Abdulla D, Goralski KB, Garcia Del Busto Cano E, Renton KW (2005) The signal transduction pathways involved in hepatic cytochrome p450 regulation in the rat during a lipopolysaccharide-induced model of central nervous system inflammation. Drug Metab Dispos 33:1521–1531. https://doi.org/10.1124/DMD.105.004564
Article CAS PubMed Google Scholar
Adamu A, Li S, Gao F, Xue G (2024) The role of neuroinflammation in neurodegenerative diseases: current understanding and future therapeutic targets. Front Aging Neurosci 16:1347987. https://doi.org/10.3389/FNAGI.2024.1347987/PDF
Article CAS PubMed PubMed Central Google Scholar
Batista CRA, Gomes GF, Candelario-Jalil E et al (2019) Lipopolysaccharide-induced neuroinflammation as a bridge to understand neurodegeneration. Int J Mol Sci 20:2293. https://doi.org/10.3390/IJMS20092293
Article CAS PubMed PubMed Central Google Scholar
Bignami A, Hosley M, Dahl D (1993) Hyaluronic acid and hyaluronic acid-binding proteins in brain extracellular matrix. Anat Embryol (Berl) 188:419–433. https://doi.org/10.1007/BF00190136
Article CAS PubMed Google Scholar
Camunas-Alberca SM, Moran-Garrido M, Sáiz J et al (2023) The role of oxylipins and their validation as biomarkers in the clinical context. TrAC Trends Anal Chem 164:117065. https://doi.org/10.1016/J.TRAC.2023.117065
Catorce MN, Gevorkian G (2016) LPS-induced murine neuroinflammation model: main features and suitability for pre-clinical assessment of nutraceuticals. Curr Neuropharmacol 14:155. https://doi.org/10.2174/1570159X14666151204122017
Article CAS PubMed PubMed Central Google Scholar
Chistyakov DV, Astakhova AA, Sergeeva MG (2018) Resolution of inflammation and mood disorders. Exp Mol Pathol 105:190–201. https://doi.org/10.1016/j.yexmp.2018.08.002
Article CAS PubMed Google Scholar
Chistyakov DVDV, Nikolskaya AI, Goriainov SVSV et al (2020a) Inhibitor of hyaluronic acid synthesis 4-methylumbelliferone as an anti-inflammatory modulator of LPS-mediated astrocyte responses. Int J Mol Sci 21:1–16. https://doi.org/10.3390/ijms21218203
Chistyakov DV, Gavrish GE, Goriainov SV et al (2020b) Oxylipin profiles as functional characteristics of acute inflammatory responses in astrocytes pre-treated with IL-4, IL-10, or LPS. Int J Mol Sci 21:1780. https://doi.org/10.3390/ijms21051780
Article CAS PubMed PubMed Central Google Scholar
Chistyakov DV, Azbukina NV, Lopachev AV et al (2024) Plasma oxylipin profiles reflect Parkinson’s disease stage. Prostaglandins Other Lipid Mediat 171:106788. https://doi.org/10.1016/J.PROSTAGLANDINS.2023.106788
Article CAS PubMed Google Scholar
Da Ré C, Souza JM, Fróes F et al (2020) Neuroinflammation induced by lipopolysaccharide leads to memory impairment and alterations in hippocampal leptin signaling. Behav Brain Res 379:112360. https://doi.org/10.1016/j.bbr.2019.112360
Article CAS PubMed Google Scholar
Dennis EA, Norris PC (2015) Eicosanoid storm in infection and inflammation. Nat Rev Immunol 15:511–523. https://doi.org/10.1038/nri3859
Article CAS PubMed PubMed Central Google Scholar
Dubisova J, Burianova JS, Svobodova L et al (2022) Oral treatment of 4-methylumbelliferone reduced perineuronal nets and improved recognition memory in mice. Brain Res Bull 181:144–156. https://doi.org/10.1016/j.brainresbull.2022.01.011
Article CAS PubMed PubMed Central Google Scholar
Elisia I, Nakamura H, Lam V et al (2016) DMSO represses inflammatory cytokine production from human blood cells and reduces autoimmune arthritis. PLoS ONE 11:e0152538. https://doi.org/10.1371/JOURNAL.PONE.0152538
Article PubMed PubMed Central Google Scholar
Fan LW, Tien LT, Zheng B et al (2011) Dopaminergic neuronal injury in the adult rat brain following neonatal exposure to lipopolysaccharide and the silent neurotoxicity. Brain Behav Immun 25:286–297. https://doi.org/10.1016/j.bbi.2010.09.020
Article CAS PubMed Google Scholar
Gabbs M, Leng S, Devassy JG et al (2015) Advances in our understanding of oxylipins derived from dietary PUFAs. Adv Nutr 6:513–540. https://doi.org/10.3945/an.114.007732
Article CAS PubMed PubMed Central Google Scholar
Galgoczi E, Jeney F, Katko M et al (2020) Characteristics of hyaluronan synthesis inhibition by 4-methylumbelliferone in orbital fibroblasts. Investig Ophthalmol vis Sci 61:27. https://doi.org/10.1167/iovs.61.2.27
Gilroy DW, Newson J, Sawmynaden P et al (2004) A novel role for phospholipase A 2 isoforms in the checkpoint control of acute inflammation. FASEB J 18:489–498. https://doi.org/10.1096/FJ.03-0837COM
Article CAS PubMed Google Scholar
Hasanzadeh E, Seifalian A, Mellati A et al (2023) Injectable hydrogels in central nervous system: unique and novel platforms for promoting extracellular matrix remodeling and tissue engineering. Mater Today Bio 20:100614. https://doi.org/10.1016/j.mtbio.2023.100614
Article CAS PubMed PubMed Central Google Scholar
Hennebelle M, Metherel AH, Kitson AP et al (2019) Brain oxylipin concentrations following hypercapnia/ ischemia: effects of brain dissection and dissection time. J Lipid Res 60:671–682. https://doi.org/10.1194/jlr.D084228
Article CAS PubMed Google Scholar
Iloun P, Abbasnejad Z, Janahmadi M et al (2018) Investigating the role of P38, JNK and ERK in LPS induced hippocampal insulin resistance and spatial memory impairment: effects of insulin treatment. EXCLI J 17:825. https://doi.org/10.17179/EXCLI2018-1387
Article PubMed PubMed Central Google Scholar
Kakizaki I, Kojima K, Takagaki K et al (2004) A novel mechanism for the inhibition of hyaluronan biosynthesis by 4-methylumbelliferone. J Biol Chem 279:33281–33289. https://doi.org/10.1074/jbc.M405918200
Article CAS PubMed Google Scholar
Kultti A, Pasonen-Seppänen S, Jauhiainen M et al (2009) 4-Methylumbelliferone inhibits hyaluronan synthesis by depletion of cellular UDP-glucuronic acid and downregulation of hyaluronan synthase 2 and 3. Exp Cell Res 315:1914–1923. https://doi.org/10.1016/j.yexcr.2009.03.002
Article CAS PubMed Google Scholar
Lawson MA, Parrott JM, McCusker RH et al (2013) Intracerebroventricular administration of lipopolysaccharide induces indoleamine-2,3-dioxygenase-dependent depression-like behaviors. J Neuroinflammation 10:87. https://doi.org/10.1186/1742-2094-10-87
Article CAS PubMed PubMed Central Google Scholar
Leal LE, Moreira ES, Correia BL et al (2024) Comparative study of the antioxidant and anti-inflammatory effects of the natural coumarins 1,2-benzopyrone, umbelliferone and esculetin: in silico, in vitro and in vivo analyses. Naunyn Schmiedebergs Arch Pharmacol 397:173–187. https://doi.org/10.1007/S00210-023-02606-2
Article CAS PubMed Google Scholar
Li F, Hao P, Liu G et al (2017) Effects of 4-methylumbelliferone and high molecular weight hyaluronic acid on the inflammation of corneal stromal cells induced by LPS. Graefes Arch Clin Exp Ophthalmol 255:559–566. https://doi.org/10.1007/s00417-016-3561-1
Article CAS PubMed Google Scholar
Lund S, Christensen KV, Hedtjärn M et al (2006) The dynamics of the LPS triggered inflammatory response of murine microglia under different culture and in vivo conditions. J Neuroimmunol 180:71–87. https://doi.org/10.1016/j.jneuroim.2006.07.007
Comments (0)