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Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59
Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59
Factor H and membrane inhibitor of reactive lysis (CD59) are key regulators of complement activation. Mesenchymal stem cel...
Establishment of an In Vitro Embryo-Endometrium Model Using Alginate-Embedded Mouse Embryos and Human Embryoid Body
Establishment of an In Vitro Embryo-Endometrium Model Using Alginate-Embedded Mouse Embryos and Human Embryoid Body
Embryo-endometrium cross-talk is one of the critical processes for implantation, and unsuccessful cross-talk leads to infe...
Implantation of Islets Co-Seeded with Tregs in a Novel Biomaterial Reverses Diabetes in the NOD Mouse Model
Implantation of Islets Co-Seeded with Tregs in a Novel Biomaterial Reverses Diabetes in the NOD Mouse Model
Type 1 diabetes (T1D) results in autoreactive T cells chronically destroying pancreatic islets. This often results in irre...
Gingival Mesenchymal Stem Cells: A Periodontal Regenerative Substitute
Gingival Mesenchymal Stem Cells: A Periodontal Regenerative Substitute
Gingival mesenchymal stem cells (GMSCs) are distinctive homogenous subset of mesenchymal stem cells (MSCs), which has its ...
The Application of L-Serine-Incorporated Gelatin Sponge into the Calvarial Defect of the Ovariectomized Rats
The Application of L-Serine-Incorporated Gelatin Sponge into the Calvarial Defect of the Ovariectomized Rats
Osteoporosis, characterized by decreased bone mineral density due to an imbalance between osteoblast and osteoclast activi...
Rapid Video Analysis for Contraction Synchrony of Human Induced Pluripotent Stem Cells-Derived Cardiac Tissues
Rapid Video Analysis for Contraction Synchrony of Human Induced Pluripotent Stem Cells-Derived Cardiac Tissues
The contraction behaviors of cardiomyocytes (CMs), especially contraction synchrony, are crucial factors reflecting their ...
Enhancing Cardiomyocyte Purity through Lactate-Based Metabolic Selection
Enhancing Cardiomyocyte Purity through Lactate-Based Metabolic Selection
Direct reprogramming of fibroblasts into chemically induced cardiomyocyte-like cells (CiCMs) through small molecules prese...
Biofabricated 3D Intestinal Models as an Alternative to Animal-Based Approaches for Drug Toxicity Assays
Biofabricated 3D Intestinal Models as an Alternative to Animal-Based Approaches for Drug Toxicity Assays
The main challenge in new drug development is accurately predicting the human response in preclinical models. In this stud...
∆9-Tetrahydrocannabinol Increases Growth Factor Release by Cultured Adipose Stem Cells and Adipose Tissue in vivo
∆9-Tetrahydrocannabinol Increases Growth Factor Release by Cultured Adipose Stem Cells and Adipose Tissue in vivo
Because of its biocompatibility and its soft and dynamic nature, the grafting of adipose tissue is regarded an ideal techn...
Reducing Healing Period with DDM/rhBMP-2 Grafting for Early Loading in Dental Implant Surgery
Reducing Healing Period with DDM/rhBMP-2 Grafting for Early Loading in Dental Implant Surgery
Traditionally, dental implants require a healing period of 4 to 9 months for osseointegration, with longer recove...
Exosomes and Exosome-Mimetics for Atopic Dermatitis Therapy
Exosomes and Exosome-Mimetics for Atopic Dermatitis Therapy
Exosomes and exosome mimetics are used as alternatives to cell therapy. They have shown potential in treating skin disorde...
Engineering of Cell Derived-Nanovesicle as an Alternative to Exosome Therapy
Engineering of Cell Derived-Nanovesicle as an Alternative to Exosome Therapy
Exosomes, nano-sized vesicles ranging between 30 and 150 nm secreted by human cells, play a pivotal role in long-range int...
Strategies for Constructing Tissue-Engineered Fat for Soft Tissue Regeneration
Strategies for Constructing Tissue-Engineered Fat for Soft Tissue Regeneration
Repairing soft tissue defects caused by inflammation, tumors, and trauma remains a major challenge for surgeons. Adipose t...
Alternative Biological Material for Tissue Engineering of the Vagina: Porcine-Derived Acellular Vaginal Matrix
Alternative Biological Material for Tissue Engineering of the Vagina: Porcine-Derived Acellular Vaginal Matrix
Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a severe congenital disorder characterized by vaginal hypoplasia ca...
Understanding the Multi-Functional Role of TCTP in the Regeneration Process of Earthworm, Perionyx excavatus
Understanding the Multi-Functional Role of TCTP in the Regeneration Process of Earthworm, Perionyx excavatus
Regeneration is a highly complex process that requires the coordination of numerous molecular events, and identifying the ...
A Review of the Role of Bioreactors for iPSCs-Based Tissue-Engineered Articular Cartilage
A Review of the Role of Bioreactors for iPSCs-Based Tissue-Engineered Articular Cartilage
Osteoarthritis (OA) is the most common degenerative joint disease without an ultimate treatment. In a search for novel app...
Atelocollagen Scaffold Enhances Cartilage Regeneration in Osteochondral Defects: A Study in Rabbits
Atelocollagen Scaffold Enhances Cartilage Regeneration in Osteochondral Defects: A Study in Rabbits
To enhance articular cartilage healing, microfractures (Mfx) and bone marrow aspirate concentrate (BMAC) are commonly used...