Barry V, Winquist A, Steenland K. Perfluorooctanoic acid (PFOA) exposures and incident cancers among adults living near a chemical plant. Environ Health Perspect. 2013;121(11–12):1313–8.

Google Scholar 

Burger M, Catto JW, Dalbagni G, Grossman HB, Herr H, Karakiewicz P, et al. Epidemiology and risk factors of urothelial bladder cancer. Eur Urol. 2013;63(2):234–41.

Google Scholar 

Classen S, Olland S, Berger JM. Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187. Proc Natl Acad Sci U S A. 2003;100(19):10629–34.

Google Scholar 

Consonni D, Fustinoni S. Biochemical and haematological effects of serum PFOA, ADV and cC(6)O(4) in workers of a chemical company producing fluoropolymers, Italy, 2013–2022. Int J Hyg Environ Health. 2024;262:114440.

Google Scholar 

Cotruvo JA, Goldhaber SB, Cohen AJB. EPA’s unprecedented interim drinking water health advisories for PFOA and PFOS. Ground Water. 2023;61(3):301–3.

Google Scholar 

Cumberbatch MG, Rota M, Catto JW, La Vecchia C. The role of tobacco smoke in bladder and kidney carcinogenesis: a comparison of exposures and meta-analysis of incidence and mortality risks. Eur Urol. 2016;70(3):458–66.

Google Scholar 

Dai Y, Shaikho EM, Perez J, Wilson CA, Liu LY, White MR, et al. BCL2L1 is associated with gamma-globin gene expression. Blood Adv. 2019;3(20):2995–3001.

Google Scholar 

Dewitt JC, Copeland CB, Strynar MJ, Luebke RW. Perfluorooctanoic acid-induced immunomodulation in adult C57BL/6J or C57BL/6N female mice. Environ Health Perspect. 2008;116(5):644–50.

Google Scholar 

Dudderidge TJ, Stoeber K, Loddo M, Atkinson G, Fanshawe T, Griffiths DF, et al. Mcm2, Geminin, and KI67 define proliferative state and are prognostic markers in renal cell carcinoma. Clin Cancer Res. 2005;11(7):2510–7.

Google Scholar 

Filgo AJ, Quist EM, Hoenerhoff MJ, Brix AE, Kissling GE, Fenton SE. Perfluorooctanoic acid (PFOA)-induced liver lesions in two strains of mice following developmental exposures: PPARalpha is not required. Toxicol Pathol. 2015;43(4):558–68.

Google Scholar 

Ghervan L, Zaharie A, Ene B, Elec FI. Small-cell carcinoma of the urinary bladder: where do we stand? Med Pharm Rep. 2017;90(1):13–7.

Google Scholar 

Gontero P, Birtle A, Capoun O, Comperat E, Dominguez-Escrig JL, Liedberg F, et al. European Association of Urology guidelines on non-muscle-invasive bladder cancer (TaT1 and carcinoma in situ)-a summary of the 2024 guidelines update. Eur Urol. 2024;86(6):531–49.

Google Scholar 

Grandjean P, Clapp R. Perfluorinated alkyl substances: emerging insights into health risks. New Solut. 2015;25(2):147–63.

Google Scholar 

Grandjean P, Andersen EW, Budtz-Jorgensen E, Nielsen F, Molbak K, Weihe P, et al. Serum vaccine antibody concentrations in children exposed to perfluorinated compounds. JAMA. 2012;307(4):391–7.

Google Scholar 

Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144(5):646–74.

Google Scholar 

Jacobs BL, Lee CT, Montie JE. Bladder cancer in 2010: how far have we come? CA Cancer J Clin. 2010;60(4):244–72.

Google Scholar 

Jian JM, Guo Y, Zeng L, Liang-Ying L, Lu X, Wang F, et al. Global distribution of perfluorochemicals (PFCs) in potential human exposure source-a review. Environ Int. 2017;108:51–62.

Google Scholar 

Kanetani K, Nakamura K, Harada KH, Akihisa H, Oshima T, Ogata H, et al. High serum perfluorooctanoic acid (PFOA) concentrations and interstitial lung disease in former and current workers in a fluorochemical company. Ind Health. 2025.

Google Scholar 

Karakiewicz PI, Benayoun S, Zippe C, Ludecke G, Boman H, Sanchez-Carbayo M, et al. Institutional variability in the accuracy of urinary cytology for predicting recurrence of transitional cell carcinoma of the bladder. BJU Int. 2006;97(5):997–1001.

Google Scholar 

Lau C, Anitole K, Hodes C, Lai D, Pfahles-Hutchens A, Seed J. Perfluoroalkyl acids: a review of monitoring and toxicological findings. Toxicol Sci. 2007;99(2):366–94.

Google Scholar 

Letasiova S, Medve'ova A, Sovcikova A, Dusinska M, Volkovova K, Mosoiu C, Bartonova A: Bladder cancer, a review of the environmental risk factors. Environ Health 2012, 11 Suppl 1(Suppl 1):S11

Lopez-Espinosa MJ, Mondal D, Armstrong B, Bloom MS, Fletcher T. Thyroid function and perfluoroalkyl acids in children living near a chemical plant. Environ Health Perspect. 2012;120(7):1036–41.

Google Scholar 

Malumbres M, Barbacid M. Cell cycle, CDKs and cancer: a changing paradigm. Nat Rev Cancer. 2009;9(3):153–66.

Google Scholar 

Musgrove EA, Caldon CE, Barraclough J, Stone A, Sutherland RL. Cyclin D as a therapeutic target in cancer. Nat Rev Cancer. 2011;11(8):558–72.

Google Scholar 

Nitiss JL. Targeting DNA topoisomerase II in cancer chemotherapy. Nat Rev Cancer. 2009;9(5):338–50.

Google Scholar 

Nuijens ST, van Hoogstraten LMC, Terpstra NB, Beeren I, Vrieling A, Wijnen EM, Meijer RP, Kiemeney LA, Witjes JA, Aben KKH: The impact of treatment for muscle-invasive bladder cancer on health-related quality of life. BJU Int 2025

Pitter G, Da Re F, Canova C, Barbieri G, Zare Jeddi M, Dapra F, et al. Serum Levels of Perfluoroalkyl Substances (PFAS) in Adolescents and Young Adults Exposed to Contaminated Drinking Water in the Veneto Region, Italy: A Cross-Sectional Study Based on a Health Surveillance Program. Environ Health Perspect. 2020;128(2):27007.

Google Scholar 

Post GB, Cohn PD, Cooper KR. Perfluorooctanoic acid (PFOA), an emerging drinking water contaminant: a critical review of recent literature. Environ Res. 2012;116:93–117.

Google Scholar 

Qu K, Wang Z, Fan H, Li J, Liu J, Li P, et al. MCM7 promotes cancer progression through cyclin D1-dependent signaling and serves as a prognostic marker for patients with hepatocellular carcinoma. Cell Death Dis. 2017;8(2):e2603.

Google Scholar 

Richters A, Aben KKH, Kiemeney L. The global burden of urinary bladder cancer: an update. World J Urol. 2020;38(8):1895–904.

Google Scholar 

Schepers H, Wierenga AT, Eggen BJ, Vellenga E. Oncogenic Ras blocks transforming growth factor-beta-induced cell-cycle arrest by degradation of p27 through a MEK/Erk/SKP2-dependent pathway. Exp Hematol. 2005;33(7):747–57.

Google Scholar 

Siegel RL, Giaquinto AN, Jemal A. Cancer statistics, 2024. CA Cancer J Clin. 2024;74(1):12–49.

Google Scholar 

Steenland K, Woskie S. Cohort mortality study of workers exposed to perfluorooctanoic acid. Am J Epidemiol. 2012;176(10):909–17.

Google Scholar 

Steenland K, Fletcher T, Savitz DA. Epidemiologic evidence on the health effects of perfluorooctanoic acid (PFOA). Environ Health Perspect. 2010;118(8):1100–8.

Google Scholar 

Steenland K, Zhao L, Winquist A, Parks C. Ulcerative colitis and perfluorooctanoic acid (PFOA) in a highly exposed population of community residents and workers in the mid-Ohio valley. Environ Health Perspect. 2013;121(8):900–5.

Google Scholar 

Steenland K, Zhao L, Winquist A. A cohort incidence study of workers exposed to perfluorooctanoic acid (PFOA). Occup Environ Med. 2015;72(5):373–80.

Google Scholar 

Subiela JD, Guerrero-Ramos F, Rodriguez-Faba O, Aumatell J, Gajate P, Lopez-Campos F, et al. New insights and emerging approaches in bladder-sparing treatment for muscle-invasive bladder cancer. Actas Urológicas Españolas (English Edition). 2025. https://doi.org/10.1016/j.acuroe.2025.501758.

Google Scholar 

Sun S, Wang J, Lu Y, Dai J. Corticosteroid-binding globulin, induced in testicular Leydig cells by perfluorooctanoic acid, promotes steroid hormone synthesis. Arch Toxicol. 2018;92(6):2013–25.

Google Scholar 

Sunderland EM, Hu XC, Dassuncao C, Tokranov AK, Wagner CC, Allen JG. A review of the pathways of human exposure to poly- and perfluoroalkyl substances (PFASs) and present understanding of health effects. J Expo Sci Environ Epidemiol. 2019;29(2):131–47.

Google Scholar 

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–49.

Google Scholar 

Takacs ML, Abbott BD. Activation of mouse and human peroxisome proliferator-activated receptors (alpha, beta/delta, gamma) by perfluorooctanoic acid and perfluorooctane sulfonate. Toxicol Sci. 2007;95(1):108–17.

Google Scholar 

Tamamori-Adachi M, Hayashida K, Nobori K, Omizu C, Yamada K, Sakamoto N, Kamura T, Fukuda K, Ogawa S, Nakayama KI et al: Down-regulation of p27Kip1 promotes cell proliferation of rat neonatal cardiomyocytes induced by nuclear expression of cyclin D1 and CDK4. Evidence for impaired Skp2-dependent degradation of p27 in terminal differentiation. J Biol Chem 2004, 279(48):50429–50436

Tian M, Huang Q, Wang H, Martin FL, Liu L, Zhang J, et al. Biphasic effects of perfluorooctanoic acid on steroidogenesis in mouse Leydig tumour cells. Reprod Toxicol. 2019;83:54–62.

Google Scholar 

Vieira VM, Hoffman K, Shin HM, Weinberg JM, Webster TF, Fletcher T. Perfluorooctanoic acid exposure and cancer outcomes in a contaminated community: a geographic analysis. Environ Health Perspect. 2013;121(3):318–23.

Google Scholar 

Vousden KH, Lane DP. p53 in health and disease. Nat Rev Mol Cell Biol. 2007;8(4):275–83.

Google Scholar 

Wang Z, Cousins IT, Scheringer M, Hungerbuehler K. Hazard assessment of fluorinated alternatives to long-chain perfluoroalkyl acids (PFAAs) and their precursors: status quo, ongoing challenges and possible solutions. Environ Int. 2015;75:172–9.

Google Scholar 

Wang H, Zhou C, Su B, Teng G, Zheng Y, Zhou X, et al. MCM7 expression is correlated with histological subtypes of lung adenocarcinoma and predictive of poor prognosis. Int J Clin Exp Pathol. 2017;10(12):11747–53.

Google Scholar 

Wang H, Liu J, Lou Y, Liu Y, Chen J, Liao X, et al. Identification and preliminary analysis of hub genes associated with bladder cancer progression by comprehensive bioinformatics analysis. Sci Rep. 2024;14(1):2782.

Google Scholar 

Worley RR, Moore SM, Tierney BC, Ye X, Calafat AM, Campbell S, et al. Per- and polyfluoroalkyl substances in human serum and urine samples from a residentially exposed community. Environ Int. 2017;106:135–43.

Google Scholar 

Yu YP, Landsittel D, Jing L, Nelson J, Ren B, Liu L, et al. Gene expression alterations in prostate cancer predicting tumor aggression and preceding development of malignancy. J Clin Oncol. 2004;22(14):2790–9.

Google Scholar 

Zhang T, Sun H, Qin X, Gan Z, Kannan K. PFOS and PFOA in paired urine and blood from general adults and pregnant women: assessment of urinary elimination. Environ Sci Pollut Res Int. 2015;22(7):5572–9.

Google Scholar 

Zhang Y, Zhang L, Bao J, Liu L, Wang X. Perfluorooctanoic acid exposure in early pregnancy induces oxidative stress in mice uterus and liver. Environ Sci Pollut Res Int. 2021;28(46):66355–65.

Google Scholar