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Overexpression of the NEK8 kinase inhibits homologous recombination
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MCM8/9 and FANCD2 interact within a shared pathway in response to replication stress caused by DNA crosslinks
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Lets talk about ataxia-telangiectasia: Meeting report of the AT clinical research conference June 2025
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DNA damage response and its clinical implications in pediatric cancers
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Modulation of OGG1 enzymatic activity by the cellular machinery – have all the boxes been ticked?
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Base excision repair in chromatin: A tug-of-war for DNA damage
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Overcoming natural replication barriers formed by DNA structures and the role of repositioning to the nuclear periphery
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DNA G-quadruplexes: Structural and functional insights
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Recent advances in understanding the molecular mechanisms of SLX4 recruitment in the replication stress response
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Fueling for the finish line: Control of human telomerase activity by nucleotide metabolism
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How DNA secondary structures drive replication fork instability
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Stepwise DNA Damage and Repair Mechanisms at Replication Forks in Response to Topoisomerase I Inhibition
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The effect of methylation and hydroxymethylation of cytosine on activity and fidelity of Pol λ and Pol β
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Targeting dePARylation in cancer therapy
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Role of NEIL1 in genome maintenance
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The hidden elephant: Modified abasic sites and their consequences
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Obituary: Francis Fabre (1940–2024): Yeast geneticist that contributed to our understanding of the control of homologous recombination
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Weaponizing CRISPR/Cas9 for selective elimination of cells with an aberrant genome
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Reversible association of ubiquitin with PCNA is important for template switching in S. cerevisiae
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Transport of DNA repair proteins to the cell nucleus by the classical nuclear importin pathway – a structural overview
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The differential roles of rad9 alternatively spliced forms in double- strand DNA break repair during Drosophila meiosis
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Stained DNA Dot Detection (SD3): An automated tool for quantifying fluorescent features along single stretched DNA molecules
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Temporal and spatial dynamics of DNA double-strand break repair centers
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Identification of a novel pathogenic XPC:c.2420 + 1 G>C variant in a patient with xeroderma pigmentosum
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The replication stress response: Mechanisms and functions
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Werner helicase as a therapeutic target in mismatch repair deficient colorectal cancer
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Building an integrated view of R-loops, transcription, and chromatin
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Role of HSP40 proteins in genome maintenance, insulin signaling and cancer therapy
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Modulation of OGG1 enzymatic activities by small molecules, promising tools and current challenges
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