Xu, D.F., Xu, J. & Dai, L. Myopenia and musculoskeletal aging in rheumatoid arthritis. Rheumatoid Arthritis - Other Perspectives towards a Better Practice (2020).
El-Labban, A. S., Omar, H. A., El-Shereif, R. R., Ali, F. & El-Mansoury, T. M. Pattern of young and old onset rheumatoid arthritis (YORA and EORA) among a group of egyptian patients with rheumatoid arthritis. Clin. Med. Insights Arthritis Musculoskelet. Disord. 3, 25–31 (2010).
Article PubMed PubMed Central Google Scholar
Rasch, E. K., Hirsch, R., Paulose-Ram, R. & Hochberg, M. C. Prevalence of rheumatoid arthritis in persons 60 years of age and older in the United States: effect of different methods of case classification. Arthritis Rheum. 48, 917–926 (2003).
Ma, J. D. et al. Muscle wasting, a neglected complication associated with physical dysfunction in elderly patients with rheumatoid arthritis: a cross-sectional observational study. Scand. J. Rheumatol. 50, 280–289 (2021).
Article CAS PubMed Google Scholar
Fearon, K., Evans, W. J. & Anker, S. D. Myopenia-a new universal term for muscle wasting. J. Cachexia Sarcopenia Muscle 2, 1–3 (2011).
Article PubMed PubMed Central Google Scholar
Gonzalez-Ponce, F. et al. Myostatin levels and the risk of myopenia and rheumatoid cachexia in women with rheumatoid arthritis. J. Immunol. Res 2022, 7258152 (2022).
Article PubMed PubMed Central Google Scholar
Carnac, G., Vernus, B. & Bonnieu, A. Myostatin in the pathophysiology of skeletal muscle. Curr. Genomics 8, 415–422 (2007).
Article CAS PubMed PubMed Central Google Scholar
Wabe, N. & Wiese, M. D. Treating rheumatoid arthritis to target: physician and patient adherence issues in contemporary rheumatoid arthritis therapy. J. Eval. Clin. Pr. 23, 486–493 (2017).
Aletaha, D. & Smolen, J. S. Diagnosis and management of rheumatoid arthritis: A review. JAMA 320, 1360–1372 (2018).
Mitchell, W. K. et al. Sarcopenia, dynapenia, and the impact of advancing age on human skeletal muscle size and strength; a quantitative review. Front Physiol. 3, 260 (2012).
Article PubMed PubMed Central Google Scholar
Landers-Ramos, R. Q. & Prior, S. J. The microvasculature and skeletal muscle health in aging. Exerc Sport Sci. Rev. 46, 172–179 (2018).
Article PubMed PubMed Central Google Scholar
Kunz, H. E. & Lanza, I. R. Age-associated inflammation and implications for skeletal muscle responses to exercise. Exp. Gerontol. 177, 112177 (2023).
Article CAS PubMed Google Scholar
Narici, M. V. & Maffulli, N. Sarcopenia: characteristics, mechanisms and functional significance. Br. Med Bull. 95, 139–159 (2010).
Article CAS PubMed Google Scholar
Thomas, D. R. Loss of skeletal muscle mass in aging: examining the relationship of starvation, sarcopenia and cachexia. Clin. Nutr. 26, 389–399 (2007).
Fried, L. P. et al. Frailty in older adults: Evidence for a phenotype. J. Gerontol. A Biol. Sci. Med Sci. 56, M146–M156 (2001).
Article CAS PubMed Google Scholar
Bauer, J. et al. Sarcopenia: A time for action. An SCWD position paper. J. Cachexia Sarcopenia Muscle 10, 956–961 (2019).
Article PubMed PubMed Central Google Scholar
Larsson, L. et al. Sarcopenia: aging-related loss of muscle mass and function. Physiol. Rev. 99, 427–511 (2019).
Roubenoff, R. et al. Rheumatoid cachexia: cytokine-driven hypermetabolism accompanying reduced body cell mass in chronic inflammation. J. Clin. Invest 93, 2379–2386 (1994).
Article CAS PubMed PubMed Central Google Scholar
Rajbhandary, R., Khezri, A. & Panush, R. S. Rheumatoid cachexia: What is it and why is it important? J. Rheumatol. 38, 406–408 (2011).
Roubenoff, R. Rheumatoid cachexia: a complication of rheumatoid arthritis moves into the 21st century. Arthritis Res Ther. 11, 108 (2009).
Article PubMed PubMed Central Google Scholar
Gregersen, P. K., Silver, J. & Winchester, R. J. The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum. 30, 1205–1213 (1987).
Article CAS PubMed Google Scholar
Mattey, D. L. et al. Independent association of rheumatoid factor and the HLA-DRB1 shared epitope with radiographic outcome in rheumatoid arthritis. Arthritis Rheum. 44, 1529–1533 (2001).
Article CAS PubMed Google Scholar
Weyand, C. M., Hicok, K. C., Conn, D. L. & Goronzy, J. J. The influence of HLA-DRB1 genes on disease severity in rheumatoid arthritis. Ann. Intern Med 117, 801–806 (1992).
Article CAS PubMed Google Scholar
Gonzalez-Gay, M. A. et al. Seronegative rheumatoid arthritis in elderly and polymyalgia rheumatica have similar patterns of HLA association. J. Rheumatol. 28, 122–125 (2001).
Kim, E. J. et al. Shared epitope and radiologic progression are less prominent in elderly onset RA than young onset RA. Rheumatol. Int 33, 2135–2140 (2013).
Article CAS PubMed Google Scholar
Hellier, J. P., Eliaou, J. F., Daurès, J. P., Sany, J. & Combe, B. HLA-DRB1 genes and patients with late onset rheumatoid arthritis. Ann. Rheum. Dis. 60, 531–533 (2001).
Article CAS PubMed PubMed Central Google Scholar
Wu, H. et al. Interaction between RANKL and HLA-DRB1 genotypes may contribute to younger age at onset of seropositive rheumatoid arthritis in an inception cohort. Arthritis Rheum. 50, 3093–3103 (2004).
Article CAS PubMed Google Scholar
Zhang, T. P. et al. The contribution of genetic variation and aberrant methylation of aryl hydrocarbon receptor signaling pathway genes to rheumatoid arthritis. Front Immunol. 13, 823863 (2022).
Article CAS PubMed PubMed Central Google Scholar
Huang, H. et al. Identification of key candidate genes and pathways in rheumatoid arthritis and osteoarthritis by integrated bioinformatical analysis. Front Genet 14, 1083615 (2023).
Article CAS PubMed PubMed Central Google Scholar
Garatachea, N. & Lucía, A. Genes and the ageing muscle: A review on genetic association studies. Age (Dordr.) 35, 207–233 (2013).
Article CAS PubMed Google Scholar
Wen, Y. P. & Yu, Z. G. Identifying shared genetic loci and common risk genes of rheumatoid arthritis associated with three autoimmune diseases based on large-scale cross-trait genome-wide association studies. Front Immunol. 14, 1160397 (2023).
Article CAS PubMed PubMed Central Google Scholar
Shao, M. et al. Association of interleukin-6 promoter polymorphism with rheumatoid arthritis: a meta-analysis with trial sequential analysis. Clin. Rheumatol. 41, 411–419 (2022).
Punzi, L. et al. Synovial fluid levels of proinflammatory interleukins and their inter-relationships in elderly vs younger onset rheumatoid arthritis. Aging (Milano) 8, 277–281 (1996).
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