Y. Liu, S.Y. Ye, S. He et al., Single-cell and Spatial transcriptome analyses reveal tertiary lymphoid structures linked to tumour progression and immunotherapy response in nasopharyngeal carcinoma. Nat. Commun. 15(1), 7713 (2024)
Article CAS PubMed PubMed Central Google Scholar
Q. Liu, H. Wang, Z. Chen et al., Global, regional, and National epidemiology of nasopharyngeal carcinoma in middle-aged and elderly patients from 1990 to 2021. Ageing Res. Rev. 104, 102613 (2025)
Article CAS PubMed Google Scholar
P. Feng, Y. Wang, N. Liu et al., High expression of PPP1CC promotes NHEJ-mediated DNA repair leading to radioresistance and poor prognosis in nasopharyngeal carcinoma. Cell. Death Differ. 31(5), 683–696 (2024)
Article CAS PubMed PubMed Central Google Scholar
J. Chen, C. Feng, Y. Lan et al., Bidirectional regulation of reactive oxygen species for radiosensitization in nasopharyngeal carcinoma. J. Nanobiotechnol. 23(1), 96 (2025)
N. Miao, D. Cao, J. Jin et al., Tumor cell-intrinsic Piezo2 drives radioresistance by impairing CD8 + T cell stemness maintenance. J. Exp. Med. 221(10), e20231486 (2024)
Article CAS PubMed PubMed Central Google Scholar
W. Liu, J. Niu, Y. Huo et al., Role of circular RNAs in cancer therapy resistance. Mol. Cancer. 24(1), 55 (2025)
Article PubMed PubMed Central Google Scholar
X. Li, H. Liu, W. Gao et al., Octadecyl gallate and Lipid-Modified MnSe2 nanoparticles enhance radiosensitivity in esophageal squamous cell carcinoma and promote radioprotection in normal tissues. Adv. Mater. 36(23), e2311291 (2024)
Z. Shi, C. Hu, X. Zheng, C. Sun, Q. Li, Feedback loop between hypoxia and energy metabolic reprogramming aggravates the radioresistance of cancer cells. Exp. Hematol. Oncol. 13(1), 55 (2024)
Article CAS PubMed PubMed Central Google Scholar
X. Cao, Z. Yan, Z. Chen et al., The emerging role of deubiquitinases in radiosensitivity. Int. J. Radiat. Oncol. Biol. Phys. 118(5), 1347–1370 (2024)
H.Y. Chan, Q. Wang, A. Howie, J. Bucci, P. Graham, Y. Li, Extracellular vesicle biomarkers redefine prostate cancer radiotherapy. Cancer Lett. 616, 217568 (2025)
Article CAS PubMed Google Scholar
Y. Zhou, Y. Xiao, H. Liu et al., Elevation of H3K27me3 level contributes to the radioresistance of nasopharyngeal carcinoma by inhibiting OAS1 expression. Am. J. Physiol. Cell. Physiol. 326(1), C60–C73 (2024)
R. Zhang, Y. Shen, X. Zhou et al., Hypoxia-tropic delivery of nanozymes targeting transferrin receptor 1 for nasopharyngeal carcinoma radiotherapy sensitization. Nat. Commun. 16(1), 890 (2025)
Article CAS PubMed PubMed Central Google Scholar
M. Labbé, M. Chang, B. Saintpierre et al., Loss of miR-200c-3p promotes resistance to radiation therapy via the DNA repair pathway in prostate cancer. Cell. Death Dis. 15(10), 751 (2024)
Article PubMed PubMed Central Google Scholar
X.L. Wu, Y.N. Guo, Role of cellular senescence genes and immune infiltration in sepsis and sepsis-Induced ARDS based on bioinformatics analysis. J. Inflamm. Res. 17, 9119–9133 (2024)
Article CAS PubMed PubMed Central Google Scholar
D. Pu, Y. Xu, H. Yu et al., Comprehensive pan-cancer analysis reveals CDC6 as a potential Immunomodulatory agent and promising therapeutic target in pancreatic cancer. Transl Cancer Res. 13(8), 4096–4112 (2024)
Article CAS PubMed PubMed Central Google Scholar
S. Guo, S. Xing, Z. Wu et al., Leucine restriction ameliorates Fusobacterium nucleatum-driven malignant progression and radioresistance in nasopharyngeal carcinoma. Cell. Rep. Med. 5(10), 101753 (2024)
Article CAS PubMed PubMed Central Google Scholar
J. Liao, X. Qing, X. Li et al., TRAF4 regulates ubiquitination-modulated survivin turnover and confers radioresistance. Int. J. Biol. Sci. 20(1), 182–199 (2024)
Article CAS PubMed PubMed Central Google Scholar
Z.Q. Long, R. Ding, T.Q. Quan et al., Multi-Omics characterization of Genome-Wide abnormal DNA methylation reveals FGF5 as a diagnosis of nasopharyngeal carcinoma recurrence after radiotherapy. Biomolecules. 15(2), 283 (2025)
Article CAS PubMed PubMed Central Google Scholar
M. Rezapour, R. Wesolowski, M.N. Gurcan, Identifying key genes involved in axillary lymph node metastasis in breast cancer using advanced RNA-Seq analysis: A methodological approach with GLMQL and MAS. Int. J. Mol. Sci. 2024. 25(13)
P. Yanatatsaneejit, T. Chalermchai, V. Kerekhanjanarong et al., Promoter hypermethylation of CCNA1, RARRES1, and HRASLS3 in nasopharyngeal carcinoma. Oral Oncol. 44(4), 400–406 (2008)
Article CAS PubMed Google Scholar
N.M. Gašperov, I. Sabol, P. Planinić et al., Methylated host cell gene promoters and human papillomavirus type 16 and 18 predicting cervical lesions and cancer. PLoS One. 10(6), e0129452 (2015)
J. Kuan-Chun, Huang et al., Cyclin A1 expression and paclitaxel resistance in human ovarian cancer cells (EUROPEAN JOURNAL OF CANCER, 2016)
Y. Zhan, S. Fan, Multiple mechanisms involving in radioresistance of nasopharyngeal carcinoma. J. Cancer. 11(14), 4193–4204 (2020)
Article CAS PubMed PubMed Central Google Scholar
Y. Guo, Y. Zhang, S.J. Zhang, Y.N. Ma, Y. He, Comprehensive analysis of key genes and MicroRNAs in radioresistant nasopharyngeal carcinoma. BMC Med. Genomics. 12(1), 1–10 (2019)
J.N. Moloney, T.G. Cotter, ROS signalling in the biology of cancer. Semin Cell. Dev. Biol. 80, 50–64 (2017)
K. Iskandar, J. Foo, A. Liew et al., A novel MTORC2-AKT-ROS axis triggers mitofission and mitophagy-associated execution of colorectal cancer cells upon drug-induced activation of mutant KRAS. Autophagy. 20(6), 1418–1441 (2024)
Article CAS PubMed PubMed Central Google Scholar
Z. Ling, J. Pan, Z. Zhang et al., Small-molecule molephantin induces apoptosis and mitophagy flux blockage through ROS production in glioblastoma. Cancer Lett. 592, 216927 (2024)
Article CAS PubMed Google Scholar
W. Li, Q. Zeng, B. Wang et al., Oxidative stress promotes oral carcinogenesis via Thbs1-mediated M1-like tumor-associated macrophages polarization. Redox Biol. 76, 103335 (2024)
Article CAS PubMed PubMed Central Google Scholar
L. Yu, Y. Deng, X. Wang et al., Co-targeting JAK1/STAT6/GAS6/TAM signaling improves chemotherapy efficacy in ewing sarcoma. Nat. Commun. 15(1), 5292 (2024)
Article CAS PubMed PubMed Central Google Scholar
N. Nuechterlein, A. Shelbourn, F. Szulzewsky et al., Haploinsufficiency of phosphodiesterase 10A activates PI3K/AKT signaling independent of PTEN to induce an aggressive glioma phenotype. Genes Dev. 38(5–6), 273–288 (2024)
Article CAS PubMed PubMed Central Google Scholar
L. Liu, J. Wang, Y. Wang et al., Blocking the MIF-CD74 axis augments radiotherapy efficacy for brain metastasis in NSCLC via synergistically promoting microglia M1 polarization. J. Exp. Clin. Cancer Res. 43(1), 128 (2024)
Article PubMed PubMed Central Google Scholar
F. Li, K.M. Bondra, H. Wang et al., Dual Inhibition of MAPK and TORC1 signaling retards development of radiation resistance in pediatric BRAFV600E glioma models. Neuro Oncol. 2025
J. Hu, F. Meng, L. Lv et al., GPR37-enhanced ubiquitination of ATP1A1 inhibits tumor progression and radiation resistance in esophageal squamous cell carcinoma. Cell. Death Dis. 15(12), 933 (2024)
Comments (0)