Pereira MI, Medeiros JA. Role of Helicobacter pylori in gastric mucosa-associated lymphoid tissue lymphomas. World J Gastroenterol: WJG. 2014;20(3):684.
Article PubMed PubMed Central Google Scholar
Saxena A, Mukhopadhyay AK, Nandi SP. Helicobacter pylori: perturbation and restoration of gut microbiome. J Biosci. 2020;45:1–15.
Thung I, Aramin H, Vavinskaya V, Gupta S, Park JY, Crowe SE, Valasek MA. the global emergence of Helicobacter pylori antibiotic resistance. Aliment Pharmacol Ther. 2016;43(4):514–33.
Article CAS PubMed Google Scholar
Matos R, Amorim I, Magalhães A, Haesebrouck F, Gärtner F, Reis CA. Adhesion of Helicobacter species to the human gastric mucosa: a deep look into glycans role. Front Mol Biosci. 2021;8:656439.
Article CAS PubMed PubMed Central Google Scholar
BangaNdzouboukou JL, Lei Q, Ullah N, Zhang Y, Hao L, Fan X. Helicobacter pylori adhesins: HpaA a potential antigen in experimental vaccines for H pylori. Helicobacter. 2021;26(1):e12758.
Schoep TD, Fulurija A, Good F, Lu W, Himbeck RP, Schwan C, Marshall BJ. Surface properties of Helicobacter pylori urease complex are essential for persistence. PLoS One. 2010;5(11):e15042.
Article CAS PubMed PubMed Central Google Scholar
Carlsohn E, Nyström J, Bölin I, Nilsson CL, Svennerholm AM. HpaA is essential for Helicobacter pylori colonization in mice. Infect Immun. 2006;74(2):920–6.
Article CAS PubMed PubMed Central Google Scholar
Pan X, Pan L. Protection against Helicobacter pylori infection in BALB/c mouse model by oral administration of multivalent epitope-based vaccine of cholera toxin B subunit-HUUC. Front Immunol. 2018;9:344572.
Benoit S, Maier RJ. Dependence of Helicobacter pylori urease activity on the nickel-sequestering ability of the UreE accessory protein. J Bacteriol. 2003;185(16):4787–95.
Article CAS PubMed PubMed Central Google Scholar
Ansari S, Yamaoka Y. Survival of Helicobacter pylori in gastric acidic territory. Helicobacter. 2017;22(4):e12386.
Lee MH, Roussel Y, Wilks M, Tabaqchali S. Expression of Helicobacter pylori urease subunit B gene in Lactococcus lactis MG1363 and its use as a vaccine delivery system against H pylori infection in mice. Vaccine. 2001;19(28–29):3927–35.
Article CAS PubMed Google Scholar
Rahimi E, Ameri M, Doosti A, Gholampour AR. Occurrence of toxigenic Vibrio parahaemolyticus strains in shrimp in Iran. Foodborne Pathog Dis. 2010;7(9):1107–11.
Mejías-Luque R., & Gerhard M. (2017). Immune evasion strategies and persistence of Helicobacter pylori. Molecular Pathogenesis and Signal Transduction by Helicobacter pylori. 53–71
Rosenbaum P, Tchitchek N, Joly C, Rodriguez Pozo A, Stimmer L, Langlois S, Martinon F. Vaccine inoculation route modulates early immunity and consequently antigen-specific immune response. Frontiers Immunol. 2021;12:645210.
Chehelgerdi M, Heidarnia F, Dehkordi FB, Chehelgerdi M, Khayati S, Khorramian-Ghahfarokhi M, Kabiri H. Immunoinformatic prediction of potential immunodominant epitopes from cagW in order to investigate protection against Helicobacter pylori infection based on experimental consequences. Funct Integr Genom. 2023;23(2):107.
Azadbakht N, Doosti A, Jami MS. CRISPR/Cas9-mediated LINC00511 knockout strategies, increased apoptosis of breast cancer cells via suppressing antiapoptotic genes. Biol Proced Online. 2022;24(1):8.
Liu KY, Shi Y, Luo P. Therapeutic efficacy of oral immunization with attenuated Salmonella typhimurium expressing Helicobacter pylori CagA, VacA and UreB fusion proteins in mice model. Vaccine. 2011;29(38):6679–85.
Article CAS PubMed Google Scholar
Hobernik D, Bros M. DNA vaccines—how far from clinical use? Int J Mol Sci. 2018;19(11):3605.
Article PubMed PubMed Central Google Scholar
Zhou WY, Shi Y, Wu C, Zhang WJ, Mao XH, Guo G, Zou QM. Therapeutic efficacy of a multi-epitope vaccine against Helicobacter pylori infection in BALB/c mice model. Vaccine. 2009;27(36):5013–9.
Article CAS PubMed Google Scholar
Lee J, Kumar SA, Jhan YY, Bishop CJ. Engineering DNA vaccines against infectious diseases. Acta Biomater. 2018;15(80):31–47.
Kim C, Hovakimyan A, Zagorski K, Antonyan T, Petrushina I, Davtyan H, Agadjanyan MG. Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies. NPJ Vaccines. 2022;7(1):1.
Article CAS PubMed PubMed Central Google Scholar
Kaveh-Samani A, Dalali S, Kaviani F, Piri-Gharaghie T, Doosti A. Oral administration of DNA alginate nanovaccine induced immune-protection against Helicobacter pylori in Balb/C mice. BMC Immunol. 2024;25(1):11.
Article CAS PubMed PubMed Central Google Scholar
Guo L, Yin R, Xu G, Gong X, Chang Z, Hong D, Liu K. Immunologic properties and therapeutic efficacy of a multivalent epitope-based vaccine against four Helicobacter pylori adhesins (urease, Lpp20, HpaA, and CagL) in Mongolian gerbils. Helicobacter. 2017;22(6):e12428.
Bosschem I, Bayry J, De Bruyne E, Van Deun K, Smet A, Vercauteren G, Flahou B. Effect of different adjuvants on protection and side-effects induced by Helicobacter suis whole-cell lysate vaccination. PloS One. 2015;10(6):e0131364.
Article PubMed PubMed Central Google Scholar
Mirzaei N, Poursina F, Moghim S, Rashidi N, GhasemianSafaei H. The study of H pylori putative candidate factors for single-and multi-component vaccine development. Crit Rev Microbiol. 2017;43(5):631–50.
Article CAS PubMed Google Scholar
Wilson CC, Newman MJ, Livingston BD, MaWhinney S, Forster JE, Scott J, Benson CA. Clinical phase 1 testing of the safety and immunogenicity of an epitope-based DNA vaccine in human immunodeficiency virus type 1-infected subjects receiving highly active antiretroviral therapy. Clin Vaccine Immunol. 2008;15(6):986–94.
Article CAS PubMed PubMed Central Google Scholar
De Groot AS, McMurry J, Marcon L, Franco J, Rivera D, Kutzler M, Martin B. Developing an epitope-driven tuberculosis (TB) vaccine. Vaccine. 2005;23(17–18):2121–31.
Jafarzadeh A, Larussa T, Nemati M, Jalapour S. T cell subsets play an important role in the determination of the clinical outcome of Helicobacter pylori infection. Microb Pathog. 2018;116:227–36.
Article CAS PubMed Google Scholar
Romagnani S. Th1/th2 cells. Inflamm Bowel Dis. 1999;5(4):285–94.
Article CAS PubMed Google Scholar
Bagheri N, Salimzadeh L, Shirzad H. The role of T helper 1-cell response in Helicobacter pylori-infection. Microb Pathog. 2018;123:1–8.
Article CAS PubMed Google Scholar
Shi Y, Liu XF, Zhuang Y, Zhang JY, Liu T, Yin Z, Zou QM. Helicobacter pylori-induced Th17 responses modulate Th1 cell responses, benefit bacterial growth, and contribute to pathology in mice. J Immunol. 2010;184(9):5121–9.
Article CAS PubMed Google Scholar
Bretscher PA. On the mechanism determining the TH1/TH2 phenotype of an immune response, and its pertinence to strategies for the prevention, and treatment, of certain infectious diseases. Scand J Immunol. 2014;79(6):361–76.
Article CAS PubMed PubMed Central Google Scholar
Moyat M, Velin D. Immune responses to Helicobacter pylori infection. World J Gastroenterol WJG. 2014;20(19):5583.
Article CAS PubMed Google Scholar
Dooyema SD, Noto JM, Wroblewski LE, Piazuelo MB, Krishna U, Suarez G, Peek RM. Helicobacter pylori actively suppresses innate immune nucleic acid receptors. Gut Microbes. 2022;14(1):2105102.
Comments (0)