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Thrombospondin-1 induces CD8+ T cell exhaustion and immune suppression within the tumor microenvironment of ovarian cancer
Thrombospondin-1 induces CD8+ T cell exhaustion and immune suppression within the tumor microenvironment of ovarian cancer
Ovarian cancer (OC) progression is heavily influenced by the tumor microenvironment (TME), where immune suppression plays ...
Malignant ascites in ovarian cancer is compatible with long-term (10 year) survival with associations to clinicopathological features
Malignant ascites in ovarian cancer is compatible with long-term (10 year) survival with associations to clinicopathological features
Ovarian cancer can present with malignant ascites at initial diagnosis or disease recurrence. Although indicative of advan...
Effects of melatonin in polycystic ovary syndrome: is there Hippo pathway crosstalk?
Effects of melatonin in polycystic ovary syndrome: is there Hippo pathway crosstalk?
Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder among reproductive women, characterized by hyperandroge...
Immunotherapy in young adults with mature cystic ovarian Teratoma-Derived squamous cell carcinoma: a case series
Immunotherapy in young adults with mature cystic ovarian Teratoma-Derived squamous cell carcinoma: a case series
Mature cystic teratomas (MCTs), also known as dermoid cysts, are common benign germ cell tumors. These predominantly benig...
LncRNA NEAT1 participates in diminished ovarian reserve by affecting granulosa cell apoptosis and estradiol synthesis via the miR-204-5p/ESR1 axis
LncRNA NEAT1 participates in diminished ovarian reserve by affecting granulosa cell apoptosis and estradiol synthesis via the miR-204-5p/ESR1 axis
Long non-coding RNAs (lncRNAs) affect the biological functions of granulosa cells (GCs) through multiple mechanisms, inclu...
Retraction Note: H3K27ac-induced lncRNA PAXIP1-AS1 promotes cell proliferation, migration, EMT and apoptosis in ovarian cancer by targeting miR-6744-5p/PCBP2 axis
Retraction Note: H3K27ac-induced lncRNA PAXIP1-AS1 promotes cell proliferation, migration, EMT and apoptosis in ovarian cancer by targeting miR-6744-5p/PCBP2 axis
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
MiR-134-3p targets HMOX1 to inhibit ferroptosis in granulosa cells of sheep follicles
MiR-134-3p targets HMOX1 to inhibit ferroptosis in granulosa cells of sheep follicles
The intricate interplay of gene expression within ovarian granulosa cells (GCs) is not fully understood. This study aimed ...
In-vitro generation of follicle-like structures from human germ cell-like cells derived from theca stem cell combined with ovarian somatic cells
In-vitro generation of follicle-like structures from human germ cell-like cells derived from theca stem cell combined with ovarian somatic cells
The objective of this study was to induce the differentiation of human theca stem cells (hTSCs) into germ cell-like cells ...
Do we overlook predictive factors in Poseidon 1 patients? A retrospective analysis co-evaluating antral follicle counts & diameters
Do we overlook predictive factors in Poseidon 1 patients? A retrospective analysis co-evaluating antral follicle counts & diameters
An unexpected impaired ovarian response pertains to an insufficient reaction to controlled ovarian hyperstimulation. This ...
Exosomal biomarkers in the differential diagnosis of ovarian tumors: the emerging roles of CA125, HE4, and C5a
Exosomal biomarkers in the differential diagnosis of ovarian tumors: the emerging roles of CA125, HE4, and C5a
Investigating the utility of serum exosomal markers CA125, HE4, and C5a, both individually and in combination, for disting...
The pregnancy and oncology outcome of fertility-sparing management for synchronous primary neoplasm of endometrium and ovary
The pregnancy and oncology outcome of fertility-sparing management for synchronous primary neoplasm of endometrium and ovary
To investigate the efficacy of fertility-preserving treatment for young women with synchronous primary neoplasm of endomet...
Characterization of MicroRNA expression profiles in the ovarian tissue of goats during the sexual maturity period
Characterization of MicroRNA expression profiles in the ovarian tissue of goats during the sexual maturity period
The ovary is an important reproductive organ in mammals, and its development directly affects the sexual maturity and repr...
Proteomic analysis of exosomes secreted during the epithelial-mesenchymal transition and potential biomarkers of mesenchymal high-grade serous ovarian carcinoma
Proteomic analysis of exosomes secreted during the epithelial-mesenchymal transition and potential biomarkers of mesenchymal high-grade serous ovarian carcinoma
The epithelial-mesenchymal transition (EMT) promotes cell signaling and morphology alterations, contributing to cancer pro...
Adipose-derived exosomal miR-421 targets CBX7 and promotes metastatic potential in ovarian cancer cells
Adipose-derived exosomal miR-421 targets CBX7 and promotes metastatic potential in ovarian cancer cells
Chromobox protein homolog 7 (CBX7), a member of the Polycomb repressor complex, is a potent epigenetic regulator and gene ...
BRCA1 and BRCA2 deficient tumour models generate distinct ovarian tumour microenvironments and differential responses to therapy
BRCA1 and BRCA2 deficient tumour models generate distinct ovarian tumour microenvironments and differential responses to therapy
Clinical trials are currently exploring combinations of PARP inhibitors and immunotherapies for the treatment of ovarian c...
The prolactin receptor gene (PRLR) is linked and associated with the risk of polycystic ovarian syndrome
The prolactin receptor gene (PRLR) is linked and associated with the risk of polycystic ovarian syndrome
The prolactin receptor gene (PRLR) may contribute to polycystic ovarian syndrome (PCOS) since it plays important roles in ...
Dose inhibin B or anti-Müllerian hormone relate to precocious puberty in girls? result of a systematic review and meta-analysis
Dose inhibin B or anti-Müllerian hormone relate to precocious puberty in girls? result of a systematic review and meta-analysis
Existing studies have investigated the relationship between the levels of serum inhibin B (INHB), anti-müllerian horm...
Progress of the application clinical prediction model in polycystic ovary syndrome
Progress of the application clinical prediction model in polycystic ovary syndrome
Clinical prediction models play an important role in the field of medicine. These can help predict the probability of an i...
Novel variants in TUBB8 gene cause multiple phenotypic abnormalities in human oocytes and early embryos
Novel variants in TUBB8 gene cause multiple phenotypic abnormalities in human oocytes and early embryos
The genotype-phenotype relationships between TUBB8 variants and female infertility are difficult to clearly define due to ...
IFN-γ in ovarian tumor microenvironment upregulates HLA-E expression and predicts a poor prognosis
IFN-γ in ovarian tumor microenvironment upregulates HLA-E expression and predicts a poor prognosis
Inflammation and immunity are two main characteristics of tumor microenvironment (TME). Interferon-gamma (IFN-γ) is g...
The effect of calorie-restriction along with thylakoid membranes of spinach on the gut-brain Axis Pathway and oxidative stress biomarkers in obese women with polycystic ovary syndrome: a Randomized, Double-blind, placebo-controlled clinical trial
The effect of calorie-restriction along with thylakoid membranes of spinach on the gut-brain Axis Pathway and oxidative stress biomarkers in obese women with polycystic ovary syndrome: a Randomized, Double-blind, placebo-controlled clinical trial
Women with polycystic ovary syndrome (PCOS) have higher intestinal mucosal permeability, leading to the lipopolysaccharide...
The long non-coding RNA NEAT1 promotes the progression of human ovarian cancer through targeting miR-214-3p and regulating angiogenesis
The long non-coding RNA NEAT1 promotes the progression of human ovarian cancer through targeting miR-214-3p and regulating angiogenesis
Angiogenesis and metastasis contributes substantially to the poor outcome of patients with ovarian cancer. We aimed to exp...
Correction: Effects and mechanisms of mUCMSCs on ovarian structure and function in naturally ageing C57 mice
Correction: Effects and mechanisms of mUCMSCs on ovarian structure and function in naturally ageing C57 mice
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Prerequisites to improve surgical cytoreduction in FIGO stage III/IV epithelial ovarian cancer and subsequent clinical ramifications
Prerequisites to improve surgical cytoreduction in FIGO stage III/IV epithelial ovarian cancer and subsequent clinical ramifications
No residual disease (CC 0) following cytoreductive surgery is pivotal for the prognosis of women with advanced stage epith...
Causal pathways linking polycystic ovary syndrome to distinct breast cancer subtypes through mediator factors: a multivariable mendelian randomization analysis
Causal pathways linking polycystic ovary syndrome to distinct breast cancer subtypes through mediator factors: a multivariable mendelian randomization analysis
Polycystic ovary syndrome (PCOS) is an endocrine disorder characterized by ovarian cysts, high androgen levels, and irregu...
Investigation of androgen receptor CAG repeats length in polycystic ovary syndrome diagnosed using the new international evidence-based guideline
Investigation of androgen receptor CAG repeats length in polycystic ovary syndrome diagnosed using the new international evidence-based guideline
To study whether CAG repeat polymorphism of androgen receptor (AR) contributes to the risk of polycystic ovarian morpholog...
Baicalein improves the chemoresistance of ovarian cancer through regulation of CirSLC7A6
Baicalein improves the chemoresistance of ovarian cancer through regulation of CirSLC7A6
The present study aimed to investigate whether baicalein improves the sensitivity of resistant ovarian cancer cells to cis...
Three-dimensional architecture of granulosa cell derived from oocyte cumulus complex, revealed by FIB-SEM
Three-dimensional architecture of granulosa cell derived from oocyte cumulus complex, revealed by FIB-SEM
The oocyte cumulus complex is mainly composed of an oocyte, the perivitelline space, zona pellucida and numerous granulosa...
Oxidative stress and inflammatory markers in ovarian follicular fluid of women with diminished ovarian reserve during in vitro fertilization
Oxidative stress and inflammatory markers in ovarian follicular fluid of women with diminished ovarian reserve during in vitro fertilization
Follicular microenvironment has been proposed as an important factor for oocyte grown and maturation. We sought to evaluat...
Potential factors result in diminished ovarian reserve: a comprehensive review
Potential factors result in diminished ovarian reserve: a comprehensive review
The ovarian reserve is defined as the quantity of oocytes stored in the ovary or the number of oocytes that can be recruit...
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