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SCI Abstract
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Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59
Factor H and membrane inhibitor of reactive lysis (CD59) are key regulators of complement activation. Mesenchymal stem cel...
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Mesenchymal Stem Cell-Derived Extracellular Vesicles Carrying Circ-Tulp4 Attenuate Diabetes Mellitus with Nonalcoholic Fatty Liver Disease by Inhibiting Cell Pyroptosis through the HNRNPC/ABHD6 Axis
Diabetes mellitus with nonalcoholic fatty liver disease (DM-NAFLD) represents a complex metabolic syndrome with significan...
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Establishment of an In Vitro Embryo-Endometrium Model Using Alginate-Embedded Mouse Embryos and Human Embryoid Body
Embryo-endometrium cross-talk is one of the critical processes for implantation, and unsuccessful cross-talk leads to infe...
Tissue Engineering And Regenerative Medicine
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Development of Zinc-Containing Chitosan/Gelatin Coatings with Immunomodulatory Effect for Soft Tissue Sealing around Dental Implants
Soft tissue integration (STI) around dental implant abutments is a prerequisite to prevent bacterial invasion and achieve ...
Tissue Engineering And Regenerative Medicine
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Implantation of Islets Co-Seeded with Tregs in a Novel Biomaterial Reverses Diabetes in the NOD Mouse Model
Type 1 diabetes (T1D) results in autoreactive T cells chronically destroying pancreatic islets. This often results in irre...
Tissue Engineering And Regenerative Medicine
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Gingival Mesenchymal Stem Cells: A Periodontal Regenerative Substitute
Gingival mesenchymal stem cells (GMSCs) are distinctive homogenous subset of mesenchymal stem cells (MSCs), which has its ...
Tissue Engineering And Regenerative Medicine
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Efficacy of Bone Regeneration Cell Therapy Using Mesenchymal Stem Cells Originating from Embryonic Stem Cells in Animal Models; Bone Defects and Osteomyelitis
Bone defects are commonly encountered due to accidents, diseases, or aging, and the demand for effective bone regeneration...
Tissue Engineering And Regenerative Medicine
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The Application of L-Serine-Incorporated Gelatin Sponge into the Calvarial Defect of the Ovariectomized Rats
Osteoporosis, characterized by decreased bone mineral density due to an imbalance between osteoblast and osteoclast activi...
Tissue Engineering And Regenerative Medicine
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Lipid Priming of Adipose Mesenchymal Stromal Cells with Docosahexaenoic Acid: Impact on Cell Differentiation, Senescence and the Secretome Neuroregulatory Profile
Priming strategies that improve the functionality of MSCs may be required to address issues limiting successful clinical t...
Tissue Engineering And Regenerative Medicine
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Unlocking Therapeutic Potential: Camphorquinone’s Role in Alleviating Non-Alcoholic Fatty Liver Disease via SIRT1/LKB1/AMPK Pathway Activation
Non-alcoholic fatty liver disease (NAFLD) is a pathological condition that increase the risk of simple steatosis to hepato...
Tissue Engineering And Regenerative Medicine
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Rapid Video Analysis for Contraction Synchrony of Human Induced Pluripotent Stem Cells-Derived Cardiac Tissues
The contraction behaviors of cardiomyocytes (CMs), especially contraction synchrony, are crucial factors reflecting their ...
Tissue Engineering And Regenerative Medicine
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Regenerative Functions of Regulatory T Cells and Current Strategies Utilizing Mesenchymal Stem Cells in Immunomodulatory Tissue Regeneration
Regulatory T cells (Tregs) are essential for maintaining immune homeostasis and facilitating tissue regeneration by foster...
Tissue Engineering And Regenerative Medicine
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Enhancing Cardiomyocyte Purity through Lactate-Based Metabolic Selection
Direct reprogramming of fibroblasts into chemically induced cardiomyocyte-like cells (CiCMs) through small molecules prese...
Tissue Engineering And Regenerative Medicine
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Biofabricated 3D Intestinal Models as an Alternative to Animal-Based Approaches for Drug Toxicity Assays
The main challenge in new drug development is accurately predicting the human response in preclinical models. In this stud...
Tissue Engineering And Regenerative Medicine
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∆9-Tetrahydrocannabinol Increases Growth Factor Release by Cultured Adipose Stem Cells and Adipose Tissue in vivo
Because of its biocompatibility and its soft and dynamic nature, the grafting of adipose tissue is regarded an ideal techn...
Tissue Engineering And Regenerative Medicine
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Reducing Healing Period with DDM/rhBMP-2 Grafting for Early Loading in Dental Implant Surgery
Traditionally, dental implants require a healing period of 4 to 9 months for osseointegration, with longer recove...
Tissue Engineering And Regenerative Medicine
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Exosomes and Exosome-Mimetics for Atopic Dermatitis Therapy
Exosomes and exosome mimetics are used as alternatives to cell therapy. They have shown potential in treating skin disorde...
Tissue Engineering And Regenerative Medicine
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Engineering of Cell Derived-Nanovesicle as an Alternative to Exosome Therapy
Exosomes, nano-sized vesicles ranging between 30 and 150 nm secreted by human cells, play a pivotal role in long-range int...
Tissue Engineering And Regenerative Medicine
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Strategies for Constructing Tissue-Engineered Fat for Soft Tissue Regeneration
Repairing soft tissue defects caused by inflammation, tumors, and trauma remains a major challenge for surgeons. Adipose t...
Tissue Engineering And Regenerative Medicine
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Fabricating Composite Cell Sheets for Wound Healing: Cell Sheets Based on the Communication Between BMSCs and HFSCs Facilitate Full-Thickness Cutaneous Wound Healing
Insufficient angiogenesis and the lack of skin appendages are critical challenges in cutaneous wound healing. Stem cell-fa...
Tissue Engineering And Regenerative Medicine
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Modulation of 3D Bioprintability in Polysaccharide Bioink by Bioglass Nanoparticles and Multiple Metal Ions for Tissue Engineering
Bioglasses are used in applications related to bone rehabilitation and repair. The mechanical and bioactive properties of ...
Tissue Engineering And Regenerative Medicine
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Preliminary Investigation on Efficacy and Safety of Substance P-Coated Stent for Promoting Re-Endothelialization: A Porcine Coronary Artery Restenosis Model
Current polymer-based drug-eluting stents (DESs) have fundamental issues about inflammation and delayed re-endothelializat...
Tissue Engineering And Regenerative Medicine
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Ascorbic Acid 2-Phosphate Releasing Supercritically Foamed Porous Poly-L-Lactide-Co-ε-Caprolactone Scaffold Enhances the Collagen Production of Human Vaginal Stromal Cells: A New Approach for Vaginal Tissue Engineering
The reconstructive surgery of vaginal defects is highly demanding and susceptible to complications, especially in larger d...
Tissue Engineering And Regenerative Medicine
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Alternative Biological Material for Tissue Engineering of the Vagina: Porcine-Derived Acellular Vaginal Matrix
Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a severe congenital disorder characterized by vaginal hypoplasia ca...
Tissue Engineering And Regenerative Medicine
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Correction to: Nitrosylation of β2-Tubulin Promotes Microtubule Disassembly and Differentiated Cardiomyocyte Beating in Ischemic Mice
Department of Biological Sciences and Biotechnology, School of Biological Sciences, College of Natural Sciences, Chungbuk ...
Tissue Engineering And Regenerative Medicine
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Photobiomodulation Facilitates Rat Cutaneous Wound Healing by Promoting Epidermal Stem Cells and Hair Follicle Stem Cells Proliferation
Cutaneous wound healing represents a common fundamental phenomenon requiring the participation of cells of distin...
Tissue Engineering And Regenerative Medicine
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Understanding the Multi-Functional Role of TCTP in the Regeneration Process of Earthworm, Perionyx excavatus
Regeneration is a highly complex process that requires the coordination of numerous molecular events, and identifying the ...
Tissue Engineering And Regenerative Medicine
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A Review of the Role of Bioreactors for iPSCs-Based Tissue-Engineered Articular Cartilage
Osteoarthritis (OA) is the most common degenerative joint disease without an ultimate treatment. In a search for novel app...
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PVA/PVP Nanofibres Incorporated with Ecklonia cava Phlorotannins Exhibit Excellent Cytocompatibility and Accelerate Hyperglycaemic Wound Healing
Diabetic foot ulcer (DFU) is a major debilitating complication of diabetes. The lack of effective diabetic wound dressings...
Tissue Engineering And Regenerative Medicine
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Atelocollagen Scaffold Enhances Cartilage Regeneration in Osteochondral Defects: A Study in Rabbits
To enhance articular cartilage healing, microfractures (Mfx) and bone marrow aspirate concentrate (BMAC) are commonly used...
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