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SLIC-Occ: functional segmentation of occupancy images improves precision of EC50 images
SLIC-Occ: functional segmentation of occupancy images improves precision of EC50 images
Drug occupancy studies with positron emission tomography imaging are used routinely in early phase drug development trials...
SAFIR-I: first NEMA NU 4-2008-based performance characterization
SAFIR-I: first NEMA NU 4-2008-based performance characterization
Small Animal Fast Insert for MRI detector I (SAFIR-I) is a novel Positron Emission Tomography insert for a $$7\,\hbox $$ B...
90Y SPECT scatter estimation and voxel dosimetry in radioembolization using a unified deep learning framework
90Y SPECT scatter estimation and voxel dosimetry in radioembolization using a unified deep learning framework
90Y SPECT-based dosimetry following radioembolization (RE) in liver malignancies is challenging due to the inherent scatte...
Clinical application of a population-based input function (PBIF) for a shortened dynamic whole-body FDG-PET/CT protocol in patients with metastatic melanoma treated by immunotherapy
Clinical application of a population-based input function (PBIF) for a shortened dynamic whole-body FDG-PET/CT protocol in patients with metastatic melanoma treated by immunotherapy
The aim was to investigate the feasibility of a shortened dynamic whole-body (dWB) FDG-PET/CT protocol and Patlak imaging ...
Accurate image derived input function in [18F]SynVesT-1 mouse studies using isoflurane and ketamine/xylazine anesthesia
Accurate image derived input function in [18F]SynVesT-1 mouse studies using isoflurane and ketamine/xylazine anesthesia
Kinetic modeling in positron emission tomography (PET) requires measurement of the tracer plasma activity in the absence o...
16-channel SiPM high-frequency readout with time-over-threshold discrimination for ultrafast time-of-flight applications
16-channel SiPM high-frequency readout with time-over-threshold discrimination for ultrafast time-of-flight applications
Over the past five years, ultrafast high-frequency (HF) readout concepts have advanced the timing performance of ...
Optimisation of the air fraction correction for lung PET/CT: addressing resolution mismatch
Optimisation of the air fraction correction for lung PET/CT: addressing resolution mismatch
Increased pulmonary $$^$$ F-FDG metabolism in patients with idiopathic pulmonary fibrosis, and other forms of diffuse pare...
A simulation study of the system characteristics for a long axial FOV PET design based on monolithic BGO flat panels compared with a pixelated LSO cylindrical design
A simulation study of the system characteristics for a long axial FOV PET design based on monolithic BGO flat panels compared with a pixelated LSO cylindrical design
Although a new generation of tomographs with a longer axial field-of-view called total-body PET have been developed, they ...
Correction: Precision dosimetry in yttrium-90 radioembolization through CT imaging of radiopaque microspheres in a rabbit liver model
Correction: Precision dosimetry in yttrium-90 radioembolization through CT imaging of radiopaque microspheres in a rabbit liver model
In this article [1], James J. Karnia at affiliation “Department of Veterinary Medicine and Surgery, University of Missouri...
Parametric and non-parametric Poisson regression for modelling of the arterial input function in positron emission tomography
Parametric and non-parametric Poisson regression for modelling of the arterial input function in positron emission tomography
Full quantification of Positron Emission Tomography (PET) requires an arterial input function (AIF) for measurement of cer...
On the use of solid 133Ba sources as surrogate for liquid 131I in SPECT/CT calibration: a European multi-centre evaluation
On the use of solid 133Ba sources as surrogate for liquid 131I in SPECT/CT calibration: a European multi-centre evaluation
Commissioning, calibration, and quality control procedures for nuclear medicine imaging systems are typically performed us...
Harmonization of brain PET images in multi-center PET studies using Hoffman phantom scan
Harmonization of brain PET images in multi-center PET studies using Hoffman phantom scan
Image harmonization has been proposed to minimize heterogeneity in brain PET scans acquired in multi-center studies. Howev...
Replacing Lu-177 with Tb-161 in DOTA-TATE and PSMA-617 therapy: potential dosimetric implications for activity selection
Replacing Lu-177 with Tb-161 in DOTA-TATE and PSMA-617 therapy: potential dosimetric implications for activity selection
To explore the dosimetric effect of substituting Lu-177 with Tb-161 in targeted radionuclide therapy (TRT) using the regis...
An automatic pipeline for PET/MRI attenuation correction validation in the brain
An automatic pipeline for PET/MRI attenuation correction validation in the brain
Challenges in PET/MRI quantitative accuracy for neurological uses arise from PET attenuation correction accuracy. We propo...
Radiation exposure assessment of nuclear medicine staff administering [177Lu]Lu-DOTA-TATE with active and passive dosimetry
Radiation exposure assessment of nuclear medicine staff administering [177Lu]Lu-DOTA-TATE with active and passive dosimetry
The use of lutetium-177 (177Lu)-based radiopharmaceuticals in peptide receptor nuclear therapy is increasing, but so is th...
Combining deep learning with a kinetic model to predict dynamic PET images and generate parametric images
Combining deep learning with a kinetic model to predict dynamic PET images and generate parametric images
Dynamic positron emission tomography (PET) images are useful in clinical practice because they can be used to calculate th...
Ultra-low-dose CT for attenuation correction: dose savings and effect on PET quantification for protocols with and without tin filter
Ultra-low-dose CT for attenuation correction: dose savings and effect on PET quantification for protocols with and without tin filter
Ultra-low-dose (ULD) computed tomography (CT) scans should be used when CT is performed only for attenuation correction (A...
Optimization of Q.Clear reconstruction for dynamic 18F PET imaging
Optimization of Q.Clear reconstruction for dynamic 18F PET imaging
Q.Clear, a Bayesian penalized likelihood reconstruction algorithm, has shown high potential in improving quantitation accu...
The effects of various penalty parameter values in Q.Clear algorithm for rectal cancer detection on 18F-FDG images using a BGO-based PET/CT scanner: a phantom and clinical study
The effects of various penalty parameter values in Q.Clear algorithm for rectal cancer detection on 18F-FDG images using a BGO-based PET/CT scanner: a phantom and clinical study
The Q.Clear algorithm is a fully convergent iterative image reconstruction technique. We hypothesize that different PET/CT...
Quantitative 177Lu SPECT/CT imaging for personalized dosimetry using a ring-shaped CZT-based camera
Quantitative 177Lu SPECT/CT imaging for personalized dosimetry using a ring-shaped CZT-based camera
Dosimetry after radiopharmaceutical therapy with 177Lu (177Lu-RPT) relies on quantitative SPECT/CT imaging, for which suit...
PET imaging and quantification of small animals using a clinical SiPM-based camera
PET imaging and quantification of small animals using a clinical SiPM-based camera
Small-animal PET imaging is an important tool in preclinical oncology. This study evaluated the ability of a clinical SiPM...
Comparative studies of the sensitivities of sparse and full geometries of Total-Body PET scanners built from crystals and plastic scintillators
Comparative studies of the sensitivities of sparse and full geometries of Total-Body PET scanners built from crystals and plastic scintillators
Alongside the benefits of Total-Body imaging modalities, such as higher sensitivity, single-bed position, low dose imaging...
Quantitative validation of Monte Carlo SPECT simulation: application to a Mediso AnyScan GATE simulation
Quantitative validation of Monte Carlo SPECT simulation: application to a Mediso AnyScan GATE simulation
Monte Carlo (MC) simulations are used in nuclear medicine imaging as they provide unparalleled insight into processes that...
Abstracts of the Total Body PET 2022 conference
Abstracts of the Total Body PET 2022 conference
Karla J. Suchacki 1*, Rucha Ronghe1, David Dye2, Catriona Wimberley...
Performance study of a 360° CZT camera for monitoring 177Lu-PSMA treatment
Performance study of a 360° CZT camera for monitoring 177Lu-PSMA treatment
The aim of this study was to investigate the quantification performance of a 360° CZT camera for 177Lu-based treatmen...
Guided block matching and 4-D transform domain filter projection denoising method for dynamic PET image reconstruction
Guided block matching and 4-D transform domain filter projection denoising method for dynamic PET image reconstruction
Dynamic PET is an essential tool in oncology due to its ability to visualize and quantify radiotracer uptake, which has th...
Clinical validation of an AI-based automatic quantification tool for lung lobes in SPECT/CT
Clinical validation of an AI-based automatic quantification tool for lung lobes in SPECT/CT
Lung lobar ventilation and perfusion (V/Q) quantification is generally obtained by generating planar scintigraphy images a...
A proper protocol for routine 18F-FDG uEXPLORER total-body PET/CT scans
A proper protocol for routine 18F-FDG uEXPLORER total-body PET/CT scans
Conventional clinical PET scanners typically have an axial field of view (AFOV) of 15–30 cm, resulting in l...
Estimation of relative biological effectiveness of 225Ac compared to 177Lu during [225Ac]Ac-PSMA and [177Lu]Lu-PSMA radiopharmaceutical therapy using TOPAS/TOPAS-nBio/MEDRAS
Estimation of relative biological effectiveness of 225Ac compared to 177Lu during [225Ac]Ac-PSMA and [177Lu]Lu-PSMA radiopharmaceutical therapy using TOPAS/TOPAS-nBio/MEDRAS
Over recent years, [225Ac]Ac-PSMA and [177Lu]Lu-PSMA radiopharmaceutical therapy have evolved as a promising treatment opt...
A review of PET attenuation correction methods for PET-MR
A review of PET attenuation correction methods for PET-MR
Despite being thirteen years since the installation of the first PET-MR system, the scanners constitute a very small propo...
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