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Mortality from cerebrovascular diseases in China: Exploration of recent and future trends
Mortality from cerebrovascular diseases in China: Exploration of recent and future trends
Background: Cerebrovascular disease (CVD) ranks among the foremost factors responsible for mortal
Integrin β5 subunit regulates hyperglycemia-induced vascular endothelial cell apoptosis through FoxO1-mediated macroautophagy
Integrin β5 subunit regulates hyperglycemia-induced vascular endothelial cell apoptosis through FoxO1-mediated macroautophagy
Background: Hyperglycemia frequently induces apoptosis in endothelial cells and ultimately contri
Cluster analysis reveals a homogeneous subgroup of PCOS women with metabolic disturbance associated with adverse reproductive outcomes
Cluster analysis reveals a homogeneous subgroup of PCOS women with metabolic disturbance associated with adverse reproductive outcomes
Background: Polycystic ovarian syndrome (PCOS) is a heterogeneous and complex reproductive endocr
Advances in immunotherapy for biliary tract cancers
Advances in immunotherapy for biliary tract cancers
Biliary tract cancers (BTC), a heterogeneous disease with poor prognosis, including gallbladder canc
Dietary intake and serum levels of copper and zinc and risk of hepatocellular carcinoma: A matched case-control study
Dietary intake and serum levels of copper and zinc and risk of hepatocellular carcinoma: A matched case-control study
Background: Copper and zinc are involved in the development of multiple malignancies; yet, epidem
Prognostic value of calcium and phosphorus status in elderly heart disease patients with tricuspid regurgitation
Prognostic value of calcium and phosphorus status in elderly heart disease patients with tricuspid regurgitation
To the Editor: Tricuspid regurgitation (TR) associated with valve disease is a general medical issue with growing prevalen...
Bidirectional relationship between type 2 diabetes mellitus and coronary artery disease: Prospective cohort study and genetic analyses
Bidirectional relationship between type 2 diabetes mellitus and coronary artery disease: Prospective cohort study and genetic analyses
Background: While type 2 diabetes mellitus (T2DM) is considered a putative causal risk factor for
Gut virome: The next frontier in the treatment of necrotizing enterocolitis
Gut virome: The next frontier in the treatment of necrotizing enterocolitis
Necrotizing enterocolitis (NEC) is a devastating gastrointestinal disease over decades, which, however, remains the leadin...
Individualized brain mapping for navigated neuromodulation
Individualized brain mapping for navigated neuromodulation
The brain is a complex organ that requires precise mapping to understand its structure and function.
New progress of small-molecule drugs in the treatment of inflammatory bowel disease
New progress of small-molecule drugs in the treatment of inflammatory bowel disease
With the advent of small-molecule drugs, treatment of inflammatory bowel disease (IBD) has reached a new stage. In contras...
Associations of heavy metal mixtures with blood pressure among U.S. adults in NHANES 2017–2018 by four statistical models
Associations of heavy metal mixtures with blood pressure among U.S. adults in NHANES 2017–2018 by four statistical models
To the Editor: Hypertension is one of the leading risk factors for cardiovascular disease and affects approximately 30% of...
Clinical features and treatment outcomes of major depressive disorder with genital symptoms
Clinical features and treatment outcomes of major depressive disorder with genital symptoms
To the Editor: Major depressive disorder (MDD) is a mood disorder characterized by complex patterns of emotional, cognitiv...
Chinese expert consensus statement on the diagnosis and treatment of Hirschsprung disease
Chinese expert consensus statement on the diagnosis and treatment of Hirschsprung disease
Hirschsprung disease (HSCR) is a congenital anomaly of the intestine caused by the developmental absence of the enteric ne...
Pregnancy and the disease recurrence of patients previously treated for differentiated thyroid cancer: A systematic review and meta analysis
Pregnancy and the disease recurrence of patients previously treated for differentiated thyroid cancer: A systematic review and meta analysis
Background: Differentiated thyroid cancer (DTC) is commonly diagnosed in women of child-bearing a
Deciphering the implications of MAFLD and MASLD definitions in the NAFLD population: results from a single-center biopsy study
Deciphering the implications of MAFLD and MASLD definitions in the NAFLD population: results from a single-center biopsy study
To the Editor: The nomenclature for steatotic liver disease has been a topic of debate since 2020. The conventional expres...
A machine learning model for predicting acute kidney injury secondary to severe acute pancreatitis
A machine learning model for predicting acute kidney injury secondary to severe acute pancreatitis
To the Editor: Severe acute pancreatitis (SAP) is a common critical disease in gastroenterology, and 69.3% of patients hav...
Reporting quality evaluation of clinical practice guidelines for pulmonary nodules with the RIGHT checklist
Reporting quality evaluation of clinical practice guidelines for pulmonary nodules with the RIGHT checklist
To the Editor: Pulmonary nodules are defined as localized opacities of up to 30 mm in diameter, surrounded by pulmonary pa...
Recent advances and remaining challenges in lung cancer therapy
Recent advances and remaining challenges in lung cancer therapy
Lung cancer remains the most common cause of cancer death. Given the continued research into new dru
Application of artificial intelligence in diagnosis of pulmonary tuberculosis
Application of artificial intelligence in diagnosis of pulmonary tuberculosis
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. Although the diagnostic technology of pul...
Association of cardiopulmonary bypass with acute kidney injury in patients undergoing coronary artery bypass grafting: a retrospective cohort study
Association of cardiopulmonary bypass with acute kidney injury in patients undergoing coronary artery bypass grafting: a retrospective cohort study
To the Editor: Acute kidney injury (AKI) is a frequent complication of both cardiac and major non-cardiac surgeries. Cardi...
Metagenomic and targeted metabolomic analyses reveal distinct phenotypes of the gut microbiota in patients with colorectal cancer and type 2 diabetes mellitus
Metagenomic and targeted metabolomic analyses reveal distinct phenotypes of the gut microbiota in patients with colorectal cancer and type 2 diabetes mellitus
Background: Type 2 diabetes mellitus (T2DM) is an independent risk factor for colorectal cancer (
Clinical characteristics of flares in patients with rheumatoid arthritis after total hip and total knee arthroplasty
Clinical characteristics of flares in patients with rheumatoid arthritis after total hip and total knee arthroplasty
To the Editor: Introduction of conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) has been highly eff...
Jak inhibitors in vitiligo: a meta analysis
Jak inhibitors in vitiligo: a meta analysis
To the Editor: Vitiligo is an autoimmune disease characterized by depigmented patches of skin and is challenging to manage...
Clinical characteristics and risk factors for new-onset cervicogenic headache following elective craniotomy
Clinical characteristics and risk factors for new-onset cervicogenic headache following elective craniotomy
To the Editor: New-onset headache within a week after craniotomy is commonly recognized as acute post-craniotomy headache ...
Updates in psoriasis diagnosis and treatment status in China: results from the National Psoriasis Center Registry
Updates in psoriasis diagnosis and treatment status in China: results from the National Psoriasis Center Registry
To the Editor: Psoriasis is a common chronic immune-mediated systemic inflammatory disease[1] characterized by irritating ...
Systemic lupus erythematosus with diffuse alveolar hemorrhage
Systemic lupus erythematosus with diffuse alveolar hemorrhage
To the Editor: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the production of various auto...
Increased human neutrophil lipocalin and its clinical relevance in adult-onset Still's disease
Increased human neutrophil lipocalin and its clinical relevance in adult-onset Still's disease
Background: Human neutrophil lipocalin (HNL) has been used extensively to differentiate acute bac
Individualized red-cell transfusion strategy for non-cardiac surgery in adults: a randomized controlled trial
Individualized red-cell transfusion strategy for non-cardiac surgery in adults: a randomized controlled trial
Background: Red-cell transfusion is critical for surgery during the peri-operative period; howeve
Burden of multiple myeloma in China: an analysis of the Global Burden of Disease, Injuries, and Risk Factors Study 2019
Burden of multiple myeloma in China: an analysis of the Global Burden of Disease, Injuries, and Risk Factors Study 2019
Background: There is limited data to comprehensively evaluate the epidemiological characteristics
Menstrual irregularity, pregnancy outcomes, and birth outcomes in patients with systemic lupus erythematosus of childbearing age in China: a multicenter cross-sectional study
Menstrual irregularity, pregnancy outcomes, and birth outcomes in patients with systemic lupus erythematosus of childbearing age in China: a multicenter cross-sectional study
To the Editor: Systemic lupus erythematosus (SLE) is an autoimmune disease that tends to affect females of childbearing ag...
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