Handra CM, Gurzu IL, Chirila M, Ghita I (2023) Silicosis: new challenges from an old inflammatory and fibrotic disease. Front Biosci (Landmark Ed) 28:96. https://doi.org/10.31083/j.fbl2805096

Article  CAS  PubMed  Google Scholar 

Hoy RF, Chambers DC (2020) Silica-related diseases in the modern world. Allergy 75:2805–2817. https://doi.org/10.1111/all.14202

Article  PubMed  Google Scholar 

Barnes H, Goh NSL, Leong TL, Hoy R (2019) Silica-associated lung disease: an old-world exposure in modern industries. Respirology 24:1165–1175. https://doi.org/10.1111/resp.13695

Article  PubMed  Google Scholar 

Zhang Z, Wu X, Han G, Shao B, Lin L, Jiang S (2022) Altered M1/M2 polarization of alveolar macrophages is involved in the pathological responses of acute silicosis in rats in vivo. Toxicol Ind Health 38:810–818. https://doi.org/10.1177/07482337221136949

Article  CAS  PubMed  Google Scholar 

Gentek R, Molawi K, Sieweke MH (2014) Tissue macrophage identity and self-renewal. Immunol Rev 262:56–73. https://doi.org/10.1111/imr.12224

Article  CAS  PubMed  Google Scholar 

Hirayama D, Iida T, Nakase H (2017) The phagocytic function of macrophage-enforcing innate immunity and tissue homeostasis. Int J Mol Sci 19:92. https://doi.org/10.3390/ijms19010092

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fu YL, Harrison RE (2021) Microbial phagocytic receptors and their potential involvement in cytokine induction in macrophages. Front Immunol 12:662063. https://doi.org/10.3389/fimmu.2021.662063

Article  CAS  PubMed  PubMed Central  Google Scholar 

Imamura H, Nhat KP, Togawa H, Saito K, Iino R, Kato-Yamada Y, Nagai T, Noji H (2009) Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators. Proc Natl Acad Sci U S A 106:15651–15656. https://doi.org/10.1073/pnas.0904764106

Article  PubMed  PubMed Central  Google Scholar 

Glancy B, Balaban RS (2012) Role of mitochondrial Ca2+ in the regulation of cellular energetics. Biochemistry 51:2959–2973. https://doi.org/10.1021/bi2018909

Article  CAS  PubMed  Google Scholar 

Bonora M, Patergnani S, Rimessi A, De Marchi E, Suski JM, Bononi A, Giorgi C, Marchi S, Missiroli S, Poletti F, Wieckowski MR, Pinton P (2012) ATP synthesis and storage. Purinergic Signal 8:343–357. https://doi.org/10.1007/s11302-012-9305-8

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li S, Zhao J, Han G, Zhang X, Li N, Zhang Z (2023) Silicon dioxide-induced endoplasmic reticulum stress of alveolar macrophages and its role on the formation of silicosis fibrosis: a review article. Toxicol Res (Camb) 12:1024–1033. https://doi.org/10.1093/toxres/tfad099

Article  CAS  PubMed  Google Scholar 

Lee S, Honda M, Yamamoto S, Kumagai-Takei N, Yoshitome K, Nishimura Y, Sada N, Kon S, Otsuki T (2019) Role of nephronectin in pathophysiology of silicosis. Int J Mol Sci 20:2581. https://doi.org/10.3390/ijms20102581

Article  CAS  PubMed  PubMed Central  Google Scholar 

Riteau N, Baron L, Villeret B, Guillou N, Savigny F, Ryffel B, Rassendren F, Le Bert M, Gombault A, Couillin I (2012) ATP release and purinergic signaling: a common pathway for particle-mediated inflammasome activation. Cell Death Dis 3:e403. https://doi.org/10.1038/cddis.2012.144

Article  CAS  PubMed  PubMed Central  Google Scholar 

Luna-Gomes T, Santana PT, Coutinho-Silva R (2015) Silica-induced inflammasome activation in macrophages: role of ATP and P2X7 receptor. Immunobiology 220:1101–1106. https://doi.org/10.1016/j.imbio.2015.05.004

Article  CAS  PubMed  Google Scholar 

Zhao JH, Li S, Du SL, Zhang ZQ (2024) The role of mitochondrial dysfunction in macrophages on SiO(2) -induced pulmonary fibrosis: a review. J Appl Toxicol 44:86–95. https://doi.org/10.1002/jat.4517

Article  CAS  PubMed  Google Scholar 

Lamkanfi M, Mueller JL, Vitari AC, Misaghi S, Fedorova A, Deshayes K, Lee WP, Hoffman HM, Dixit VM (2009) Glyburide inhibits the Cryopyrin/Nalp3 inflammasome. J Cell Biol 187:61–70. https://doi.org/10.1083/jcb.200903124

Article  CAS  PubMed  PubMed Central  Google Scholar 

Juliana C, Fernandes-Alnemri T, Kang S, Farias A, Qin F, Alnemri ES (2012) Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation. J Biol Chem 287:36617–36622. https://doi.org/10.1074/jbc.M112.407130

Article  CAS  PubMed  PubMed Central  Google Scholar 

Morosova KI, Aronova GV, Katsnelson BA, Velichkovski BT, Genkin AM, Elnichnykh LN, Privalova LI (1982) On the defensive action of glutamate against the cytotoxicity and fibrogenicity of quartz dust. Br J Ind Med 39:244–252. https://doi.org/10.1136/oem.39.3.244

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang L, Tian J, Ma L, Duan S (2023) Mechanistic insights into severe pulmonary inflammation caused by silica stimulation: the role of macrophage pyroptosis. Ecotoxicol Environ Saf 258:114975. https://doi.org/10.1016/j.ecoenv.2023.114975

Article  CAS  PubMed  Google Scholar 

Monção-Ribeiro LC, Faffe DS, Santana PT, Vieira FS, da Graça CL, Marques-da-Silva C, Machado MN, Caruso-Neves C, Zin WA, Borojevic R, Takiya CM, Coutinho-Silva R (2014) P2X7 receptor modulates inflammatory and functional pulmonary changes induced by silica. PLoS ONE 9:e110185. https://doi.org/10.1371/journal.pone.0110185

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang ZQ, Zhang CZ, Shao B, Pang DH, Han GZ, Lin L (2019) Effects of abnormal expression of fusion and fission genes on the morphology and function of lung macrophage mitochondria in SiO(2)-induced silicosis fibrosis in rats in vivo. Toxicol Lett 312:181–187. https://doi.org/10.1016/j.toxlet.2019.04.029

Article  CAS  PubMed  Google Scholar 

Chang M, Li N, Zhou Q, Yan Y, Xu W, Zhao Y, Yao S (2024) The inhibition of MARCO by PolyG alleviates pulmonary fibrosis via regulating mitochondrial function in a silicotic rat model. Environ Toxicol 39:3808–3819. https://doi.org/10.1002/tox.24241

Article  CAS  PubMed  Google Scholar 

Marrocco A, Ortiz LA (2022) Role of metabolic reprogramming in pro-inflammatory cytokine secretion from LPS or silica-activated macrophages. Front Immunol 13:936167. https://doi.org/10.3389/fimmu.2022.936167

Article  CAS  PubMed  PubMed Central  Google Scholar 

Thakur SA, Beamer CA, Migliaccio CT, Holian A (2009) Critical role of MARCO in crystalline silica-induced pulmonary inflammation. Toxicol Sci 108:462–471. https://doi.org/10.1093/toxsci/kfp011

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gray M, Botelho RJ (2017) Phagocytosis: hungry, hungry cells. Methods Mol Biol 1519:1–16. https://doi.org/10.1007/978-1-4939-6581-6_1

Article  CAS  PubMed  Google Scholar 

Chandak PG, Radovic B, Aflaki E, Kolb D, Buchebner M, Fröhlich E, Magnes C, Sinner F, Haemmerle G, Zechner R, Tabas I, Levak-Frank S, Kratky D (2010) Efficient phagocytosis requires triacylglycerol hydrolysis by adipose triglyceride lipase. J Biol Chem 285:20192–20201. https://doi.org/10.1074/jbc.M110.107854

Article  CAS  PubMed  PubMed Central  Google Scholar