SCI Abstract

search
+
International Consortium to Classify Ageing-related Pathologies (ICCARP) senescence definitions: achieving international consensus
International Consortium to Classify Ageing-related Pathologies (ICCARP) senescence definitions: achieving international consensus
Normative ageingEvery individual ages uniquely. Whilst the literature has used terms such as ‘average’ and ‘typical’ agein...
The senolytic ABT-263 improves cognitive functions in middle-aged male, but not female, atherosclerotic LDLr;hApoB mice
The senolytic ABT-263 improves cognitive functions in middle-aged male, but not female, atherosclerotic LDLr;hApoB mice
Accumulation of cerebral senescent cells may compromise the continuum between vascular and neuronal function, leading to d...
Persisting blood–brain barrier disruption following cisplatin treatment in a mouse model of chemotherapy-associated cognitive impairment
Persisting blood–brain barrier disruption following cisplatin treatment in a mouse model of chemotherapy-associated cognitive impairment
Chemotherapy-related cognitive impairment, commonly referred to as “chemobrain,” significantly affects cancer ...
ChatGPT-estimated occupational complexity predicts cognitive outcomes and cortical thickness above and beyond socioeconomic status among older adults
ChatGPT-estimated occupational complexity predicts cognitive outcomes and cortical thickness above and beyond socioeconomic status among older adults
Many aging cohort studies have collected data on participants’ job titles, yet these job titles were seldom analyzed...
Awareness, knowledge, and motivations about lifespan, healthspan, and Healthy Longevity Medicine in the general population: the HEalthy LOngevity (HELO) conceptual framework
Awareness, knowledge, and motivations about lifespan, healthspan, and Healthy Longevity Medicine in the general population: the HEalthy LOngevity (HELO) conceptual framework
The global population is ageing and the gap between lifespan (total years lived) and healthspan (years lived free of disea...
SenSkin™: a human skin-specific cellular senescence gene set
SenSkin™: a human skin-specific cellular senescence gene set
Cellular senescence gene sets have been leveraged to overcome the inadequate sensitivity or specificity of single markers....
Improving care interactions (and training) in nursing homes with artificial intelligence
Improving care interactions (and training) in nursing homes with artificial intelligence
As the population continues to age, nursing homes will increasingly play a key role in caring for dependent individuals. T...
Decoding cognitive aging: how white matter tracts and demographics distinguish potential Super-Agers
Decoding cognitive aging: how white matter tracts and demographics distinguish potential Super-Agers
Most adults experience age-related cognitive decline. However, “Positive-Agers” exhibit superior cognition com...
Resistance exercise training in older men reduces ATF4-activated and senescence-associated mRNAs in skeletal muscle
Resistance exercise training in older men reduces ATF4-activated and senescence-associated mRNAs in skeletal muscle
Sarcopenia increases the risk of frailty, morbidity, and mortality in older adults. Resistance exercise training improves ...
Restoring neuropetide Y levels in the hypothalamus ameliorates premature aging phenotype in mice
Restoring neuropetide Y levels in the hypothalamus ameliorates premature aging phenotype in mice
The hypothalamus has been recognized as a regulator of whole-body aging. Neuropeptide Y (NPY), highly abundant in the cent...
Associations between shift work and biological age acceleration: A population-based study
Associations between shift work and biological age acceleration: A population-based study
This study aimed to examine the associations between shift work and biological age acceleration (BAA) and to explore poten...
Attention-dependent coupling with forebrain and brainstem neuromodulatory nuclei differs across the lifespan
Attention-dependent coupling with forebrain and brainstem neuromodulatory nuclei differs across the lifespan
Attentional states reflect the changing behavioral relevance of stimuli in one’s environment, having important conse...
Accelerated retinal ageing and multimorbidity in middle-aged and older adults
Accelerated retinal ageing and multimorbidity in middle-aged and older adults
The aim of this study is to investigate the association between retinal age gap and multimorbidity. Retinal age gap was ca...
Rationale and design of the Dog Aging Project precision cohort: a multi-omic resource for longitudinal research in geroscience
Rationale and design of the Dog Aging Project precision cohort: a multi-omic resource for longitudinal research in geroscience
A significant challenge in multi-omic geroscience research is the collection of high quality, fit-for-purpose biospecimens...
Construction and validation of a DNN-based biological age and its influencing factors in the China Kadoorie Biobank
Construction and validation of a DNN-based biological age and its influencing factors in the China Kadoorie Biobank
Biological age is an important measure of aging that reflects an individual’s physical health and is linked to vario...
Various diseases and conditions are strongly associated with the next-generation epigenetic aging clock CheekAge
Various diseases and conditions are strongly associated with the next-generation epigenetic aging clock CheekAge
Epigenetic aging clocks represent contemporary aging biomarkers that predict age using methylomic data. These models can b...
Correction to: Role of Toll-like receptor 2 and 4 signaling pathways on the inflammatory response to resistance training in elderly subjects
Correction to: Role of Toll-like receptor 2 and 4 signaling pathways on the inflammatory response to resistance training in elderly subjects
Correction to: GeroScience (2014) 36:9734The legend for Figure 2 has been corrected a...
The Semmelweis Study: a longitudinal occupational cohort study within the framework of the Semmelweis Caring University Model Program for supporting healthy aging
The Semmelweis Study: a longitudinal occupational cohort study within the framework of the Semmelweis Caring University Model Program for supporting healthy aging
The Semmelweis Study is a prospective occupational cohort study that seeks to enroll all employees of Semmelweis Universit...
Astaxanthin and meclizine extend lifespan in UM-HET3 male mice; fisetin, SG1002 (hydrogen sulfide donor), dimethyl fumarate, mycophenolic acid, and 4-phenylbutyrate do not significantly affect lifespan in either sex at the doses and schedules used
Astaxanthin and meclizine extend lifespan in UM-HET3 male mice; fisetin, SG1002 (hydrogen sulfide donor), dimethyl fumarate, mycophenolic acid, and 4-phenylbutyrate do not significantly affect lifespan in either sex at the doses and schedules used
In genetically heterogeneous (UM-HET3) mice produced by the CByB6F1 × C3D2F1 cross, the Nrf2 activator as...
Preventing spontaneous cerebral microhemorrhages in aging mice: a novel approach targeting cellular senescence with ABT263/navitoclax
Preventing spontaneous cerebral microhemorrhages in aging mice: a novel approach targeting cellular senescence with ABT263/navitoclax
Emerging evidence from both clinical and preclinical studies underscores the role of aging in potentiating the detrimental...
Correction to: Functional mobility and physical fitness are improved through a multicomponent training program in institutionalized older adults
Correction to: Functional mobility and physical fitness are improved through a multicomponent training program in institutionalized older adults
Cite this articleLópez‑López, S., Abuín‑Porras, V., Berlanga, L.A. et al. Correction to: Functional mobility and physical ...
The association of leukocyte telomere length with exceptional longevity among older women
The association of leukocyte telomere length with exceptional longevity among older women
The association of leukocyte telomere length (LTL) with survival to late life with intact mobility has not been adequately...
Immune cell composition varies by age, sex and exposure to social adversity in free-ranging Rhesus Macaques
Immune cell composition varies by age, sex and exposure to social adversity in free-ranging Rhesus Macaques
Increasing age is associated with dysregulated immune function and increased inflammation—patterns that are also obs...
The effect of glycine administration on the characteristics of physiological systems in human adults: A systematic review
The effect of glycine administration on the characteristics of physiological systems in human adults: A systematic review
Functional decline of physiological systems during ageing leads to age-related diseases. Dietary glycine increases healthy...
Comparative analysis of health status and health service utilization patterns among rural and urban elderly populations in Hungary: a study on the challenges of unhealthy aging
Comparative analysis of health status and health service utilization patterns among rural and urban elderly populations in Hungary: a study on the challenges of unhealthy aging
The demographic transition poses a significant challenge for health systems, especially in Central and Eastern European (C...
Age-specific difference in the temporal relationships between updated cardiovascular health construct and arterial stiffness in middle-aged and older adults
Age-specific difference in the temporal relationships between updated cardiovascular health construct and arterial stiffness in middle-aged and older adults
Previous studies have found that the association between modifiable risk factors and arterial stiffness varied with age. W...
Practice makes imperfect: stronger implicit interference with practice in individuals at high risk of developing Alzheimer’s disease
Practice makes imperfect: stronger implicit interference with practice in individuals at high risk of developing Alzheimer’s disease
Early screening to determine patient risk of developing Alzheimer’s will allow better interventions and planning but...
Autonomic nervous system imbalance during aging contributes to impair endogenous anti-inflammaging strategies
Autonomic nervous system imbalance during aging contributes to impair endogenous anti-inflammaging strategies
Inflammaging refers to the age-related low grade, sterile, chronic, systemic, and long-lasting subclinical, proinflammator...
OVCH1 Antisense RNA 1 is differentially expressed between non-frail and frail old adults
OVCH1 Antisense RNA 1 is differentially expressed between non-frail and frail old adults
While some old adults stay healthy and non-frail up to late in life, others experience multimorbidity and frailty often ac...
Systemic inflammatory and gut microbiota responses to fracture in young and middle-aged mice
Systemic inflammatory and gut microbiota responses to fracture in young and middle-aged mice
Age is a patient-specific factor that can significantly delay fracture healing and exacerbate systemic sequelae during con...
Load More
format_indent_increase