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Pressure applied: Mechanisms affecting heart–lung interactions and cardiac filling in patients with HFpEF during rest and exercise
Pressure applied: Mechanisms affecting heart–lung interactions and cardiac filling in patients with HFpEF during rest and exercise
Heart failure with preserved ejection fraction (HFpEF) is characterized by elevated left-ventricular (LV) filling pressure...
Transthyretin cardiac amyloidosis: advances and ambiguities
Transthyretin cardiac amyloidosis: advances and ambiguities
Cardiac amyloidosis is a fatal disorder caused by deposition of abnormally folded protein in the interstitial space. One o...
Infective endocarditis complicated by shock: a systematic review and meta-analysis
Infective endocarditis complicated by shock: a systematic review and meta-analysis
Infective endocarditis (IE) complicated by septic or cardiogenic shock is linked to a marked increase in morbidity and mor...
Pharmacological options to relieve congestion in acute heart failure
Pharmacological options to relieve congestion in acute heart failure
Although congestion is present in the large majority of patients hospitalized with acute heart failure (AHF), the pharmaco...
Hypertensive acute heart failure: a critical perspective on definition, epidemiology, pathophysiology, and prognosis—a narrative review: a joint session with the Romanian Society of Cardiology (part II)
Hypertensive acute heart failure: a critical perspective on definition, epidemiology, pathophysiology, and prognosis—a narrative review: a joint session with the Romanian Society of Cardiology (part II)
Hypertensive acute heart failure (HT-AHF) has historically been recognized as a distinct clinical phenotype of AHF, charac...
Cardiac resynchronization therapy in cancer patients with chemotherapy-induced cardiomyopathy: a mini review
Cardiac resynchronization therapy in cancer patients with chemotherapy-induced cardiomyopathy: a mini review
Chemotherapy-induced cardiomyopathy (CHIC) represents a growing clinical challenge due to the increasing use of cardiotoxi...
Hypoalbuminemia in heart failure: pathophysiology, clinical implications, and management strategies
Hypoalbuminemia in heart failure: pathophysiology, clinical implications, and management strategies
Hypoalbuminemia is commonly seen in patients with heart failure and is associated with worse outcomes. Multiple pathophysi...
Polypill in heart failure: a pathway to simplified treatment and improved adherence and outcomes
Polypill in heart failure: a pathway to simplified treatment and improved adherence and outcomes
Heart failure (HF) remains a global health challenge that imposes significant clinical and economic burden. Treatment adhe...
Evaluation of pulmonary hypertension in heart failure with preserved ejection fraction
Evaluation of pulmonary hypertension in heart failure with preserved ejection fraction
In contemporary clinical practice, pulmonary hypertension (PH) is most commonly caused by heart failure with preserved eje...
Cardiac rehabilitation in patients with heart failure: clinical recommendation based on a review of the evidence
Cardiac rehabilitation in patients with heart failure: clinical recommendation based on a review of the evidence
Cardiac rehabilitation (CR) is a comprehensive, multidisciplinary approach that combines exercise training, risk factor ma...
Lung ultrasound in cardiac rehabilitation: expert consensus on protocols, clinical use, and integration into patient management from the working group on cardiac rehabilitation and cardiovascular prevention of the Italian society of cardiology
Lung ultrasound in cardiac rehabilitation: expert consensus on protocols, clinical use, and integration into patient management from the working group on cardiac rehabilitation and cardiovascular prevention of the Italian society of cardiology
Lung ultrasonography (LUS) is a reliable and reproducible tool across various clinical settings. Its high diagnostic accur...
Heart failure and left ventricular ejection fraction: a necessary but imperfect partnership
Heart failure and left ventricular ejection fraction: a necessary but imperfect partnership
The left ventricular ejection fraction (LVEF) is the most commonly used index to assess left ventricular systolic function...
Diabetic cardiomyopathy: Mechanistic insights on molecular pathways and emerging therapeutic approaches
Diabetic cardiomyopathy: Mechanistic insights on molecular pathways and emerging therapeutic approaches
Diabetes and its complications represent a global burden to human health. Among diabetic microvascular and macrovascular c...
Phenotype-guided approach for device-based therapies in heart failure
Phenotype-guided approach for device-based therapies in heart failure
Device-based therapies have become integral in the management of heart failure (HF). By targeting structural or neurohormo...
Navigating heart failure: a plain-language summary to empower people with heart failure
Navigating heart failure: a plain-language summary to empower people with heart failure
Heart failure is a chronic condition that can result from multiple causes and occurs when the heart cannot pump enough blo...
Heart failure and chronic obstructive pulmonary disease. A combination not to be underestimated
Heart failure and chronic obstructive pulmonary disease. A combination not to be underestimated
Chronic obstructive pulmonary disease (COPD) and heart failure (HF) frequently coexist and interact through complex and bi...
The challenges of using electronic medical records (EMR) to facilitate guideline-directed medical therapy (GDMT) for patients with heart failure (HF) and chronic kidney disease (CKD)
The challenges of using electronic medical records (EMR) to facilitate guideline-directed medical therapy (GDMT) for patients with heart failure (HF) and chronic kidney disease (CKD)
Heart failure (HF) and chronic kidney disease (CKD) are prevalent comorbidities that significantly impact patient outcomes...
Special topics: heart failure–related cardiogenic shock, valvular heart disease and end-stage renal disease. Part 4 of the International Expert Opinion Series on Acute Heart Failure Management
Special topics: heart failure–related cardiogenic shock, valvular heart disease and end-stage renal disease. Part 4 of the International Expert Opinion Series on Acute Heart Failure Management
Acute heart failure (AHF) remains a major global health challenge, contributing significantly to morbidity, mortality, and...
Echocardiographic monitoring in cancer therapy: clinical guidance for cardiologists and oncologists
Echocardiographic monitoring in cancer therapy: clinical guidance for cardiologists and oncologists
Transthoracic echocardiography has a central role in the diagnosis and monitoring of cancer therapy-related cardiac dysfun...
A STRONG call for intensive oral heart failure therapy in acute heart failure patients
A STRONG call for intensive oral heart failure therapy in acute heart failure patients
Heart failure (HF), a chronic and progressive disease, is increasing in prevalence worldwide and is associated with increa...
Left atrial shunting devices: why, what, how, and… when?
Left atrial shunting devices: why, what, how, and… when?
Left atrial (LA) hypertension is central in the pathophysiology of heart failure (HF) in general and of HF with preserved ...
Renal denervation in the setting of heart failure
Renal denervation in the setting of heart failure
Renal Denervation (RDN) has emerged over the last decade as a third pillar in the treatment of arterial hypertension, alon...
Sodium zirconium cyclosilicate for MRAs optimization in HFrEF: lessons learned from the REALIZE-K trial
Sodium zirconium cyclosilicate for MRAs optimization in HFrEF: lessons learned from the REALIZE-K trial
Mineralocorticoid receptor antagonists (MRAs) are a cornerstone of guideline-directed medical therapy for heart failure wi...
Positron emission tomography in cardiac amyloidosis: current evidence and future directions
Positron emission tomography in cardiac amyloidosis: current evidence and future directions
The increasing recognition of cardiac amyloidosis (CA) as a cause of heart failure, coupled with advancements in therapeut...
Tricuspid regurgitation after heart transplantation: where innovation and intervention are in hibernation
Tricuspid regurgitation after heart transplantation: where innovation and intervention are in hibernation
Tricuspid regurgitation (TR) is a common valvular dysfunction following heart transplantation (HT), with reported prevalen...
Closing the GDMT gap: insights from PHARM-HF A&F on the role of pharmacists in heart failure care
Closing the GDMT gap: insights from PHARM-HF A&F on the role of pharmacists in heart failure care
This focused review examines the results of the PHARM-HF A&F Study, a randomized trial evaluating audit and feedba...
Worsening heart failure: progress, pitfalls, and perspectives
Worsening heart failure: progress, pitfalls, and perspectives
For most patients with chronic heart failure (HF), the clinical course of the disease includes periods of apparent clinica...
Myeloperoxidase inhibition in the landscape of anti-inflammatory therapies for heart failure with preserved ejection fraction: the ENDEAVOR trial
Myeloperoxidase inhibition in the landscape of anti-inflammatory therapies for heart failure with preserved ejection fraction: the ENDEAVOR trial
Systemic inflammation is considered one of the key physiological drivers in heart failure with preserved ejection fraction...
Emerging, novel gene-modulating therapies for transthyretin amyloid cardiomyopathy
Emerging, novel gene-modulating therapies for transthyretin amyloid cardiomyopathy
Transthyretin amyloid cardiomyopathy (ATTR-CM) is a progressive, life-threatening disease caused by the pathological depos...
Cirrhotic cardiomyopathy: comprehensive insights into pathophysiology, diagnosis, and management
Cirrhotic cardiomyopathy: comprehensive insights into pathophysiology, diagnosis, and management
Cirrhotic cardiomyopathy (CCM) is a cardiac dysfunction linked to chronic liver disease, primarily characterized by impair...
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