Alkalaeva E.Z., Pisarev A.V., Frolova L.Y., Kisselev L.L., Pestova T.V. 2006. In vitro reconstitution of eukaryotic translation reveals cooperativity between release factors eRF1 and eRF3. Cell. 125, 1125–1136.
Hellen C.U.T. 2018. Translation termination and ribosome recycling in eukaryotes. Cold Spring Harbor Persp. Biol. 10, I. 10. 1–18.
Egorova T., Biziaev N., Shuvalov A., Sokolova E., Mukba S., Evmenov K., Zotova M., Kushchenko A., Shuvalova E., Alkalaeva E. 2021. eIF3j facilitates loading of release factors into the ribosome. Nucleic Acids Res. 49, 11181–11196.
CAS PubMed PubMed Central Google Scholar
Ivanov A., Mikhailova T., Eliseev B., Yeramala L., Sokolova E., Susorov D., Shuvalov A., Schaffitzel C., Alkalaeva E. 2016. PABP enhances release factor recruitment and stop codon recognition during translation termination. Nucleic Acids Res. 44, 7766–7776.
CAS PubMed PubMed Central Google Scholar
Biziaev N., Shuvalov A., Salman A., Egorova T., Shuvalova E., Alkalaeva E. 2024. The impact of mRNA poly(A) tail length on eukaryotic translation stages. Nucleic Acids Res. 52, 7792–7808.
CAS PubMed PubMed Central Google Scholar
Wu C., Roy B., He F., Yan K., Jacobson A. 2020. Poly(A)-binding protein regulates the efficiency of translation termination. Cell Rep. 33, 108399.
CAS PubMed PubMed Central Google Scholar
Ivanov P.V., Gehring N.H., Kunz J.B., Hentze M.W., Kulozik A.E. 2008. Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways. EMBO J. 27, 736–747.
CAS PubMed PubMed Central Google Scholar
Cosson B., Berkova N., Couturier A., Chabelskaya S., Philippe M., Zhouravleva G. 2002. Poly(A)-binding protein and eRF3 are associated in vivo in human and Xenopus cells. Biol. Cell. 94, 205–216.
Hoshino S., Imai M., Kobayashi T., Uchida N., Katada T. 1999. The eukaryotic polypeptide chain releasing factor (eRF3/GSPT) carrying the translation termination signal to the 3′-poly(A) tail of mRNA. J. Biol. Chem. 274, 16677–16680.
Uchida N., Hoshino S., Imataka H., Sonenberg N., Katada T. 2002. A novel role of the mammalian GSPT/eRF3 associating with poly(A)-binding protein in cap/poly(A)-dependent translation. J. Biol. Chem. 277, 50286–50292.
Biziaev N.S., Egorova T.V., Alkalaeva E.Z. 2022. Dynamics of eukaryotic mRNA structure during translation. Mol. Biol. (Moscow). 56, 382–394. https://doi.org/10.1134/S0026893322030037
Lima S.A., Chipman L.B., Nicholson A.L., Chen Y.H., Yee B.A., Yeo G.W., Coller J., Pasquinelli A.E. 2017. Short poly(A) tails are a conserved feature of highly expressed genes. Nat. Struct. Mol. Biol. 24, 1057–1063.
CAS PubMed PubMed Central Google Scholar
Beier H., Grimm M. 2001. Misreading of termination codons in eukaryotes by natural nonsense suppressor tRNAs. Nucleic Acids Res. 29, 4767–4782.
CAS PubMed PubMed Central Google Scholar
Bertram G., Innes S., Minella O., Richardson J., Stansfield I. 2001. Endless possibilities: Translation termination and stop codon recognition. Microbiology. 147, 255–269.
Roy B., Leszyk J.D., Mangus D.A., Jacobson A. 2015. Nonsense suppression by near-cognate tRNAs employs alternative base pairing at codon positions 1 and 3. Proc. Natl. Acad. Sci. U. S. A. 112, 3038–3043.
CAS PubMed PubMed Central Google Scholar
Vallabhaneni H., Fan-Minogue H., Bedwell D.M., Farabaugh P.J. 2009. Connection between stop codon reassignment and frequent use of shifty stop frameshifting. RNA. 15, 889–897.
CAS PubMed PubMed Central Google Scholar
Kurian L., Palanimurugan R., Gödderz D., Dohmen R.J. 2011. Polyamine sensing by nascent ornithine decarboxylase antizyme stimulates decoding of its mRNA. Nature. 477, 490–494.
Amrani N., Sachs M.S., Jacobson A. 2006. Early nonsense: mRNA decay solves a translational problem. Nat. Rev. Mol. Cell. Biol. 7, 415–425.
Celik A., Kervestin S., Jacobson A. 2015. NMD: At the crossroads between translation termination and ribosome recycling. Biochimie. 114, 2–9.
Raimondeau E., Bufton J.C., Schaffitzel C. 2018. New insights into the interplay between the translation machinery and nonsense-mediated mRNA decay factors. Biochem. Soc. Trans. 46, 503–512.
CAS PubMed PubMed Central Google Scholar
Embree C.M., Abu-Alhasan R., Singh G. 2022. Features and factors that dictate if terminating ribosomes cause or counteract nonsense-mediated mRNA decay. J. Biol. Chem. 298, 102592.
CAS PubMed PubMed Central Google Scholar
Sokolova E.E., Vlasov P.K., Egorova T.V., Shuvalov A.V., Alkalaeva E.Z. 2020. The Influence of A/G Composition of 3’ Stop Codon Contexts on Translation Termination Efficiency in Eukaryotes. Mol. Biol. (Moscow). 54, 739–748. https://doi.org/10.1134/S0026893320050088
Cridge A.G., Crowe-McAuliffe C., Mathew S.F., Tate W.P. 2018. Eukaryotic translational termination efficiency is influenced by the 3′ nucleotides within the ribosomal mRNA channel. Nucleic Acids Res. 46, 1927–1944.
CAS PubMed PubMed Central Google Scholar
Björnsson A., Mottagui-Tabar S., Isaksson L.A. 1996. Structure of the C-terminal end of the nascent peptide influences translation termination. EMBO J. 15, 1696–1704.
PubMed PubMed Central Google Scholar
Mottagui-Tabar S., Tuite M.F., Isaksson L.A. 1998. The influence of 5’ codon context on translation termination in Saccharomyces cerevisiae. Eur. J. Biochem. 257, 249–254.
Tork S., Hatin I., Rousset J.P., Fabret C. 2004. The major 5′ determinant in stop codon read-through involves two adjacent adenines. Nucleic Acids Res. 32, 415–421.
CAS PubMed PubMed Central Google Scholar
Wangen J.R., Green R. 2020. Stop codon context influences genome-wide stimulation of termination codon readthrough by aminoglycosides. ELife. 9, 1–29.
Dabrowski M., Bukowy-Bieryllo Z., Zietkiewicz E. 2015. Translational readthrough potential of natural termination codons in eucaryotes—the impact of RNA sequence. RNA Biol. 12, 950–958.
PubMed PubMed Central Google Scholar
Cassan M., Rousset J.P. 2001. UAG readthrough in mammalian cells: effect of upstream and downstream stop codon contexts reveal different signals. BMC Mol. Biol. 2, 3.
CAS PubMed PubMed Central Google Scholar
Bonetti B., Fu L., Moon J., Bedwell D.M. 1995. The efficiency of translation termination is determined by a synergistic interplay between upstream and downstream sequences in Saccharomyces cerevisiae. J. Mol. Biol. 251, 334–345.
Loughran G., Chou M.Y., Ivanov I.P., Jungreis I., Kellis M., Kiran A.M., Baranov P.V., Atkins J.F. 2014. Evidence of efficient stop codon readthrough in four mammalian genes. Nucleic Acids Res. 42, 8928–8938.
CAS PubMed PubMed Central Google Scholar
Williams I., Richardson J., Starkey A., Stansfield I. 2004. Genome-wide prediction of stop codon readthrough during translation in the yeast Saccharomyces cerevisiae. Nucleic Acids Res. 32, 6605–6616.
CAS PubMed PubMed Central Google Scholar
Bohlen J., Harbrecht L., Blanco S., Clemm von Hohenberg K., Fenzl K., Kramer G., Bukau B., Teleman A.A. 2020. DENR promotes translation reinitiation via ribosome recycling to drive expression of oncogenes including ATF4. Nat. Commun. 11, 4676.
Young D.J., Meydan S., Guydosh N.R. 2021. 40S ribosome profiling reveals distinct roles for Tma20/Tma22 (MCT-1/DENR) and Tma64 (eIF2D) in 40S subunit recycling. Nat. Commun. 12, 2976.
Young D.J., Guydosh N.R. 2022. Rebirth of the translational machinery: The importance of recycling ribosomes. BioEssays. 44, 2100269.
Kolakada D., Fu R., Biziaev N., Shuvalov A., Lore M., Campbell A.E., Cortázar M.A., Sajek M.P., Hesselberth J.R., Mukherjee N., Alkalaeva E., Coban-Akdemir Z.H., Jagannathan S. 2025. Systematic analysis of nonsense variants uncovers peptide release rate as a novel modifier of nonsense-mediated mRNA decay. Cell Genomics, 100882.
Pierson W.E., Hoffer E.D., Keedy H.E., Simms C.L., Dunham C.M., Zaher H.S. 2016. Uniformity of peptide release is maintained by methylation of release factors. Cell Rep. 17, 11–18.
CAS PubMed PubMed Central Google Scholar
Meydan S., Guydosh N.R. 2020. Disome and trisome profiling reveal genome-wide targets of ribosome quality control. Mol. Cell. 79, 588–602.e6.
Comments (0)