mechanisms and Future Directions
Lactoferrin as a Non-Hormonal Therapeutic Candidate for Endometriosis: Mechanisms and Future Directions
The pathogenesis and progression of endometriosis may involve a complex combination of multiple factors, including chronic...
Integrative Analysis of Alternative Splicing Regulation Reveals Genetic and RBP-Mediated Mechanisms in Endometriosis Pathogenesis
Integrative Analysis of Alternative Splicing Regulation Reveals Genetic and RBP-Mediated Mechanisms in Endometriosis Pathogenesis
Alternative splicing (AS) plays a crucial role in various diseases, yet its functional significance in endometriosis remai...
Therapeutic Potential of Bone Marrow- and Ovarian/Endometrium-Derived Mesenchymal Stem Cells in Regulating Ovarian Function in a Streptozotocin-Induced Diabetes Mellitus Rat Model
Therapeutic Potential of Bone Marrow- and Ovarian/Endometrium-Derived Mesenchymal Stem Cells in Regulating Ovarian Function in a Streptozotocin-Induced Diabetes Mellitus Rat Model
Streptozotocin (STZ)-induced pancreatic damage leads to β-cell injury and hyperglycemia, providing a controlled model...
Normal Fertility of (exon2 KO)/(exon2 c.106T > C Mut) Compound Heterozygous Mutant Male Mice
Normal Fertility of (exon2 KO)/(exon2 c.106T > C Mut) Compound Heterozygous Mutant Male Mice
Asthenozoospermia is a common factor in male infertility, and male infertility associated with primary ciliary dyskinesia ...
Early Placental Angioactive Response to Maternal SARS-CoV-2 Infection: an Immunohistochemical Study
Early Placental Angioactive Response to Maternal SARS-CoV-2 Infection: an Immunohistochemical Study
SARS-CoV-2, responsible for COVID-19, affects multiple bodily systems, including placenta. Understanding its effects on pl...
Molecular Characteristics of the Endometrium in Polycystic Ovary Syndrome with Insulin Resistance
Molecular Characteristics of the Endometrium in Polycystic Ovary Syndrome with Insulin Resistance
Polycystic ovary syndrome (PCOS), one of the most common endocrine and reproductive disorders in women of reproductive age...
Downregulation of DACH2 Expression in an Adrenocortical Cell Model of PCOS with Adrenal Hyperandrogenism, and in Human Granulosa Cells from Patients with Hyperandrogenic-PCOS: a Link Between Ovaries and Adrenal Glands in PCOS
Downregulation of DACH2 Expression in an Adrenocortical Cell Model of PCOS with Adrenal Hyperandrogenism, and in Human Granulosa Cells from Patients with Hyperandrogenic-PCOS: a Link Between Ovaries and Adrenal Glands in PCOS
Ahmed KEM, Frøysa HG, Karlsen OA, Sagen JV, Mellgren G, Verhaegen S, et al. LC-MS/MS based profiling and dynamic modelling...
Autophagy and Lysosomal Dysregulation in Endometriosis: Therapeutic Opportunities and Molecular Insights
Autophagy and Lysosomal Dysregulation in Endometriosis: Therapeutic Opportunities and Molecular Insights
Endometriosis is a chronic estrogen-dependent inflammatory condition caused by the presence of endometrium-like tissue out...
Comprehensive Analysis of the Predictive Value of Adenylate Cyclase 4 on Clinical Significance, Prognosis, and Immunotherapy in Human Cancers
Comprehensive Analysis of the Predictive Value of Adenylate Cyclase 4 on Clinical Significance, Prognosis, and Immunotherapy in Human Cancers
Adenylate cyclase 4 (ADCY4), a member of the adenylate cyclase family, is an enzyme responsible for catalyzing the synthes...
Aging-Induced Downregulation of DNA Polymerase β Impairing Base Excision Repair Causes Testicular Dysfunction
Aging-Induced Downregulation of DNA Polymerase β Impairing Base Excision Repair Causes Testicular Dysfunction
Base excision repair (BER) is essential for maintaining genomic stability, with DNA polymerase β (Pol β) serving...
Transhymenal Vaginoscopic Resection of a Large Polypoid Cervical Endometriosis in an Adolescent Girl: Case Report and Literature Review
Transhymenal Vaginoscopic Resection of a Large Polypoid Cervical Endometriosis in an Adolescent Girl: Case Report and Literature Review
Cervical endometriosis is an uncommon site and a distinctive entity of this enigmatic disease. It has a different clinical...
Utilization of MSC-Derived Extracellular Vesicles and Bioscaffolds in Enhancing Oocyte In Vitro Maturation and Culture: A Review
Utilization of MSC-Derived Extracellular Vesicles and Bioscaffolds in Enhancing Oocyte In Vitro Maturation and Culture: A Review
Failure in germ cells development and oocyte maturation remains a significant challenge in assisted reproductive technolog...
Preeclampsia is Associated with Altered Expression of Ferroptosis Biomarkers in Placental but not Maternal Vasculature
Preeclampsia is Associated with Altered Expression of Ferroptosis Biomarkers in Placental but not Maternal Vasculature
Ferroptosis, an iron-dependent mechanism of programmed cell death, has been implicated in the pathogenesis of preeclampsia...
The Functional Role of Cumulus Cells and Their Influence on Oocyte Quality: A Systematic Review
The Functional Role of Cumulus Cells and Their Influence on Oocyte Quality: A Systematic Review
A systematic review was conducted pertaining to the biologic processes of cumulus cells and measures of oocyte quality. Th...
Endometrial Mesenchymal Stem Cell-Derived Exosomal miR-4669 Promotes EMT in Adenomyosis by Inducing M2 Macrophage Polarization via the DUSP6/ERK Pathway
Endometrial Mesenchymal Stem Cell-Derived Exosomal miR-4669 Promotes EMT in Adenomyosis by Inducing M2 Macrophage Polarization via the DUSP6/ERK Pathway
Adenomyosis (AM), a gynecological disorder that severely affects female reproductive health. AM-associated macrophage (AAM...
The Effect of Music and Mandala Activity on Stress and Stress-Coping Levels of Infertile Women Who Had an Embryo Transfer: A Randomized Clinical Trial
The Effect of Music and Mandala Activity on Stress and Stress-Coping Levels of Infertile Women Who Had an Embryo Transfer: A Randomized Clinical Trial
This study aimed to evaluate the effects of mandala activity combined with two different types of music on the stress and ...
Kuntai Capsules Improve Premature Ovarian Failure by Regulating AMPK-Mediated Autophagy
Kuntai Capsules Improve Premature Ovarian Failure by Regulating AMPK-Mediated Autophagy
Background: Premature ovarian failure (POF) is a gynecological endocrine disorder with current treatments having limitatio...
Melatonin Protects against LPS-Induced Mitochondrial Dyshomeostasis and Ovarian Damage through JNK Signaling Pathway in Mouse Ovary
Melatonin Protects against LPS-Induced Mitochondrial Dyshomeostasis and Ovarian Damage through JNK Signaling Pathway in Mouse Ovary
Both mitochondrial dysfunction and inflammation are closely associated with the pathogenesis of diminished ovarian reserve...
CHAF1A Promotes Preadipocyte Differentiation and Contributes to Macrosomia in Gestational Diabetes Mellitus
CHAF1A Promotes Preadipocyte Differentiation and Contributes to Macrosomia in Gestational Diabetes Mellitus
Gestational diabetes mellitus (GDM) leads to macrosomia primarily due to fat accumulation caused by adipocyte differentiat...
Development and Validation of An Interpretable Machine Learning-Based Prediction Model of Postpartum Hemorrhage in Placenta Previa Following Cesarean Section: A Multicenter Study
Development and Validation of An Interpretable Machine Learning-Based Prediction Model of Postpartum Hemorrhage in Placenta Previa Following Cesarean Section: A Multicenter Study
The objective of this study is to predict the occurrence of postpartum hemorrhage in women with placenta previa based on m...
Linking Ghrelin Elevation to Reproductive Dysfunction: Insights from Feed-Restricted Male Rats
Linking Ghrelin Elevation to Reproductive Dysfunction: Insights from Feed-Restricted Male Rats
Ghrelin, a peptide hormone consisting of 28 amino acids and primarily produced in the stomach, is crucial for stimulating ...
Reproductive Performance and Obstetric Outcomes after Hysteroscopic Metroplasty for T Shaped Uterus
Reproductive Performance and Obstetric Outcomes after Hysteroscopic Metroplasty for T Shaped Uterus
The aim of this retrospective cohort study is to investigate the impact of hysteroscopic metroplasty for T-shaped uterus o...
MyD88 Signaling in Sertoli Cells Mediates LPS-Induced Orchitis in Mice
MyD88 Signaling in Sertoli Cells Mediates LPS-Induced Orchitis in Mice
Orchitis, a prevalent male reproductive disorder that can severely impair fertility and potentially result in infertility....
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