Highly sensitive indirect competitive enzyme-linked immunosorbent assay based on a monoclonal antibody against saikosaponin b2 for quality control of Kampo medicines containing Bupleuri radix

Yang F, Dong X, Yin X, Wang W, You L, Ni J (2017) Radix Bupleuri: a review of traditional uses, botany, phytochemistry, pharmacology, and toxicology. BioMed Res Int 2017:7597596. https://doi.org/10.1155/2017/7597596

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li X, Li X, Huang N, Liu R, Sun R (2018) A comprehensive review and perspectives on pharmacology and toxicology of saikosaponins. Phytomedicine 50:73–87. https://doi.org/10.1016/j.phymed.2018.09.174

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kim BM (2018) The role of saikosaponins in therapeutic strategies for age-related diseases. Oxid Med Cell Longev 2018:8275256. https://doi.org/10.1155/2018/8275256

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lee TH, Park S, You MH, Lim JH, Min SH, Kim BM (2016) A potential therapeutic effect of saikosaponin C as a novel dual-target anti-Alzheimer agent. J Neurochem 136:1232–1245. https://doi.org/10.1111/jnc.13515

Article  CAS  PubMed  Google Scholar 

Lu CN, Yuan ZG, Zhang XL, Yan R, Zhao YQ, Liao M, Chen JX (2012) Saikosaponin a and its epimer saikosaponin d exhibit anti-inflammatory activity by suppressing activation of NF-κB signaling pathway. Int Immunopharmacol 14:121–126. https://doi.org/10.1016/j.intimp.2012.06.010

Article  CAS  PubMed  Google Scholar 

Xu L, Su J, Guo L, Wang S, Deng X, Ma S (2019) Modulation of LPA1 receptor-mediated neuronal apoptosis by Saikosaponin-d: a target involved in depression. Neuropharmacology 155:150–161. https://doi.org/10.1016/j.neuropharm.2019.05.027

Article  CAS  PubMed  Google Scholar 

Li HY, Zhao YH, Zeng MJ, Fang F, Li M, Qin TT, Ye LY, Li HW, Qu R, Ma SP (2017) Saikosaponin D relieves unpredictable chronic mild stress induced depressive-like behavior in rats: involvement of HPA axis and hippocampal neurogenesis. Psychopharmacology 234:3385–3394. https://doi.org/10.1007/s00213-017-4720-8

Article  CAS  PubMed  Google Scholar 

Lin LT, Chung CY, Hsu WC, Chang SP, Hung TC, Shields J, Russell RS, Lin CC, Li CF, Yen MH, Tyrrell DL, Lin CC, Richardson CD (2015) Saikosaponin b2 is a naturally occurring terpenoid that efficiently inhibits hepatitis C virus entry. J Hepatol 62:541–548. https://doi.org/10.1016/j.jhep.2014.10.040

Article  CAS  PubMed  Google Scholar 

Lee WP, Lan KL, Liao SX, Huang YH, Hou MC, Lan KH (2019) Antiviral effect of saikosaponin B2 in combination with daclatasvir on NS5A resistance-associated substitutions of hepatitis C virus. J Chin Med Assoc 82:368–374. https://doi.org/10.1097/JCMA.0000000000000095

Article  PubMed  Google Scholar 

Omrani M, Keshavarz M, Nejad Ebrahimi S, Mehrabi M, McGaw LJ, Ali Abdalla M, Mehrbod P (2020) Potential natural products against respiratory viruses: a perspective to develop anti-COVID-19 medicines. Front Pharmacol 11:586993. https://doi.org/10.3389/fphar.2020.586993

Article  CAS  PubMed  Google Scholar 

Kim BM, Hong SH (2011) Sequential caspase-2 and caspase-8 activation is essential for saikosaponin a-induced apoptosis of human colon carcinoma cell lines. Apoptosis 16:184–197. https://doi.org/10.1007/s10495-010-0557-x

Article  CAS  PubMed  Google Scholar 

Wong VK, Zhang MM, Zhou H, Lam KY, Chan PL, Law CK, Yue PY, Liu L (2013) Saikosaponin-d enhances the anticancer potency of TNF-α via overcoming its undesirable response of activating NF-kappa B signalling in cancer cells. Evid Based Complement Alternat Med 2013:745295. https://doi.org/10.1155/2013/745295

Article  PubMed  PubMed Central  Google Scholar 

Wang P, Ren J, Tang J, Zhang D, Li B, Li Y (2010) Estrogen-like activities of saikosaponin-d in vitro: a pilot study. Eur J Pharmacol 626:159–165. https://doi.org/10.1016/j.ejphar.2009.09.047

Article  CAS  PubMed  Google Scholar 

Chen XQ, Chen SJ, Liang WN, Wang M, Li CF, Wang SS, Dong SQ, Yi LT, Li CD (2018) Saikosaponin A attenuates perimenopausal depression-like symptoms by chronic unpredictable mild stress. Neurosci Lett 662:283–289. https://doi.org/10.1016/j.neulet.2017.09.046

Article  CAS  PubMed  Google Scholar 

Ministry of Health (2022) LaWoJ. Japanese pharmacopoeia, 18th ed. http://www.mhlw.go.jp/topics/bukyoku/iyaku/yakkyoku/english.html. Accessed 2023

Kimata H, Hiyama C, Yahara S, Tanaka O, Ishikawa O, Aiura M (1979) Application of high performance liquid chromatography to the analysis of crude drugs: Separatory determination of saponins of Bupleuri radix. Chem Pharm Bull 27:1836–1841. https://doi.org/10.1248/cpb.27.1836

Article  CAS  Google Scholar 

Ebata N, Nakajima K, Hayashi K, Okada M, Maruno M (1996) Saponins from the root of Bupleurum falcatum. Phytochemistry 41:895–901. https://doi.org/10.1016/0031-9422(95)00720-2

Article  CAS  PubMed  Google Scholar 

Tian RT, Xie PS, Liu HP (2009) Evaluation of traditional Chinese herbal medicine: Chaihu (Bupleuri Radix) by both high-performance liquid chromatographic and high-performance thin-layer chromatographic fingerprint and chemometric analysis. J Chromatogr A 1216:2150–2155. https://doi.org/10.1016/j.chroma.2008.10.127

Article  CAS  PubMed  Google Scholar 

Li XQ, Gao QT, Chen XH, Bi KS (2005) High performance liquid chromatographic assay of saikosaponins from radix Bupleuri in China. Biol Pharm Bull 28:1736–1742. https://doi.org/10.1248/bpb.28.1736

Article  CAS  PubMed  Google Scholar 

Park IS, Kang EM, Kim N (2000) High-performance liquid chromatographic analysis of saponin compounds in Bupleurum falcatum. J Chromatogr Sci 38:229–233. https://doi.org/10.1093/chromsci/38.6.229

Article  CAS  PubMed  Google Scholar 

Lee J, Yang DH, Suh JH, Kim U, Eom HY, Kim J, Lee MY, Kim J, Han SB (2011) Species discrimination of Radix Bupleuri through the simultaneous determination of ten saikosaponins by high performance liquid chromatography with evaporative light scattering detection and electrospray ionization mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 879:3887–3895. https://doi.org/10.1016/j.jchromb.2011.10.040

Article  CAS  PubMed  Google Scholar 

Eom HY, Park SY, Kim MK, Suh JH, Yeom H, Min JW, Kim U, Lee J, Youm JR, Han SB (2010) Comparison between evaporative light scattering detection and charged aerosol detection for the analysis of saikosaponins. J Chromatogr A 1217:4347–4354. https://doi.org/10.1016/j.chroma.2010.04.047

Article  CAS  PubMed  Google Scholar 

Zhou Y, Lin Y, Liu X, Ju W (2015) Simultaneous determination of 12 index components and compatibility changes in Longchai decoction by liquid chromatography-mass spectrometry. J Chromatogr Sci 53:60–65. https://doi.org/10.1093/chromsci/bmu015

Article  CAS  PubMed  Google Scholar 

Sun T, Luo J, Xu Y, Sun X, Yang S, Yang M (2021) Ultra-high performance supercritical fluid chromatography method for separation and quantitation of saikosaponins in herbal medicine. J Pharm Biomed Anal 199:114039. https://doi.org/10.1016/j.jpba.2021.114039

Article  CAS  PubMed  Google Scholar 

Ma H, Ó’Fágáin C, O’Kennedy R (2020) Antibody stability: a key to performance - analysis, influences and improvement. Biochimie 177:213–225. https://doi.org/10.1016/j.biochi.2020.08.019

Article  CAS  PubMed  Google Scholar 

Sakamoto S, Putalun W, Vimolmangkang S, Phoolcharoen W, Shoyama Y, Tanaka H, Morimoto S (2018) Enzyme-linked immunosorbent assay for the quantitative/qualitative analysis of plant secondary metabolites. J Nat Med 72:32–42. https://doi.org/10.1007/s11418-017-1144-z

Article  CAS  PubMed  Google Scholar 

Nuntawong P, Putalun W, Tanaka H, Morimoto S, Sakamoto S (2022) Lateral flow immunoassay for small-molecules detection in phytoproducts: a review. J Nat Med 76:521–545. https://doi.org/10.1007/s11418-022-01605-6

Article  PubMed  PubMed Central  Google Scholar 

Fujii S, Morinaga O, Uto T, Nomura S, Shoyama Y (2014) Development of a monoclonal antibody-based immunochemical assay for liquiritin and its application to the quality control of licorice products. J Agric Food Chem 62:3377–3383. https://doi.org/10.1021/jf404731z

Article  CAS  PubMed  Google Scholar 

Sakamoto S, Yusakul G, Pongkitwitoon B, Paudel MK, Tanaka H, Morimoto S (2015) Simultaneous determination of soy isoflavone glycosides, daidzin and genistin by monoclonal antibody-based highly sensitive indirect competitive enzyme-linked immunosorbent assay. Food Chem 169:127–133. https://doi.org/10.1016/j.foodchem.2014.08.004

Article  CAS  PubMed  Google Scholar 

Fujii S, Ohta T, Ehama R, Irikida M, Nomura S, Shoyama Y, Uto T (2023) Development of an indirect competitive enzyme-linked immunosorbent assay for formononetin and its application in a cell-based assay using MC3T3-E1 cells. Food Chem 403:134339. https://doi.org/10.1016/j.foodchem.2022.134339

Article  CAS  PubMed  Google Scholar 

Fujii S, Tuvshintogtokh I, Mandakh B, Munkhjargal B, Uto T, Morinaga O, Shoyama Y (2014) Screening of Glycyrrhiza uralensis Fisch. ex DC. containing high concentrations of glycyrrhizin by Eastern blotting and enzyme-linked immunosorbent assay using anti-glycyrrhizin monoclonal antibody for selective breeding of licorice. J Nat Med 68:717–722. https://doi.org/10.1007/s11418-014-0847-7

Article  CAS  PubMed  Google Scholar 

Paudel MK, Sakamoto S, Huy LV, Tanaka H, Miyamoto T, Takano A, Morimoto S (2017) Development of an immunoassay using an anti-wogonin glucuronide monoclonal antibody. J Immunoassay Immunochem 38:457–470. https://doi.org/10.1080/15321819.2016.1273236

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