Debaigt C, Hirling H, Steiner P, Vincent JP, Mazella J. Crucial role of neuron-enriched endosomal protein of 21 kDa in sorting between degradation and recycling of internalized G-protein-coupled receptors. J Biol Chem. 2004;279:35687–91.
Article CAS PubMed Google Scholar
Muthusamy N, Faundez V, Bergson C. Calcyon, a mammalian specific NEEP21 family member, interacts with adaptor protein complex 3 (AP-3) and regulates targeting of AP-3 cargoes. J Neurochem. 2012;123:60–72.
Article CAS PubMed Google Scholar
Davidson HT, Xiao J, Dai R, Bergson C. Calcyon is necessary for activity-dependent AMPA receptor internalization and LTD in CA1 neurons of hippocampus. Eur J Neurosci. 2009;29:42–54.
Article PubMed PubMed Central Google Scholar
Steiner P, Alberi S, Kulangara K, Yersin A, Sarria JC, Regulier E, et al. Interactions between NEEP21, GRIP1 and GluR2 regulate sorting and recycling of the glutamate receptor subunit GluR2. EMBO J. 2005;24:2873–84.
Article CAS PubMed PubMed Central Google Scholar
Norstrom EM, Zhang C, Tanzi R, Sisodia SS. Identification of NEEP21 as a ss-amyloid precursor protein-interacting protein in vivo that modulates amyloidogenic processing in vitro. J Neuroscience: Official J Soc Neurosci. 2010;30:15677–85.
Plooster M, Rossi G, Farrell MS, McAfee JC, Bell JL, Ye M, et al. Schizophrenia-Linked protein tSNARE1 regulates endosomal trafficking in cortical neurons. J Neurosci. 2021;41:9466–81.
Article CAS PubMed PubMed Central Google Scholar
Yin DM, Chen YJ, Liu S, Jiao H, Shen C, Sathyamurthy A, et al. Calcyon stimulates neuregulin 1 maturation and signaling. Mol Psychiatry. 2015;20:1251–60.
Article CAS PubMed Google Scholar
Alberi S, Boda B, Steiner P, Nikonenko I, Hirling H, Muller D. The endosomal protein NEEP21 regulates AMPA receptor-mediated synaptic transmission and plasticity in the hippocampus. Mol Cell Neurosci. 2005;29:313–9.
Article CAS PubMed Google Scholar
Vazdarjanova A, Bunting K, Muthusamy N, Bergson C. Calcyon upregulation in adolescence impairs response inhibition and working memory in adulthood. Mol Psychiatry. 2011;16:672–84.
Article CAS PubMed PubMed Central Google Scholar
Xiao J, Dai R, Negyessy L, Bergson C. Calcyon, a novel partner of clathrin light chain, stimulates clathrin-mediated endocytosis. J Biol Chem. 2006;281:15182–93.
Article CAS PubMed Google Scholar
Kruusmagi M, Zelenin S, Brismar H, Scott L. Intracellular dynamics of calcyon, a neuron-specific vesicular protein. NeuroReport. 2007;18:1547–51.
Article CAS PubMed Google Scholar
Austin R, Chander P, Zimmerman AJ, Overby M, Digilio L, Yap CC, et al. Global loss of Neuron-specific gene 1 causes alterations in motor coordination, increased anxiety, and diurnal hyperactivity in male mice. Genes Brain Behav. 2022;21:e12816.
Article CAS PubMed PubMed Central Google Scholar
Trantham-Davidson H, Vazdarjanova A, Dai R, Terry A, Bergson C. Up-regulation of calcyon results in locomotor hyperactivity and reduced anxiety in mice. Behav Brain Res. 2008;189:244–9.
Article CAS PubMed PubMed Central Google Scholar
Muthusamy N, Ahmed SA, Rana BK, Navarre S, Kozlowski DJ, Liberles DA, et al. Phylogenetic analysis of the NEEP21/calcyon/P19 family of endocytic proteins: evidence for functional evolution in the vertebrate CNS. J Mol Evol. 2009;69:319–32.
Article CAS PubMed PubMed Central Google Scholar
Chander P, Kennedy MJ, Winckler B, Weick JP. Neuron-specific gene 2 (NSG2) encodes an AMPA receptor interacting protein that modulates excitatory neurotransmission. eNeuro. 2019;6.
Barford K, Yap CC, Dwyer ND, Winckler B. The related neuronal endosomal proteins NEEP21 (Nsg1) and P19 (Nsg2) have divergent expression profiles in vivo. J Comp Neurol. 2017;525:1861–78.
Article CAS PubMed PubMed Central Google Scholar
Aboghazleh R, Boyajian SD, Atiyat A, Udwan M, Al-Helalat M, Al-Rashaideh R. Rodent brain extraction and dissection: a comprehensive approach. MethodsX. 2024;12:102516.
Article CAS PubMed Google Scholar
Braun AA, Skelton MR, Vorhees CV, Williams MT. Comparison of the elevated plus and elevated zero mazes in treated and untreated male Sprague-Dawley rats: effects of anxiolytic and anxiogenic agents. Pharmacol Biochem Behav. 2011;97:406–15.
Article CAS PubMed Google Scholar
Freeman D, Sheaves B, Waite F, Harvey AG, Harrison PJ. Sleep disturbance and psychiatric disorders. Lancet Psychiatry. 2020;7:628–37.
Zhang Y, Ren R, Yang L, Zhang H, Shi Y, Okhravi HR, et al. Sleep in Alzheimer’s disease: a systematic review and meta-analysis of polysomnographic findings. Transl Psychiatry. 2022;12:136.
Article PubMed PubMed Central Google Scholar
Izquierdo A, Brigman JL, Radke AK, Rudebeck PH, Holmes A. The neural basis of reversal learning: an updated perspective. Neuroscience. 2017;345:12–26.
Article CAS PubMed Google Scholar
Schoenbaum G, Saddoris MP, Stalnaker TA. Reconciling the roles of orbitofrontal cortex in reversal learning and the encoding of outcome expectancies. Ann N Y Acad Sci. 2007;1121:320–35.
Article PubMed PubMed Central Google Scholar
Marquardt K, Sigdel R, Brigman JL. Touch-screen visual reversal learning is mediated by value encoding and signal propagation in the orbitofrontal cortex. Neurobiol Learn Mem. 2017;139:179–88.
Article PubMed PubMed Central Google Scholar
Brigman JL, Daut RA, Wright T, Gunduz-Cinar O, Graybeal C, Davis MI, et al. GluN2B in corticostriatal circuits governs choice learning and choice shifting. Nat Neurosci. 2013;16:1101–10.
Article CAS PubMed PubMed Central Google Scholar
Chandrasekaran J, Caldwell KK, Brigman JL. Dynamic regulation of corticostriatal glutamatergic synaptic expression during reversal learning in male mice. Neurobiol Learn Mem. 2024;208:107892.
Article CAS PubMed Google Scholar
Marquardt K, Josey M, Kenton JA, Cavanagh JF, Holmes A, Brigman JL. Impaired cognitive flexibility following NMDAR-GluN2B deletion is associated with altered orbitofrontal-striatal function. Neuroscience. 2019;404:338–52.
Article CAS PubMed Google Scholar
Brigman JL, Feyder M, Saksida LM, Bussey TJ, Mishina M, Holmes A. Impaired discrimination learning in mice lacking the NMDA receptor NR2A subunit. Learn Mem. 2008;15:50–4.
Vorhees CV, Williams MT. Morris water maze: procedures for assessing spatial and related forms of learning and memory. Nat Protoc. 2006;1:848–58.
Article PubMed PubMed Central Google Scholar
Whishaw IQ, McKenna JE, Maaswinkel H. Hippocampal lesions and path integration. Curr Opin Neurobiol. 1997;7:228–34.
Article CAS PubMed Google Scholar
Noor S, Sun MS, Vanderwall AG, Havard MA, Sanchez JE, Harris NW, et al. LFA-1 antagonist (BIRT377) similarly reverses peripheral neuropathic pain in male and female mice with underlying sex divergent peripheral immune proinflammatory phenotypes. Neuroimmunol Neuroinflamm. 2019;6:10.
CAS PubMed PubMed Central Google Scholar
Muthusamy N, Chen YJ, Yin DM, Mei L, Bergson C. Complementary roles of the neuron-enriched endosomal proteins NEEP21 and calcyon in neuronal vesicle trafficking. J Neurochem. 2015;132:20–31.
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