Classic lipid profile and lipoprotein(a) in systemic sclerosis: a systematic review and meta-analysis of case-control studies

Bournia VK, Fragoulis GE, Mitrou P, Mathioudakis K, Tsolakidis A, Konstantonis G, Vourli G, Paraskevis D, Tektonidou MG, Sfikakis PP (2021) All-cause mortality in systemic rheumatic diseases under treatment compared with the general population, 2015–2019. RMD Open 7. https://doi.org/10.1136/rmdopen-2021-001694

Article  Google Scholar 

Bournia VK, Fragoulis GE, Mitrou P, Tsolakidis A, Mathioudakis K, Vassilopoulos D, Tektonidou M, Paraskevis D, Sfikakis PP (2024) Increased prevalence of inflammatory arthritis, systemic lupus erythematosus and systemic sclerosis, during 2020–2023 versus 2016–2019 in a nation-wide cohort study. Rheumatol Int 44:2837–2846. https://doi.org/10.1007/s00296-024-05733-y

Article  PubMed  Google Scholar 

Volkmann ER, Andréasson K, Smith V (2023) Systemic sclerosis. Lancet 401:304–318. https://doi.org/10.1016/s0140-6736(22)01692-0

Article  PubMed  Google Scholar 

Makris A, Panagiotopoulos A, Distler O, Sfikakis PP (2024) Systemic sclerosis sine scleroderma: a time of reappraisal. J Rheumatol 51:1060–1068. https://doi.org/10.3899/jrheum.2023-1113

Article  PubMed  Google Scholar 

Cen X, Feng S, Wei S, Yan L, Sun L (2020) Systemic sclerosis and risk of cardiovascular disease: A PRISMA-compliant systemic review and meta-analysis of cohort studies. Med (Baltim) 99:e23009. https://doi.org/10.1097/md.0000000000023009

Article  Google Scholar 

Kaul A, Gordon C, Crow MK, Touma Z, Urowitz MB, van Vollenhoven R, Ruiz-Irastorza G, Hughes G (2016) Systemic lupus erythematosus. Nat Rev Dis Primers 2:16039. https://doi.org/10.1038/nrdp.2016.39

Article  PubMed  Google Scholar 

Urowitz MB, Gladman D, Ibañez D, Fortin P, Sanchez-Guerrero J, Bae S, Clarke A, Bernatsky S, Gordon C, Hanly J, Wallace D, Isenberg D, Ginzler E, Merrill J, Alarcon G, Steinsson K, Petri M, Dooley MA, Bruce I, Manzi S, Khamashta M, Ramsey-Goldman R, Zoma A, Sturfelt G, Nived O, Maddison P, Font J, van Vollenhoven R, Aranow C, Kalunian K, Stoll T, Buyon J (2007) Clinical manifestations and coronary artery disease risk factors at diagnosis of systemic lupus erythematosus: data from an international inception cohort. Lupus 16:731–735. https://doi.org/10.1177/0961203307081113

Article  PubMed  CAS  Google Scholar 

Wigren M, Nilsson J, Kaplan MJ (2015) Pathogenic immunity in systemic lupus erythematosus and atherosclerosis: common mechanisms and possible targets for intervention. J Intern Med 278:494–506. https://doi.org/10.1111/joim.12357

Article  PubMed  PubMed Central  CAS  Google Scholar 

Borba EF, Bonfá E (1997) Dyslipoproteinemias in systemic lupus erythematosus: influence of disease, activity, and anticardiolipin antibodies. Lupus 6:533–539. https://doi.org/10.1177/096120339700600610

Article  PubMed  CAS  Google Scholar 

Dessie G, Tadesse Y, Demelash B, Genet S (2020) Assessment of serum lipid profiles and High-sensitivity C-reactive protein among patients suffering from rheumatoid arthritis at Tikur Anbessa specialized hospital, addis ababa, ethiopia: A Cross-Sectional study. Open Access Rheumatol 12:223–232. https://doi.org/10.2147/oarrr.S264466

Article  PubMed  PubMed Central  CAS  Google Scholar 

Choy E, Sattar N (2009) Interpreting lipid levels in the context of high-grade inflammatory States with a focus on rheumatoid arthritis: a challenge to conventional cardiovascular risk actions. Ann Rheum Dis 68:460–469. https://doi.org/10.1136/ard.2008.101964

Article  PubMed  CAS  Google Scholar 

Papazoglou N, Sfikakis PP, Tektonidou MG (2024) Atherosclerotic plaque progression and incident cardiovascular events in a 10-year prospective study of patients with systemic lupus erythematosus: the impact of persistent cardiovascular risk factor target attainment and sustained DORIS remission. Arthritis Rheumatol. https://doi.org/10.1002/art.43097

Article  Google Scholar 

Drosos GC, Konstantonis G, Sfikakis PP, Tektonidou MG (2023) Cardiovascular risk assessment in patients with antiphospholipid syndrome: a cross-sectional performance analysis of nine clinical risk prediction tools. RMD Open. https://doi.org/10.1136/rmdopen-2023-003601

Article  PubMed  PubMed Central  Google Scholar 

Karpouzas GA, Papotti B, Ormseth SR, Palumbo M, Hernandez E, Adorni MP, Zimetti F, Ronda N (2024) Changes in serum cholesterol loading capacity are linked to coronary atherosclerosis progression in rheumatoid arthritis. RMD Open. https://doi.org/10.1136/rmdopen-2024-004991

Article  PubMed  PubMed Central  Google Scholar 

Au K, Singh MK, Bodukam V, Bae S, Maranian P, Ogawa R, Spiegel B, McMahon M, Hahn B, Khanna D (2011) Atherosclerosis in systemic sclerosis: a systematic review and meta-analysis. Arthritis Rheum 63:2078–2090. https://doi.org/10.1002/art.30380

Article  PubMed  PubMed Central  Google Scholar 

Bećarević M, Singh S, Majkić-Singh N (2007) Lipoprotein (a) and Apolipoprotein (a) in primary antiphospholipid syndrome. Clin Biochem 40:317–320. https://doi.org/10.1016/j.clinbiochem.2006.11.018

Article  PubMed  CAS  Google Scholar 

Wang J, Hu B, Kong L, Cai H, Zhang C (2008) Native, oxidized lipoprotein(a) and lipoprotein(a) immune complex in patients with active and inactive rheumatoid arthritis: plasma concentrations and relationship to inflammation. Clin Chim Acta 390:67–71. https://doi.org/10.1016/j.cca.2007.12.015

Article  PubMed  CAS  Google Scholar 

Ames PR, Lupoli S, Alves J, Atsumi T, Edwards C, Iannaccone L, Khamashta MA, Hughes GR, Brancaccio V (1997) The coagulation/fibrinolysis balance in systemic sclerosis: evidence for a haematological stress syndrome. Br J Rheumatol 36:1045–1050. https://doi.org/10.1093/rheumatology/36.10.1045

Article  PubMed  CAS  Google Scholar 

Missala I, Kassner U, Steinhagen-Thiessen E (2012) A systematic literature review of the association of lipoprotein(a) and autoimmune diseases and atherosclerosis. Int J Rheumatol 2012:480784. https://doi.org/10.1155/2012/480784

Article  PubMed  PubMed Central  CAS  Google Scholar 

Gogulska Z, Smolenska Z, Turyn J, Mika A, Zdrojewski Z (2021) Lipid alterations in systemic sclerosis. Front Mol Biosci 8:761721. https://doi.org/10.3389/fmolb.2021.761721

Article  PubMed  PubMed Central  CAS  Google Scholar 

Scipione CA, Koschinsky ML, Boffa MB (2018) Lipoprotein(a) in clinical practice: new perspectives from basic and translational science. Crit Rev Clin Lab Sci 55:33–54. https://doi.org/10.1080/10408363.2017.1415866

Article  PubMed  CAS  Google Scholar 

Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hróbjartsson A, Lalu MM, Li T, Loder EW, Mayo-Wilson E, McDonald S, McGuinness LA, Stewart LA, Thomas J, Tricco AC, Welch VA, Whiting P, Moher D (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 372:n71. https://doi.org/10.1136/bmj.n71

Article  PubMed  PubMed Central  Google Scholar 

McGrath S, Zhao X, Steele R, Thombs BD, Benedetti A (2020) Estimating the sample mean and standard deviation from commonly reported quantiles in meta-analysis. Stat Methods Med Res 29:2520–2537. https://doi.org/10.1177/0962280219889080

Article  PubMed  PubMed Central  Google Scholar 

Bruckdorfer KR, Hillary JB, Bunce T, Vancheeswaran R, Black CM (1995) Increased susceptibility to oxidation of low-density lipoproteins isolated from patients with systemic sclerosis. Arthritis Rheum 38:1060–1067. https://doi.org/10.1002/art.1780380807

Article  PubMed  CAS  Google Scholar 

Ho M, Veale D, Eastmond C, Nuki G, Belch J (2000) Macrovascular disease and systemic sclerosis. Ann Rheum Dis 59:39–43. https://doi.org/10.1136/ard.59.1.39

Article  PubMed  PubMed Central  CAS  Google Scholar 

Cerinic MM, Valentini G, Sorano GG, D’Angelo S, Cuomo G, Fenu L, Generini S, Cinotti S, Morfini M, Pignone A, Guiducci S, Del Rosso A, Kalfin R, Das D, Marongiu F (2003) Blood coagulation, fibrinolysis, and markers of endothelial dysfunction in systemic sclerosis. Semin Arthritis Rheum 32:285–295. https://doi.org/10.1053/sarh.2002.50011

Article  PubMed  CAS  Google Scholar 

Zakopoulos NA, Kotsis VT, Gialafos EJ, Papamichael CM, Pitiriga V, Mitsibounas DN, Mavrikakis ME (2003) Systemic sclerosis is not associated with clinical or ambulatory blood pressure. Clin Exp Rheumatol 21:199–204

PubMed  CAS 

Comments (0)

No login
gif