SCI Abstract

search
+
Evaluating Seqstant LiveGene Analysis in real-time assessment of metagenomic next-generation sequencing (mNGS) data from respiratory samples
Evaluating Seqstant LiveGene Analysis in real-time assessment of metagenomic next-generation sequencing (mNGS) data from respiratory samples
The detection of pathogens causing infections by conventional diagnostic methods can be challenging and next-generation se...
Endemic avian influenza landscape in Asia: sustained zoonotic risks
Endemic avian influenza landscape in Asia: sustained zoonotic risks
Avian influenza remains a persistent global health threat, with Asia at its epicentre due to dense poultry production, liv...
Is short-course antibiotic therapy as safe and effective as long-course therapy after surgery for complicated appendicitis? A systematic review and meta-analysis
Is short-course antibiotic therapy as safe and effective as long-course therapy after surgery for complicated appendicitis? A systematic review and meta-analysis
Short-course antibiotic (SCA) therapy after appendectomy for complicated appendicitis (CA) has gained increasing attention...
Otogenic meningitis in children
Otogenic meningitis in children
Otogenic meningitis is a rare but potentially life-threatening intracranial complication of otitis media (OM). Our aim was...
Profiling of circulating immune factors and host-derived extracellular vesicles in response to bacterial or malaria acute fever
Profiling of circulating immune factors and host-derived extracellular vesicles in response to bacterial or malaria acute fever
The misdiagnosis of acute febrile illness (AFI) aetiology is associated with antibiotic overuse and improper patient manag...
Efficacy and safety of colistin–doxycycline combination therapy in multi-drug resistance Gram-negative infections: a double-blind randomized controlled trial
Efficacy and safety of colistin–doxycycline combination therapy in multi-drug resistance Gram-negative infections: a double-blind randomized controlled trial
Multidrug-resistant (MDR) Klebsiella pneumoniae poses a critical treatment challenge. Colistin remains a last-resort antib...
Effectiveness, barriers, and facilitating factors of strategies for active delabeling of patients with penicillin allergy labels: a systematic review
Effectiveness, barriers, and facilitating factors of strategies for active delabeling of patients with penicillin allergy labels: a systematic review
Penicillin allergy is the most frequently reported allergy in hospitalized patients, although rarely confirmed. Given the ...
Severe destruction in vertebral osteomyelitis – risk factors and survival
Severe destruction in vertebral osteomyelitis – risk factors and survival
The treatment of vertebral osteomyelitis (VO) is multifaceted. In most cases, patients are treated conservatively. In the ...
Live microbials to boost Anti-SARS-CoV-2 immunity clinical trial (Live BASIC trial): a triple-blind randomized controlled trial
Live microbials to boost Anti-SARS-CoV-2 immunity clinical trial (Live BASIC trial): a triple-blind randomized controlled trial
With waning immunity and vaccine hesitancy, the COVID-19 pandemic continues to pose risks. A live microbial consortium (OL...
Cerebrospinal fluid findings and their temporal pattern in patients with different clinical presentations of tick-borne encephalitis; a cohort study
Cerebrospinal fluid findings and their temporal pattern in patients with different clinical presentations of tick-borne encephalitis; a cohort study
There is a lack of systematic data on cerebrospinal fluid (CSF) findings in the different clinical manifestations of tick-...
Pathogen identification and outcome in adult patients with community-acquired pneumonia in Switzerland: findings from the Swiss CAPNETZ cohort study
Pathogen identification and outcome in adult patients with community-acquired pneumonia in Switzerland: findings from the Swiss CAPNETZ cohort study
Community-acquired pneumonia (CAP) causes significant morbidity and mortality, but Swiss data are limited. We analyzed the...
Melioidosis imported to Northern Germany: a case report series
Melioidosis imported to Northern Germany: a case report series
Melioidosis is a serious infection caused by Burkholderia pseudomallei, a bacterium found in soil, water, and plants in tr...
Chronic carriers and multidrug resistance in typhoid fever: pathogenesis, challenges, and integrated control strategies
Chronic carriers and multidrug resistance in typhoid fever: pathogenesis, challenges, and integrated control strategies
Typhoid fever, a systemic disease caused by Salmonella enterica serovar Typhi (S. Typhi), remains a major global health pr...
Think sepsis, write sepsis, code sepsis – patient characteristics associated with sepsis (under-)coding in administrative health data
Think sepsis, write sepsis, code sepsis – patient characteristics associated with sepsis (under-)coding in administrative health data
Sepsis is a leading cause of morbidity and mortality, yet its documentation and coding in administrative health data remai...
Epidemiological profile of causative agents in nosocomial pneumonia: a four-year multicenter surveillance study from Georgia (2020–2023)
Epidemiological profile of causative agents in nosocomial pneumonia: a four-year multicenter surveillance study from Georgia (2020–2023)
Nosocomial pneumonia (NP), including hospital-acquired (HAP) and ventilator-associated pneumonia (VAP), remains a leading ...
Complicated ulceroglandular tularemia
Complicated ulceroglandular tularemia
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
Definitional ambiguity and the dual threat of Hypervirulent infections: a systematic review and meta-analysis
Definitional ambiguity and the dual threat of Hypervirulent infections: a systematic review and meta-analysis
Hypervirulent Klebsiella pneumoniae (HvKp) causes severe invasive infections, but the lack of a standardized definition co...
Effectiveness of antibiotic prophylaxis for ventilator-associated pneumonia in acute brain injury: a systematic review and meta-analysis
Effectiveness of antibiotic prophylaxis for ventilator-associated pneumonia in acute brain injury: a systematic review and meta-analysis
Ventilator-associated pneumonia (VAP) affects 30–50% of mechanically ventilated patients with acute brain injury (AB...
Identifying patients at high risk for antibiotic treatment following hospital admission: a predictive score to improve antimicrobial stewardship measures
Identifying patients at high risk for antibiotic treatment following hospital admission: a predictive score to improve antimicrobial stewardship measures
Identifying patients for clinical studies evaluating strategies to reduce unnecessary antibiotic usage in hospitals is cha...
Efficacy of tocilizumab for hospitalized patients with COVID-19 pneumonia and high IL-6 levels: A randomized controlled trial
Efficacy of tocilizumab for hospitalized patients with COVID-19 pneumonia and high IL-6 levels: A randomized controlled trial
The objective of this clinical trial is to evaluate the efficacy and safety of IL-6 driven personalized treatment strategy...
Piperacillin/tazobactam versus carbapenems for 30-day mortality in patients with ESBL-producing Enterobacterales bloodstream infections: a retrospective, multicenter, non-inferiority, cohort study
Piperacillin/tazobactam versus carbapenems for 30-day mortality in patients with ESBL-producing Enterobacterales bloodstream infections: a retrospective, multicenter, non-inferiority, cohort study
Antimicrobial resistance increases with the use of broad-spectrum antibiotics. Studies evaluating antibiotic stewardship a...
Towards shortening the duration of antibiotic therapy for Lyme borreliosis: a systematic review and meta-analysis
Towards shortening the duration of antibiotic therapy for Lyme borreliosis: a systematic review and meta-analysis
Systematic review and meta-analysis on shortening antibiotic therapy for Lyme borreliosis (LB) patients. Data sources: Med...
Molecular and ecological determinants of mammalian adaptability in avian influenza virus
Molecular and ecological determinants of mammalian adaptability in avian influenza virus
The avian influenza virus (AIV) primarily affects birds and poses an increasing concern due to its growing adaptability to...
When oral health affects overall health: biofilms, dental infections, and emerging antimicrobial strategies
When oral health affects overall health: biofilms, dental infections, and emerging antimicrobial strategies
Dental health is a crucial component of overall health, yet it is frequently overlooked in discussions about well-being. T...
A simple clinical tool for effective screening of haemophagocytic lymphohistiocytosis in dengue
A simple clinical tool for effective screening of haemophagocytic lymphohistiocytosis in dengue
Haemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening disorder. Dengue fever is a common trigger for HLH i...
Clinical impact of bronchoalveolar lavage fluid metagenomic next-generation sequencing in immunocompromised patients with severe community-acquired pneumonia in ICU: a multicenter retrospective study
Clinical impact of bronchoalveolar lavage fluid metagenomic next-generation sequencing in immunocompromised patients with severe community-acquired pneumonia in ICU: a multicenter retrospective study
An increasing number of critically ill patients are immunocompromised. These patients are at high risk of intensive care u...
Healthcare professionals challenged by 14 distinct carbapenemase-producing micro-organisms in a war-injured Ukrainian patient
Healthcare professionals challenged by 14 distinct carbapenemase-producing micro-organisms in a war-injured Ukrainian patient
The Russia-Ukraine war lead to evacuation of patients across Europe. We present an unprecedented case of a severely injure...
Acral necrosis in a 62-year-old female after travelling to Equatorial Guinea
Acral necrosis in a 62-year-old female after travelling to Equatorial Guinea
A previously healthy 62-year-old woman presented to our clinic after a two-day stay in Equatorial Guinea. Her symptoms inc...
Model-informed identification of optimised dosing strategies for meropenem in critically ill patients receiving SLEDD: an observational study
Model-informed identification of optimised dosing strategies for meropenem in critically ill patients receiving SLEDD: an observational study
An increasing number of critically ill patients receive slow extended daily dialysis (SLEDD) due to their pathophysiology ...
Raising awareness of : a neglected cause of skin disease
Raising awareness of : a neglected cause of skin disease
Demodex mites are among the most prevalent human parasites. While commonly found on healthy individuals, an overpopulation...
Load More
format_indent_increase