Biological activity of isomalabaricane compounds from the marine sponge

Mehbub MF, Yang Q, Cheng Y, Franco CMM, Zhang W (2024) Marine sponge-derived natural products: trends and opportunities for the decade of 2011–2020. Front Mar Sci. https://doi.org/10.3389/fmars.2024.1462825

Article  Google Scholar 

Bergmann W, BURKE DC (1955) Contributions to the study of marine products. XXXIX. The nucleosides of sponges. III. 1 spongothymidine and spongouridine2. J Org Chem 20:1501–1507

Article  CAS  Google Scholar 

Jackson KL, Henderson JA, Phillips AJ (2009) The halichondrins and E7389. Chem Rev 109:3044–3079. https://doi.org/10.1021/cr900016w

Article  CAS  PubMed  Google Scholar 

Uemura D, Takahashi K, Yamamoto T, Katayama C, Tanaka J, Okumura Y, Hirata Y (1985) Norhalichondrin A: an antitumor polyether macrolide from a marine sponge. J Am Chem Soc 107:4796–4798. https://doi.org/10.1021/ja00302a042

Article  CAS  Google Scholar 

Hirata Y, Uemura D (1986) Halichondrins-antitumor polyether macrolides from a marine sponge. Pure Appl Chem 58:701–710

Article  CAS  Google Scholar 

Pettit GR, Herald CL, Boyd MR, Leet JE, Dufresne C, Doubek DL, Schmidt JM, Cerny RL, Hooper JNA, Rutzler KC (1991) Antineoplastic agents. 219. Isolation and structure of the cell growth inhibitory constituents from the western Pacific marine sponge Axinella sp. J Med Chem 34:3339–3340. https://doi.org/10.1021/jm00115a027

Article  CAS  PubMed  Google Scholar 

Quiñoà E, Crews P (1987) Phenolic constituents of Psammaplysilla. Tetrahedron Lett 28:3229–3232. https://doi.org/10.1016/S0040-4039(00)95478-9

Article  Google Scholar 

Santaniello G, Nebbioso A, Altucci L, Conte M (2022) Recent advancement in anticancer compounds from marine organisms: approval, use and bioinformatic approaches to predict new targets. Mar Drugs 21:24

Article  PubMed  PubMed Central  Google Scholar 

Lucena-Agell D, Guillén MJ, Matesanz R, Álvarez-Bernad B, Hortigüela R, Avilés P, Martínez-Díez M, Santamaría-Núñez G, Contreras J, Plaza-Menacho I et al (2024) PM534, an optimized target-protein interaction strategy through the colchicine site of tubulin. J Med Chem 67:2619–2630. https://doi.org/10.1021/acs.jmedchem.3c01775

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cruz PG, Fernández R, Rodríguez-Acebes R, Martínez-Díez M, Santamaría-Núñez G, Pérez M, Cuevas C (2024) From sea sponge to clinical trials: starting the journey of the novel compound PM742. Mar Drugs. https://doi.org/10.3390/md22080339

Article  PubMed  PubMed Central  Google Scholar 

Chan GW, Mong S, Hemling ME, Freyer AJ, Offen PH, DeBrosse CW, Sarau HM, Westley JW (1993) New leukotriene B4 receptor antagonist: leucettamine A and related imidazole alkaloids from the marine sponge Leucetta microraphis. J Nat Prod 56:116–121. https://doi.org/10.1021/np50091a016

Article  CAS  PubMed  Google Scholar 

Lindberg MF, Deau E, Miege F, Greverie M, Roche D, George N, George P, Merlet L, Gavard J, Brugman SJT et al (2023) Chemical, biochemical, cellular, and physiological characterization of leucettinib-21, a Down syndrome and Alzheimer’s disease drug candidate. J Med Chem 66:15648–15670. https://doi.org/10.1021/acs.jmedchem.3c01888

Article  CAS  PubMed  Google Scholar 

Stonik VA, Kolesnikova SA (2021) Malabaricane and isomalabaricane triterpenoids, including their glycoconjugated forms. Mar Drugs 19:327

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cárdenas P, Gamage J, Hettiarachchi CM, Gunasekera S (2022) Good practices in sponge natural product studies: revising vouchers with isomalabaricane triterpenes. Mar Drugs 20:190

Article  PubMed  PubMed Central  Google Scholar 

Kolesnikova SA, Kozhushnaya AB, Shilov VA, Kukhlevsky AD, Kalinovsky AI, Popov RS, Dmitrenok PS, Ivanchina NV (2025) Isomalabaricane chemical composition of Vietnamese marine sponges inspected by metabolomic and chemical approaches. Mar Drugs. https://doi.org/10.3390/md23120466

Article  PubMed  PubMed Central  Google Scholar 

Wang R, Zhang Q, Peng X, Zhou C, Zhong Y, Chen X, Qiu Y, Jin M, Gong M, Kong D (2016) Stellettin B induces G1 arrest, apoptosis and autophagy in human non-small cell lung cancer A549 cells via blocking PI3K/Akt/mTOR pathway. Sci Rep 6:27071

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tsai T-C, Wu W-T, Lin J-J, Su J-H, Wu Y-J (2022) Stellettin B isolated from Stelletta sp. reduces migration and invasion of hepatocellular carcinoma cells through reducing activation of the MAPKs and FAK/PI3K/AKT/mTOR signaling pathways. Int J Cell Biol 2022:4416611. https://doi.org/10.1155/2022/4416611

Article  CAS  PubMed  PubMed Central  Google Scholar 

Peng X, Zhang S, Wang Y, Zhou Z, Yu Z, Zhong Z, Zhang L, Chen Z-S, Claret FX, Elkabets M et al (2023) Stellettin B sensitizes glioblastoma to DNA-damaging treatments by suppressing PI3K-mediated homologous recombination repair. Adv Sci 10:2205529. https://doi.org/10.1002/advs.202205529

Article  CAS  Google Scholar 

Feng C-W, Chen N-F, Wen Z-H, Yang W-Y, Kuo H-M, Sung P-J, Su J-H, Cheng S-Y, Chen W-F (2019) In vitro and in vivo neuroprotective effects of Stellettin B through anti-apoptosis and the Nrf2/HO-1 pathway. Mar Drugs. https://doi.org/10.3390/md17060315

Article  PubMed  PubMed Central  Google Scholar 

Kozhushnaya AB, Kolesnikova SA, Yurchenko EA, Lyakhova EG, Menshov AS, Kalinovsky AI, Popov RS, Dmitrenok PS, Ivanchina NV (2023) Rhabdastrellosides A and B: two new isomalabaricane glycosides from the marine sponge Rhabdastrella globostellata, and their cytotoxic and cytoprotective effects. Mar Drugs. https://doi.org/10.3390/md21110554

Article  PubMed  PubMed Central  Google Scholar 

Kolesnikova SA, Lyakhova EG, Kozhushnaya AB, Kalinovsky AI, Berdyshev DV, Popov RS, Stonik VA (2021) New isomalabaricane-derived metabolites from a Stelletta sp. marine sponge. Molecules. https://doi.org/10.3390/molecules26030678

Article  PubMed  PubMed Central  Google Scholar 

Dyshlovoy SA, Fedorov SN, Shubina LK, Kuzmich AS, Bokemeyer C, von Keller- Amsberg G, Honecker F (2014) Aaptamines from the marine sponge Aaptos sp. display anticancer activities in human cancer cell lines and modulate AP-1-, NF- κ B-, and p53-dependent transcriptional activity in mouse JB6 Cl41 cells. Biomed Res Int 2014:469309. https://doi.org/10.1155/2014/469309

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sousa B, Melo T, Campos A, Moreira ASP, Maciel E, Domingues P, Carvalho RP, Rodrigues TR, Girão H, Domingues MRM (2016) Alteration in phospholipidome profile of myoblast H9c2 cell line in a model of myocardium starvation and ischemia. J Cell Physiol 231:2266–2274. https://doi.org/10.1002/jcp.25344

Article  CAS  PubMed  Google Scholar 

Petrosillo G, Venosa ND, Pistolese M, Casanova G, Tiravanti E, Colantuono G, Federici A, Paradies G, Ruggiero FM (2006) Protective effect of melatonin against mitochondrial dysfunction associated with cardiac ischemiareperfusion: role of cardiolipin. FASEB J 20:269–276. https://doi.org/10.1096/fj.05-4692com

Article  CAS  PubMed  Google Scholar 

Fernandez MG, Troiano L, Moretti L, Nasi M, Pinti M, Salvioli S, Dobrucki J, Cossarizza A (2002) Early changes in intramitochondrial cardiolipin distribution during apoptosis1. Cell Growth Differ 13:449–455

CAS  Google Scholar 

Yin H, Zhu M (2012) Free radical oxidation of cardiolipin: chemical mechanisms, detection and implication in apoptosis, mitochondrial dysfunction and human diseases. Free Radic Res 46:959–974. https://doi.org/10.3109/10715762.2012.676642

Article  CAS  PubMed  Google Scholar 

Lyamzaev KG, Sumbatyan NV, Nesterenko AM, Kholina EG, Voskoboynikova N, Steinhoff H-J, Mulkidjanian AY, Chernyak BV (2019) MitoCLox: a novel mitochondria-targeted fluorescent probe for tracing lipid peroxidation. Oxid Med Cell Longev. https://doi.org/10.1155/2019/9710208

Article  PubMed  PubMed Central  Google Scholar 

Guerra Martinez C (2019) P2X7 receptor in cardiovascular disease: the heart side. Clin Exp Pharmacol Physiol 46:513–526. https://doi.org/10.1111/1440-1681.13079

Article  CAS  PubMed  Google Scholar 

Tripathi VK, Subramaniyan SA, Hwang I

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