Cao YY, Wu LL, Li XN, Yuan YL, Zhao WW, Qi JX. Molecular mechanisms of AMPA receptor trafficking in the nervous system. Int J Mol Sci 2023, 25: 111.

Article  PubMed  PubMed Central  Google Scholar 

Kamalova A, Nakagawa T. AMPA receptor structure and auxiliary subunits. J Physiol 2021, 599: 453–469.

Article  CAS  PubMed  Google Scholar 

Chang PKY, Verbich D, McKinney RA. AMPA receptors as drug targets in neurological disease—advantages, caveats, and future outlook. Eur J Neurosci 2012, 35: 1908–1916.

Article  PubMed  Google Scholar 

Meldrum BS, Rogawski MA. Molecular targets for antiepileptic drug development. Neurotherapeutics 2007, 4: 18–61.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ornstein PL, Arnold MB, Augenstein NK, Lodge D, Leander JD, Schoepp DD. (3SR, 4aRS, 6RS, 8aRS)-6-[2-(1H-tetrazol-5-yl)ethyl]decahydroisoquinoline-3 - carboxylic acid: A structurally novel, systemically active, competitive AMPA receptor antagonist. J Med Chem 1993, 36: 2046–2048.

Article  CAS  PubMed  Google Scholar 

Faught E. BGG492 (selurampanel), an AMPA/kainate receptor antagonist drug for epilepsy. Expert Opin Investig Drugs 2014, 23: 107–113.

Article  CAS  PubMed  Google Scholar 

Barreca ML, Gitto R, Quartarone S, De Luca L, De Sarro G, Chimirri A. Pharmacophore modeling as an efficient tool in the discovery of novel noncompetitive AMPA receptor antagonists. J Chem Inf Comput Sci 2003, 43: 651–655.

Article  CAS  PubMed  Google Scholar 

Balannik V, Menniti FS, Paternain AV, Lerma J, Stern-Bach Y. Molecular mechanism of AMPA receptor noncompetitive antagonism. Neuron 2005, 48: 279–288.

Article  CAS  PubMed  Google Scholar 

Gao M, Kong D, Clearfield A, Zheng QH. Synthesis of carbon-11 and fluorine-18 labeled N-acetyl-1-aryl-6, 7-dimethoxy-1, 2, 3, 4-tetrahydroisoquinoline derivatives as new potential PET AMPA receptor ligands. Bioorg Med Chem Lett 2006, 16: 2229–2233.

Article  CAS  PubMed  Google Scholar 

Lee HG, Milner PJ, Placzek MS, Buchwald SL, Hooker JM. Virtually instantaneous, room-temperature [(11)C]-cyanation using biaryl phosphine Pd(0) complexes. J Am Chem Soc 2015, 137: 648–651.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Takahata K, Kimura Y, Seki C, Tokunaga M, Ichise M, Kawamura K, et al. A human PET study of[11C]HMS011, a potential radioligand for AMPA receptors. EJNMMI Res 2017, 7: 63.

Article  PubMed  PubMed Central  Google Scholar 

Oi N, Tokunaga M, Suzuki M, Nagai Y, Nakatani Y, Yamamoto N, et al. Development of novel PET probes for central 2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid receptors. J Med Chem 2015, 58: 8444–8462.

Article  CAS  PubMed  Google Scholar 

Miyazaki T, Nakajima W, Hatano M, Shibata Y, Kuroki Y, Arisawa T, et al. Visualization of AMPA receptors in living human brain with positron emission tomography. Nat Med 2020, 26: 281–288.

Article  CAS  PubMed  Google Scholar 

Arisawa T, Kimura K, Miyazaki T, Takada Y, Nakajima W, Ota W, et al. Synthesis of[18F]fluorine-labeled K-2 derivatives as radiotracers for AMPA receptors. Nucl Med Biol 2022, 110(111): 47–58.

Article  PubMed  Google Scholar 

Manos-Turvey A, Becker G, Francotte P, Serrano ME, Luxen A, Pirotte B, et al. Fully automated synthesis and evaluation of[18 F]BPAM121: Potential of an AMPA receptor positive allosteric modulator as PET radiotracer. ChemMedChem 2019, 14: 788–795.

Article  CAS  PubMed  Google Scholar 

Chen J, Ran W, Huang Y, Wei J, Rong J, Wei H, et al. Evaluation of thiadiazine-based PET radioligands for imaging the AMPA receptor. Biomedecine Pharmacother 2023, 168: 115842.

Article  CAS  Google Scholar 

Nag S, Jia K, Arakawa R, Datta P, Scott D, Shaffer C, et al. Synthesis of[11C]BIIB104, an α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic-acid-positive allosteric modulator, and evaluation of the bio-distribution in non-human primate brains using positron emission tomography. Molecules 2024, 29: 427.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yamazaki M, Le Pichon CE, Jackson AC, Cerpas M, Sakimura K, Scearce-Levie K, et al. Relative contribution of TARPs γ-2 and γ-7 to cerebellar excitatory synaptic transmission and motor behavior. Proc Natl Acad Sci USA 2015, 112: E371–E379.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen Z, Mori W, Zhang X, Yamasaki T, Dunn PJ, Zhang G, et al. Synthesis, pharmacology and preclinical evaluation of 11C-labeled 1, 3-dihydro-2H-benzo[d]imidazole-2-ones for imaging γ8-dependent transmembrane AMPA receptor regulatory protein. Eur J Med Chem 2018, 157: 898–908.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yu Q, Kumata K, Rong J, Chen Z, Yamasaki T, Chen J, et al. Imaging of transmembrane AMPA receptor regulatory proteins by positron emission tomography. J Med Chem 2022, 65: 9144–9158.

Article  CAS  PubMed  PubMed Central  Google Scholar