McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M, Burri H, Butler J, Čelutkienė J, Chioncel O, Cleland JGF, Crespo-Leiro MG, Farmakis D, Gilard M, Heymans S, Hoes AW, Jaarsma T, Jankowska EA, Lainscak M, Lam CSP, Lyon AR, McMurray JJV, Mebazaa A, Mindham R, Muneretto C, Francesco Piepoli M, Price S, Rosano GMC, Ruschitzka F, Skibelund AK, ESC Scientific Document Group (2024) 2023 focused update of the 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: developed by the task force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) With the special contribution of the Heart Failure Association (HFA) of the ESC. Eur J Heart Fail. 26(1):5–17. https://doi.org/10.1002/ejhf.3024

Article  PubMed  Google Scholar 

Baratto C, Caravita S, Soranna D, Dewachter C, Bondue A, Zambon A, Badano LP, Parati G, Vachiéry JL (2022) Exercise haemodynamics in heart failure with preserved ejection fraction: a systematic review and meta-analysis. ESC Heart Fail. 9(5):3079–3091. https://doi.org/10.1002/ehf2.13979. (Erratum in: ESC Heart Fail. 2023 Jun;10(3):2144)

Article  PubMed  PubMed Central  Google Scholar 

Edward JA, Parker H, Stöhr EJ, McDonnell BJ, O’Gean K, Schulte M, Lawley JS, Cornwell WK (2023) Exertional cardiac and pulmonary vascular hemodynamics in patients with heart failure with reduced ejection fraction. J Card Fail. 29(9):1276–1284. https://doi.org/10.1016/j.cardfail.2023.01.010

Article  PubMed  PubMed Central  Google Scholar 

Borlaug BA, Nishimura RA, Sorajja P, Lam CS, Redfield MM (2010) Exercise hemodynamics enhance diagnosis of early heart failure with preserved ejection fraction. Circ Heart Fail. 3(5):588–95. https://doi.org/10.1161/CIRCHEARTFAILURE.109.930701

Article  PubMed  PubMed Central  Google Scholar 

Baratto C, Caravita S, Soranna D, Dewachter C, Bondue A, Zambon A, Badano LP, Parati G, Vachiéry JL (2022) An updated meta-analysis of hemodynamics markers of prognosis in patients with pulmonary hypertension due to left heart disease. Pulm Circ 12(4):e12145. https://doi.org/10.1002/pul2.12145

Article  CAS  PubMed  PubMed Central  Google Scholar 

Reddy YNV, Obokata M, Wiley B, Koepp KE, Jorgenson CC, Egbe A, Melenovsky V, Carter RE, Borlaug BA (2019) The haemodynamic basis of lung congestion during exercise in heart failure with preserved ejection fraction. Eur Heart J 40(45):3721–3730. https://doi.org/10.1093/eurheartj/ehz713

Article  CAS  PubMed  PubMed Central  Google Scholar 

Caravita S, Dewachter C, Soranna D, D’Araujo SC, Khaldi A, Zambon A, Parati G, Bondue A, Vachiéry JL (2018) Haemodynamics to predict outcome in pulmonary hypertension due to left heart disease: a meta-analysis. Eur Respir J 51(4):1702427. https://doi.org/10.1183/13993003.02427-2017

Article  PubMed  Google Scholar 

Baratto C, Caravita S, Dewachter C, Faini A, Perego GB, Bondue A, Senni M, Muraru D, Badano LP, Parati G, Vachiéry JL (2023) Right heart adaptation to exercise in pulmonary hypertension: an invasive hemodynamic study. J Card Fail 29(9):1261–1272. https://doi.org/10.1016/j.cardfail.2023.04.009

Article  PubMed  Google Scholar 

Baratto C, Caravita S, Vachiéry JL (2023) Pulmonary hypertension associated with left heart disease. Semin Respir Crit Care Med 44(6):810–825. https://doi.org/10.1055/s-0043-1772754

Article  PubMed  Google Scholar 

Mishra S, Kass DA (2021) Cellular and molecular pathobiology of heart failure with preserved ejection fraction. Nat Rev Cardiol. 18(6):400–423. https://doi.org/10.1038/s41569-020-00480-6. (Erratum in: Nat Rev Cardiol. 2021 Jan 21)

Article  PubMed  PubMed Central  Google Scholar 

Reddy YNV, El-Sabbagh A, Nishimura RA (2018) Comparing pulmonary arterial wedge pressure and left ventricular end diastolic pressure for assessment of left-sided filling pressures. JAMA Cardiol 3(6):453–454. https://doi.org/10.1001/jamacardio.2018.0318

Article  PubMed  Google Scholar 

De la Lutembacher R (1916) stenose mitrale avec communication interauriculaire. Arch Mal Coeur 9:237–260

Google Scholar 

Ewert P, Berger F, Nagdyman N, Kretschmar O, Dittrich S, Abdul-Khaliq H, Lange P (2001) Masked left ventricular restriction in elderly patients with atrial septal defects: a contraindication for closure? Catheter Cardiovasc Interv 52(2):177–180. https://doi.org/10.1002/1522-726x(200102)52:2%3c177::aid-ccd1043%3e3.0.co;2-g

Article  CAS  PubMed  Google Scholar 

Kaye D, Shah SJ, Borlaug BA, Gustafsson F, Komtebedde J, Kubo S, Magnin C, Maurer MS, Feldman T, Burkhoff D (2014) Effects of an interatrial shunt on rest and exercise hemodynamics: results of a computer simulation in heart failure. J Card Fail 20(3):212–221. https://doi.org/10.1016/j.cardfail.2014.01.005

Article  PubMed  Google Scholar 

Søndergaard L, Reddy V, Kaye D, Malek F, Walton A, Mates M, Franzen O, Neuzil P, Ihlemann N, Gustafsson F (2014) Transcatheter treatment of heart failure with preserved or mildly reduced ejection fraction using a novel interatrial implant to lower left atrial pressure. Eur J Heart Fail 16(7):796–801. https://doi.org/10.1002/ejhf.111

Article  PubMed  Google Scholar 

Hasenfuß G, Hayward C, Burkhoff D, Silvestry FE, McKenzie S, Gustafsson F, Malek F, Van der Heyden J, Lang I, Petrie MC, Cleland JG, Leon M, Kaye DM, REDUCE LAP-HF study investigators (2016) A transcatheter intracardiac shunt device for heart failure with preserved ejection fraction (REDUCE LAP-HF): a multicentre, open-label, single-arm, phase 1 trial. Lancet 387(10025):1298–304. https://doi.org/10.1016/S0140-6736(16)00704-2

Article  PubMed  Google Scholar 

Kaye DM, Hasenfuß G, Neuzil P, Post MC, Doughty R, Trochu JN, Kolodziej A, Westenfeld R, Penicka M, Rosenberg M, Walton A, Muller D, Walters D, Hausleiter J, Raake P, Petrie MC, Bergmann M, Jondeau G, Feldman T, Veldhuisen DJ, Ponikowski P, Silvestry FE, Burkhoff D, Hayward C (2016) One-year outcomes after transcatheter insertion of an interatrial shunt device for the management of heart failure with preserved ejection fraction. Circ Heart Fail 9(12):e003662. https://doi.org/10.1161/CIRCHEARTFAILURE.116.003662

Article  PubMed  PubMed Central  Google Scholar 

Feldman T, Mauri L, Kahwash R, Litwin S, Ricciardi MJ, van der Harst P, Penicka M, Fail PS, Kaye DM, Petrie MC, Basuray A, Hummel SL, Forde-McLean R, Nielsen CD, Lilly S, Massaro JM, Burkhoff D, Shah SJ, REDUCE LAP-HF I Investigators and Study Coordinators (2018) Transcatheter interatrial shunt device for the treatment of heart failure with preserved ejection fraction (REDUCE LAP-HF I [reduce elevated left atrial pressure in patients with heart failure]): a phase 2, randomized, sham-controlled trial. Circulation 137(4):364–375. https://doi.org/10.1161/CIRCULATIONAHA.117.032094

Article  PubMed  Google Scholar 

Shah SJ, Feldman T, Ricciardi MJ, Kahwash R, Lilly S, Litwin S, Nielsen CD, van der Harst P, Hoendermis E, Penicka M, Bartunek J, Fail PS, Kaye DM, Walton A, Petrie MC, Walker N, Basuray A, Yakubov S, Hummel SL, Chetcuti S, Forde-McLean R, Herrmann HC, Burkhoff D, Massaro JM, Cleland JGF, Mauri L (2018) One-year safety and clinical outcomes of a transcatheter interatrial shunt device for the treatment of heart failure with preserved ejection fraction in the reduce elevated left atrial pressure in patients with heart failure (REDUCE LAP-HF I) trial: a randomized clinical trial. JAMA Cardiol 3(10):968–977. https://doi.org/10.1001/jamacardio.2018.2936

Article  PubMed  PubMed Central  Google Scholar 

Shah SJ, Borlaug BA, Chung ES, Cutlip DE, Debonnaire P, Fail PS, Gao Q, Hasenfuß G, Kahwash R, Kaye DM, Litwin SE, Lurz P, Massaro JM, Mohan RC, Ricciardi MJ, Solomon SD, Sverdlov AL, Swarup V, van Veldhuisen DJ, Winkler S, Leon MB, REDUCE LAP-HF II investigators (2022) Atrial shunt device for heart failure with preserved and mildly reduced ejection fraction (REDUCE LAP-HF II): a randomised, multicentre, blinded, sham-controlled trial. Lancet 399(10330):1130–1140. https://doi.org/10.1016/S0140-6736(22)00016-2

Article  PubMed  Google Scholar 

Borlaug BA, Blair J, Bergmann MW, Bugger H, Burkhoff D, Bruch L, Celermajer DS, Claggett B, Cleland JGF, Cutlip DE, Dauber I, Eicher JC, Gao Q, Gorter TM, Gustafsson F, Hayward C, van der Heyden J, Hasenfuß G, Hummel SL, Kaye DM, Komtebedde J, Massaro JM, Mazurek JA, McKenzie S, Mehta SR, Petrie MC, Post MC, Nair A, Rieth A, Silvestry FE, Solomon SD, Trochu JN, Van Veldhuisen DJ, Westenfeld R, Leon MB, Shah SJ, REDUCE LAP-HF-II Investigators (2022) Latent pulmonary vascular disease may alter the response to therapeutic atrial shunt device in heart failure. Circulation. 145(21):1592–1604. https://doi.org/10.1161/CIRCULATIONAHA.122.059486. (Erratum in: Circulation. 2022 Jul 26;146(4):e12)

Article  CAS  PubMed  PubMed Central  Google Scholar 

Caravita S, Baratto C, Filippo A, Soranna D, Dewachter C, Zambon A, Perego GB, Muraru D, Senni M, Badano LP, Parati G, Vachiéry JL, Fudim M (2023) Shedding light on latent pulmonary vascular disease in heart failure with preserved ejection fraction. JACC Heart Fail 11(10):1427–1438. https://doi.org/10.1016/j.jchf.2023.03.003

Article  CAS  PubMed  Google Scholar 

Obokata M, Reddy YNV, Melenovsky V, Pislaru S, Borlaug BA (2019) Deterioration in right ventricular structure and function over time in patients with heart failure and preserved ejection fraction. Eur Heart J 40(8):689–697. https://doi.org/10.1093/eurheartj/ehy809

Article  PubMed  Google Scholar 

Patel RB, Silvestry FE, Komtebedde J, Solomon SD, Hasenfuß G, Litwin SE, Borlaug BA, Price MJ, Kawash R, Hummel SL, Cutlip DE, Leon MB, van Veldhuisen DJ, Rieth AJ, McKenzie S, Bugger H, Mazurek JA, Kapadia SR, Vanderheyden M, Ky B, Shah SJ (2024) Atrial shunt device effects on cardiac structure and function in heart failure with preserved ejection fraction: the REDUCE LAP-HF II randomized clinical trial. JAMA Cardiol 9(6):e240520. https://doi.org/10.1001/jamacardio.2024.0520

Article  Google Scholar 

Rodés-Cabau J, Bernier M, Amat-Santos IJ, Ben Gal T, Nombela-Franco L, García Del Blanco B, Kerner A, Bergeron S, Del Trigo M, Pibarot P, Shkurovich S, Eigler N, Abraham WT (2018) Interatrial shunting for heart failure: early and late results from the first-in-human experience with the V-wave system. JACC Cardiovasc Interv 11(22):2300–2310. https://doi.org/10.1016/j.jcin.2018.07.001

Article  PubMed