Jone, P.-N. et al. Update on diagnosis and management of Kawasaki disease: a scientific statement from the American Heart Association. Circulation 150, e481–e500 (2024).
Soni, P. R., Noval Rivas, M. & Arditi, M. A comprehensive update on Kawasaki disease vasculitis and myocarditis. Curr. Rheumatol. Rep. 22, 6 (2020).
Noval. et al. CD8+ T cells contribute to the development of coronary arteritis in the Lactobacillus casei cell wall extract–induced murine model of Kawasaki disease. Arthritis Rheumatol. 69, 410–421 (2017).
Sugitani Y., Furuno K., Sueishi K., Hara T. Macrophages and cytotoxic T cells infiltrate the destructed mitral tissue in Kawasaki disease. BMJ Case Rep. 2018, bcr-2017–223584 (2018).
Kobayashi, M. et al. Histologic and immunohistochemical evaluation of infiltrating inflammatory cells in Kawasaki disease arteritis lesions. Appl Immunohistochem. Mol. Morphol. 29, 62–67 (2021).
Article CAS PubMed Google Scholar
Sun, M. & Xing, H. Interleukin-35 regulates peripheral T cell activity in patients with Kawasaki disease. Int. Immunopharmacol. 96, 107642 (2021).
Article CAS PubMed Google Scholar
Ye, Q., Gong, F., Shang, S. & Hu, J. Intravenous immunoglobulin treatment responsiveness depends on the degree of CD8 + T cell activation in Kawasaki disease. Clin. Immunol. 171, 25–31 (2016).
Article CAS PubMed Google Scholar
Sohn, S. Y. et al. Alteration of CD4+CD25+Foxp3+T cell level in Kawasaki disease. Korean J. Pediatr. 54, 157 (2011).
Article CAS PubMed PubMed Central Google Scholar
Olivito, B. et al. Defective FOXP3 expression in patients with acute Kawasaki disease and restoration by intravenous immunoglobulin therapy. Clin. Exp. Rheumatol. 28, 93–97 (2010).
Furuno, K. et al. CD25+CD4+ regulatory T cells in patients with Kawasaki disease. J. Pediatrics 145, 385–390 (2004).
Huang, H. et al. The role of FOXO4/NFAT2 signaling pathway in dysfunction of human coronary endothelial cells and inflammatory infiltration of vasculitis in Kawasaki disease. Front. Immunol. 13, 1090056 (2023).
Article PubMed PubMed Central Google Scholar
Sun, Y. et al. The elevated serum levels of calcineurin and nuclear factor of activated T-cells 1 in children with Kawasaki disease. Pediatr. Rheumatol. 18, 23 (2020).
Wang, Y. et al. The role of Ca2+/NFAT in dysfunction and inflammation of human coronary endothelial cells induced by Sera from patients with Kawasaki disease. Sci. Rep. 10, 4706 (2020).
Article CAS PubMed PubMed Central Google Scholar
Suzuki, H. et al. Marker of T-cell activation is elevated in refractory Kawasaki disease. Pediatrics Int. 52, 785–789 (2010).
Matsubara, T. et al. CTLA-4 (CD152) expression in peripheral blood T cells in Kawasaki disease. Clin. Exp. Immunol. 132, 169–173 (2003).
Article CAS PubMed PubMed Central Google Scholar
Wang, Z. et al. Single-cell RNA sequencing of peripheral blood mononuclear cells from acute Kawasaki disease patients. Nat. Commun. 12, 5444 (2021).
Article CAS PubMed PubMed Central Google Scholar
Cao, N. et al. Integration of scRNA-Seq and bulk RNA-Seq uncover perturbed immune cell types and pathways of Kawasaki disease. Front Immunol. 14, 1259353 (2023).
Article CAS PubMed PubMed Central Google Scholar
Chen, Y. et al. Single-cell transcriptome reveals potential mechanisms for coronary artery lesions in Kawasaki disease. ATVB 44, 866–882 (2024).
Wu, Q. et al. Activin a suppresses peripheral CD8+ T lymphocyte activity in acute-phase Kawasaki disease. BMC Immunol. 22, 17 (2021).
Article CAS PubMed PubMed Central Google Scholar
Xu, Y. et al. scRNA+TCR-seq reveals the pivotal role of dual receptor T lymphocytes in the pathogenesis of Kawasaki disease and during IVIG treatment. Front. Immunol. 15, 1457687 (2024).
Article CAS PubMed PubMed Central Google Scholar
Shimizu, C. et al. The role of TGF-β and myofibroblasts in the arteritis of Kawasaki disease. Hum. Pathol. 44, 189–198 (2013).
Article CAS PubMed Google Scholar
Wakiguchi, H. et al. Relationship between T-cell HLA-DR expression and intravenous immunoglobulin treatment response in Kawasaki disease. Pediatr. Res. 77, 536–540 (2015).
Article CAS PubMed Google Scholar
Wang, N. et al. Intravenous immunoglobulin therapy restores the quantity and phenotype of circulating dendritic cells and CD4+ T cells in children with acute Kawasaki disease. Front. Immunol. 13, 802690 (2022).
Article CAS PubMed PubMed Central Google Scholar
Xie, Z. et al. Atlas of circulating immune cells in Kawasaki disease. Int. Immunopharmacol. 102, 108396 (2022).
Article CAS PubMed Google Scholar
Guiducci, S. et al. Microparticles and Kawasaki disease: a marker of vascular damage? Clin. Exp. Rheumatol. 29, S121–S125 (2011).
Poddighe, D. et al. Double-negative T cells in pediatric rheumatic diseases. Clin. Exp. Pediatr. 67, 632–640 (2024).
Article CAS PubMed PubMed Central Google Scholar
Consiglio, C. R. et al. The immunology of multisystem inflammatory syndrome in children with COVID-19. Cell 183, 968–981.e7 (2020).
Article CAS PubMed PubMed Central Google Scholar
Ghosh, P. et al. An Artificial Intelligence-guided signature reveals the shared host immune response in MIS-C and Kawasaki disease. Nat. Commun. 13, 2687 (2022).
Article CAS PubMed PubMed Central Google Scholar
Sharma, C. et al. Multisystem inflammatory syndrome in children and Kawasaki disease: a critical comparison. Nat. Rev. Rheumatol. 17, 731–748 (2021).
Article CAS PubMed PubMed Central Google Scholar
Zhang, C. et al. Predictive role of IL-2R and IL-10 in the anti-inflammatory response and antiplatelet therapy of Kawasaki disease: a retrospective study. Mediators Inflamm. 2022, 1–13 (2022).
Netea, S. A. et al. Transient anti-cytokine autoantibodies superimpose the hyperinflammatory response in Kawasaki disease and multisystem inflammatory syndrome in children: a comparative cohort study on correlates of disease. eBioMedicine 95, 104736 (2023).
Article CAS PubMed PubMed Central Google Scholar
Balestrieri, E. et al. Preliminary evidence of the differential expression of human endogenous retroviruses in Kawasaki disease and SARS-CoV-2-associated multisystem inflammatory syndrome in children. IJMS 24, 15086 (2023).
Article CAS PubMed PubMed Central Google Scholar
Hsieh, L.-E. et al. Intravenous immunoglobulin induces IgG internalization by tolerogenic myeloid dendritic cells that secrete IL-10 and expand Fc-specific regulatory T cells. Clin. Exp. Immunol. 208, 361–371 (2022).
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