Fontana L, Partridge L, Longo VD. Extending healthy life span–from yeast to humans. Science. 2010;328:321–6. https://doi.org/10.1126/science.1172539.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Longo VD, Anderson RM. Nutrition, longevity and disease: from molecular mechanisms to interventions. Cell. 2022;185:1455–70. https://doi.org/10.1016/j.cell.2022.04.002.

Article  CAS  PubMed  PubMed Central  Google Scholar 

McCay CM, Crowell MF, Maynard LA. The effect of retarded growth upon the length of life span and upon the ultimate body size. J Nutr. 1935;10:63–79.

Article  CAS  Google Scholar 

Guarente L, Picard F. Calorie restriction–the SIR2 connection. Cell. 2005;120:473–82. https://doi.org/10.1016/j.cell.2005.01.029.

Article  CAS  PubMed  Google Scholar 

Heilbronn LK, Ravussin E. Calorie restriction and aging: review of the literature and implications for studies in humans. Am J Clin Nutr. 2003;78:361–9. https://doi.org/10.1093/ajcn/78.3.361.

Article  CAS  PubMed  Google Scholar 

Most J, Tosti V, Redman LM, Fontana L. Calorie restriction in humans: an update. Ageing Res Rev. 2017;39:36–45. https://doi.org/10.1016/j.arr.2016.08.005.

Article  PubMed  Google Scholar 

Partridge L, Piper MD, Mair W. Dietary restriction in Drosophila. Mech Ageing Dev. 2005;126:938–50. https://doi.org/10.1016/j.mad.2005.03.023.

Article  CAS  PubMed  Google Scholar 

Lin SJ, et al. Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration. Nature. 2002;418:344–8. https://doi.org/10.1038/nature00829.

Article  CAS  PubMed  Google Scholar 

Smith DL Jr, McClure JM, Matecic M, Smith JS. Calorie restriction extends the chronological lifespan of Saccharomyces cerevisiae independently of the Sirtuins. Aging Cell. 2007;6:649–62. https://doi.org/10.1111/j.1474-9726.2007.00326.x.

Article  CAS  PubMed  Google Scholar 

Panowski SH, Wolff S, Aguilaniu H, Durieux J, Dillin A. PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans. Nature. 2007;447:550–5.

Article  CAS  PubMed  Google Scholar 

Klass MR. Aging in the nematode Caenorhabditis elegans: major biological and environmental factors influencing life span. Mech Ageing Dev. 1977;6:413–29. https://doi.org/10.1016/0047-6374(77)90043-4.

Article  CAS  PubMed  Google Scholar 

Lakowski B, Hekimi S. The genetics of caloric restriction in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 1998;95:13091–6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Matai L, et al. Dietary restriction improves proteostasis and increases life span through endoplasmic reticulum hormesis. Proc Natl Acad Sci U S A. 2019;116:17383–92. https://doi.org/10.1073/pnas.1900055116.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mair W, Goymer P, Pletcher SD, Partridge L. Demography of dietary restriction and death in Drosophila. Science. 2003;301:1731–3. https://doi.org/10.1126/science.1086016.

Article  CAS  PubMed  Google Scholar 

Chapman T, Partridge L. Female fitness in Drosophila melanogaster: an interaction between the effect of nutrition and of encounter rate with males. Proc Biol Sci. 1996;263:755–9. https://doi.org/10.1098/rspb.1996.0113.

Article  CAS  PubMed  Google Scholar 

Bross TG, Rogina B, Helfand SL. Behavioral, physical, and demographic changes in Drosophila populations through dietary restriction. Aging Cell. 2005;4:309–17. https://doi.org/10.1111/j.1474-9726.2005.00181.x.

Article  CAS  PubMed  Google Scholar 

Tu MP, Tatar M. Juvenile diet restriction and the aging and reproduction of adult Drosophila melanogaster. Aging Cell. 2003;2:327–33.

Article  CAS  PubMed  Google Scholar 

Weindruch R, Walford RL, Fligiel S, Guthrie D. The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake. J Nutr. 1986;116:641–54. https://doi.org/10.1093/jn/116.4.641.

Article  CAS  PubMed  Google Scholar 

Stuchlikova E, Juricova-Horakova M, Deyl Z. New aspects of the dietary effect of life prolongation in rodents. What is the role of obesity in aging? Exp Gerontol. 1975;10:141–4. https://doi.org/10.1016/0531-5565(75)90043-1.

Article  CAS  PubMed  Google Scholar 

Turturro A, et al. Growth curves and survival characteristics of the animals used in the biomarkers of aging program. J Gerontol A Biol Sci Med Sci. 1999;54:B492-501. https://doi.org/10.1093/gerona/54.11.b492.

Article  CAS  PubMed  Google Scholar 

Weiss EP, Fontana L. Caloric restriction: powerful protection for the aging heart and vasculature. Am J Physiol Heart Circ Physiol. 2011;301:H1205-1219. https://doi.org/10.1152/ajpheart.00685.2011.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wei L, Tao Q, Yao M, Zhao Z, Ge S. Caloric restriction can ameliorate postoperative cognitive dysfunction by upregulating the expression of Sirt1, MeCP2 and BDNF in the hippocampal CA1 region of aged C57BL/6 mice. Brain Sci. 2023. https://doi.org/10.3390/brainsci13030462.

Article  PubMed  PubMed Central  Google Scholar 

Hursting SD, Lavigne JA, Berrigan D, Perkins SN, Barrett JC. Calorie restriction, aging, and cancer prevention: mechanisms of action and applicability to humans. Annu Rev Med. 2003;54:131–52. https://doi.org/10.1146/annurev.med.54.101601.152156.

Article  CAS  PubMed  Google Scholar 

Guo Z, et al. Dietary restriction reduces atherosclerosis and oxidative stress in the aorta of apolipoprotein E-deficient mice. Mech Ageing Dev. 2002;123:1121–31. https://doi.org/10.1016/s0047-6374(02)00008-8.

Article  CAS  PubMed  Google Scholar 

Patel NV, et al. Caloric restriction attenuates Abeta-deposition in Alzheimer transgenic models. Neurobiol Aging. 2005;26:995–1000. https://doi.org/10.1016/j.neurobiolaging.2004.09.014.

Article  CAS  PubMed  Google Scholar 

Wang J, et al. Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer’s disease. FASEB J. 2005;19:659–61. https://doi.org/10.1096/fj.04-3182fje.

Article  CAS  PubMed  Google Scholar 

Halagappa VK, et al. Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer’s disease. Neurobiol Dis. 2007;26:212–20. https://doi.org/10.1016/j.nbd.2006.12.019.

Article  CAS  PubMed  Google Scholar 

Colman RJ, et al. Caloric restriction delays disease onset and mortality in rhesus monkeys. Science. 2009;325:201–4. https://doi.org/10.1126/science.1173635.

Article  CAS  PubMed  PubMed Central  Google Scholar