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A STRONG call for intensive oral heart failure therapy in acute heart failure patients
A STRONG call for intensive oral heart failure therapy in acute heart failure patients
Heart failure (HF), a chronic and progressive disease, is increasing in prevalence worldwide and is associated with increa...
Left atrial shunting devices: why, what, how, and… when?
Left atrial shunting devices: why, what, how, and… when?
Left atrial (LA) hypertension is central in the pathophysiology of heart failure (HF) in general and of HF with preserved ...
Renal denervation in the setting of heart failure
Renal denervation in the setting of heart failure
Renal Denervation (RDN) has emerged over the last decade as a third pillar in the treatment of arterial hypertension, alon...
Sodium zirconium cyclosilicate for MRAs optimization in HFrEF: lessons learned from the REALIZE-K trial
Sodium zirconium cyclosilicate for MRAs optimization in HFrEF: lessons learned from the REALIZE-K trial
Mineralocorticoid receptor antagonists (MRAs) are a cornerstone of guideline-directed medical therapy for heart failure wi...
Positron emission tomography in cardiac amyloidosis: current evidence and future directions
Positron emission tomography in cardiac amyloidosis: current evidence and future directions
The increasing recognition of cardiac amyloidosis (CA) as a cause of heart failure, coupled with advancements in therapeut...
Tricuspid regurgitation after heart transplantation: where innovation and intervention are in hibernation
Tricuspid regurgitation after heart transplantation: where innovation and intervention are in hibernation
Tricuspid regurgitation (TR) is a common valvular dysfunction following heart transplantation (HT), with reported prevalen...
Closing the GDMT gap: insights from PHARM-HF A&F on the role of pharmacists in heart failure care
Closing the GDMT gap: insights from PHARM-HF A&F on the role of pharmacists in heart failure care
This focused review examines the results of the PHARM-HF A&F Study, a randomized trial evaluating audit and feedba...
Worsening heart failure: progress, pitfalls, and perspectives
Worsening heart failure: progress, pitfalls, and perspectives
For most patients with chronic heart failure (HF), the clinical course of the disease includes periods of apparent clinica...
Myeloperoxidase inhibition in the landscape of anti-inflammatory therapies for heart failure with preserved ejection fraction: the ENDEAVOR trial
Myeloperoxidase inhibition in the landscape of anti-inflammatory therapies for heart failure with preserved ejection fraction: the ENDEAVOR trial
Systemic inflammation is considered one of the key physiological drivers in heart failure with preserved ejection fraction...
Emerging, novel gene-modulating therapies for transthyretin amyloid cardiomyopathy
Emerging, novel gene-modulating therapies for transthyretin amyloid cardiomyopathy
Transthyretin amyloid cardiomyopathy (ATTR-CM) is a progressive, life-threatening disease caused by the pathological depos...
Cirrhotic cardiomyopathy: comprehensive insights into pathophysiology, diagnosis, and management
Cirrhotic cardiomyopathy: comprehensive insights into pathophysiology, diagnosis, and management
Cirrhotic cardiomyopathy (CCM) is a cardiac dysfunction linked to chronic liver disease, primarily characterized by impair...
Mechanisms of exercise intolerance in heart failure with preserved ejection fraction (HFpEF)
Mechanisms of exercise intolerance in heart failure with preserved ejection fraction (HFpEF)
Exercise intolerance is a well-established symptom of heart failure with preserved ejection fraction (HFpEF) and is associ...
Leptin and heart failure: the chicken or the egg?
Leptin and heart failure: the chicken or the egg?
Leptin plays a dual role in heart failure (HF), acting as either a primary driver or a secondary phenomenon depending on t...
Heart and brain interactions in heart failure: pathophysiological mechanisms and clinical perspectives
Heart and brain interactions in heart failure: pathophysiological mechanisms and clinical perspectives
Heart failure (HF) is a complex and debilitating syndrome that affects millions of people worldwide. In addition to the sy...
Electronic health record nudges to optimize guideline-directed medical therapy for heart failure
Electronic health record nudges to optimize guideline-directed medical therapy for heart failure
Electronic health record (EHR) alert nudges are emerging as a valuable tool for improving heart failure (HF) management, p...
Chronic venous insufficiency in heart failure: exploring a reciprocal influence on cardiovascular health
Chronic venous insufficiency in heart failure: exploring a reciprocal influence on cardiovascular health
Chronic venous insufficiency (CVI) is a prevalent disorder, arising from venous valve incompetence and vein wall weakness,...
The application of neighborhood area deprivation index to improve health equity across the spectrum of heart failure: a review
The application of neighborhood area deprivation index to improve health equity across the spectrum of heart failure: a review
Neighborhood environments play a key role in the development of individual risk factors for heart failure (HF) and impact ...
Echocardiographic manifestations in end-stage renal disease
Echocardiographic manifestations in end-stage renal disease
End-stage renal disease (ESRD) is a common but profound clinical condition, and it is associated with extremely increased ...
Correction to: Adverse effects of sodium‑glucose cotransporter‑2 inhibitors in patients with heart failure: a systematic review and meta‑analysis
Correction to: Adverse effects of sodium‑glucose cotransporter‑2 inhibitors in patients with heart failure: a systematic review and meta‑analysis
Cardiology Division, Valduce Hospital, Como, ItalyA. Pozzi & G. CorradoCardiology Division, Papa Giovanni XXIII Hospit...
Multidisciplinary approach in cardiomyopathies: From genetics to advanced imaging
Multidisciplinary approach in cardiomyopathies: From genetics to advanced imaging
Cardiomyopathies are myocardial diseases characterized by mechanical and electrical dysfunction of the heart muscle which ...
Can the hemodynamic model in heart failure be restored based on analysis of ventricular-arterial coupling?
Can the hemodynamic model in heart failure be restored based on analysis of ventricular-arterial coupling?
The hemodynamic model was inappropriate to explain the disappointing effect of vasodilation and the beneficial effect of b...
Pulmonary hypertension secondary to valvular heart disease: a state-of-the-art review
Pulmonary hypertension secondary to valvular heart disease: a state-of-the-art review
Pulmonary hypertension (PH) is a common disease affecting up to 1% of the population and at least 50% of patients diagnose...
Sex-specific differences in risk factors, comorbidities, diagnostic challenges, optimal management, and prognostic outcomes of heart failure with preserved ejection fraction: A comprehensive literature review
Sex-specific differences in risk factors, comorbidities, diagnostic challenges, optimal management, and prognostic outcomes of heart failure with preserved ejection fraction: A comprehensive literature review
Due to hormonal variations, heart failure with preserved ejection fraction (HFpEF) remains prevalent in women and affects ...
Large animal models to study effectiveness of therapy devices in the treatment of heart failure with preserved ejection fraction (HFpEF)
Large animal models to study effectiveness of therapy devices in the treatment of heart failure with preserved ejection fraction (HFpEF)
Our understanding of the complex pathophysiology of Heart failure with preserved ejection fraction (HFpEF) is limited by t...
Clinical staging of Anderson-Fabry cardiomyopathy: An operative proposal
Clinical staging of Anderson-Fabry cardiomyopathy: An operative proposal
As a slowly progressive form of hypertrophic cardiomyopathy (HCM), Anderson-Fabry disease (FD) resembles the phenotype of ...
Adverse effects of sodium-glucose cotransporter-2 inhibitors in patients with heart failure: a systematic review and meta-analysis
Adverse effects of sodium-glucose cotransporter-2 inhibitors in patients with heart failure: a systematic review and meta-analysis
Sodium-glucose cotransoporter-2 inhibitors (SGLT-2Is) improve prognosis in heart failure (HF) patients both with reduced e...
Device therapy for patients with atrial fibrillation and heart failure with preserved ejection fraction
Device therapy for patients with atrial fibrillation and heart failure with preserved ejection fraction
Device therapy is a nonpharmacological approach that presents a crucial advancement for managing patients with atrial fibr...
Advancing cardiac regeneration through 3D bioprinting: methods, applications, and future directions
Advancing cardiac regeneration through 3D bioprinting: methods, applications, and future directions
Cardiovascular diseases (CVDs) represent a paramount global mortality concern, and their prevalence is on a relentless asc...
Outcomes of left-sided heart valve surgery after heart transplantation: a systematic review
Outcomes of left-sided heart valve surgery after heart transplantation: a systematic review
As the survival after heart transplantation (HTx) is steadily improving, an increasing number of patients with late cardia...
Correction to: Diagnosis of heart failure with preserved ejection fraction: a systematic narrative review of the evidence
Correction to: Diagnosis of heart failure with preserved ejection fraction: a systematic narrative review of the evidence
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
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