Sahoo D, Bandaru R, Samal SK, Naik R, Kumar P, Kesharwani P, et al. Oral drug delivery of nanomedicine. In: Theory and Applications of Nonparenteral Nanomedicines. 2021. Academic Press. p. 181–207. https://doi.org/10.1016/B978-0-12-820466-5.00009-0

Kawabata Y, Wada K, Nakatani M, Yamada S, Onoue S. Formulation design for poorly water-soluble drugs based on biopharmaceutics classification system: Basic approaches and practical applications. Int J Pharm. 2011;420(1–2):1–10. https://doi.org/10.1016/j.ijpharm.2011.08.032.

Article  CAS  PubMed  Google Scholar 

Miyake M, Oka Y, Minami T, Toguchi H, Odomi M, Ogawara K, et al. Combinatorial use of sodium laurate with taurine or l-glutamine enhances colonic absorption of rebamipide, poorly absorbable antiulcer drug, without any serious histopathological mucosal damages. J Pharm Sci. 2003;92:911–21. https://doi.org/10.1002/jps.10362.

Article  CAS  PubMed  Google Scholar 

Koga K, Takarada N, Takada K. Nano-sized water-in-oil-in-water emulsion enhances intestinal absorption of calcein, a high solubility and low permeability compound. Eur J Pharm Biopharm. 2010;74(2):223–32. https://doi.org/10.1016/j.ejpb.2009.09.004.

Article  CAS  PubMed  Google Scholar 

Shima M, Tanaka M, Fujii T, Egawa K, Kimura Y, Adachi S, et al. Oral administration of insulin included in fine W/O/W emulsions to rats. Food Hydrocolloids. 2006;20(4):523–31. https://doi.org/10.1016/j.foodhyd.2005.05.002.

Article  CAS  Google Scholar 

Lutz R, Aserin A, Wicker L, Garti N. Release of electrolytes from W/O/W double emulsions stabilized by a soluble complex of modified pectin and whey protein isolate. Colloids Surf B Biointerfaces. 2009;74(1):178–85. https://doi.org/10.1016/j.colsurfb.2009.07.014.

Article  CAS  PubMed  Google Scholar 

Verma NK, Mishra JN. Multiple emulsions and its stabilization: a review. Int J Chem Stud. 2023;3(3):12–6. http://www.researchgate.net/publication/372400988. Accessed 7 July 2025.

Padole A, Bodhankar M. Self double emulsifying drug delivery system (SDEDDS): a review. J Drug Deliv Ther. 2012;2(6):124–7. https://doi.org/10.22270/jddt.v2i6.336.

Article  CAS  Google Scholar 

Khan AY, Talegaonkar S, Iqbal Z, Ahmed FJ, Khar RK. Multiple emulsions: an overview. Curr Drug Deliv. 2006;3(4):429–43. https://doi.org/10.2174/156720106778559056.

Article  CAS  PubMed  Google Scholar 

Tang B, Cheng G, Gu JC, Xu CH. Development of solid self-emulsifying drug delivery systems: preparation techniques and dosage forms. Drug Discov Today. 2008;13:606–12. https://doi.org/10.1016/j.drudis.2008.04.006.

Article  CAS  PubMed  Google Scholar 

Jaimini M, Rana AC, Tanwar YS. Formulation and Evaluation of Famotidine Floating Tablets. Curr Drug Deliv. 2007;4(1):51–5. https://doi.org/10.2174/156720107779314730.

Article  CAS  PubMed  Google Scholar 

Mokhtar M, Gosselin PM, Lacasse F, Hildgen P. Design of PEG-grafted-PLA nanoparticles as oral permeability enhancer for P-gp substrate drug model Famotidine. J Microencapsul. 2017;34(3):269–82. https://doi.org/10.1080/02652048.2017.1290155.

Article  CAS  Google Scholar 

Satishbabu BK, Sandeep VR, Ravi RB, Shrutinag R. Formulation and evaluation of floating drug delivery system of famotidine. Indian J Pharm Sci. 2010;72(6):738–44. https://doi.org/10.4103/0250-474x.84583.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhu X, Qi X, Wu Z, Zhang Z, Xing J, Li X. Preparation of multiple-unit floating-bioadhesive cooperative minitablets for improving the oral bioavailability of famotidine in rats. Drug Deliv. 2014;21(6):459–66. https://doi.org/10.3109/10717544.2013.879626.

Article  CAS  PubMed  Google Scholar 

Mishra V, Kaur R. Formulation and pharmacokinetic study of famotidine loaded floating microballoons. Int J Pharm Pharm Sci. 2012;4:511–5.

CAS  Google Scholar 

Jha SK, Karki R, Puttegowda VD, Harinarayana D. In vitro intestinal permeability studies and pharmacokinetic evaluation of famotidine microemulsion for oral delivery. ISRN Pharm. 2014;3:1–7. https://doi.org/10.1155/2014/452051.

Article  Google Scholar 

Khan R, Irchhaiya R. In vitro and in-vivo evaluation of niosomal formulation of famotidine. Int J Pharm Pharm Sci. 2020;12(3):15–22. https://doi.org/10.22159/ijpps.2020v12i3.36210.

Article  CAS  Google Scholar 

Alagusundaram M, Chetty CM, Dhachinamoorthi D. Development and evaluation of novel trans-buccoadhesive films of famotidine. J Adv Pharm Tech Res. 2011;2:17–23. https://doi.org/10.4103/2231-4040.79800.

Article  CAS  Google Scholar 

El-Dakroury WA, Zewail MB, Elsabahy M, Shabana ME, Asaad GF. Famotidine-loaded solid self-nanoemulsifying drug delivery system demonstrates exceptional efficiency in amelioration of peptic ulcer. Int J Pharm. 2022;611:121303. https://doi.org/10.1016/j.ijpharm.2021.121303.

Article  CAS  PubMed  Google Scholar 

Mokale VJ, Patil HI, Patil AP, Shirude PR, Naik JB. Formulation and optimization of famotidine proniosomes: an in vitro and ex vivo study. J Exp Nanosci. 2016;11(2):97–110. https://doi.org/10.1080/17458080.2015.1030711.

Article  CAS  Google Scholar 

Ramachandran S, Shaheedha SM, Thirumurugan G, Dhanaraju MD. Floating controlled drug delivery system of famotidine loaded hollow microspheres (microballoons) in the stomach. Curr Drug Deliv. 2010;7(1):93–7. https://doi.org/10.2174/156720110790396436.

Article  CAS  PubMed  Google Scholar 

Chordiya MA, Gangurde HH, Senthilkumaran K, Kothari LP. Formulation development and in vitro evaluation of gastroretentive hollow microspheres of famotidine. Int J Pharm Investig. 2011;1(2):105–11. https://doi.org/10.4103/2230-973x.82423.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kumar R, Gautam PK, Chandra A. Formulation and evaluation of famotidine microballoons with enhanced anti-ulcer activity. Int J App Pharm. 2018;10(3):131–40. https://doi.org/10.22159/ijap.2018v10i3.25306.

Article  CAS  Google Scholar 

Qi X, Wang L, Zhu J, Hu Z, Zhang J. Self-double-emulsifying drug delivery system (SDEDDS): A new way for oral delivery of drugs with high solubility & low permeability. Int J Pharm. 2011;409:245–51. https://doi.org/10.1016/j.ijpharm.2011.02.047.

Article  CAS  PubMed  Google Scholar 

Zhang L, Zhang Q, Zhou P, Zhang L, Liu Q, Zhang Z. Enhanced absorption of stachydrine using a self-double-emulsifying drug delivery system (SDEDDS): In vitro and in-vivo studies. Life Sci J. 2013;10(4):895–9.

Google Scholar 

Hu C, Wang Q, Zhao G, Yao W, Xia Q. Improved oral absorption of (−)-epigallocatechin-3-gallate via self-double-emulsifying solid formulation. Eur J Lipid Sci Technol. 2015;117:1–10. https://doi.org/10.1002/ejlt.201500316.

Article  CAS  Google Scholar 

Qiang Wang Q, Lu X, Chen L, Li Z, Yang Y. Enhanced oral bioavailability of quercetin by a new nonaqueous self-double-emulsifying drug delivery system. Eur J Lipid Sci Tech. 2016;119:1600167. https://doi.org/10.1002/ejlt.201600167.

Article  CAS  Google Scholar 

Bhattacharjee A, Verma S, Verma PRP, Singh SK, Chakraborty A. Fabrication of liquid and solid self-double emulsifying drug delivery system of atenolol by response surface methodology. J Drug Deliv Sci Technol. 2018;17:30083–7. https://doi.org/10.1016/j.jddst.2017.06.014.

Article  CAS  Google Scholar 

Wang X, Jiang S, Wang X, Liao J, Yin Z. Preparation and evaluation of nattokinase-loaded self-double-emulsifying drug delivery system. Asian J Pharm Sci. 2015;10:386–95. https://doi.org/10.1016/j.ajps.2015.04.005.

Article  Google Scholar 

Kolhe SM, Patil AT, Bawane PP, Gawad JB. Development and evaluation of solid self-double emulsifying drug delivery system (SSDEDDS): a novel approach to enhance bioavailability of BCS class III drugs. J Pharm Res. 2016;10(6):403–9. https://www.researchgate.net/publication/304351053. Accessed 7 July 2025.

Poharkar S, Jannawar A, Rathod M. Development and evaluation of self-emulsifying drug delivery system. IOSR J Pharm. 2019;9(5):66–92. https://www.iosrphr.org/papers/vol9-issue5/Series-1/I0905016693.pdf. Accessed 7 July 2025.

Tian Y, Mao X, Sun R, Zhang M, Xia Q. Enhanced oral bioavailability of oligomeric proanthocyanidins by a self-double-emulsifying drug delivery system. Food Sci Nutr. 2020;8:3814–25. https://doi.org/10.1002/fsn3.1673.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lv LZ, Tong CQ, Lv Q, Tang XJ, Li LM, Fang QX, et al. Enhanced absorption of hydroxysafflor yellow A using a self-double-emulsifying drug delivery system: in vitro and in vivo studies. Int J Nanomedicine. 2012;7:4099–107. https://doi.org/10.2147/ijn.s33398.

Article  CAS