Hanahan D (2022) Hallmarks of cancer: new dimensions. Cancer Discov 12:31–46. https://doi.org/10.1158/2159-8290.CD-21-1059
Article CAS PubMed Google Scholar
Grivennikov SI, Greten FR, Karin M (2010) Immunity, inflammation, and cancer. Cell 140:883–899. https://doi.org/10.1016/j.cell.2010.01.025
Article CAS PubMed PubMed Central Google Scholar
Bui JD, Schreiber RD (2007) Cancer immunosurveillance, immunoediting and inflammation: independent or interdependent processes? Curr Opin Immunol 19:203–208. https://doi.org/10.1016/J.COI.2007.02.001
Article CAS PubMed Google Scholar
Galdiero MR, Bonavita E, Barajon I et al (2013) Tumor associated macrophages and neutrophils in cancer. Immunobiology 218:1402–1410. https://doi.org/10.1016/J.IMBIO.2013.06.003
Article CAS PubMed Google Scholar
Templeton AJ, McNamara MG, Šeruga B et al (2014) Prognostic role of neutrophil-to-lymphocyte ratio in solid tumors: a systematic review and meta-analysis. J Natl Cancer Inst 106. https://doi.org/10.1093/jnci/dju124
Heng DYC, Xie W, Regan MM et al (2009) Prognostic factors for overall survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-targeted agents: results from a large, multicenter study. J Clin Oncol 27:5794–5799. https://doi.org/10.1200/JCO.2008.21.4809
Article CAS PubMed Google Scholar
Motzer RJ, Bacik J, Murphy BA et al (2002) Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma. J Clin Oncol 20:289–296. https://doi.org/10.1200/JCO.20.1.289
Article CAS PubMed Google Scholar
Saal J, Bald T, Hölzel M et al (2022) In the phase III IMmotion151 trial of metastatic renal cell carcinoma the easy-to-implement modified Glasgow prognostic score predicts outcome more accurately than the IMDC score. Ann Oncol 33:982–984. https://doi.org/10.1016/j.annonc.2022.06.003
Article CAS PubMed Google Scholar
Motzer RJ, Tannir NM, McDermott DF et al (2018) Nivolumab plus ipilimumab versus sunitinib in advanced renal-cell carcinoma. N Engl J Med 378:1277–1290. https://doi.org/10.1056/nejmoa1712126
Article CAS PubMed PubMed Central Google Scholar
Motzer RJ, Penkov K, Haanen J et al (2019) Avelumab plus axitinib versus sunitinib for advanced renal-cell carcinoma. N Engl J Med. https://doi.org/10.1056/NEJMoa1816047
Article PubMed PubMed Central Google Scholar
Rini BI, Plimack ER, Stus V et al (2019) Pembrolizumab plus axitinib versus sunitinib for advanced renal-cell carcinoma. N Engl J Med 380:1116–1127. https://doi.org/10.1056/nejmoa1816714
Article CAS PubMed Google Scholar
Xia L, Oyang L, Lin J et al (2021) The cancer metabolic reprogramming and immune response. Mol Cancer 201(20):1–21. https://doi.org/10.1186/S12943-021-01316-8
Janssen LME, Ramsay EE, Logsdon CD, Overwijk WW (2017) The immune system in cancer metastasis: friend or foe? J Immunother Cancer 5:79–79. https://doi.org/10.1186/S40425-017-0283-9
Article PubMed PubMed Central Google Scholar
Beypınar I, Sözel Y, Önder AH (2023) Assessing the prognostic value of IMDC risk score for nivolumab-treated patients with renal cancer and malignant melanoma. Cancer Biomark Preprint 1–11. https://doi.org/10.3233/CBM-230159
Sasaki A, Nakamura Y, Mishima S et al (2019) Predictive factors for hyperprogressive disease during nivolumab as anti-PD1 treatment in patients with advanced gastric cancer. Gastric Cancer
Blank C, Mackensen A (2007) Contribution of the PD-L1/PD-1 pathway to T-cell exhaustion: an update on implications for chronic infections and tumor evasion. Cancer Immunol Immunother CII 56:739–745. https://doi.org/10.1007/S00262-006-0272-1
Zhang Z, Li Y, Yan X et al (2019) Pretreatment lactate dehydrogenase may predict outcome of advanced non small-cell lung cancer patients treated with immune checkpoint inhibitors: a meta-analysis. Cancer Med 8:1467–1473. https://doi.org/10.1002/CAM4.2024
Article CAS PubMed PubMed Central Google Scholar
Arkenau HT, Olmos D, Ang JE et al (2008) Clinical outcome and prognostic factors for patients treated within the context of a phase I study: the Royal Marsden Hospital experience. Br J Cancer 98:1029–1033. https://doi.org/10.1038/SJ.BJC.6604218
Article CAS PubMed PubMed Central Google Scholar
Garrido-Laguna I, Janku F, Vaklavas C et al (2012) Validation of the Royal Marsden Hospital prognostic score in patients treated in the Phase I clinical trials program at the MD Anderson Cancer Center. Cancer 118:1422–1428. https://doi.org/10.1002/CNCR.26413
Wyld L, Gutteridge E, Pinder SE et al (2003) Prognostic factors for patients with hepatic metastases from breast cancer. Br J Cancer 89:284–290. https://doi.org/10.1038/SJ.BJC.6601038
Article CAS PubMed PubMed Central Google Scholar
Ye LC, Liu TS, Ren L et al (2013) Randomized controlled trial of cetuximab plus chemotherapy for patients with KRAS wild-type unresectable colorectal liver-limited metastases. J Clin Oncol Off J Am Soc Clin Oncol 31:1931–1938. https://doi.org/10.1200/JCO.2012.44.8308
Rosenberg JE, Hoffman-Censits J, Powles T et al (2016) Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial. The Lancet 387:1909–1920. https://doi.org/10.1016/S0140-6736(16)00561-4
New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). https://pubmed.ncbi.nlm.nih.gov/19097774/. Accessed 31 Jan 2025
van Dijk N, Funt SA, Blank CU et al (2019) The cancer immunogram as a framework for personalized immunotherapy in urothelial cancer. Eur Urol 75:435–444. https://doi.org/10.1016/J.EURURO.2018.09.022
Tanizaki J, Haratani K, Hayashi H et al (2018) Peripheral blood biomarkers associated with clinical outcome in non-small cell lung cancer patients treated with nivolumab. J Thorac Oncol Off Publ Int Assoc Study Lung Cancer 13:97–105. https://doi.org/10.1016/J.JTHO.2017.10.030
Simonaggio A, Elaidi R, Fournier L et al (2020) Variation in neutrophil to lymphocyte ratio (NLR) as predictor of outcomes in metastatic renal cell carcinoma (mRCC) and non-small cell lung cancer (mNSCLC) patients treated with nivolumab. Cancer Immunol Immunother 69:2513–2522. https://doi.org/10.1007/S00262-020-02637-1/METRICS
Article CAS PubMed PubMed Central Google Scholar
Rosner S, Kwong E, Shoushtari AN et al (2018) Peripheral blood clinical laboratory variables associated with outcomes following combination nivolumab and ipilimumab immunotherapy in melanoma. Cancer Med 7:690–697. https://doi.org/10.1002/CAM4.1356
Article CAS PubMed PubMed Central Google Scholar
Brown JT, Liu Y, Shabto JM et al (2021) Original research: Modified Glasgow Prognostic Score associated with survival in metastatic renal cell carcinoma treated with immune checkpoint inhibitors. J Immunother Cancer 9:2851–2851. https://doi.org/10.1136/JITC-2021-002851
Rebuzzi SE, Signori A, Banna GL et al (2021) Inflammatory indices and clinical factors in metastatic renal cell carcinoma patients treated with nivolumab: the development of a novel prognostic score (Meet-URO 15 study). Ther Adv Med Oncol 13:17588359211019642. https://doi.org/10.1177/17588359211019642
Article CAS PubMed PubMed Central Google Scholar
Rebuzzi SE, Signori A, Buti S et al (2022) Validation of the Meet-URO score in patients with metastatic renal cell carcinoma receiving first-line nivolumab and ipilimumab in the Italian Expanded Access Program. ESMO Open 7:100634. https://doi.org/10.1016/j.esmoop.2022.100634
Article CAS PubMed PubMed Central Google Scholar
Săftescu S, Șerban N, Volovăț S et al (2021) Predictors of the response to nivolumab immunotherapy in the second or subsequent lines for metastatic non-small cell lung cancers. Exp Ther Med 21:605–605. https://doi.org/10.3892/etm.2021.10037
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