Mallo, M., Wellik, D. M. & Deschamps, J. Hox genes and regional patterning of the vertebrate body plan. Dev. Biol. 344, 7–15 (2010).
Article CAS PubMed PubMed Central Google Scholar
Mouse Genome Sequencing Consortium. Initial sequencing and comparative analysis of the mouse genome. Nature 420, 520–562 (2002).
Lui, J. H., Hansen, D. V. & Kriegstein, A. R. Development and evolution of the human neocortex. Cell 146, 18–36 (2011).
Article CAS PubMed PubMed Central Google Scholar
Guerin, M. V., Finisguerra, V., Van den Eynde, B. J., Bercovici, N. & Trautmann, A. Preclinical murine tumor models: a structural and functional perspective. eLife 9, e50740 (2020).
Article CAS PubMed PubMed Central Google Scholar
Inoue, T. et al. CYP2C9-catalyzed metabolism of S-warfarin to 7-hydroxywarfarin in vivo and in vitro in chimeric mice with humanized liver. Drug Metab. Dispos. 36, 2429–2433 (2008).
Article CAS PubMed Google Scholar
Sanoh, S. et al. Predictability of metabolism of ibuprofen and naproxen using chimeric mice with human hepatocytes. Drug Metab. Dispos. 40, 2267–2272 (2012).
Article CAS PubMed Google Scholar
Pan, X., Yang, Y. & Zhang, J.-R. Molecular basis of host specificity in human pathogenic bacteria. Emerg. Microbes Infect. 3, e23 (2014).
Article CAS PubMed PubMed Central Google Scholar
Rothenburg, S. & Brennan, G. Species-specific host–virus interactions: implications for viral host range and virulence. Trends Microbiol. 28, 46–56 (2020).
Article CAS PubMed Google Scholar
Peek, R. M. Jr & Blaser, M. J. Helicobacter pylori and gastrointestinal tract adenocarcinomas. Nat. Rev. Cancer 2, 28–37 (2002).
Article CAS PubMed Google Scholar
Miner, J. J. et al. Zika virus infection during pregnancy in mice causes placental damage and fetal demise. Cell 165, 1081–1091 (2016).
Article CAS PubMed PubMed Central Google Scholar
Gladwyn-Ng, I. et al. Stress-induced unfolded protein response contributes to Zika virus-associated microcephaly. Nat. Neurosci. 21, 63–71 (2018).
Article CAS PubMed Google Scholar
Bao, L. et al. The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice. Nature 583, 830–833 (2020).
Article CAS PubMed Google Scholar
Duryee, W. R. & Doherty, J. K. Nuclear and cytoplasmic organoids in the living cell. Ann. N. Y. Acad. Sci. 58, 1210–1231 (1954).
Article CAS PubMed Google Scholar
Pomerat, C. M., Lefeber, C. G. & Smith, M. Quantitative cine analysis of cell organoid activity. Ann. N. Y. Acad. Sci. 58, 1311–1321 (1954).
Article CAS PubMed Google Scholar
Wolter, J. R. Proliferating pigment epithelium. Producing a simple organoid structure in the subrentinal space of a human eye. Arch. Ophthalmol. 77, 651–654 (1967).
Article CAS PubMed Google Scholar
Gordienko, S. M. Organoid teratoma of the nose in an infant. Vestn. Otorinolaringol. 26, 92–94 (1964).
Pinkus, H. Organoid nevus. Mod. Probl. Paediatr. 20, 50–57 (1976).
Hachitanda, Y. & Tsuneyoshi, M. Neuroblastoma with a distinct organoid pattern: a clinicopathologic, immunohistochemical, and ultrastructural study. Hum. Pathol. 25, 67–72 (1994).
Article CAS PubMed Google Scholar
Zimmermann, B. Lung organoid culture. Differentiation 36, 86–109 (1987).
Article CAS PubMed Google Scholar
Lancaster, M. A. & Knoblich, J. A. Organogenesis in a dish: modeling development and disease using organoid technologies. Science 345, 1247125 (2014).
Li, M. L. et al. Influence of a reconstituted basement membrane and its components on casein gene expression and secretion in mouse mammary epithelial cells. Proc. Natl Acad. Sci. USA 84, 136–140 (1987). Bissell and co-workers show that Matrigel can be used to promote 3D structure formation of epithelial cells.
Article CAS PubMed PubMed Central Google Scholar
Eiraku, M. et al. Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals. Cell Stem Cell 3, 519–532 (2008). Eiraku et al. describe self-organization from ESCs.
Article CAS PubMed Google Scholar
Eiraku, M. et al. Self-organizing optic-cup morphogenesis in three-dimensional culture. Nature 472, 51–56 (2011).
Article CAS PubMed Google Scholar
Sato, T. et al. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature 459, 262–265 (2009). Sato et al. describe the establishment of the first TSC-derived organoid from the mouse small intestine.
Article CAS PubMed Google Scholar
Ootani, A. et al. Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche. Nat. Med. 15, 701–706 (2009).
Article CAS PubMed PubMed Central Google Scholar
Sato, T. et al. Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett’s epithelium. Gastroenterology 141, 1762–1772 (2011). Sato et al. describe the establishment of the first hTSC-derived organoid.
Article CAS PubMed Google Scholar
Lancaster, M. A. et al. Cerebral organoids model human brain development and microcephaly. Nature 501, 373–379 (2013). Lancaster et al. establish the first hPSC-derived brain organoids.
Article CAS PubMed PubMed Central Google Scholar
Sampaziotis, F. et al. Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation. Nat. Biotechnol. 33, 845–852 (2015).
Article CAS PubMed PubMed Central Google Scholar
Huch, M. et al. Long-term culture of genome-stable bipotent stem cells from adult human liver. Cell 160, 299–312 (2015).
Article CAS PubMed Google Scholar
Boj, S. F. et al. Organoid models of human and mouse ductal pancreatic cancer. Cell 160, 324–338 (2015).
Article CAS PubMed Google Scholar
Hendriks, D. et al. Human fetal brain self-organizes into long-term expanding organoids. Cell 187, 712–732.e38 (2024).
Article CAS PubMed Google Scholar
Hofbauer, P. et al. Cardioids reveal self-organizing principles of human cardiogenesis. Cell 184, 3299–3317.e22 (2021).
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